Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 7018995 | Carbonate and carbamate modified forms of glucocorticoids Carbonates and carbamates of the formula and related steroid carbonates and carbamates are disclosed. The compounds are useful for treating rhinitis and asthma, particularly by inhalation, and for treating inflammation... | 03/28/2006 |
| 6861521 | Stereoselective transacetalization of steroidal C-22 acetonide The present invention is a process for the preparation of rofleponide of formula (II) where the 22R/22S ratio is 90/10 or greater which comprises contacting an acetonide of formula (I) | 03/01/2005 |
| 6197761 | 17ଲ-2-oxo-tetrahydrofuranyl)-carbothioic acid ester, -carboxylic acid ester and -carboxylic acid amide androstane derivatives Compounds of the androstane series are described having general formula ##STR1## and solvates thereof, in which R1 represents O, S or NH; R2 individually represents OC(.dbd.O)C1-6 alkyl; R3 individually represen... | 03/06/2001 |
| 5939409 | Processes for the production of anti-inflammatory steroids Disclosed are processes for preparing the 22R and 22S epimers of the compound ##STR1## The processes involve acetalization, transacetalization, hydrolysis (of an ester) or hydrogenation (of a diene) of an appropriate starting material. Also disc... | 08/17/1999 |
| 5888995 | Steroid esters The invention concerns compounds of formula I ##STR1## in which R1 is hydrogen or a straight or branched hydrocarbon chain; R2 is hydrogen or a straight or branched hydrocarbon chain; R3 is acyl; X1 is hydr... | 03/30/1999 |
| 5837698 | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs The present invention relates to a pharmaceutical composition or preparation which comprises hydroxyl containing steroidal hormones and organic nitrite/nitrate or other nitric oxide donating agents.... | 11/17/1998 |
| 5674861 | Fluorinated steroids Disclosed are the 22R and 22S epimers of compounds of the formula ##STR1## wherein X1 represents a fluorine atom, and X2 represents a hydrogen atom or a fluorine atom. Also disclosed are processes for the preparation of the comp... | 10/07/1997 |
| 5670676 | Process for preparation of 9 -chloro-11ଲ formyloxypregna-3.20-diones Disclosed is a process for producing a compound of the formula: ##STR1## by reacting a compound of the formula: ##STR2## with: (1) a chlorinating reagent selected from an N-chloroimide or an N-chloroamide; (2) an anhydrous strong acid selected f... | 09/23/1997 |
| 5616573 | Glucocorticoids Glucocorticoids of general formula I R--Val--O--GC (II), are described, in which O-GC is the radical of a 21-hydroxycorticoid that has an antiinflammatory action, Val represents a valine radical in the 21-position of the corticoid and R means a hydrogen atom or a h... | 04/01/1997 |
| 5602248 | Process for preparation of 9-chloro-11ଲ-formyloxypregna-3,20-diones Disclosed is a process for producing a compound of the formula: ##STR1## by reacting a compound of the formula: ##STR2## with: (1) a chlorinating reagent selected from an N-chloroimide or an N-chloroamide; (2) an anhydrous strong acid selected f... | 02/11/1997 |
| 5482934 | Pregna-1,4-diene3,20-dione-16-17-acetal-21 esters, process for their preparation, composition, and methods for the treatment of inflammatory conditions The present invention relates to compounds of the formula: ##STR1## in which X1 and X2 correspond to H or F without distinction; R1 represents the following radicals: ##STR2## and R2 represents the rad... | 01/09/1996 |
| 5215979 | 16,17-acetalsubstituted pregnane 21-oic acid derivatives The invention refers to compounds having activity against inflammatory, allergic, and dermatological conditions. The compounds are characterized by the formula ##STR1## or a stereoisomeric component thereof, in which formula R1 is sel... | 06/01/1993 |
| 5200518 | Anti-inflammatory carboxycyclic acetal pregnane derivatives Compounds of the formula: ##STR1## wherein X is H, F, Cl, or CH3 and Y is ##STR2## wherein R1 is H, alkyl of 1-5 carbon atoms, phenyl, or benzyl; R2 is COOR6, R5 COOR6, or R5 | 04/06/1993 |
| 5053404 | Novel steroid derivatives, pharmaceutical compositions containing them and process for preparing same The invention relates to antiinflammatory compounds of the formula (I), ##STR1## wherein A stands for hydrogen or hydroxyl group; X stands for hydrogen or halogen with the proviso that if A is hydrogen, then X also means hydrogen; R stands for hydrogen, b... | 10/01/1991 |
| 4820700 | Novel androstane-17ଲ-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions The invention refers to compounds having anti-inflammatory activity, characterized by the formula ##STR1## in the form of a stereoisomeric mixture or an epimer of the R or S type regarding the orientation of the substituents in the carbon atom at ... | 04/11/1989 |
| 4695625 | Process for the preparation of 16,17 acetals of pregnane derivatives A process for the preparation of 16,17 acetals of pregnane derivatives by trans-ketalization of 16,17-acetonides is described. In the instance of the preparation of 16,17-butylidenedioxy-11ଲ,21-dihydroxypregna-1,4-diene- 3,20-dione, a c... | 09/22/1987 |
| 4693999 | Liposomes containing steroid esters Pharmaceutical composition for administration primarily to the respiratory tract when treating and controlling anti-inflammatory conditions comprising liposomes in combination with a compound of the formula ##STR1## and R1 is a saturated o... | 09/15/1987 |
| 4613463 | Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid This invention discloses an improved process for the production of corticoids from 17-hydroxy steroids utilizing peroxymonosulfate.... | 09/23/1986 |
| 4456601 | 3-Chloro-pregnane derivatives and a process for the preparation thereof New Ɗ1,3,5 -3-chloro-pregnane derivatives of the general formula (I), ##STR1## wherein X is hydrogen atom, acetyl group or a chloroacetyl group, and Y and Z represent hydrogen atom or a halogen atom, with the proviso that at least one of ... | 06/26/1984 |
| 4432976 | Cyclocarbonate esters of 16,17, dihydroxy anti-inflammatory steroids Corticoids of Formula I ##STR1## wherein is a single bond or a double bond, X is hydrogen, fluorine, or chlorine, Y represents two hydrogen atoms or an oxygen atom, and Z is hydrogen or acyloxy of 2-6 carbon atoms, are pharmacologically active compounds... | 02/21/1984 |
| 4404141 | Ɗ9(11) - And Ɗ16 -21-chloro-20-keto steroids of the pregnane and D-homopregnane series, their preparation and use as intermediates for the synthesis of highly effective corticoids Ɗ16 - and Ɗ17 -21-chloro-20-keto steroids of the formula ##STR1## wherein n is 1 or 2, C1 C2 and C9 C11 represent a CC-single or CC-double bond, R1 is H or OH, R2 | 09/13/1983 |
| 4390533 | Steroids and process for preparing the same The present invention relates to 2-chloro-6ଲ-fluoro-pregna-1,4-diene-3,20-diones having good anti-inflammatory activity, to processes for their preparation and pharmaceutical compositions thereof.... | 06/28/1983 |
| 4383992 | Water-soluble steroid compounds Beta-cyclodextrin forms a water-soluble complex or inclusion compound with steroid compounds having a molecular structure smaller than the interior cavity in the doughnut-shaped molecular structure of beta-cyclodextrin. The resulting inclusion compounds c... | 05/17/1983 |
| 4376767 | Pyridylmethyl esters of selected bio-affecting carboxylic acids Novel pharmaceutically useful derivatives of selected known bio-affecting carboxylic acids are disclosed, said derivatives having the structural formula ##STR1## wherein R1 and R2, which can be the same or different, are each ... | 03/15/1983 |
| 4340538 | Process for producing 6-fluoro-Ɗ1,4 -3-keto steroids Two processes are disclosed (one-pot and two-pot) for the transformation of a 6ଲ-fluoro-Ɗ1,4 -3-keto steroid (IV) to a 6-fluoro-Ɗ1,4 -3-keto steroid (VI). These processes permit the introduction of a fluorine atom at t... | 07/20/1982 |
| 4275061 | Steroids and process for preparing the same The present invention relates to 2-chloro-6ଲ-fluoropregna-1,4-diene-3,20-diones having good anti-inflammatory activity, to processes for their preparation and pharmaceutical compositions thereof.... | 06/23/1981 |
| 4273710 | Process for preparing flunisolide A unique crystalline form of flunisolide is prepared by crystallizing flunisolide from a solution of an alkanol of three or four carbon atoms, e.g. n-butanol, containing 0.2 to 5%, preferably 1.0 to 4.0% by volume water.... | 06/16/1981 |
| 4273770 | 4-Halo steroids Certain pregn-4-ene-3,20-diones or pregn-1,4-diene-3,20-diones 4-substituted with a fluoro or chloro are useful as topical anti-inflammatory steroids. These compounds are substituted at 9 with hydrogen, fluoro, chloro or bromo; at 6 with hyd... | 06/16/1981 |
| 4272446 | Steroids and process for preparing the same Novel steroids are described together with processes of making them and pharmaceutical compositions containing them. The steroids have pharmaceutical activity, especially antiinflammatory activity. They are all 2-Bromo-6ଲ-fluoro-pregna-1,4-diene-3,2... | 06/09/1981 |
| 4267173 | Use of 6ଲ-fluoro-7-halogenocorticoids as topical anti-inflammatories and pharmaceutical formulations useful therefor Described is the use of 6ଲ-fluoro-7-halogeno-1,4-pregnadiene-17,21-diol-3,20-di ones and their esters as topical anti-inflammatory agents, and pharmaceutical formulations thereof useful therefor. Preferred compounds are 6ଲ,9&... | 05/12/1981 |
| 4230621 | Steroid derivatives and their use in radioimmunoassays Radiolabeled steroid derivatives having the formula ##STR1## wherein St is a des-hydroxy steroid moiety of (i) a hydroxy steroid intended for radioimmunoassay or (ii) a hydroxy containing derivative of a steroid intended for radioimmunoassay, said de... | 10/28/1980 |
| 4226862 | Steroids and process for preparing the same Novel steroids are described together with processes of making them and pharmaceutical compositions containing them. The steroids have pharmaceutical activity, especially anti-inflammatory activity. They are all 2-Bromo-6ଲ-fluoro-pregna-1,4-diene-3,... | 10/07/1980 |
| 4221787 | Esteramide prodrugs of anti-inflammatory corticosteroids Transient, C-21 and/or C-17 esteramide prodrugs of the anti-inflammatory corticosteroids, prepared by esterification of hydroxy steroids, are disclosed.... | 09/09/1980 |
| 4221786 | Novel halogenopregnadienes and process for the manufacture thereof The invention relates to the preparation of polyhalogenated pregnane derivatives of the formula ##STR1## wherein X represents fluorine or chlorine and R a free or esterified hydroxyl group or chlorine. The new compounds display a high antiinflam... | 09/09/1980 |
| 4201778 | 6-Acyloxy-1,4,6-pregnatrienes, their use as anti-inflammatory agents, methods for their manufacture, and 6-oxo-1,4-pregnadiene intermediates Novel 6-acyloxy-3,20-dioxo-1,4,6-pregnatrienes and 6-acyloxy-3,20-dioxo-4,6-pregnadienes, useful anti-inflammatory agents, are prepared by reaction of the corresponding 3,6,20-trioxo-1,4-pregnadiene or 3,6,20-trioxo-4-pregnene with an acyl halide or ... | 05/06/1980 |
| 4198403 | 17 Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes Certain 3-oxoandrost-4-ene and 3-oxoandrosta-1,4-diene 17 beta-thiocarboxylic acid esters substituted at the 4-position with a fluoro, chloro or bromo and optionally substituted at the six position with fluoro or chloro are useful as anti-inflammatory ste... | 04/15/1980 |
| 4198336 | Chemical process for preparing androsta-4-ene 17-carboxylic acids This invention is a process for preparing 3-keto-androst-4-ene 17-carboxylic acids, androsta-1,4-diene 17-carboxylic acids and their 17-esters by reacting a corresponding 21-hydroxypregn-4-ene-3,20-dione, 21-hydroxypregna-1,4-diene-3,... | 04/15/1980 |
| 4181720 | Corticosteroid antiinflammatory agents 22-Optionally substituted steroids of the corticoid series are prepared from the corresponding 21-methylene steroids through the 20,21-dione steroid intermediates. These compounds have utility as anti-inflammatory agents.... | 01/01/1980 |
| 4150126 | Novel enol esters of steroids, compositions containing such compounds, processes for their preparation and methods of treatment therewith This invention relates to novel enol esters of steroids having an antitumor activity and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds and methods of treatment therewith.... | 04/17/1979 |
| 4124707 | 7-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor Novel 3,20-dioxo-7-halogeno-1,4-pregnadienes are described and their use as anti-inflammatory agents. Preferred are 7-bromo- and 7-chloro- derivatives, particularly 7-bromo- and 7-chloro-1,4-pregnadienes-11ଲ,17�... | 11/07/1978 |
