Quotables
"It is my heart-warmed and world-embracing Christmas hope and aspiration that all of us, the high, the low, the rich, the poor, the admired, the despised, the loved, the hated, the civilized, the savage (every man and brother of us all throughout the whole earth), may eventually be gathered together in a heaven of everlasting rest and peace and bliss, except the inventor of the telephone. "
Mark Twain ; Christmas greetings, 1890
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7435851 | Puleganic amides The present invention provides substituted puleganic amides and compositions thereof, which are both useful as a topical treatment for skin, such as a repellant for insects and arthropods. ... | 10/14/2008 |
| 7232821 | (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein A, R1, R2, Rx, R8, R9 and n are as defined in the specification, a proc... | 06/19/2007 |
| 7195751 | Compositions and kits pertaining to analyte determination This invention pertains to methods, mixtures, kits and/or compositions for the determination of analytes by mass analysis using unique labeling reagents or sets of unique labeling reagents. The labeling reagents can be isomeric or isobaric and can be used to produce... | 03/27/2007 |
| 7034020 | Derivatives of butyric acid and uses thereof The present invention provides a series of compounds having structural formulas wherein n1 is 1 to 5, n2 is 1 to 4 and m is 1 to 3; X is O or NH; Y is CH2, O, S, NH, NR; R is selected from the grou... | 04/25/2006 |
| 7002010 | Process for the preparation of morpholinones as light stabilizers The instant invention discloses a process for the preparation of compounds of the formula I: wherein the general symbols are as defined in claim 1, which process comprises reacting a compound of formula II: | 02/21/2006 |
| 6803370 | Alpha amino acid derivatives—inhibitors of leukocyte adhesion mediated by VLA-4 Disclosed are certain alpha amino acid compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian... | 10/12/2004 |
| 6689882 | Process for the synthesis of morpholinylbenzenes A new improved process for synthesizing morpholinylbenzenes of the formula I by reacting morpholine of formula II with a substituted benzene of formula III, wherein morpholine is used as a reactant and as the only one solvent. ##STR1##... | 02/10/2004 |
| 6602869 | Compounds derived from benzoic acid esters, composition containing said compounds and use thereof This invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 represents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR | 08/05/2003 |
| 6479491 | Disubstituted morpholine, oxazepine or thiazepine derivatives, their preparation and their use as dopamine d4 receptor antagonists The present invention relates to compounds of formula (I), any of it enantiomers, or any mixture thereof, or a pharmaceutically acceptable acid addition salt thereof, wherein R1, R2, R3, R4, R11, R | 11/12/2002 |
| 6479518 | Zwitterionic tachykinin receptor antagonists The present invention is directed to certain novel compounds represented by structural formula I: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R3, R5, R6, R7, R8, R11, R | 11/12/2002 |
| 6200972 | Heterocyclic esters and amides This invention relates to neurotrophic low molecular weight, small molecule heterocyclic esters and amides having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particular... | 03/13/2001 |
| 6093823 | Process for the continuous production of basic cyclic optically active - amino acids The invention pertains to a process for the continuous production of basic cyclic optically active -amino acids of general formula (I) by continuous racemate splitting via diastereomeric salt pairs with re-racemisation of the residual amino acid or... | 07/25/2000 |
| 6037498 | Chiral syntheses This invention relates to novel compounds of general formula (I) ##STR1## wherein R1 represents an organic group, R2 represents a hydrogen atom or an organic group, and the asterisk denotes that the group R1 is predom... | 03/14/2000 |
| 5955608 | Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents Novel processes for producing benzothiophenes employing ethylene carbonate or propylene carbonate are provided.... | 09/21/1999 |
| 5917086 | Purification process A method for the purification of a keto acid having the general formula ##STR1## wherein R1 and R2 independently represent a straight or branched chain alkyl of 1-18 carbon atoms, a cycloalkyl of 4-8 carbon atoms or a phenyl both of which may be subs... | 06/29/1999 |
| 5885984 | Aminocyclohexylesters and uses thereof Aminocyclohexylester compounds, including thioesters, are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and com... | 03/23/1999 |
| 5869663 | Substituted heterocyclic compounds The invention relates to compounds of the formula ##STR1## in which: A is a divalent radical selected from: A1) --O--CO-- A2) --CH2 --O--CO-- A3) --O--CH2 --CO-- A4) --O--CH2 --CH | 02/09/1999 |
| 5852193 | Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceuticals The invention relates to intermediates and processes for producing benzothiophenes employing hydroxylamines.... | 12/22/1998 |
| 5783697 | Preparation of vinyl carbamates Vinyl carbamate compounds are prepared by reacting appropriate secondary amines with carbon dioxide and acetylenically unsaturated compounds in the presence of a compound of a metal from the platinum group, in particular a ruthenium compound, with either ... | 07/21/1998 |
| 5756817 | O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same The present invention relates to a racemic or enantiomerically enriched O-carbamoyl-phenylalaninol compound represented by the following structural formula V and pharmaceutically acceptable salts thereof to treat diseases of the central nervous system: ... | 05/26/1998 |
| 5731436 | Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents Processes for producing benzothiophenes employing ethylene carbonate or propylene carbonate are provided.... | 03/24/1998 |
| 5716624 | Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (1): ##STR1## in which X is one of the radicals: ##STR2## and are useful for the treatment of a wide variety of disease states, whether h... | 02/10/1998 |
| 5686586 | Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same A polycyclic aromatic compound having the formula ##STR1## and its salts have useful therapeutic and cosmetic action particularly in psoriasis. In the formula, X represents --CH.dbd.CH--, O or S, R1 represents hydrogen, branched alkyl having 3-... | 11/11/1997 |
| 5686623 | Method for preparing taxane derivatives A method for preparing taxane derivatives of general formula (I) by esterifying protected baccatin III or protected 10-deacetyl baccatin III with an acid of general formula (II). In general formulae (I) and (II), Ar is an aryl radical; R1 and R... | 11/11/1997 |
| 5631369 | Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents Novel processes for producing compounds of formula I ##STR1## wherein R1 and R2 each are independently C1 -C4 alkyl, or combine to form piperidinyl, pyrrolidinyl, methylpyrrolidinyl, dimethylpyrrolidinyl, m... | 05/20/1997 |
| 5552543 | Six-membered hetero "N" compounds Novel six-membered hetero "N" compounds having antibiotic activity, represented by the formula: ##STR1## where X.dbd.S, O, CH2, or Se Y.dbd.OH, NH2, NHCOR9, or SH R1,R2,R3,R4,R | 09/03/1996 |
| 5547983 | Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics Aromatic bicyclic compounds of formula (I) ##STR1## where R.sub.1 is specifically --H, CH.sub.3, --CH.sub.2 OH, --OH, --CHO, --CONH.sub.2, --COOH, --COOalkyl, --SH, S-alkyl, etc. . . . ; R.sub.2 is H; R.sub.3 is H, aryl, aralkyl or lower alkyl option... | 08/20/1996 |
| 5512565 | Cholesterol ester hydrolase inhibitors The compounds of the formula: ##STR1## in which ##STR2## where R7 is hydrogen, alkyl, hydroxy, alkanoyloxy, hydroxyalkyl, hydroxycarbonyl, alkoxycarbonyl, phenyl or substituted phenyl, in which the substituent is alkyl, alkoxy, h... | 04/30/1996 |
| 5385917 | Carboxylic acid derivatives Carboxylic acid derivatives of the formula: ##STR1## are provided, which are useful for treatment of androgen dependent diseases.... | 01/31/1995 |
| 5373009 | Dibenzofuranyl esters of N-heterocyclic carboxylic acids A compound of the formula: ##STR1## wherein R1 and R2 are, independently, halo, trifluoromethyl, cyano, nitro, alkyl, alkoxy, --CO2 H, alkylcarbonyl, alkylcarbonyloxy, alkoxycarbonyl, mono- or di-alkylaminocarbonyl, o... | 12/13/1994 |
| 5336684 | Oxidation products of cephalomannine Antineoplastic taxol derivatives are derived by selective oxidation of the alkene portion of the side chain of cephalomannine. The derivative displays high activity in promoting assembly of microtubulin and also displays cytotoxic activity against maligna... | 08/09/1994 |
| 5321139 | Process for the enantioselective synthesis of 2(R)-benzylsuccinic acid monoamide derivatives Two processes are described for the preparation of the optically pure compounds of formula 1: ##STR1## in which R1 and R2 are e.g. alkyl, R3 and R4 are e.g. hydrogen and R5 is e.g. hydrogen. Both... | 06/14/1994 |
| 5298649 | Naphthalene derivative A naphthalene derivative having the formula is new and useful for medicine. ##STR1## wherein R1 represents a hydrogen atom, a lower alkyl group or an acyl group; R2 independently represents a hydrogen atom, a lower alkyl group, a ... | 03/29/1994 |
| 5281720 | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, ... | 01/25/1994 |
| 5190940 | Cholesterol ester hydrolase inhibitors The compounds of the formula: ##STR1## in which R1 is hydrogen or alkyl; R2 is alkyl, cycloalkyl, cycloalkylalkyl, phenylalkyl or alkylphenylalkyl; or R1 and R2 taken together complete a heterocyclic moiety... | 03/02/1993 |
| 5183889 | Benzonaphtahalene derivatives, a process for their preparation and their use in therapeutic and cosmetic compositions A benzonphthalene compound has the formula ##STR1## wherein R1 represents ##STR2## or (ii) --CH2 OH; R6 represents ##STR3## or OR7 wherein R7 represents hydrogen, alkyl having 1-20 carb... | 02/02/1993 |
| 5173487 | Mevinic acid derivatives Antihypercholesterolemic activity, due to competitive inhibition of HMG CoA reductase, is exhibited by a compound of the formula ##STR1## m is 0 to 3; R is selected from: (1) alkyl; (2) substituted alkyl; (3) alkoxy; (4) alkenyl; (5) cycloalkyl; (6) pheny... | 12/22/1992 |
| 5162571 | Phenol derivatives, their production and use Novel phenol derivatives of the general formula: ##STR1## wherein R1, R2, R3, R4, R5, X, Y and n are as defined in the specification, which have therapeutic and prophylactic activities against ce... | 11/10/1992 |
| 5145958 | Process for the preparation of 2,4- or 2,6-dihalogeno-aniline 2,4- or 2,6-dihalogeno-aniline can be prepared by reacting an amino-benzoic acid ester of the formula ##STR1## in which R1, R2 and R3 have the meanings indicated in the description, with 2-2.5 moles of a chlorinating ... | 09/08/1992 |
| 5142048 | Intermediate for preparation of amino acid derivatives The invention relates to novel intermediate compounds for preparation of novel amino acid derivatives having renin inhibiting activity.... | 08/25/1992 |
