Class 540/571 - Nitrogen bonded directly to ring carbon of the hetero ring

Subclass of Class 540 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein nitrogen is bonded directly to ring carbon
No. of patents: 21
Last issue date: 04/15/2008

Number	Title	Issue Date
7358239	Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives The present invention concerns compounds of formula (I) a stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereof, wherein -Z1-Z2- is...	04/15/2008
6642223	Benzoheterocyclic derivatives A benzoheterocyclic derivative of the following formula [1]: ##STR1## and pharmaceutically acceptable salts thereof, which show excellent anti-vasopressin activity, vasopressin agonistic activity and oxytocin antagonistic activity, and are useful as a vas...	11/04/2003
6140322	Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase There are provided novel compounds of formula (I) ##STR1## wherein X, R1, R2, R3, R4 and R5 are as defined in the specification and optical isomers and racemates thereof and pharmaceutically acce...	10/31/2000
6096735	Benzoheterocyclic derivatives A benzoheterocyclic derivative of the following formula [1]: ##STR1## and pharmaceutically acceptable salts thereof, which show excellent anti-vasopressin activity, vasopressin agonistic activity and oxytocin antagonistic activity, and are useful as ...	08/01/2000
5580979	Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions The present invention makes available novel compounds represented by the general formula ##STR1## wherein Y represents a phosphate analog. Which compounds are useful for inhibiting an interaction between a protein containing an SH2 domain and a ...	12/03/1996
5175159	3-substituted-1,4-benzodiazepines as oxytocin antagonists Compounds of Formula I are antagonists of oxytocin and are useful in the treatment of preterm labor and dysmenorrhea, and for stoppage of labor prepatory to Caesarean delivery. ##STR1##...	12/29/1992
5141735	Substituted amino-benzodiazepines having anitviral activity Novel substituted 2-amino-5-(1H-pyrrol-2-yl)-3H-1,4-benzodiazepines and compositions containing same for treatment and prophylaxis of viral infections, including HIV infections....	08/25/1992
4978753	7-phenylpyrimido[1,2-alpha][1,4]benzodiazepin-3(5H)-ones A 7-phenylpyrimido[1,2-a][1,4]benzodiazepin-3(5H)-ones of the formula II: ##STR1## wherein Ro is selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms, inclusive, --COOR in which R is alkyl defined as above, ##S...	12/18/1990
4820834	Benzodiazepine analogs Benzodiazepine analogs of the formula: ##STR1## are disclosed which are antagonists of gastrin and cholecystokinin (CCK)....	04/11/1989
4755508	Benzodiazepine analogs and use as antogonists of gastrin and cholecystokinin Benzodiazepines of the formula: ##STR1## are disclosed which are antagonists of gastrin and cholecystokinin (CCK)....	07/05/1988
4739049	Phosphorylation of cyclic amides Compounds of the general formula ##STR1## are reacted with a strong base followed by a phosphorylating agent, such as dicyclicaminophosphinic halide or bis-di-lower alkylaminophosphinic halide to produce an imine of the formula ##STR2## whe...	04/19/1988
4280957	Imidazodiazepines and processes therefor Novel Imidazobenzodiazepines and their analogs are useful as anticonvulsants, muscle relaxant, anxiolytic and sedative agents. Preferred compounds of this class belong to the imidazo[1,5-a][1,4]diazepine series which may have a very wide variety of o...	07/28/1981
4083948	Benzodiazepine radioimmunoassay using I125-label An improved radioimmunoassay for benzodiazepines such as diazepam, chlordiazepoxide, oxazepam, demoxepam and metabolites thereof is disclosed. Such immunoassay employs novel 125 I-labelled 4'-hydroxy derivatives of these compounds as tracer....	04/11/1978
4082761	Triazolo[4,3-a][1,4]benzodiazepinium quaternary salts This invention relates to novel benzodiazepinium compounds of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, lower alkyl of 1 through 3 carbon atoms, hydroxy, mercapto, amino, monoalkylamino of 1 through 3 carbon at...	04/04/1978
4082764	Methods for the production of 4H-s-triazolo[4,3-a][1,4]benzodiazepine 5N-oxides The title compounds are prepared by reacting a 3-amino-3,4-dihydro-4-hydroxy-4-phenylquinazoline with a reactive derivative of a halogenoacetic acid, reacting the resultant halogenoacetyl derivative with a weak acid, reacting the resultant 2-(3-halom...	04/04/1978
4065474	1,4-Benzodiazepine-2-amine derivatives Benzodiazepine derivatives having the general formula I: ##STR1## wherein R1 represents a hydrogen or halogen atom or a trifluoromethyl, cyano, nitro, lower alkyl, lower alkoxy or lower alkyl thio group; R2 represents a lower al...	12/27/1977
4008223	6-Aza-3H-1,4-benzodiazepines There are produced 6-aza-3H-1, 4-benzodiazepines and 6-aza-1,2-dihydro-3H-1,4-benzodiazepines of the formula ##STR1## where R1 is a halogen, R2 and R3 are hydrogen, halogen, trifluoromethyl, nitro, nitrile, hydroxy, l...	02/15/1977
4005099	1-[(Dimethylamino)-methyl]-6-aryl-4H-imidazo[1,5-a][1,4]benzodiazepines Compounds of the formula III ##STR1## wherein R1 is hydrogen or methyl; wherein R2 is hydrogen, fluoro, chloro, bromo, trifluoromethyl, or nitro; and wherein Ar is phenyl, o-chlorophenyl, o-fluorophenyl, o,o-difluorophenyl, or 2...	01/25/1977
3972873	Certain pyrido[3,2-e]1,4-diazepinones and derivatives There are prepared compounds of the formula: ##SPC1## Wherein: n is an integer from 1 to 4; R1 is alkyl of 1 to 6 carbon atoms, a hydroxy group, an amino group, an alkoxy group having 1 to 6 carbon atoms, a phenyl group or a phenyl group substi...	08/03/1976
3941775	6-Aza-3H-1,4-benzodiazepines There are produced 6-aza-3H-1,4-benzodiazepines and 6-aza-1,2-dihydro-3H-1,4-benzodiazepines of the formula: ##SPC1## Wherein R1 is the group --NRa Rb, --NRa Rb Rc or --NRa acyl ...	03/02/1976
3933794	2-(2-Alkynylamino)-3H-1,4-benzodiazepines Novel 6-substituted 4H-imidazo[1,2-a][1,4]benzodiazepines, the intermediate 5-substituted-2-(2-alkynylamino)-3H-1,4-benzodiazepines, pharmacologically acceptable acid addition salts thereof, and processes for their production. The compounds of this invent...	01/20/1976

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Class 540/571 - Nitrogen bonded directly to ring carbon of the hetero ring