Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 8106194 | Pyrrolopyrimidine and pyrrolotriazine derivatives An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disea... | 01/31/2012 |
| 7300910 | Lubricating oil composition Lubricating oil compositions providing superior soot dispersing characteristics, which contain a combination of a high molecular weight dispersant and a soot dispersant comprising a linked aromatic oligomer. ... | 11/27/2007 |
| 7285550 | Triazolotriazines and pyrazolotriazines and methods of making and using the same The invention is based on the discovery that compounds of formula (I) possess unexpectedly high affinity for the A2a adenosine receptor, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including Parkinson's disea... | 10/23/2007 |
| 7226246 | Apparatus and method for building support piers from one or successive lifts formed in a soil matrix An apparatus and method for forming a support pier having a single or multiple compacted aggregate lifts in a soil matrix, wherein the apparatus includes a vertical, hollow tube with a bulbous leading end or head element that is forced into the soil matrix. The holl... | 06/05/2007 |
| 7189848 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation The present invention relates to a compound of the formula (I) The compound according to the invention is suitable for the preparation of herbicidal active substances such as sulfonylureas. ... | 03/13/2007 |
| 7183409 | Basic mono- and bisazo compounds The invention relates to basic mono- and bisazo compounds according to formula (I) wherein all substituents are defined as in Claim 1, their production, their use as dyestuffs as well as material dyed with these ... | 02/27/2007 |
| 7109329 | Neurologically active compounds and compounds with multiple activities This invention provides pharmacologically active compounds having neurological and other bio-active capability. These active compounds comprise the derivatives of guanidino, aminoguanidino, 2-imadazolino, 2-hydrazinoimidazolino or 2-guanidinobenzimidazolino groups. | 09/19/2006 |
| 7087753 | Naphthyltriazines as stabilizers for organic material Novel compounds of formula I are described wherein E corresponds to the formula or to the formula ... | 08/08/2006 |
| 7057043 | Processes for preparing aminophenylsulfonylureas, and intermediates therefor The invention relates to the preparation of compounds (I) in which A=H or acyl and R1, R2, R3, R, n, X, Y and Z are as defined in claim 1 by halogenation and rearrangement ... | 06/06/2006 |
| 7002011 | Process for the preparation of 2-amino-4-chloro-1,3,5-triazines Compounds of the formula (I) or salts thereof are suitable for preparing active substances from the from the class of the aminotriazines of the formula (IV), for example herbicidal active substances. The compounds (I) c... | 02/21/2006 |
| 6974497 | Monoazo dyes Claimed are compounds of formula (I) where the substituents are each as defined in the claims, their preparation, their use as dyes and as a ingredients of an ink-jet printing ink and also substrates dyed with such compounds. | 12/13/2005 |
| 6906067 | N-heterocyclic inhibitors of TNF-α expression N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutica... | 06/14/2005 |
| 6881737 | Substituted triazinyl acrylamide derivatives and methods of use The invention encompasses compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions, uses and methods for prophylaxis and treatment of cancer and polycystic kidney disease. ... | 04/19/2005 |
| 6864255 | Substituted triazinyl amide derivatives and methods of use The invention encompasses compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions, uses and methods for prophylaxis and treatment of cancer and angiogenesis-related disease. ... | 03/08/2005 |
| 6861389 | Substituted 2-amino-1,3,5-triazines, their preparation, and their use as herbicides and plant growth regulators The compounds of the formula (I) and their salts where the radicals R1 to R4, A1, A2, L0, X and n are as defined in claim 1 are suitable as herbicides and plant gr... | 03/01/2005 |
| 6858609 | Substituted diamino-1,3,5-triazine derivatives This invention concerns the compounds of formula the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein R1 and R2 are each independently selecte... | 02/22/2005 |
| 6852717 | Compounds useful as anti-inflammatory agents Disclosed are compounds useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds. ... | 02/08/2005 |
| 6806268 | Method for treating glaucoma V Provided, among things, is a method of decreasing intraocular pressure in an animal, including a human, comprising administering an intraocular pressure decreasing amount of a compound of the formula IA and or IB: ... | 10/19/2004 |
| 6800757 | Red-shifted triazine ultravioletlight absorbers The present invention relates to novel red-shifted UV absorbers comprising 1,3,5-triazine structures containing a 2-naphthol-derived substituent. The present invention also relates to a method for stabilizing a material by incorporating into such material, e.g., org... | 10/05/2004 |
| 6790943 | Reactive dye compounds A reactive dye compound comprising: (a) at least one chromophore moiety; (b) at least one SO2C2H4 group which is attached to the chromophore moiety either directly via the sulphur atom of the SO2C2... | 09/14/2004 |
| 6761758 | Alkylated tetrakis(triaminotriazine) compounds and phase change inks containing same Disclosed are compounds of the formulae wherein, provided that at least one of R1, R2, R3, R4, R5, and R6 is a hydrogen atom, and provided that at least o... | 07/13/2004 |
| 6743817 | Substituted fused pyrroleimines and pyrazoleimines Disclosed are compounds of the formula and the pharmaceutically acceptable salts thereof wherein R, Ar, A, n, R1 and R2 are defined herein. These compounds are highly selective agonists, antagonists... | 06/01/2004 |
| 6723834 | Reactive dye compounds A reactive dye compound comprising: (a) at least one chromophore moiety; (b) at least one nitrogen-containing heterocycle (c) a linking group to link each chromophore moiety to each nitrogen-containing heterocycle; characterized in that a... | 04/20/2004 |
| 6713613 | Reactive dye compounds A reactive dye compound comprising: (a) at least one chromophore moiety (b) at least one nitrogen-containing heterocycle (c) a linking group to link each chromophore moiety to each nitrogen-containing heterocycle; characterised in that at... | 03/30/2004 |
| 6677341 | (R)-Chiral halogenated substituted heteroaryl benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and m... | 01/13/2004 |
| 6630470 | G-CSF mimetics Invented are G-CSF mimetics. Also invented are selected octacyclic compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds as G-CSF mimetics. Also invented are novel processes used in preparing these compoun... | 10/07/2003 |
| 6610846 | Heteroaromatic glucokinase activators 2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 3-position being a substituted phenyl group and at the 2-position being a methyl cycloalkyl ring, said propionamides being glucokinase activators which increase insulin secret... | 08/26/2003 |
| 6586433 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 07/01/2003 |
| 6555539 | Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation Indazole compounds that modulate and/or inhibit cell proliferation, such as the activity of protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating, e.g., kinases-dependent diseases to modula... | 04/29/2003 |
| 6509338 | Pyrazolo[1,5-A]triazine corticotropin releasing factor antagonists The present invention describes novel pyrazolo[1,5-a]triazines of formula: ##STR1## wherein R3 is an alkyl, alkenyl, alkynyl, or cycloalkyl group, or pharmaceutically acceptable salt forms thereof, which are useful as CRF antagonists.... | 01/21/2003 |
| 6482829 | Substituted heterocyclic siprodecane compound active as an antagonist of neurokinin 1 receptor The invention relates to compounds of the formula ##STR1## as described herein and pharmaceutically acceptable acid addition salts thereof. The described compounds have a good affinity to the NK1 receptor.... | 11/19/2002 |
| 6451737 | Substituted aryl sulphonyl (thio) ureas as herbicides The invention related to novel substituted arylsulphonyl(thio)ureas ##STR1## wherein: A is nitrogen or a CH grouping, Q is oxygen or sulphur, R1 is hydrogen, halogen or optionally substituted alkyl, alkoxy, alkylthio, alkylamino, dialkylamino, ... | 09/17/2002 |
| 6413911 | Herbicidal sulfonylureas, their preparation and use Sulfonylureas of the general formula I ##STR1## where R1 is a methyl or ethyl group; R2 is C1 -C3 -alkoxycarbonyl, a C1 -C2 -alkyl group which carries 1 to 5 fluorine atoms, methylsulfonyl, ... | 07/02/2002 |
| 6380194 | Substituted diamino-1,3,5-triazine derivatives This invention concerns the compounds of formula ##STR1## the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein R1 and R2 are each independently selected from hydrogen; hydroxy; ... | 04/30/2002 |
| 6372743 | Certain alkylene diamine-substituted pyrazlo (1,5-a)-1,5-pyrimidines and pyrazolo (1,5-a) 1,3,5-triazines Disclosed are compounds of the formula: ##STR1## where R1, R2, R3, R4, R5, R6, and X are defined herein. These compounds are selective modulators of NPY1 receptors. These compounds are usef... | 04/16/2002 |
| 6358950 | Azolo triazines and pyrimidines Corticotropin releasing factor (CRF) antagonists of formula I or II: ##STR1## and their use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart-related diseases and ... | 03/19/2002 |
| 6350872 | Salt free dyeing of cellulosic fibers with anionic dyes Quaternary ammonium compounds having at least two fiber reactive sites and at least two dye reactive sites, and processes for making and using the same are disclosed. The compounds of the invention can advantageously be used in a cellulosic fabric pretrea... | 02/26/2002 |
| 6346531 | G-CSF mimetics Invented are G-CSF mimetics. Also invented are selected octacyclic compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds as G-CSF mimetics. Also invented are novel processes used in preparing these compoun... | 02/12/2002 |
| 6329373 | Metalloproteinase inhibitors A compound of formula (I) ##STR1## wherein X is a --CONHOH group and the R groups are defined in the claims. The compounds are inhibitors of matrix metalloproteinases involved in tissue degradation and inhibitors of the release of tumour necrosis factor ... | 12/11/2001 |
| 6326368 | Aryloxy- and arylthiosubstituted pyrimidines and triazines and derivatives thereof The present invention provides novel compounds, and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsey, irrita... | 12/04/2001 |
