Bizarre Patents
A sealed crustless sandwich for providing a convenient sandwich without an outer crust which can be stored for long periods of time without a central filling from leaking outwardly.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7807826 | Purification of a crude lactam mixture by means of melt crystallization The present invention provides a method for purifying laurolactam from a crude lactam mixture. In the method of the present invention, laurolactam is selectively crystallized by melt crystallization with controlled cooling of the crude lactam mixture. ... | 10/05/2010 |
| 7579462 | Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins Efficient chemical processes for preparing high yields, purities, and different polymorphic forms of 17-allyl amino geldanamycin (17-AAG) and other ansamycins are described and claimed. ... | 08/25/2009 |
| 7402675 | Process for the synthesis of amine ethers from secondary amino oxides An amine ether of formula A wherein a is 1 or 2; and when a is 1, E is E′; when a is 2, E is L; E′ is C1-C36 alkyl; C3-C18 alkenyl; C2 | 07/22/2008 |
| 7323563 | Hydroxamic acid derivatives as antibacterials A method for the treatment of bacterial infections in humans and non-human mammals, which comprises inhibiting bacterial growth by administering to a subject an antibacterially effective dose of a compound of formula (I) or a pharmaceutically or veterinarily accepta... | 01/29/2008 |
| 7320974 | Cytoskeletal active compounds, compositions and use The present invention is directed to synthetic cytoskeletal active compounds that are related to natural Latrunculin A or Latrunculin B. The present invention is also directed to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable... | 01/22/2008 |
| 7244594 | Microbial transformation method for the preparation of an epothilone A microbial method for the preparation of an epothilone containing a terminal hydroxyalkyl group, comprising contacting at least one epothilone having a terminal alkyl group with an enzyme or microorganism capable of catalyzing the selective hydroxylation of said al... | 07/17/2007 |
| 7192940 | Ether compounds The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a compo... | 03/20/2007 |
| 7153978 | Method for purifying N-methyl-2-pyrrolidone A method for purifying N-methyl-2-pyrrolidone is disclosed. The method comprises treating N-methyl-2-pyrrolidone with an alumina that desorbs less than 100 μmol/g of isobutylene between 225° C. and 400° C. in a standard tert-butyl alcohol dehydration test. The me... | 12/26/2006 |
| 7125893 | 6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations This invention describes the new 6-alkenyl- and 6-alkinyl-epothilone derivatives of general formula I in which R1a, R1b, R2a, R3a, R3b, R4, R... | 10/24/2006 |
| 7122677 | NK1 antagonists A NK1 antagonist having the formula (I), wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5... | 10/17/2006 |
| 7067544 | Epothilones C, D, E and F, preparation and compositions The present invention relates to epothilones C, D, E and F, their preparation and their use for the production of therapeutic compositions and compositions for plant protection. ... | 06/27/2006 |
| 7026310 | Heteroaryl derivatives and their use as medicaments The invention relates to novel quinoline derivatives of the formula 1, to their preparation and to their use as medicaments, in particular for treating tumors. ... | 04/11/2006 |
| 7022844 | Amide-based compounds, production, recovery, purification and uses thereof Methods are disclosed of producing and purifying at least one amide. In accordance with one of the methods disclosed herein, the at least one amide is produced by providing an organic liquid comprising at least one oxime, providing at least one catalyst, adding the ... | 04/04/2006 |
| 6984734 | Cyclo[n]pyrroles and methods thereto The present invention provides an oxidative coupling procedure that allows efficient synthesis of novel cyclo[n]pyrrole macrocycles. Therefore, the present invention provides cyclo[n]pyrroles where n is 6, 7, 8, 9, 10, 11, or 12, and derivatives, multimers, isomers,... | 01/10/2006 |
| 6962992 | Crown ether derivatives The invention describes crown ether chelators, including crown ethers having the formula and aza-substituted and thia-substituted analogs thereof. These crown ethers are substituted by a dye moiety, a chemically reacti... | 11/08/2005 |
| 6936447 | Autoinducer molecule Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, for Pseudomonas aeruginosa are described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the ... | 08/30/2005 |
| 6906188 | Method for synthesizing epothilones and epothilone analogs A method for making epothilones and epothilone analogs is described, as are novel compounds made by the method. Exemplary novel compounds include those according to the formula: With respect the formula, G is selected ... | 06/14/2005 |
| 6900328 | Process for the synthesis of amine ethers from secondary amino oxides An amine ether of formula (A) wherein a is 1 or 2; and when a is 1, E is E′; when a is 2, E is L; E′ is C1-C36 alkyl; C3-C18 alkenyl; C2-C18 alkinyl; C5-C18 cycloalkyl; C | 05/31/2005 |
| 6890921 | Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia This invention relates to a series of arylsubstituted piperazines, of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibi... | 05/10/2005 |
| 6852713 | Lactam derivatives and methods of their use Lactam derivatives of the general formula are disclosed. Pharmaceutical compositions containing the compounds and methods for their use are also disclosed. ... | 02/08/2005 |
| 6790953 | Ether compounds The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a compo... | 09/14/2004 |
| 6747021 | Cryptophycin compound The present invention provides antitumor methods, formulations, and compounds comprising a cryptophycin. ... | 06/08/2004 |
| 6525197 | Methods for preparing macrocyclic products by ring-closing diyne metathessis The present invention relates to methods for preparing macrocyclic products having 9 or more ring atoms by ring-closing diyne metathesis of suitable diyne substrates. The diyne substrates can be converted into cycloalkynes or into cycloalkadiynes by cyclo... | 02/25/2003 |
| 6489314 | Epothilone derivatives and methods for making and using the same The present invention relates to 16-membered macrocyclic compounds. In one aspect of the present invention, compounds of the formula ##STR1## are provided wherein: R1, R2, R3, and R5 are each independently hydrogen, ... | 12/03/2002 |
| 6482944 | Processes for preparing tertiary aminoalkylorganometallic compounds Processes for the preparation of haloalkylamines and tertiary aminoalkylorganometallic compounds are disclosed. The haloalkylamines can be prepared by direct reaction of an amine with an , ω-dihaloalkane or an , ω-dihaloalkene. Tertiary ... | 11/19/2002 |
| 6468406 | Anion-complexing compound, method of preparing the same, an ion-selective membrane and a sensor provided with such a compound or membrane The invention is directed to an anion-complexing compound with the formula I ##STR1## wherein R1 is a six-membered ring, Y' is --NHC(X)NH--, and Y" is selected from the group consisting of --NHC(X')--, --C(X')NH--, and --NHC(X') NH--; and wherein X a... | 10/22/2002 |
| 6384035 | Heterocycles useful in the treatment of benign prostatic hyperplasia This invention relates a to a series of heterocyclic substituted piperazines of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to ... | 05/07/2002 |
| 6362333 | Method for simultaneously producing a cyclic lactam and a cyclic amine A cyclic lactam and a cyclic amine are coproduced by coreacting an aliphatic alpha, omega-diamine and an aliphatic alpha, omega-aminonitrile with water in the gas phase in the presence of a heterogeneous catalyst.... | 03/26/2002 |
| 6362332 | Coproduction of a cyclic lactam and a cyclic amine A cyclic lactam and a cyclic amine are coproduced by reacting an aliphatic alpha, omega-diamine with water in the gas phase in the presence of a heterogeneous catalyst.... | 03/26/2002 |
| 6313109 | Prenyl transferase inhibitors A family of compounds capable of inhibiting the activity of prenyl transferases. The compounds are covered by the four following formulas ##STR1## Each of the R groups is defined in the disclosure.... | 11/06/2001 |
| 6281352 | Macrocyclic compounds as metalloprotease inhibitors This invention relates to macrocyclic molecules which inhibit metalloproteinases, including aggrecanase, and the production of tumor necrosis factor (TNF). In particular, the compounds are inhibitors of metalloproteinases involved in tissue degradation an... | 08/28/2001 |
| 6207824 | Purification of N-substituted lactams A process for reducing the amine content of amine-contaminated N-substituted lactams comprises treating the contaminated N-substituted lactams with an acid macroporous cation exchanger.... | 03/27/2001 |
| 6180113 | Pharmaceutical agents that contain perfluoroalkyl-containing metal complexes Pharmaceutical agents that contain perfluoroalkyl-containing metal complexes are useful in tumor therapy and interventional radiology.... | 01/30/2001 |
| 6174879 | Aminocyclohexylesters and uses thereof Aminocyclohexylester compounds, including thioesters, are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and com... | 01/16/2001 |
| 6143739 | Basic proline-amide derivatives of GE 2270 and GE 2270-like antibiotics The present invention refers to basic amides derivatives of GE 2270 and GE 2270-like antibiotics of general formula (1), wherein the group GE represents the antibiotic core molecule. The amide derivatives of antibiotic GE 2270 of formula (I) are antimicro... | 11/07/2000 |
| 6100394 | Long-lived homogenous oxidation catalysts A robust chelate complex is provided having the formula: ##STR1## wherein: M is a metal, preferably a transition metal; Z is an anionic donor atom, three of which are nitrogen, and the other is oxygen; L1 is a labile ligand; Ch1... | 08/08/2000 |
| 6100396 | Method for purifying lactams A method for purifying lactams by liquid-liquid extraction and/or processing with an ion exchange resin is disclosed. The method is useful for purifying lactams produced by the cyclising vapour-phase hydrolysis of an aliphatic aminonitrile, and comprises ... | 08/08/2000 |
| 6080771 | DC107 derivatives DC107 derivatives represented by formula (I) or pharmaceutically acceptable salts thereof which have antimicrobial activity and antitumor activity are provided: ##STR1## wherein R1 represents CO(CR4A R4B)n1... | 06/27/2000 |
| 6071915 | Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia This invention relates to a series of arylsubstituted piperazines, of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the &... | 06/06/2000 |
| 6054579 | Synthesis of substituted lactams The invention relates to an efficient and facile method for the preparation of substituted lactams, as described herein. The method comprises reacting a difunctional component containing an activated carbon, an amine capable of forming an imine with the a... | 04/25/2000 |
