Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7405296 | Additives for fluorinated oils Compounds of formula wherein Rf is a (per)fluoropolyoxyalkylene chain having a number average molecular weight in the range 500-10,000; W1, W2 | 07/29/2008 |
| 7354924 | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives This invention provides Compounds I having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral acti... | 04/08/2008 |
| 7332105 | Synergistic UV absorber combination A stabilizer composition comprising (A) a compound of the formula (I) wherein R is (CH2—CH2—O—)n, —R2; —CH2—CH(OH)—CH2—O—R2; or —CH(R3)—CO—O—R4 | 02/19/2008 |
| 7300978 | Functionalised polymers This invention relates to a process for stabilising and at the same time phase compatibilising plastics or plastic compositions by incorporating polymeric compounds obtainable by reacting a compound selected from the group consisting of the sterically hindered pheno... | 11/27/2007 |
| 7268228 | Optically active aziridine-2-carboxylate derivatives and a process for preparing them This invention relates to compounds of Formula I having an aziridine-2-carboxylic group and a menthol group, a process for preparing such compounds, a method for obtaining optically active aziridine-2-carboxylate derivatives by optical resolution of such compounds, ... | 09/11/2007 |
| 7265171 | Transparent polymer articles of low thickness The novel transparent polyolefin, polyester or polyamide article disclosed is stabilized against the effects of light, oxygen, heat and agressive chemicals by addition of 0.005-0.30% by weight the polymeric substrate of a hydroxyphenyl triazine UV absorber, and is c... | 09/04/2007 |
| 7229988 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses The present invention provides novel dialkylhydroxybenzoic acid derivatives containing metal chelating groups and the use of the novel compounds as therapeutics for treating and/or preventing various medical dysfunctions and diseases arising from reactive oxygen spe... | 06/12/2007 |
| 7230098 | Aminoheteroaryl compounds as protein kinase inhibitors Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET ... | 06/12/2007 |
| 7214742 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks Compounds of the general formula I′ in which R1 is H, C1–C12alkyl; C5–C12cycloalkyl; C2–C18alkyl which is interrup... | 05/08/2007 |
| 7135471 | Aryl oximes Aryl oxime derivatives of the formula (I), in which R1, R2, R3, X and B are as defined in claim 1, act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosi... | 11/14/2006 |
| 7129241 | Pyridazine derivatives Pyridazine derivatives of the formula (I) act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies... | 10/31/2006 |
| 7122547 | Anthranilic acid amides and the use thereof as medicaments The invention relates to anthranilic acid amides and the use thereof as medicaments for the treatment of diseases that are triggered by persistent angiogenesis, in addition to intermediate products in the production of anthranilic acid amides. ... | 10/17/2006 |
| 7119210 | Dual function UV-absorbers for ophthalmic lens materials Disclosed are UV absorbers that contain a labile functional group capable of initiating free radical polymerization. ... | 10/10/2006 |
| 7066990 | Ink jet ink and recording material The present invention relates to an ink jet ink, an ink jet recording material or an ink jet system comprising at least one compound selected from the group consisting of a) the dialkyl hydroxylamine stabilizers, b) the nitrone stabilizers and c) the amine oxide sta... | 06/27/2006 |
| 7064125 | LPAAT-β inhibitors and uses thereof The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for ... | 06/20/2006 |
| 7030266 | Method for producing polyisocyanates The invention relates to a method for making oligomeric isocyanates by reacting diisocyanates in the presence of a catalyst, wherein the catalyst comprises a saline compound prepared from a five-membered N-heterocycles and the N-heterocycle comprises at least one Nâ... | 04/18/2006 |
| 7026477 | Process for preparing substituted phenylsulfonylureas from sulfonyl halides The invention relates to a preparation process for a compound (I) or a salt thereof, in which Q, X*, Y, Z, R, R1, R2 and R3 are as defined in claim 1, | 04/11/2006 |
| 7026307 | Method for producing 1,3-disubstituted 2-nitroguanidines The present invention relates to a process for the preparation of compounds of the formula (I) by reacting compounds of the formula (II) in which ... | 04/11/2006 |
| 7018966 | Compositions and methods for preventing gel formation comprising a siloxane and an alkylamine The present invention relates to a cleaning composition comprising an emulsion comprising a polar co-solvent, a non-polar co-solvent, and an alkylamine dispersed throughout the emulsion. The alkylamine serves to prevent the emulsion from inverting and forming a thic... | 03/28/2006 |
| 6903097 | Heterocycle carboxamides as antiviral agents The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family. ... | 06/07/2005 |
| 6867250 | Non-yellowing ortho-dialkyl aryl substituted triazine ultraviolet light absorbers The invention relates generally to pyrimidines and triazines ultraviolet light absorbers containing a phenolic aromatic group(s) and a non-phenolic aromatic group(s) and the use thereof to protect against degradation by environmental forces, inclusive of ultraviolet... | 03/15/2005 |
| 6855269 | Phenyl ether-substituted hydroxyphenyl triazine ultraviolet light absorbers This invention relates generally to phenyl ether substituted triazines compounds and compositions containing same and their use to protect against degradation by environmental forces. A method for stabilizing a material by incorporating such triazines is also disclo... | 02/15/2005 |
| 6846818 | Selective inhibitors of cyclooxygenase-2 The present invention relates to cyclooxygenase-2 (COX-2) selective inhibitors of formula I: pharmaceutical compositions containing them, to their medicinal use, and to their preparations. The compounds of the inventio... | 01/25/2005 |
| 6838415 | Substituted benzoylisoxazoles and the use thereof as herbicides The invention relates to novel substituted benzoylisoxazoles of the general formula (I), in which n represents the number 0, 1, 2 or 3, A represents a single bond or ... | 01/04/2005 |
| 6835329 | Heteroaryl substituted hydroxyphenyltriazine uv-absorbers The present invention provides compounds having the formula (1) in which each of the radicals R1, R2, R3 and R4, independently, represent hydrogen, hydroxy, halogen, C1-C20-alkyl, C1-C... | 12/28/2004 |
| 6803349 | Heterocyclic ring-containing compound and a lubricant composition using the same A heterocyclic ring-containing compound represented by the following formula (1). In the formula, D represents a heterocyclic ring residue having a 5- to 7-membered ring structure and substituted with (m+n) of substituents, X represents a divalent linking group cons... | 10/12/2004 |
| 6773861 | UV absorbent and preparation method thereof, compositions and image forming method A UV absorbent represented by the following formula (1) [R1 represents an alkenyl group, all of R1 represent the same group, and R2, R3 and R4 independently represent a hydrogen atom, an alkyl group, an alkoxy g... | 08/10/2004 |
| 6759407 | Acyclic and cyclic guanidine- and acetamidine derivatives, their preparation and their use as pesticides, ESP as parasiticides Novel pesticides of formula (I) wherein the substituents, R, R1, R2, R2′, T, U, X and Y are as defined in claim 1, are described. Also described are compositions suitable for use as par... | 07/06/2004 |
| 6730785 | Process for making triazine UV absorbers using lewis acids and reaction promoters It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence o... | 05/04/2004 |
| 6706743 | β3 adrenergic receptor agonists and uses thereof The instant invention provides β3 adrenergic receptor agonists of structural Formula (I), the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds, stereoisomers and ... | 03/16/2004 |
| 6677353 | Substituted N-phenyl-N-heteroaralkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 01/13/2004 |
| 6677341 | (R)-Chiral halogenated substituted heteroaryl benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and m... | 01/13/2004 |
| 6664391 | N-fluorotriazinium fluorinating agents Novel N-fluorotriazinium electrophilic fluorinating agents have the Formula I: ##STR1## wherein three A moieties are independently CR, where each R is, independently, hydrogen, halogen, hydroxyl, (primary, secondary or tertiary) amino, amino, cyano, ... | 12/16/2003 |
| 6635760 | Ring fluorination of non-activated aromatic compounds Aromatic compounds having one or more electron-withdrawing substituents are fluorinated, preferably in a nitromethane solvent, by contact with tri(halo- or trifluoromethyl) substituted N-fluorotriazinium salts of the following Formula I: ##STR1## whe... | 10/21/2003 |
| 6624166 | Pyridazines as interleukin-1ଲ converting enzyme inhibitors Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein R1 is a halogen, or an oxygen linked leaving group including an aromatic ether, an alkyl sulfonate, an aryl sulfonate, an alkyl ... | 09/23/2003 |
| 6617325 | Biphenyl derivatives, production thereof and uses as medicines The present invention relates to biphenyl derivatives of general formula ##STR1## wherein Ra to Rg and n are defined as in claim 1, the isomers and salts thereof, particularly the physiologically acceptable salts thereof, which are v... | 09/09/2003 |
| 6573219 | Substituted heterocyclyl-2H-chromenes The invention relates to novel substituted heterocyclyl-2H-chromenes of the general formula (I) ##STR1## in which R1, R2, R3, R4, R5 Z are each as defined in the description, and to a process for thei... | 06/03/2003 |
| 6559100 | 2-benzoyl-cyclohexane-1,3-diones Substituted 2-benzoylcyclohexane-1,3-diones of the formula I ##STR1## where: R1 and R2 are each hydrogen, mercapto, nitro, halogen, cyano, thiocyanato, C1 -C6 -alkyl, C1 -C6 -haloalkyl, C1 | 05/06/2003 |
| 6555682 | Two-photon responsive chromophores containing electron accepting cores Provided are chromophores of the formula Q--(--L--Z)x, wherein x is 3 or 4, wherein Q is selected from the group consisting of ##STR1## wherein L is selected from the group consisting of ##STR2## wherein R is an alkyl group having 1 to 20 carbon ato... | 04/29/2003 |
| 6528648 | Detecting reagent for double-stranded nucleic acid and double-stranded nucleic acid detecting method The present invention provides a novel detecting reagent for double-stranded nucleic acid, and a method of using it to detect double-stranded nucleic acid formed by hybridization with a probe, with absolutely no labeling of the target nucleic acid. The de... | 03/04/2003 |
