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A method of swing on a swing is disclosed, in which a user positioned on a standard swing suspended by two chains from a substantially horizontal tree branch induces side to side motion by pulling alternately on one chain and then the other.
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| Number | Title | Issue Date |
| 7662956 | Tetrahydrobenzo[d]azepin-2-one derivatives and the use thereof for treating cardiovascular diseases The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases... | 02/16/2010 |
| 7589195 | Tetrahydrobenzo[d]azepin-2-one derivatives and the use thereof for treating cardiovascular diseases The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases... | 09/15/2009 |
| 7225079 | System and method for automated matched ion polynucleotide chromatography In an extensive Matched Ion Polynucleotide Chromatography (MIPC) system and method, and the computer programs or software associated therewith, the system provides automated options for sample selection, mobile phase gradient selection and control, column and mobile... | 05/29/2007 |
| 7008938 | Benzene-fused heteroring derivatives and pharmaceutical agents comprising the same as active ingredient A benzene-fused heteroring derivative of formula (I) wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cyst... | 03/07/2006 |
| 6919332 | N-substituted-heteroaryloxy-aryloxy-pyrimidine-2,4,6-trione metalloproteinase inhibitors The present invention relates to N-substituted-heteroaryloxy-aryloxy-2,4,6-trione metalloproteinase inhibitors of the formula wherein X, A, Y, B, G, and R1 are as defined in the specification, and to pharmac... | 07/19/2005 |
| 6602864 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds The compounds of formula I herein exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More specifically, they are inhibit... | 08/05/2003 |
| 6534496 | Thermogenic composition and benzazepine thermogenics The object of the present invention is to provide a prophylactic and/or therapeutic drug for obesity and obesity-associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the present inv... | 03/18/2003 |
| 6489354 | 3-alkyl substituted pyrrolidine modulators of chemokine receptor activity The present invention is directed to pyrrolidine compounds of the formula I: ##STR1## (wherein R1, R2, R3, R4c, R4d, and R4f are defined herein) which are useful as modulators of chemokine ... | 12/03/2002 |
| 6372764 | Pyrrolidine modulators of chemokine receptor activity The present invention is directed to pyrrolidine compounds of the formula I: ##STR1## (wherein R1, R2, R3, R4c, R4d, and R4f are defined herein) which are useful as modulators of chemokine ... | 04/16/2002 |
| 6346527 | Guanidine derivatives A compound of the formula: ##STR1## wherein R1 is hydrogen or halogen, R2 is hydroxy, acyl(lower)alkoxy, hydroxy(lower)alkyl, lower alkoxy(lower)alkyl, lower alkylthio(lower)alkyl, mono(or di or tri)halo(lower)alkyl, (ethoxycarbonyl)... | 02/12/2002 |
| 6281227 | Sulfonic acid sulfonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds The compounds of formula I herein exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More specifically, they are inhibit... | 08/28/2001 |
| 6166037 | Pyrrolidine and piperidine modulators of chemokine receptor activity The present invention is directed to pyrrolidine and piperidine compounds of the formula I: ##STR1## (wherein R1, R2, R3, R4a, R4b, R4c, R4d, R4e, R4f,... | 12/26/2000 |
| 5914319 | Antithrombotic agents This invention relates to thrombin inhibiting compounds having the Formula I X--Y--NH--(CH2)r --G I where X, Y, r and G have the values defined in the description, as well as pharmaceutical formulations contain... | 06/22/1999 |
| 5910494 | Hypolipidemic 1,4-benzothiazepine-1,1-dioxides The invention is concerned with novel hypolipidemic compounds of formula (I), with processes and novel intermedites for their preparation, pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and trea... | 06/08/1999 |
| 5726159 | Antithrombotic agents This invention relates to thrombin inhibiting compounds having the Formula I X--Y--NH--(CH2)r --G I where X, Y, r and G have the values defined in the description, as well as pharmaceutical formulations containi... | 03/10/1998 |
| 5710130 | Antithrombotic agents This invention relates to thrombin inhibiting compounds having the Formula I X--Y--NH--(CH2)r --G I where X, Y, r and G have the values defined in the description, as well as pharmaceutical formulations containi... | 01/20/1998 |
| 5707967 | Pain relief compositions Disclosed are compositions containing either aspartame or monosodium glutanate combined with an amino acid.... | 01/13/1998 |
| 5707966 | Antithrombotic agents This invention relates to thrombin inhibiting compounds having the Formula I X--Y--NH--(CH2)r --G I where X, Y, r and G have the values defined in the description, as well as pharmaceutical formulations containi... | 01/13/1998 |
| 5705487 | Antithrombotic agents This invention relates to thrombin inhibiting compounds having the Formula I X--Y--NH--(CH2)r --G I where X, Y, r and G have the values defined in the description, as well as pharmaceutical formulations containi... | 01/06/1998 |
| 5658899 | Acid addition salts of 2, 3, 4, 5-tetrahydro-1H-3-benzazepine compounds The invention provides a series of crystalline salts of (S)-8-chloro-5-(5-bromo-2,3-dihydrobenzofuran-7-yl)-3-methyl-2,3,4,5-tetra hydro-1H-3-benzazepine-7-ol, their preparation and use as therapeutic agents.... | 08/19/1997 |
| 5599793 | Antithromobotic agents This invention relates to L-arginine aldehyde derivatives, having the Formula I ##STR1## where X and Y have the values defined in the description, as well as pharmaceutical formulations containing those compounds and methods of their use as thro... | 02/04/1997 |
| 5530125 | Synthesis of -substituted-aryl ethylamines A novel process for the preparation of -substituted arylacetamides wherein the substituent is an aromatic group or a 1-alkenyl or 1-cycloalkenyl group and wherein the nitrogen atom carries no hydrogen atoms comprises the reaction of an arylacetamid... | 06/25/1996 |
| 5470850 | 2,3,4,5-tetrahydro-1H-3-benzazepines 2,3,4,5-Tetrahydro-1H-3-benzazepines having the general formula ##STR1## wherein R1 is Cl or Br; R3 and R4 are hydrogen, halogen, CF3, CN, NO2, or NH2. The compounds are useful in treatment... | 11/28/1995 |
| 5461148 | Process for preparing benzazepine intermediates for the synthesis of D1 antagonists Disclosed are a process and intermediates of the formulae ##STR1## wherein R is --CH2 OH or --OH and R3 is H or C1 -C6 alkyl; useful for preparing benzazepines of the formula ##STR2## having activity a... | 10/24/1995 |
| 5446147 | Fluorinated and iodinated dopamine agents This invention relates to novel dopamine D-1 and D-2 imaginging agents which are both fluorinated and iodinated and can appropriately labelled for use in both PET and SPECT imaging. Compounds include S-(-)-2-fluoroethoxy-3-methyl-N-[(1-ethyl-2-pyrrolidiny... | 08/29/1995 |
| 5273974 | Condensed heterocyclic compounds, their production and use A condensed heterocyclic derivative of the formula (I): ##STR1## wherein X is an oxygen atom, a sulfur atom or R1 --N< wherein R1 is a hydrogen atom, a hydrocarbon group which may be substituted or an acyl group which may be sub... | 12/28/1993 |
| 5244881 | Compositions based on imipyramine The invention provides new inclusion compounds based on imipramine and cyclodextrin and pharmaceutical compositions which can be administered orally and are based on these new inclusion compounds.... | 09/14/1993 |
| 5079243 | Benzazepines Novel 2, 3, 4, 5-tetrahydro-1H-3-benzazepines, which in the 7-position have a methoxymethyloxy group, in the 8-position hydrogen, halogen, or a nitro group and in the 5-position have an optionally substituted phenyl ortho-fused ring-system, with interesti... | 01/07/1992 |
| 5017571 | Carbamic acid ester of substituted 7-hydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines Compounds having the formula ##STR1## wherein R1, R4, R6, R7, and R8 are hydrogen or a substituent, R2 is a substituent, R5 is an optionally-substituted bicyclic ring system... | 05/21/1991 |
| 5015639 | Substituted benzazepines, their preparation and pharmaceutical compositions containing them Disclosed herein are novel 1-substituted-2,3,4,5-tetrahydro-1H-3-benzazepines of the general formula I: ##STR1## wherein R1, R2, R3, R4 and R5 are specified substituents. R1 is pr... | 05/14/1991 |
| 5010074 | Novel benzazepine derivatives Novel 2,3,4,5-tetrahydro-1H-3-benzazepines having the formula ##STR1## wherein R3 represents H, C1-3 -alkyl or C3-7 -cycloalkyl; R4 represents hydrogen or R4 together with R10 represents a ... | 04/23/1991 |
| 4861771 | Carbamates of 6-chloro-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benz azepine as prodrugs Prodrug carbamate derivatives of fenoldopam which provide fenoldopam plasma levels of similar magnitude and over a much longer period of time than the parent compound. An absence of a high initial peak effect associated with the parent compound is noted. ... | 08/29/1989 |
| 4824839 | Sulfinyl and sulfonyl substituted 2,3,4,5 tetrahydro-1H-3-benzazepines and their use in treating gastrointestinal motility disorders Sulfinyl and sulfonyl substituted 3-benzazepine compounds are useful in treating gastrointestinal motility disorders and emesis. A particular compound of this invention is 7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine.... | 04/25/1989 |
| 4751222 | 2,3,4,5-tetrahydro-1H-3-benzazepines and CNS affecting use thereof Novel 2,3,4,5-tetrahydro-1H-3-benzazepines which in the 5-position have furyl, thienyl, pyridyl, or ring systems consisting of phenyl ortho condensed with a benzen, cyclohexan, cyclohexen, cyclopentan or cyclopenten ring wherein one of the carbon atoms ma... | 06/14/1988 |
| 4749559 | Method for detecting melanin-containing matter The present invention discloses a method of detecting melanin containing matter comprising reacting melanin containing matter with an enantiomer of 2, 3, 4, 5-tetrahydro-3-methyl-5 phenyl-1H-3-benzazepin-7-ol and determining the binding of said enantiomer... | 06/07/1988 |
| 4707483 | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders 1-Phenyl-3-benzazepine compounds are useful in treating gastrointestinal motility disorders. A particular compound of this invention is 8-hydroxy-3-methyl-1-phenyl-7-phenylthio-2,3,4,5-tetrahydro-1H-3-benzazepi ne.... | 11/17/1987 |
| 4705862 | Chemical processes for 2-(2-halo-3,4-dimethoxybenzyl)-5-(4-methoxyphenyl)oxazolidines New intermediates, namely 2-(2-halo-3,4-dimethoxybenzyl)-5-(4-methoxyphenyl)-oxazolidines, are prepared by a synthetic sequence which uses a Darzen's reaction in a homogeneous solvent system.... | 11/10/1987 |
| 4600714 | Fenoldopam 4',8-bis-hydrogen sulfate and dopaminergic use thereof Fenoldopam 4',8-bis-hydrogen sulfate and its salts are useful prodrugs to obtain extended dopaminergic activity. A useful species is the monoammonium salt.... | 07/15/1986 |
| 4514394 | Anti-hypertensive use of 1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benz azepines 6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines whose structures have an isopropylsulfonyl, isopropylthio, isobutylsulfonyl or isobutylthio group substituted at the 4-position of the 1-phenyl substituent have potent renal dopaminergic... | 04/30/1985 |
| 4477378 | Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines Disclosed are esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1-H-3-benzazepines represented by the general formula I ##STR1## wherein X is chloro, bromo or trifluoromethyl; R1 is alkyl, aralkyl, aryl, alkoxyalkyl, aryloxy... | 10/16/1984 |
