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A method of swing on a swing is disclosed, in which a user positioned on a standard swing suspended by two chains from a substantially horizontal tree branch induces side to side motion by pulling alternately on one chain and then the other.
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| Number | Title | Issue Date |
| 7368100 | Backbone-substituted bifunctional DOTA ligands, complexes and compositions thereof, and methods of using same Backbone-substituted 1,4,7,10-tetraaza cyclododecane-N,N′,N″,N′″-tetraacetic acid compounds, metal complexes thereof, compositions thereof, conjugates thereof, and methods of use in diagnostic imaging and treatment of a cellular disorder. ... | 05/06/2008 |
| 7358239 | Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives The present invention concerns compounds of formula (I) a stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereof, wherein -Z1-Z2- is... | 04/15/2008 |
| 7211241 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes Described are new cascade polymer complexes, compositions containing them and use of the complexes in diagnosis and therapy, particularly for magnetic resonance imaging and computer tomography imaging. ... | 05/01/2007 |
| 7060818 | Synthesis of macrocyclic tetraamido compounds and new metal insertion process An improved method of synthesizing a macrocyclic tetraamido compound includes protecting the amino portion of an amino carboxylic acid to form a protected amino carboxylic acid; exposing the protected amino carboxylic acid to a first solvent, preferably a hydrocarbo... | 06/13/2006 |
| 7053214 | β-sheet mimetics and composition and methods relating thereto Compounds having the following structure: including pharmaceutically acceptable salts and stereoisomers thereof, wherein A, A′, B, X, Y, R2, R3, R4 and R5 are as defi... | 05/30/2006 |
| 7030238 | C-nitroso compounds and use thereof A C-nitroso compound having a molecular weight ranging from about 225 to about 1,000 (from about 225 to about 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon a... | 04/18/2006 |
| 6987102 | Methods to mobilize progenitor/stem cells Certain nitrogen-containing compounds that bind the chemokine receptor CXCR4 are able to mobilize progenitor and/or stem cells into the peripheral blood to permit harvesting them for stem cell transplantation. ... | 01/17/2006 |
| 6942966 | Methods for processing chemical compounds having reactive functional groups Novel macrocyclic compounds are constructed to include large cyclic structures that are interrupted by at least one ring system. Each interrupting ring system includes two bridgehead atoms. Bridgehead atoms are bonded to one or more bridges that interconnect one or ... | 09/13/2005 |
| 6916805 | Quinoxalinones as serine protease inhibitors This invention discloses quinoxalinones which display inhibitory effects on serine proteases such as factor Xa, thrombin, and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts and prodrugs of the compounds, pharmaceutically acceptable co... | 07/12/2005 |
| 6906189 | Catalysts and methods for catalytic oxidation Catalytic systems and methods for oxidizing materials in the presence of metal catalysts (preferably manganese-containing catalysts) complexed with selected macropolycyclic rigid ligands, preferably cross-bridged macropolycyclic ligands. Included are using these met... | 06/14/2005 |
| 6900222 | Pyrrolidinyl, piperdinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives The present invention concerns compounds of formula (I) a stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereon wherein —Z1—Z2 | 05/31/2005 |
| 6818149 | Ligand and complex for catalytically bleaching a substrate The present invention provides a bleaching composition comprising a [3.3.1] bicyclo compound carrying at least one tertiary amine group the bleaching composition substantially devoid of a peroxygen source. ... | 11/16/2004 |
| 6696435 | Substituted N,N-disubstituted fused-heterocyclo amino compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 02/24/2004 |
| 6670354 | Methods to enhance white blood cell count Methods to elevate white blood cell counts in animal subjects using compounds of formula (1) are disclosed. These compounds have the formula or pharmaceutically acceptable salt thereof wherein Z is a cyclic polyamine containing 9-32 ring members of which 3-8 ... | 12/30/2003 |
| 6656930 | Aralkyl diazabicycloalkane derivatives for CNS disorders Certain aralkyl diazabicycloalkyl compounds are disclosed for treatment of CNS disorders, such as cerebral ischemia, psychosis, and convulsions. For example, compounds of interest are of the formula: ##STR1##... | 12/02/2003 |
| 6576760 | Processes for synthesis of cyclic and linear polyamine chelators containing N-monosubstituted coordinating arms Polyamines containing at least two nitrogen atoms monosubstituted with pendant arms capable of coordinating metal cations, or with precursors of such pendant arms, all nitrogen atoms of the polyamines except two being fully substituted and the remaining t... | 06/10/2003 |
| 6552012 | Heteroaryl diazabicycloalkanes, their preparation and use The present invention relates to novel heteroaryl diazabicycloalkane derivatives represented by general formula (I), any of its enantiomers or any mixture thereof, an N oxide thereof, a pharmaceutically acceptable salt thereof, in a labelled or un-labelle... | 04/22/2003 |
| 6469162 | Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy and diagnosis This invention involves synthesis and use of a class of compounds with chelation affinity and selectivity for first transition series elements. Administration of the free or conjugated compound, or physiological salts of the free or conjugated compound, r... | 10/22/2002 |
| 6455519 | Use of substituted N, N-disubstituted fused-heterocyclo amino compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for t... | 09/24/2002 |
| 6413963 | Reverse-turn mimetics and methods relating thereto Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility in the treatment of cell adhesion-indicated diseases, su... | 07/02/2002 |
| 6395725 | Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals Synthetic low molecular weight catalysts for the dismutation of superoxide are potent analgesics that are effective in elevating the pain threshold in hyperalgesic conditions such as arthritis, and also operate to prevent or reverse tolerance to opioid an... | 05/28/2002 |
| 6369220 | Method of preparing enantiomerically-enriched tetrahydrobenzothiepine oxides A process for preparing enantiomerically enriched tetrahydrobenzothipeine oxides comprises cyclizing an enantiomerically enriched aryl-3-propanalsulfoxide wherein the sulfur atom of the aryl-3-propanalsulfoxide is a chiral center.... | 04/09/2002 |
| 6365583 | Methods to enhance white blood cell count Methods to elevate white blood cell counts in animal subjects using compounds of formula (1) are disclosed. These compounds have the formula Z-linker-Z' (1) or pharmaceutically acceptable salt thereof wherein Z is a cyclic polyamine containing 9-32 ring members of... | 04/02/2002 |
| 6248306 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes Cascade polymer complexes containing a) complexing ligands of general formula I A--{X--[Y--(Z--( W--Kw)z)y ]x }a (I) in which A stands for a nitrogen-containing cascade nucleus of base multiplicity a, X and Y, ind... | 06/19/2001 |
| 6214817 | Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity The present invention relates to compounds which are effective as catalysts for dismutating superoxide and, more particularly, the manganese or iron complexes of substituted, unsaturated heterocyclic pentaazacyclopentadecane ligands which catalytically di... | 04/10/2001 |
| 6207826 | Macrocyclic compounds having nitrogen-containing linkages Novel macrocyclic compounds are constructed to include a ring or ring system having two bridgehead atoms with a bridge extending between the bridgehead atoms. Located in at least the bridge are two or more nitrogenous moieties that are derivatized with ch... | 03/27/2001 |
| 6166200 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes Cascade polymer complexes that contain a) complexing ligands of general formula I A--{X--[Y--(Z--W--KW z)y ]x}a (I), in which A stands for a nitrogen-containing cascade nucleus of base multiplicity a, X and Y, i... | 12/26/2000 |
| 6162912 | Process of preparing tetraacetic acid derivatives The present invention relates to the novel compound, 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one of formula (I), its preparation and the use thereof for the preparation of tetraazamacrocycles . ##STR1##... | 12/19/2000 |
| 6069114 | 2-amino-4-bicycloamino-1,3,5-Triazines, their preparation, and their use as herbicide and plant growth regulators Compounds of the formula (I) and their salts ##STR1## in which R1 to R6, Y1, to Y2, Y3, m and n are as defined in claim 1 are suitable as herbicides and plant growth regulators. They can be prepa... | 05/30/2000 |
| 6063361 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes Cascade polymer complexes having a complexing ligand with at least two different reproduction units and having a complexing agent which is a macrocyclic group having an amide grouping or a linear DTPA-type group having a linkage to the polymer through the... | 05/16/2000 |
| 6048980 | Process of preparing tetraaza tetraacetic acid The present invention relates to the novel compound, 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one of formula (I), its preparation and the use thereof for the preparation of tetraazamacrocycles. ##STR1##... | 04/11/2000 |
| 6028194 | Intermediates The present invention relates to the novel compound, 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one of formula (I), its preparation and the use thereof for the preparation of tetraazamacrocycles and the mono and diacetic acid derivatives. ##STR1##... | 02/22/2000 |
| 6028193 | Method for producing aryl aklyl hydroperoxides A method for producing aryl alkyl hydroperoxides which comprises selectively oxidizing an aryl alkyl hydrocarbon having the formula: ##STR1## wherein P and Q are hydrogen or an alkyl and may be the same or different from each other; x is an integer o... | 02/22/2000 |
| 6020485 | Process for producing tetraazabicyclo monoacetic acid The present invention relates to the novel compound, 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one of formula (I), its preparation and the use thereof for the preparation of tetraazamacrocycles. ##STR1##... | 02/01/2000 |
| 5985869 | Benzoheterocyclic compounds Novel benzoheterocyclic compounds of the formula: ##STR1## wherein R1 is H, halogen, alkyl, optionally substituted amino, alkoxy; R2 is H, halogen, alkoxy, phenylalkoxy, OH, alkyl, optionally substituted amino, carbamoyl-alkoxy,... | 11/16/1999 |
| 5977353 | 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one, a process for the preparation thereof and the use thereof for the preparation of tetraazamacrocycles The present invention relates to the novel compound, 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one of formula (I), its preparation and the use thereof for the preparation of tetraazamacrocycles. ##STR1##... | 11/02/1999 |
| 5958920 | Aralkyl diazabicycloalkane derivatives for CNS disorders Certain aralkyl diazabicycloalkyl compounds are disclosed for treatment of CNS disorders, such as cerebral ischemia, psychosis and convulsions. Compounds of particular interest are of the formula: ##STR1## wherein m is three or four; wherein z is sel... | 09/28/1999 |
| 5874061 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes Cascade polymer complexes that contain a) complexing ligands of general formula I A--{X--Y--(Z--(W--Kw)z)y!x }a, (I) in which A stands for a nitrogen-containing cascade nucleus of base multiplicity a, X and Y, ... | 02/23/1999 |
| 5831088 | Methods to prepare ଲଲ'-dihydroxy meso-substituted chlorins, isobacteriochlorins and bacteriochlorins A ଲ,ଲ'-dihydroxy meso-substituted chlorin, bacteriochlorin or isobacteriochlorin compound having the formula (I) or (II): ##STR1## wherein M is a metal. A novel method for synthesizing the compound of formula (I) or (II) comprises the ste... | 11/03/1998 |
| 5733924 | DC 107 derivatives and treatment methods DC107 derivatives represented by the formula (I): ##STR1## or pharmacologically acceptable slats thereof, wherein R1 is hydrogen, lower alkoxyalkyl, aralkyloxyalkyl, lower alkoxyalkoxyalkyl, lower alkoxyalkoxyalkoxyalkyl, aralkyl, tetrah... | 03/31/1998 |
