Pizza Pie With Concentric Rings of Crust
A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.
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| Number | Title | Issue Date |
| 8067586 | Fused heteroaryl derivatives The present invention provides a pharmaceutical composition which is useful as a phosphatidylinositol 3 kinase (PI3K) inhibitor and an antitumor agent, and it provides a novel bicyclic or tricyclic fused heteroaryl derivative or a salt thereof which possesses an exc... | 11/29/2011 |
| 7825242 | Dipeptidyl peptidase inhibitors Compounds, pharmaceutical compositions, kits and methods are provided for use with DPP-IV and other S9 proteases that comprise a compound of the formula: wherein R2 is amino (C1-6)alkyl, hetero(C3... | 11/02/2010 |
| 7439240 | Purine-or pyrrolol[2,3-d]pyrimidine-2-carbonitiles for treating diseases associated with cysteine protease activity The present invention therefore provides a compound of formula (I) and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases ... | 10/21/2008 |
| 7429596 | 1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof This invention generally relates to pyrazolo pyrimidine derivatives useful as inhibitors of short chain dehydrogenase/reductase (SDR) family of NAD(P)(H) dependent oxido-reductases. The invention further relates to pharmaceutical compositions and methods of preventi... | 09/30/2008 |
| 7427616 | Condensed pyridines and pyrimidines with tie2 (TEK) activity A compound of the Formula (I), wherein A together with the carbon atoms to which it is attached forms a fused 5-membered heteroaryl ring, wherein said heteroaryl ring contains 1 or 2 heteroatoms selected from O, N and S, and wherein the 5-membered ring containing G ... | 09/23/2008 |
| 7410967 | Pyridodiazines as plant fungicides Fungicidal compounds of general formula (1) wherein R, R1, R2, W, X, Y and Z are as defined in the specification ... | 08/12/2008 |
| 7410966 | Use of and some novel imidazopyridines The use of compounds of formula (I) wherein R1, R3, R10, m and Ar are as defined in the Specification and pharmaceutically acceptable salts thereof in the manufacture of a medicament for the treatment or prophylaxis of diseases or co... | 08/12/2008 |
| 7405295 | Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds Compounds of Formula I-a and all pharmaceutically-acceptable forms thereof, are described herein. The variables R1, R2, R3, Z1, Q, and A shown in Formula I-a are defined h... | 07/29/2008 |
| 7390805 | 4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives The invention relates to 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula I wherein the symbols and substituents are as defined in the description, to processes for the preparation thereof, to pharmaceutical compositions ... | 06/24/2008 |
| 7378423 | Pyrimidine compound and medical use thereof The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeuti... | 05/27/2008 |
| 7378411 | Substituted thienopyrimidinones as a mitotic kinesin inhibitor The present invention relates to thienopyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which ... | 05/27/2008 |
| 7378417 | Pyrazolo-pyrimidine derivatives The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5 and p are as defined in the description and to pharmaceutically acceptable salts thereof, t... | 05/27/2008 |
| 7368471 | Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) This invention provides compounds of the formula: wherein: X is a chemical bond, —CH2— or —C(O)—; R1 is alkyl, cycloalkyl, —CH2-cycloalkyl, pyridinyl, —CH2-pyridinyl, ... | 05/06/2008 |
| 7361662 | Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same A compound of formula (I): wherein: R1, R2, R3, R4 are defined in the description, its enantiomers, diastereoisomers, tautomers and also addition salts thereof with a phar... | 04/22/2008 |
| 7358250 | Pyrrolo[2,3-d]pyrimidines that modulate ACK1 activity Compounds that modulate the action of ACK1 and LCK, and related compositions methods for treating ACK1- and LCK-mediated diseases are described. In one aspect, the compounds have the general structure: where the values of t... | 04/15/2008 |
| 7351726 | Substituted oxadiazolidinediones The present invention relates generally to substituted oxadiazolidinediones and methods of using them. ... | 04/01/2008 |
| 7351730 | Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1) This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R1, R2, R3, and R4 are each H, alkyl, alkanoyl, halo, OH, aryl optionally substituted with R8,... | 04/01/2008 |
| 7348351 | Substituted 3-alkyl and 3-arylalkyl -indol-1yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) The invention formula substituted 3-alkyl and 3-arylalkyl 1H indol-1yl acetic acid derivatives which are useful as inhibitors of plasminogen activator inhibitor (PAI-1) useful for treating fibrinolytic disorders, the compounds having the structure ... | 03/25/2008 |
| 7342012 | Inhibitors of αβmediated cell adhesion The present invention relates to a compound of the following formula: or a pharmaceutically acceptable salt thereof. Also disclosed are compositions containing the compound and methods of preparing and using the compounds. ... | 03/11/2008 |
| 7342039 | Substituted indole oximes The present invention relates to substituted indole oximes and methods of using them. ... | 03/11/2008 |
| 7332521 | Substituted indoles The present invention relates generally to substituted indoles such as substituted 1H-indole-2-carboxylic acid derivatives, and methods of using them. ... | 02/19/2008 |
| 7329659 | Substituted-1-phthalazinamines as vr-1 antagonists The present invention provides a compound of formula (I): in which Ar and R1 are phenyl or a heteroaromatic group, R2 is generally hydrogen, R3 is hydrogen or alkyl and X, Y and Z are generally CH or N as VR-1 antagonists; or a pharm... | 02/12/2008 |
| 7326699 | 4-Amino-5-phenyl-7-cyclobutyl-pyrrolo(2,3-d)pyrimidine derivatives The invention relates to new 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives, processes for the preparation thereof, the application thereof in a process for the treatment of the human or animal body, the use thereof-alone or in combination with o... | 02/05/2008 |
| 7323468 | Pyridopyrazines and the use thereof as kinase inhibitors The invention relates to novel pyrido[2,3-b]pyrazine derivatives of the general Formula I, their preparation and use as medicaments, in particular for the treatment of malignant and other disorders based on pathological cell proliferations. | 01/29/2008 |
| 7317006 | Thieno[2,3-]pyrimidines with combined LH and FSH agonistic activity The invention relates to thieno[2,3-d]pyrimidine derivatives according to general formula I, or a pharmaceutically acceptable salt thereof, wherein N(R1)R2 are joined in a (2-6C)heterocycloalkyl ring. The compoun... | 01/08/2008 |
| 7314873 | (Halo-benzo carbonyl)heterobi cyclic p38 linase inhibiting agents Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: (I) are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty ar... | 01/01/2008 |
| 7294633 | Oxazolo-and furopyrimidines and their use in medicaments against tumors The invention relates to pharmaceutically acceptable compounds of formula I, wherein the radicals have the significances given in the description. Compounds of formula I are useful against tumor diseases ... | 11/13/2007 |
| 7279474 | Substituted pyrrolo[2,3-d]pyrimidines as antagonists of the corticotropin releasing factor (CRF) The present invention provides compounds of formula (I) including stereoisomers, prodrugs and pharmaceutically acceptable salts or solvates thereof wherein the variables are as defined in the description, processes for their preparation, pharmaceutical compositions ... | 10/09/2007 |
| 7268159 | Substituted indoles The present invention relates generally to substituted indoles and methods of using them. ... | 09/11/2007 |
| 7265148 | Substituted pyrrole-indoles The present invention relates generally to substituted pyrrole-indoles such as substituted pyrrole-indoles, and methods of using them. ... | 09/04/2007 |
| 7262186 | Substituted pyrazolo[3,4-d] pyrimidinones as a mitotic kinesin inhibitor The present invention relates to azolopyriniidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which ... | 08/28/2007 |
| 7262187 | Substituted oxazolo- and thizaolopyrimidinones as a mitotic kinesin inhibitor The present invention relates to azolopyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which c... | 08/28/2007 |
| 7259154 | Pyrrolopyrimidines Compounds of the formula and N-oxides, prodrugs, acid bioisosteres, pharmaceutically acceptable salts or solvates of such compounds, or N-oxides, prodrugs, or acid bioisosteres of such salts or solvates, to compo... | 08/21/2007 |
| 7259182 | Aryl, aryloxy, and aklyloxy substituted 1-indol-3-yl glyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) Compounds of formula I are provided: wherein: R1, R2, and R3, are as defined herein, as well as pharmaceutical composition and methods using the compounds as inhibitors of plasminogen activator inhibitor ... | 08/21/2007 |
| 7253284 | Chemical compounds Compounds of the formula I, Wherein X is N, n is 1 and R2and R3 together form a ring, R, R1 and R4 are as defined in the specifications. ... | 08/07/2007 |
| 7253166 | 6-phenyl-7H-pyrrolo[2,3-d]pyrimidine compounds that induce neuronal differentiation in embryonic stem cells The invention provides a novel class of compounds and compositions of Formula I: in which R1, R2 and R3 are defined herein, that are useful in the treatme... | 08/07/2007 |
| 7247626 | Pyrazolopyrimidine derivatives and pharmaceutical compositions containing them The present invention provides compounds of formula (I): pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents. ... | 07/24/2007 |
| 7244729 | 4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives The invention relates to 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula I wherein the symbols and substituents are as defined in the description, to processes for the preparation thereof, to pharmaceutical compositions comprising such derivatives and to the use ... | 07/17/2007 |
| 7244723 | Substituted furopyrimidinones as a mitotic kinesin inhibitors The present invention relates to furanopyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which ... | 07/17/2007 |
| 7229990 | Bicyclic heteroaromatic compounds A bicyclic heteroaromatic compound according to general formula I, or a pharmaceutically acceptable salt thereof, wherein R1 is (3–8C)cycloalkyl, (2–7C)heterocycloalkyl, (6–14C)aryl ... | 06/12/2007 |