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Patent No. 5500234

Crispy Chip Sandwich and Process of Producing a Sandwich Product

A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.

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Class 540/453 - Spiro


Subclass of Class 540 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which include a spiro ring system.
No. of patents: 50
Last issue date: 08/12/2008


1    
NumberTitleIssue Date
7410969Antitumoral analogs of ET-743
Antitumor compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or d...
08/12/2008
7329746Macrocyclic beta-secretase inhibitors for the treatment of Alzheimer's disease
The present invention is directed to compounds of formula I which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is...
02/12/2008
73234557-aryl 1,5-dihydro-4,1-benzoxazepin-2(3)-one derivatives and their use as progesterone receptor modulators
This invention provides progesterone receptor modulators having the structure: wherein R1 to R7, X, and Q are as defined in the specification; or a pharmaceutically acceptable salt thereof. ...
01/29/2008
7294631Substituted 8′-pyri(MI)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-]pyrimidin-6-one derivatives
The invention relates to a dihydrospiro-[cycloalkylamine]-pyrimidone derivative represented by formula (I) or a salt thereof: wherein X, Y, R1, R2, R3, R4, o, m, n, p and q are as defined herein. The invention rela...
11/13/2007
7247629Antitumoral analogs of et-743
Antitumour compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or ...
07/24/2007
7241892Hemisynthetic method and new compounds
Methods are provided for preparing a compound with a fused ring structure of formula (XIV) which comprises one or more reactions starting from a 21-cyano compound of formula (XVI) where typically: R1 is an amidomethylene group or an acyloxymethylene group...
07/10/2007
7202246Spiro-rifamycin derivatives targeting RNA polymerase
Compounds of the current invention relate to rifamycin derivatives having antimicrobial activities, including activities against drug-resistant microorganisms. More specifically, compounds of the current invention relate to a series of novel spiro rifamycin derivati...
04/10/2007
7122677NK1 antagonists
A NK1 antagonist having the formula (I), wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5...
10/17/2006
7122662Tricyclic compound having spiro union
This invention relates to tricyclic compounds having spiro union represented by the following formula (I) or its salt which is useful as a drug, and in particular, as an inhibitor for activated blood coagulation factor X, which can be administered orally and which e...
10/17/2006
6939855Anti-inflammatory compositions and method
The disclosed invention includes pharmaceutical compositions and methods for treating inflammatory conditions, particularly those that are characterized by increased binding of alpha-9 integrin to one or more of its ligands. Also disclosed are methods for selecting ...
09/06/2005
6790954Mutant Actinosynnema pretiosum strain with increased maytansinoid production
A microorganism that is a mutant bacterial strain of the species Actinosynnema pretiosum, designated PF4-4, (ATCC PTA-3921), being capable of producing maytansinoid ansamitocins such as ansamitocin P-3 in improved yield compared to previous known strains, and...
09/14/2004
6545038Heterocyclic metalloprotease inhibitors
The invention provides compounds of formula ##STR1## as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of...
04/08/2003
6281352Macrocyclic compounds as metalloprotease inhibitors
This invention relates to macrocyclic molecules which inhibit metalloproteinases, including aggrecanase, and the production of tumor necrosis factor (TNF). In particular, the compounds are inhibitors of metalloproteinases involved in tissue degradation an...
08/28/2001
6265572Pyrrolidincarbonylamino cyclic disulfide anti-inflammatory agents
Compounds of the formula: ##STR1## are described which have activity as anti-inflammatory agents. Cyclic disulfide compounds are provided which inhibit of binding of cells to endothelium. Such compounds are useful for treating inflammatory diseases, ...
07/24/2001
6207668Substituted pyridines/pyrimidines, their preparation, and their use as pesticides
The present invention relates to novel substituted pyridines/pyrimidines of the formula I ##STR1## where A is CH or N; X is NH, oxygen or S(O)q where q is 0, 1 or 2; Y is a direct bond or CH2 ; Z is oxygen, NR7 or S(O)
03/27/2001
6180619Prenyl transferase inhibitors
A family of compounds capable of inhibiting the activity of prenyl transferases. The compounds are covered by the four following formulas ##STR1## Each of the R groups is defined in the disclosure....
01/30/2001
6124453Macrolides
A novel class of macrolides in which i) positions 2 to 6 inclusive of the macrocyclic ring are provided by a piperidazinyl carboxylic acid residue; and/or ii) positions 7 to 9 inclusive of the macrocyclic ring are provided by an aromatic ଱-amino acid res...
09/26/2000
6100394Long-lived homogenous oxidation catalysts
A robust chelate complex is provided having the formula: ##STR1## wherein: M is a metal, preferably a transition metal; Z is an anionic donor atom, three of which are nitrogen, and the other is oxygen; L1 is a labile ligand; Ch1...
08/08/2000
5952320Macrocyclic inhibitors of matrix metalloproteinases and TNF଱ secretion
Macrocyclic compounds of formula ##STR1## are potent inhibitors of matrix metalloproteinase and are useful in the treatment of diseases in which matrix metalloproteinase play a role. Also disclosed are matrix metalloproteinase inhibiting compositions...
09/14/1999
5877312Method for preparing alkylating agents for their use for alkylating cyclic ureas
This invention relates to methods for preparing alkylating agents and use of the agents prepared. In particular, this invention relates to preparation methods for hydroxy halide and organooxy halide alkylating agents and their use for alkylating cyclic ur...
03/02/1999
5856476Processes for preparing azepiones useful as intermediates in the preparation of inhibitors of angiotensin converting enzyme and neutral endopeptidase
Processes are disclosed for preparing the azepine intermediates of the formula ##STR1## These intermediates can be reacted with acylmercaptocarboxylic acids of the formula ##STR2## to give the pharmaceutically active products....
01/05/1999
5726307Benzo-fused lactams promote release of growth hormone
There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat pr...
03/10/1998
5721362Process for producing ecteinascidin compounds
The present invention is directed to a synthetic process for the formation of ecteinascidin compounds and related structures, such as the saframycins. In one particularly preferred embodiment, the present invention provides a synthetic route for the forma...
02/24/1998
5627283Amidinophenylalanine derivatives, a process for the preparation thereof, use thereof and agents containing these as anticoagulants
Amidinophenylalanine derivatives of the formula I ##STR1## the synthesis of these compounds, the use thereof and pharmaceutical agents which contain these compounds are described....
05/06/1997
5457114Amidinophenylalanine derivatives, a process for the preparation thereof, use thereof and agents containing these as anticoagulants
Amidinophenylalanine derivatives of the formula I ##STR1## the synthesis of these compounds, the use thereof and pharmaceutical agents which contain these compounds are described....
10/10/1995
5362726Compound and method of treatment for falciparum malaria
This invention deals with the spirononacyclic indoloquinoline alkaloid known as cryptospirolepine and its use as an anti-malarial....
11/08/1994
5326782Salts derived from 26-(dialkylaminoalkylsulphonyl)pristinamycin IIB
Di-p-toluoyl tartrate, di-t-butylacetyl tartrate, di-butyryl tartrate and di-i-valeryl tartrate of (dialkylamino-2 alkyl)sulphonyl-26 pristinamycin IIB having general formula (I) wherein Alk represents a straight or branched alkylene radical an...
07/05/1994
52448885-HT selective agents
Substituted 8-alkoxy-1,2,3,3a,8,8a-hexahydroindeno[1,2-c]pyrroles; 5-alkoxy-2,3,4,4a,9,9a-hexahydro-1-H-indeno[2,1-c]pyridines; and 9-alkoxy-2,3,3a,4,5,9a-hexahydro-1H-benz[e]isoindoles are selective 5-HT receptor agents and are thus useful in the treatme...
09/14/1993
5242911Bridged bicyclic imides as anxiolytics and antidepressants
A series of bridged bicyclic imide compounds having a 4-(4-[2-pyrimidinyl]-1-piperazinyl)butyl group attached to the imide nitrogen are useful for alleviating the symptoms of anxiety and depression in human subjects....
09/07/1993
5149823Sulfonamide substituted spirodilactams
A novel class of sulfonamoyl-substituted 1,6-diaza[4.4]spirodilactams, having a sulfonamoyl substituent on the hydrocarbyl group attached to each spiro ring nitrogen atom, is useful for the preparation of polymers, including polyamides and as latent curin...
09/22/1992
5141930Fused thiophene compounds and uses thereof
A fused thiophene compound of the formula: ##STR1## or a pharmaceutically acceptable acid addition salt thereof. In the above formula, one of E1, E2 and E3 is sulfur atom and other two of them are C--R1 and...
08/25/1992
5128466Cyclic compounds for complexing with cations
Cyclic molecules having oriented groups are capable of forming stable complexes with cations....
07/07/1992
4771044Tetraoxo compounds and pharmaceutical compositions
Tetraoxo compounds of the Formula (I) ##STR1## wherein R1 is an alkyl, alkenyl, phenylalkyl or cycloalkylalkyl group, R2 and R3 are each independently an alkyl or phenyl group or together denote an alkylene group, W i...
09/13/1988
4764512Benzodiazinone-pyridone compounds, cardiotonic compositions including the same, and their uses
This invention relates to substituted benzodiazinone-pyridone compounds and their use as cardiotonic agents including methods for increasing cardiac contractility, pharmaceutical compositions including the same and methods for the preparation thereof....
08/16/1988
4709027Bicyclic spirosulfonimides with psychotropic activity
There are disclosed compounds of the formula ##STR1## wherein R1 and R2 are each, independently, hydrogen or lower alkyl, or R1 and R2 taken together represent ##STR2## A is O or NR3 ; B is ...
11/24/1987
4372961Derivatives of rifamycins, their preparation and pharmaceutical compositions thereof
The present invention provides compounds of the general formula: ##STR1## wherein Y is a hydrogen atom or an acetyl radical, R is a hydrogen atom, a straight-chained or branched, saturated or unsaturated aliphatic hydrocarbon radical containing up to...
02/08/1983
4309541Piperidinyl-lactams
N-[1-(4-amino-2-quinazolinyl)-3 or 4-piperidinyl]-lactams, e.g., those of the formula ##STR1## and salts thereof are antihypertensive agents....
01/05/1982
4297497Synthesis of 2-keto-1,4-diazacycloalkanes
Several novel syntheses have been discovered for preparation of 2-keto-1,4-diazacycloalkanes and their derivatives. Trans isomers of polysubstituted quinoxalin-2-ones may now be prepared....
10/27/1981
4261990N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
N-(diphenylmethoxy-mono- or bicyclic-alkyleneiminoalkyl)-dicarboximides, e.g. those of the formula ##STR1## A=aliphatic or cycloaliphatic radical R,R'=H, alkyl, halogen or CF3 R"=H or both are ethylene q=2-4 and salts thereof are antiallergics ...
04/14/1981
4255429N-Quinazolinylpiperidinyl-lactams
N-[1-(4-amino-2-quinazolinyl)-3- or 4-piperidinyl]-lactams, e.g., those of the formula ##STR1## and salts thereof are antihypertensive agents....
03/10/1981
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