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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 8110682 | Preparation and use of compounds as aspartyl protease inhibitors Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein A is a bond, —C(O)—, or —C(R3′ | 02/07/2012 |
| 7994316 | 1,3,5-triazine derivative, production method thereof and organic electroluminescence device comprising this as a composing component Since the conventional electron transporters have low thermal stability, the organic electroluminescent devices using them are not sufficient in terms of the compatibility of their luminance and luminous efficiency with device lifetime. A 1,3,5-triazine deriv... | 08/09/2011 |
| 7947831 | Sulfoxides or sulfones grafted onto polymers Polymers grafted with a compound of formula I, wherein the general symbols are as defined within, have outstanding stability against oxidative, thermal, dynamic, light-induced and/or ozone-induced degradation. ... | 05/24/2011 |
| 7851622 | Non-basic melanin concentrating hormone receptor-1 antagonists The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I. Additionally, the present application provides pharmaceutical compositions containing at least one compo... | 12/14/2010 |
| 7842805 | Pharmaceutical compounds as activators of caspases and inducers of apoptosis and the use thereof Disclosed are 1-arylamino-phthalazines, 4-arylamino-benzo[d][1,2,3]triazines, and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which ... | 11/30/2010 |
| 7732598 | Triazine-based compound, method of making the same, and an organic light-emitting device including the same A triazine-based compound having three biphenyl groups, represented by Structure 1, below, wherein R1 through R18 are each independently one of: hydrogen, a substituted C1-30 alkyl group, an unsubstituted C1-30 alkyl group... | 06/08/2010 |
| 7678905 | Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzym... | 03/16/2010 |
| 7579465 | Antiviral agents This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infect... | 08/25/2009 |
| 7504501 | Antiprotozoal imidazopyridine compounds Compounds described by the Formula (I): (I) or pharmaceutically acceptable salts, or N-oxides thereof. The compounds are useful for the treatment and prevention of protozoal diseases in mammals and birds. A method for controlling coccidiosis in poultry comprises adm... | 03/17/2009 |
| 7449574 | Triazine based photoactive compound containing oxime ester The present invention relates to a triazine based photoactive compound containing an oxime ester group. The compound according to the present invention is a photoactive compound containing both an oxime ester group and a triazine group in one molecule, has ex... | 11/11/2008 |
| 7442792 | Process for the preparation of pyrazolo[1,5-a]-1,3,5-triazines and intermediates thereof The present invention provides novel processes and intermediates for preparing corticotropin releasing factor (CRF) receptor antagonists having the structure below which are useful in treating CRF-related disorders such as anxiety and depression. ... | 10/28/2008 |
| 7429590 | Antiprotozoal imidazopyridine compounds Compounds described by the Formula (I) or (II): or pharmaceutically acceptable salts, or N-oxides thereof. The compounds are useful for the treatment and prevention of protozoal diseases in mammals and birds. A method for controlling coccidiosis in poultry comprises... | 09/30/2008 |
| 7425629 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols A process for stereoselective synthesis of a compound of Formula (I) wherein R1, R2, R3, R4, and R5 are as described herein. ... | 09/16/2008 |
| 7414011 | Phenylsulfonyl ureas, process for their preparation and their use as herbicides and plant growth regulators Disclosed are compounds of the formula (I) or salts thereof in which R1, R2, R3, R4, I, R5, Q, R4, W, X, Y, V and Z, are as defined in the specification, whi... | 08/19/2008 |
| 7407976 | Thiazoles and oxazoles useful as modulators of ATP-Binding Cassette transporters The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to meth... | 08/05/2008 |
| 7407962 | Heteroaryl compounds useful as inhibitors or protein kinases The present invention provides compounds that are inhibitors of protein kinase, particularly inhibitors of ERK2, GSK3, PKA, CDK2 protein kinases, mammalian protein kinases involved in proliferative and neurodegenerative disorders. The invention also provides pharmac... | 08/05/2008 |
| 7405217 | N-aroyl piperazine derivatives as orexin receptor antagonists This invention relates to N-aroyl cyclic amino derivatives and their use as pharmaceuticals. ... | 07/29/2008 |
| 7405296 | Additives for fluorinated oils Compounds of formula wherein Rf is a (per)fluoropolyoxyalkylene chain having a number average molecular weight in the range 500-10,000; W1, W2 | 07/29/2008 |
| 7388019 | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes The present invention is directed to 3-amino-4-phenylbutanoic acid derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV en... | 06/17/2008 |
| 7358244 | Azabicycloalkane compounds This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, or a pharmaceutically acc... | 04/15/2008 |
| 7348335 | Compositions useful as inhibitors of JAK and other protein kinases The present invention provides a compound of formula I: or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and metho... | 03/25/2008 |
| 7329757 | Substituted iminoazines The invention relates to novel substituted iminoazines of the general formula (I) in which R1, R2, R3, R4, Z1, Z2 and Z3 a... | 02/12/2008 |
| 7326706 | Pyrazine modulators of cannabinoid receptors The present application describes compounds according to Formula I, wherein A, G1, G2 and R1 are described herein. Additionally, the present application describes pharmaceutical compositions comprising at least one compound according... | 02/05/2008 |
| 7319131 | Phenolic resins The invention herein disclosed comprises the use of oxazolidines, nitroalcohols, nitrones, halonitroparaffins, oxazines, azaadamantanes, hexamethylenetetramine salts, nitroamines, imidazolidines, triazines, nitrooxazolidines, and imidazolidine-oxazolidine hybrids to... | 01/15/2008 |
| 7317122 | Curable trans-1,2-cyclohexane bis(urea-urethane) compounds Curable trans-1,2-cyclohexane bis(urea-urethane) compounds of the formulae wherein R1 and R′1 each, independently of the other, are alkylene, arylene, arylalkylene, or alkylarylene groups,... | 01/08/2008 |
| 7314949 | Trans-1,2-cyclohexane bis(urea-urethane) compounds Disclosed are trans-1,2-cyclohexane bis(urea-urethane) compounds of the formulae wherein R1 and R′1 each, independently of the other, is an alkylene group, an arylene group, an arylalkylen... | 01/01/2008 |
| 7311897 | Symmetrical triazine derivatives Disclosed is the use of the compounds of formula wherein A is a radical of formula R1 and R5 independentl... | 12/25/2007 |
| 7312227 | Compositions useful as inhibitors of JAK and other protein kinases The present invention provides a compound of formula I: or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the inventio... | 12/25/2007 |
| 7301028 | Mitotic kinesin inhibitors The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which com... | 11/27/2007 |
| 7294287 | Quinophenanthrine diones fluorescent whitening agents Tetrahydro- and dihydroquinophenanthrine dione fluorescent whitening agents and a process for their preparation are provided. ... | 11/13/2007 |
| 7265171 | Transparent polymer articles of low thickness The novel transparent polyolefin, polyester or polyamide article disclosed is stabilized against the effects of light, oxygen, heat and agressive chemicals by addition of 0.005-0.30% by weight the polymeric substrate of a hydroxyphenyl triazine UV absorber, and is c... | 09/04/2007 |
| 7261743 | Dicationic compounds for dyeing human keratin fibers, and compositions comprising them The present disclosure relates to the process of dyeing human keratinous fibers, such as the hair, with at least one specific direct dye in cosmetic compositions. Also disclosed herein are the direct dyeing and lightening compositions comprising said compounds, and ... | 08/28/2007 |
| 7259163 | 4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as HCV inhibitors Novel anti-viral agents of Formula wherein: A represents OR1, NR1R2, or R1 wherein R1 and R2 are hydrogen, C1-6alkyl, aryl... | 08/21/2007 |
| 7256287 | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. This invention also relates to phenyl-aza-benzimidazole molecules tha... | 08/14/2007 |
| 7235560 | Pyrimidine derivative as selective COX-2 inhibitors The invention provides the compounds of formula (I) or a pharmaceutically acceptable salt thereof. Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the treatment of ... | 06/26/2007 |
| 7232467 | Method of coloring porous material A method of colouring porous material, especially human hair, is described, which method comprises applying to the material being coloured, in any desired order successively, or simultaneously, a) at least one capped diazonium compound of Formula (1) and/or at least... | 06/19/2007 |
| 7229479 | Method of coloring porous material A method of coloring porous material, especially human hair, is described, which method comprises applying to the material being colored, in any desired order successively, or simultaneously, a) at least one capped diazonium compound and b) at least one cationic wat... | 06/12/2007 |
| 7230139 | Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid... | 06/12/2007 |
| 7226927 | Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators of caspases and inducers of apoptosis and the use thereof The present invention is directed to substituted 2-aryl-4-arylaminopyrimidine and analogs thereof, represented by the general Formula I: wherein A, Ar1, Ar2, R1 and R3 ... | 06/05/2007 |
| 7220300 | Phase change inks containing bis(urea-urethane) compounds Disclosed is a phase change ink composition comprising a phase change ink carrier and a bis(urea-urethane) compound of the formula wherein R1 and R1′ each, independently of the other, is a... | 05/22/2007 |
