A method of swing on a swing is disclosed, in which a user positioned on a standard swing suspended by two chains from a substantially horizontal tree branch induces side to side motion by pulling alternately on one chain and then the other.
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| Number | Title | Issue Date |
| 8093380 | Compounds with the bicyclo[4.2.1]nonane system for the treatment of infections The disclosed invention is a bicyclo[4.2.1]nonane and its pharmaceutically acceptable salt or prodrug, and its composition and method of use to treat Flaviviridae (Hepacivirus, Flavivirus, and Pestivirus) infections in a host, including animals, and especially human... | 01/10/2012 |
| 7335677 | Inhibitors of dipeptidyl peptidase IV Novel compounds that are inhibitors of one or most post-proline cleaving proteases, e.g. dipeptidyl peptidase IV, according to general formula (1). R1 is H or CN, X1 is O, S, CH2, CHF, CF2, CH(CH3), C(CH3 | 02/26/2008 |
| 7332490 | Methods and compositions of novel triazine compounds The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced... | 02/19/2008 |
| 7307079 | 1,3,5-Triazine derivatives as ligands for human adenosine-A3 receptors The invention relates to a group of novel triazine derivatives which are ligands for human adenosine-A3 receptors, as well as to pharmaceutical compositions containing a pharmacologically active amount of at least one of these compounds as an active ingre... | 12/11/2007 |
| 7273857 | Benzimidazolidinone derivatives as muscarinic agents Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the s... | 09/25/2007 |
| 7271154 | Antibiotic conjugates This invention features a compound of the following formula: wherein T is a transportophore, L is a bond or linker, and C is an antibiotic therapeutic agent, the transportophore is covalently bonded to the antibi... | 09/18/2007 |
| 7268134 | Medical devices employing triazine compounds and compositions thereof The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced... | 09/11/2007 |
| 7265114 | Methods and compositions of novel triazine compounds The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced... | 09/04/2007 |
| 7186709 | Dihydropyrancarboxamides and uses thereof The present invention provides novel dihydropyrancarboxamide compounds of formula (I): and collections of these compounds, and provides methods for the synthesis of these compounds; wherein R1–R... | 03/06/2007 |
| 7173054 | Respiratory syncytial virus replication inhibitors This invention concerns the use of compounds of formula (I) wherein -a1=a2-a3=a4- is a radical of formula —CH═CH—CH═CH—, —N═CH—CH═CH—, —CH═N—CH═CH—, —CH═CH—N═CH—, —CH═CH—CH═N... | 02/06/2007 |
| 7148242 | N-formyl hydroxylamine compounds, compositions and methods of use N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylamino-aryl or -heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes or imidazacyclo4-7alkanes have interesting properties, e.g., in the treatment or prevention of disorders ... | 12/12/2006 |
| 7125877 | Benzimidazole derivatives This invention provides compounds which are represented by a general formula [I] [in which X stands for hydrogen or halogen; B stands for halogen, cyano or optionally fluorine-substituted lower alkyl; D stands fo... | 10/24/2006 |
| 7122534 | Aryl fused azapolycyclic compounds The present invention relates to compounds of formula (I) and their pharmaceutically acceptable salts, wherein R1, R2, R3 and Z are as defined herein, intermediates in the synthesis of ... | 10/17/2006 |
| 7112587 | Methods and compositions of novel triazine compounds The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced... | 09/26/2006 |
| 7091199 | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d antagonists The compounds are of the class of thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives, useful as D4 antagonists. Said compounds are useful for the treatment of medical conditions mediated by inhibition of D4 receptor. These condi... | 08/15/2006 |
| 7087593 | Benzimidazolidinone derivatives as muscarinic agents Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the s... | 08/08/2006 |
| 7018996 | Antibiotics AW998A, AW998B, AW998C and AW998D This invention relates to antibiotics selected from the group AW998A, AW998B, AW998C and AW998D derived from the microorganism Streptomyces designated LL-AW998, which are useful as antibacterial agents. ... | 03/28/2006 |
| 7008957 | Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments The invention relates to compounds of the formula I in which the radicals have the stated meanings, their stereoisomeric forms and their physiologically tolerated salts and process for their preparation. The com... | 03/07/2006 |
| 6967188 | Selective heteroaryloxy- acetamides-based herbicides The invention relates to novel herbicidal synergistic active compound combinations comprising heteroaryloxy-acetamides and known herbicidally active compounds and/or safeners described in the description and their use for the selective control of weeds in crops of v... | 11/22/2005 |
| 6921822 | Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives The present invention relates to a process for preparing stereoisomerically enriched 4-aryl-4-hydroxybutanoic acid derivatives by reducing 4-aryl-4-ketobutanoic acid derivatives in the presence of ruthenium-containing catalysts. ... | 07/26/2005 |
| 6919329 | N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives The present invention provides antibacterial agents having the formulae I, II, and III described herein. ... | 07/19/2005 |
| 6749988 | Amine compounds, resist compositions and patterning process Novel amine compounds having a nitrogen-containing cyclic structure and a hydrating group such as a hydroxy, ether, ester, carbonyl, carbonate group or lactone ring are useful for use in resist compositions for preventing a resist film from thinning and also for enh... | 06/15/2004 |
| 6706702 | Aryl fused azapolycyclic compounds The present invention relates to compounds of formula (I) and their pharmaceutically acceptable salts, wherein R1, R2, R3 and Z are as defined herein, intermediates in the synthesis of su... | 03/16/2004 |
| 6630475 | Adenosine A2a receptor antagonists Compounds having the structural formula I ##STR1## or a pharmaceutically acceptable salt thereof, wherein R is optionally substituted phenyl, cycloalkenyl, or heteroaryl; X is alkylene or --C(O)CH2 --; Y is --N(R2)CH2 CH... | 10/07/2003 |
| 6627624 | Aryl fused aminoalkyl-imidazole derivatives: selective modulators of GABAa receptors Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable non-toxic salts thereof wherein the A, B, C, D, X, R1, R2, R3, R4, R5, and R6, are variables defined here... | 09/30/2003 |
| 6620823 | Lactam metalloprotease inhibitors The present application describes novel lactams and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein ring B is a 4-8 membered cyclic amide comprising 0-3 additional heteroatoms selected from N, O, ... | 09/16/2003 |
| 6608070 | 2,3-substituted indole compounds as anti-inflammatory and analgesic agents This invention provides a compound of the following formula: ##STR1## or the pharmaceutically acceptable salts thereof wherein Z is OH, C1-6 alkoxy, --NR2R3 or heterocycle; Q is selected from the following: (a) an optionally substituted phenyl, (b) an opt... | 08/19/2003 |
| 6545000 | [1,2,4]triazolo[1,5-c]pyrimidine derivatives The present invention relates to [1,2,4]triazolo[1,5-c]pyrimidine compounds represented by formula (I): ##STR1## wherein na and nb independently represent an integer of 0 to 4 and Q represents a hydrogen atom or 3,4-dimethoxybenzyl, or salts thereof ... | 04/08/2003 |
| 6448242 | Cyclic amide compounds The invention relates to compounds represented by the following general formula (1): ##STR1## wherein A is an aromatic compound which may be substituted, or the like, B is a nitrogen atom or CH, X is a lower alkylene group which may be substituted, o... | 09/10/2002 |
| 6429205 | Nitrogen containing heterobicycles as factor Xa inhibitors This invention relates generally to nitrogen containing heterobicycles of formulas A and B: ##STR1## which are inhibitors of trypsin-like serine protease enzymes, especially factor Xa, pharmaceutical compositions containing the same, and methods of u... | 08/06/2002 |
| 6420395 | Azacyclooctane and heptane derivatives, their preparation and use in therapy The present invention discloses compounds of formula (1) or (2), any of its enantiomers or any mixture thereof, or a pharmaceutically acceptable salt thereof; wherein n is 0, or 1; R is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalky-alkyl, aryl ... | 07/16/2002 |
| 6387512 | Grey coloring photochromic fused pyrans A photochromic grey coloring 2H-naphtho[1,2-b]pyran of formula (1) wherein R1 is selected from mono-, di- or poly-substituted aryl groups, mono-, di- or poly-substituted naphthyl groups and mono-, di- or poly-substituted heteroaryl groups, wher... | 05/14/2002 |
| 6362177 | Cyclic amine derivatives and their use as drugs ##STR1## A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1 -C6 alkyl addition salt thereof, and their medical applications. These compounds... | 03/26/2002 |
| 6358942 | Phenyloxazolidinones having a c-c bond 4-8 membered heterocyclic rings A compound of Formula (I): ##STR1## or pharmaceutical acceptable salts thereof wherein X is NR1 ; R1 is H, C1-6 alkyl optionally substituted with one or more OH, CN, or halo, or R1 is --(CH2)h | 03/19/2002 |
| 6352981 | Substituted AZA- and diazacycloheptane and -cyclooctane Aza- and diazacyclohexane and -cyclooctane compounds of the following formula: Ar1 --A--B--Ar2 (I) where Ar1, A, B and Ar2 have the meanings stated in the description have a high affinity for the dopamine D3 | 03/05/2002 |
| 6207825 | Method for production of pyrrolidinone derivatives A compound represented by the following formula (12) useful as an intermediate for production of drug or agricultural chemical: ##STR1## (wherein R21 to R25 are each independently a hydrogen atom, a hydroxyl group, a halogen atom, an... | 03/27/2001 |
| 6200967 | Anticoagulant agents This invention relates to a compound of the Formula I X--C(O)--Y--G--R I (wherein X, Y, G and R have the values defined in the description), or a pharmaceutically acceptable salt thereof, processes and intermediates for the preparation of such a compound or s... | 03/13/2001 |
| 6174879 | Aminocyclohexylesters and uses thereof Aminocyclohexylester compounds, including thioesters, are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and com... | 01/16/2001 |
| 6166038 | Aminopyrazole derivatives The present invention relates to a compound represented by the general formula [I]: ##STR1## wherein Ar1 represents an aryl group which may have a substituent selected from the group consisting of a halogen atom and lower alkyl and lo... | 12/26/2000 |
| 6114329 | 5-HT4 receptor antagonists useful in the treatment of gastroinstestinal, cardiovascular and CNS disorders Compounds of formula (I) and pharmaceutically acceptable salts thereof, and the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof: X--CO--CH2 --Z (I) wherein X is a monocyclic or po... | 09/05/2000 |