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Class 540/38 - Chalcogen bonded directly at the 11-position of the cyclopentanohydrophenanthrene ring system


Subclass of Class 540 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which chalogen (i.e., oxygen, sulfur, selenium
No. of patents: 14
Last issue date: 03/16/1993


NumberTitleIssue Date
51946029଱-hydroxy-17-methylene steroids, process for their preparation and their use in the preparation of corticosteroids
New 9଱-hydroxy-17-methylene steroids are prepared by the introduction of a substituted 17-methylene group in 9଱-hydroxyandrost-4-ene-3, 17-dione. The resulting compounds are useful starting compounds in the synthesis of corticosteroids....
03/16/1993
4767856Preparation of caprolactam from 6-aminocaproic acid, esters and amides
In an improved process for preparing caprolactam by heating 6-aminocaproic acid, an ester or amide or mixture thereof in the presence of an inert reaction medium which is liquid under the reaction conditions and has a boiling point above that of caprolact...
08/30/1988
4710495Soft steroids having anti-inflammatory activity
Novel soft steroid anti-inflammatory agents, said agents being esters or thioesters of 17଱-alkoxy-11ଲ-hydroxyandrost-4-en-3-one-17ଲ-carboxylic acids, pharmaceutical compositions containing said agents, novel chemical intermediates u...
12/01/1987
4390533Steroids and process for preparing the same
The present invention relates to 2-chloro-6ଲ-fluoro-pregna-1,4-diene-3,20-diones having good anti-inflammatory activity, to processes for their preparation and pharmaceutical compositions thereof....
06/28/1983
4357279Preparation of corticoids from 17-keto steroids
A process for the preparation of corticoids (XI) which comprises reacting a protected 17-keto steroid (II) with a metallated 1,2-dihaloethene (III)....
11/02/1982
4303654Novel 21-chloro-20-acetylenic steroids
Novel 21-chloro-20-acetylenic steroids of the formula ##STR1## wherein R1 is alkyl of 1 to 3 carbon atoms, R is selected from the group consisting of hydrogen and acyl of an organic carboxylic acid of 1 to 18 carbon atoms, X is selected fr...
12/01/1981
4275061Steroids and process for preparing the same
The present invention relates to 2-chloro-6ଲ-fluoropregna-1,4-diene-3,20-diones having good anti-inflammatory activity, to processes for their preparation and pharmaceutical compositions thereof....
06/23/1981
423329611ଲ-Substituted-Ɗ4,9 -estradienes
Novel steroids of the formula ##STR1## wherein R1 is linear or branched alkyl of 1 to 12 carbon atoms, unsaturated alkyl of 2 to 8 carbon atoms optionally substituted, optionally substituted aryl of 6 to 12 carbon atoms, optionally su...
11/11/1980
4226862Steroids and process for preparing the same
Novel steroids are described together with processes of making them and pharmaceutical compositions containing them. The steroids have pharmaceutical activity, especially anti-inflammatory activity. They are all 2-Bromo-6ଲ-fluoro-pregna-1,4-diene-3,...
10/07/1980
4216159Synthesis of 16-unsaturated pregnanes from 17-keto steroids
17-Keto steroids (I) in their protected form (IIa or IIb) are reacted with a metalated olefin (VI) to give a 21-aldehyde (IV) which is readily transformed to a 16-unsaturated pregnane (V) which is useful in the production of commercially important substit...
08/05/1980
4155923Process for the preparation of 17ଲ-hydroxy-20-alkoxypregnane-21-oic acid derivatives
A process for the preparation of 17ଲ-hydroxy-20-alkoxypregnane-21-oic acid derivatives of the formula ##STR1## WHEREIN R1 is methyl or ethyl; R2 is hydrogen or methyl, either being in the ଱-or ଲ-position; R
05/22/1979
4031074Process for the preparation of 11ଲ-hydroxy-18-alkyl-estrane compounds
The present invention relates to a novel process for the preparation of 11ଲ-hydroxy-18-alkyl-estrane compounds by reacting an 11ଲ-hydroxy-13-methyl-gonane compound with an excess of an acylhypoiodite to give an estrano-18,11ଲ-lactone, re...
06/21/1977
3998813Process for the preparation of 11ଲ-hydroxy-18-alkyl-estrane compounds
The present invention relates to a novel process for the preparation of 11ଲ-hydroxy-18-alkyl-estrane compounds by reacting an 11ଲ-hydroxy-13-methyl-gonane compound with an acylhypoiodite to give an 11ଲ-hydroxy-13-iodomethyl-gonane compou...
12/21/1976
3960842Process for the preparation of 17ଲ-oxalyl steroids
20-Cyano-17଱-H steroids having as the 17-position substituent the group ##EQU1## wherein R is H, alkyl of 1-8 carbon atoms or benzyl, having a 13-methyl or 13-ethyl group and which are unsubstituted or substituted with an ଱-methyl gr...
06/01/1976
 
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