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Class 540/57 - The hetero ring is ortho-fused to the A ring


Subclass of Class 540 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which the hetero ring is ortho-fused to the
No. of patents: 14
Last issue date: 03/11/2008


NumberTitleIssue Date
7342004Thioether sulphamate steroids as steroid inhibitors and anti-cancer compounds
There is provided use of a compound of Formula XI: wherein R3 is a sulphamate group and at least of R1 or R2 is a thioether group as disclosed by the present specification, capable of inhibi...
03/11/2008
71125803-nitrogen-6, 7-dioxygen steroids and uses related thereto
A compound of the formula: and pharmaceutically acceptable salts, solvates, stereoisomers and prodrugs thereof, in isolation or in mixture, wherein R groups are as defined by the present specification. The compou...
09/26/2006
7041839Steroidal antiestrogens and antiandrogens and uses thereof
The present invention comprises the design, synthesis and development of a new class of chemotherapeutic agents for prophylactic and therapeutic treatments in a mammal, particularly a human, believed to be at risk of suffering from a hormone-responsive disorde. In a...
05/09/2006
5134135Antiandrogenic sulfonylsteroidooxazoles
2'-Alkylsulfonylsteroido[2,3-d]oxazoles, for example 2'-methylsulfonyl-5଱-pregn-2-en-20-yno[2,3-d]oxazol-17ଲ-ol, which are useful as antiandrogenic agents, and proceses for preparation, method of use and compositions thereof are disclosed....
07/28/1992
5053405Antiandrogenic sulfonylsteroidothiazoles
2'-Alkylsulfonylsteroido[3,2-d]thiazoles, for example 2'-methylsulfonyl-5଱-pregn-2-en-20-yno[3,2-d]thiazol-17ଲ-ol, which are useful as antiandrogenic agents, and processes for preparation, method of use and compositions thereof are disclosed....
10/01/1991
4755595Enhanced production of 4,5-unsaturated steroids utilizing methanol solvation
An improvement in the epoxidation of certain 4,5-unsaturated steroids with peracetic acid, which comprises carrying out the reaction in methanol solution....
07/05/1988
4634696Novel 11 beta-substituted-19-nor-steroids
Novel 19-nor-steroids of the formula ##STR1## wherein R1 is an organic group of 1 to 18 carbon atoms optionally containing at least one heteroatom with the atom immediately adjacent the 11-carbon atom being carbon, R2 is a hydro...
01/06/1987
4605517Method of preparing steroid compounds of controlled particle size
The method of preparing a 2଱-cyano-4଱,5଱-epoxy-3-oxo steroid or a steroid fused at the 2- and 3-positions with a heterocyclic ring of controlled particle size which comprises dissolving the steroid in an organic solvent, precipitating th...
08/12/1986
43494742-Cyanosteroids
The invention relates to novel 2-cyanosteroids of Formula I which are useful for the induction of menses and the termination of pregnancy....
09/14/1982
43316634଱,5଱-Epoxy-3,20-dioxopregnan e-2଱,16଱-dicarbonitrile and intermediates and process for preparation, method of use and compositions thereof
4଱,5଱-Epoxy-3,20-dioxopregnane-2଱,16଱-dicarbonitril e is prepared by decyclizing 4଱,5଱-epoxy-20-oxopregn-2-eno-[2,3-d]isoxazole-16଱-carbo nitrile with strong base and is useful as an inhibitor of mineralocorticoid ...
05/25/1982
4297350Male contraceptive steroids and methods of use
The steroids of the present invention have been found to be useful as male contraceptives when administered orally. Upon cessation of administration of the male contraceptive steroids of the present invention the male promptly regains normal fertility....
10/27/1981
4160027Steroid cyanoketones and intermediates
2଱-Cyano-3-oxosteroids having a 4଱,5଱-epoxy group and alkylated in the 4- and/or 6-position, useful as interceptive agents, are prepared by alkaline cleavage of the corresponding steroido[2,3-d]isoxazoles....
07/03/1979
4055562Process for preparing pregn-20-yne compounds and novel product produced thereby
A process for preparing 17ଲ-hydroxysteroido[2,3-d]isoxazoles substituted at the 17଱-position by an ethynyl or substituted ethynyl group comprising reacting a 17-oxosteroido[2,3-d]isoxazole with the appropriate ethynylmagnesium halide, substitu...
10/25/1977
3980638Testosterone derivatives
Novel testosterone 17-ether 2,3-isoxazole and 2-cyano derivatives are disclosed as useful steroid enzyme inhibitors and for other pharmaceutical purposes....
09/14/1976
 
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