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| Number | Title | Issue Date |
| 7700770 | Methods for isolating crystalline form I of 5-azacytidine The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical composition... | 04/20/2010 |
| 7410968 | Capped pyrazinoylguanidine sodium channel blockers The present invention relates to compounds represented by formula (I): where the structural variables are as defined herein. The compounds are useful for promoting hydration of mucosal surfaces. ... | 08/12/2008 |
| 7358252 | 4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl)pyrazolo-[1,5-a]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands Corticotropin releasing factor (CRF) antagonists of Formula (I): and its use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart-rela... | 04/15/2008 |
| 7319099 | Benzoyl-piperazine derivatives The invention relates to compounds of formula wherein the substituents are described herein. The compounds may be used in the treatment of illnesses based on the glycine uptake inhibitor, such as psychoses, pain,... | 01/15/2008 |
| 7309711 | Fungicidal agent combinations The invention relates to novel fungicidallly active compound combinations of 2′-cyano-3,4-dichloroisothiazole-5-carboxanilide of the formula and the active compounds listed in the disclosure. ... | 12/18/2007 |
| 7288572 | Active substance combinations having insecticidal and acaricidal properties The present invention relates to novel insecticidally and acaricidally active compound combinations of N2-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide of the form... | 10/30/2007 |
| 7285550 | Triazolotriazines and pyrazolotriazines and methods of making and using the same The invention is based on the discovery that compounds of formula (I) possess unexpectedly high affinity for the A2a adenosine receptor, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including Parkinson's disea... | 10/23/2007 |
| 7259163 | 4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as HCV inhibitors Novel anti-viral agents of Formula wherein: A represents OR1, NR1R2, or R1 wherein R1 and R2 are hydrogen, C1-6alkyl, aryl... | 08/21/2007 |
| 7230100 | Stereoselective method for the preparation of nucleosides A process for producing predominantly cis nucleosides or nucleoside analogues and derivatives of formula (A): wherein R1 is a pyrimidine base or a pharmaceutically acceptable derivative thereof and Q is oxygen, c... | 06/12/2007 |
| 7214259 | Inks containing water-soluble perylene dyes and their use in ink-jet printing An ink comprising a liquid medium and a colorant, wherein the liquid medium comprises water and a water-miscible organic solvent and the colorant is of Formula (1), wherein the colorant is dissolved in the liquid medium: Formula (1) wherein: each independently is a ... | 05/08/2007 |
| 7214701 | Active substance combinations having insecticidal and acaricdal properties The invention relates to insecticidal mixtures for protecting plants against attack by pests comprising (a) compounds of the formula (I) ... | 05/08/2007 |
| 7208597 | Pyridyl-triazine derivatives as microbiocidal active substances Triazine derivatives of formula (1) wherein R1 is C1–C20alkyl; C3–C7cycloalkyl; or C1–C20perfluoroalkyl; R2 is hydrogen; C1–C20alkyl; or C3 | 04/24/2007 |
| 7186865 | Optically active 1-(fluoro-, trifluoromethyl-or trifluoromethoxy-substituted phenyl) alkylamine n-monoalkyl derivatives and process for producing same An optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy-substituted phenyl)alkylamine N-monoalkyl derivative represented by the formula 4 is produced by a process including (a) reacting an optically active secondary amine, represented by the formula 1, ... | 03/06/2007 |
| 7157578 | 4-(2-butylamino)-2, 7-dimethyl-8-(2-methyl-6-methoxypyrid-3-YL) pyrazolo-[1,5-A]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands Corticotropin releasing factor (CRF) antagonists of Formula (I): and its use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or... | 01/02/2007 |
| 7148240 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same The invention relates to benzofuran or benzothiophene derivatives of general formula: These compounds are of use as medicinal products, in particular in the treatment of pathological syndromes of the cardiovascular... | 12/12/2006 |
| 7135499 | Active substance combinations having insecticidal and acaricidal properties The present invention relates to novel insecticidally and acaricidally active compound combinations of N2-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide of the form... | 11/14/2006 |
| 7084138 | Active ingredient combinations with insecticidal and acaricidal properties The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing (a) cyclic ketoenols having the formula in which the gro... | 08/01/2006 |
| 7078518 | Forms of 5-Azacytidine The disclosure includes novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The disclosure... | 07/18/2006 |
| 7064129 | Capped pyrazinoylguanidine sodium channel blockers Compounds are provided which are represented by the formula: where the structural variables are defined herein. The present invention also includes a variety of methods of treatment using these inventive sodium c... | 06/20/2006 |
| 7008798 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods The present invention pertains to luminescent dyes and methods for covalently attaching the dyes to a component or mixture of components so that the components may be detected and/or quantified by luminescence detection methods. The dyes are cyanine and cyanine-type... | 03/07/2006 |
| 7002011 | Process for the preparation of 2-amino-4-chloro-1,3,5-triazines Compounds of the formula (I) or salts thereof are suitable for preparing active substances from the from the class of the aminotriazines of the formula (IV), for example herbicidal active substances. The compounds (I) c... | 02/21/2006 |
| 7001903 | Synergistic insecticidal mixtures The invention relates to insecticidal mixtures of spinosyns and agonists or antagonists of nicotinic acetylcholine receptors for protecting plants against attack by pests. ... | 02/21/2006 |
| 6998272 | Macrocyclic compounds and their use The subject invention pertains to macrocyclic compounds, and their use, the compounds having the formula (I) wherein X is a ring bearing an optionally-protected functional group or solid phase group R1, Y is ... | 02/14/2006 |
| 6995262 | Use of acylsulfonamido-substituted polymethine dyes as fluorescene dyes and/or markers The invention relates to a novel polymethine dyes containing at least one acylsulfonamido group of the formula (I) in which n, Y, A and R have the meaning given in the claims, and at least one compound of the formulae ... | 02/07/2006 |
| 6989275 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods The present invention pertains to luminescent dyes and methods for covalently attaching the dyes to a component or mixture of components so that the components may be detected and/or quantified by luminescence detection methods. The dyes are cyanine and cyanine-type... | 01/24/2006 |
| 6979719 | Coating composition comprising a compound comprising at least one bicyclo-orthoester group and at least one other functional group The invention pertains to a coating composition comprising a compound comprising at least one bicyclo-orthoester group and at least one other functional group. The invention also comprises a process for curing the present coating composition. Further, a process for ... | 12/27/2005 |
| 6958341 | Pyrazolopyrimidines as CRF antagonists The present invention relates to pyrazolopyrimidines according to formula (I) and stereoisomers, isomers and salts thereof wherein R1-R5 are selected from certain alkyl, aryl and heteroaryl specie... | 10/25/2005 |
| 6956032 | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods The present invention pertains to luminescent dyes and methods for covalently attaching the dyes to a component or mixture of components so that the components may be detected and/or quantified by luminescence detection methods. The dyes are cyanine and cyanine-type... | 10/18/2005 |
| 6953798 | β-alanine derivates Alkanoic acid derivatives of formula (1) are described: Ar1(Alka)rL1Ar2CH(R1)C(Ra)(Ra′)R (1) Ar1 is an optionally substituted aromatic or... | 10/11/2005 |
| 6949544 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases The present invention provide a compound of formula I or II: or a pharmaceutically acceptable derivative thereof, wherein R1, R2, R3, and R4 are as described in the specifica... | 09/27/2005 |
| 6949630 | Cationic reactive dyes The cationic dyes of formula (1) specified in claim 1 are suitable especially for colouring keratin-containing fibres, more especially for colouring hair. ... | 09/27/2005 |
| 6943249 | Methods for isolating crystalline Form I of 5-azacytidine The invention includes methods for isolating crystalline Form I of 5-azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compos... | 09/13/2005 |
| 6919090 | Active substance combinations with insecticidal and acaricidal properties The invention relates to novel active combinations of certain cyclic ketoenols and certain active compounds that together have unexpectedly good insecticidal and acaricidal properties. ... | 07/19/2005 |
| 6903132 | Non-peptide GnRH agents, pharmaceutical compositions and methods for their use Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and ster... | 06/07/2005 |
| 6894047 | Triazine compounds useful as sorbitol dehydrogenase inhibitors This invention is directed to sorbitol dehydrogenase inhibitory compounds of formula I wherein R1, R2 and R3 are as defined in the specification. This invention is also directed to phar... | 05/17/2005 |
| 6887870 | Heterocyclic sodium/proton exchange inhibitors and method Heterocyclic are provided which are sodium/proton exchange (NHE) inhibitors which have the structure wherein n is 1 to 5; X is N or C—R5 wherein R5 is H, halo, alkenyl, alkynyl, alkoxy, alkyl, a... | 05/03/2005 |
| 6887831 | Substituted thienyl(amino)sulfonylureas The invention relates to novel substituted thienyl(amino)sulphonylureas of the general formula (I) in which A, Q, R1, R2, R3, R4 and R5 are each as defined in the ... | 05/03/2005 |
| 6884804 | Inhibitors of Src and other protein kinases The present invention provides compounds of formula I: wherein A is N or CR, and G, R1, R2 and R3 are as described in the specification. These compounds are inhibitors of protein kinase... | 04/26/2005 |
| 6881737 | Substituted triazinyl acrylamide derivatives and methods of use The invention encompasses compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions, uses and methods for prophylaxis and treatment of cancer and polycystic kidney disease. ... | 04/19/2005 |
| 6870052 | Preparation of thioarabinofuranosyl compounds and use thereof Patients suffering from cancer are treated by being administered a compound represented by the following formula: wherein each R individually is H or an aliphatic or aromatic acyl group; ... | 03/22/2005 |
