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| Number | Title | Issue Date |
| 6262042 | 17ଲ-amino and hydroxylamino-11ଲ-arylsteroids and their derivatives having agonist or antagonist hormonal properties The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.... | 07/17/2001 |
| 6117994 | Intermediates for 16ଲ-methyl steroids A new process for the preparation of 16ଲ-methyl-steroids of the formula ##STR1## and novel intermediates.... | 09/12/2000 |
| 5591733 | Methods, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, insomnia and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-aminobutyric acid receptor-chloride ionoph... | 01/07/1997 |
| 5438134 | Process for the production of unsaturated 17 -cyanomethyl-17 ଲ- h The unsaturated 17-cyanomethyl-17ଲ-hydroxy steroids of the formula I, ##STR1## in which R1 =Me, Eth; R2 =H, Me; R3 =H, OH, an acetoxy or alkoxy group; R4 =H, R5 =OH, an acetoxy, alko... | 08/01/1995 |
| 5359054 | Initial compounds for the production of 10ଲ-H-steroids and a process for the production of these initial compounds The invention includes compounds of the following formula ##STR1## where A and B either A and B form an additional double bond and D is a hydrogen atom or B and D form an additional double bond and A is a hydrogen atom and the other variables are as ... | 10/25/1994 |
| 5194602 | 9-hydroxy-17-methylene steroids, process for their preparation and their use in the preparation of corticosteroids New 9-hydroxy-17-methylene steroids are prepared by the introduction of a substituted 17-methylene group in 9-hydroxyandrost-4-ene-3, 17-dione. The resulting compounds are useful starting compounds in the synthesis of corticosteroids.... | 03/16/1993 |
| 5003063 | Conversion of steroidal 17-cyanohydrins to corticoids The invention involves a two step chemical transformation of a steroidal 17-cyanohydrin (II) ##STR1## to a 17-hydroxy-21-halo-20-keto steroid (IV) ##STR2## intermediate which can readily be converted to pharmaceutically useful cortic... | 03/26/1991 |
| 4954490 | 11 ଲ-substituted progesterone analogs A 11ଲ-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R1 is H, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, OH, OC(O)CH3, or OC(O)R5, wherein R5 is C2-... | 09/04/1990 |
| 4780461 | 13-alkyl-gonanes, their production, and pharmaceutical preparations containing same 13-alkylgonanes of formula I ##STR1## where R is an acyl radical with as many as 10 C-atoms, and X is an oxygen atom or the grouping N--OH, have a strong antigestagenic effect and can be used for postcoital fertility control.... | 10/25/1988 |
| 4710495 | Soft steroids having anti-inflammatory activity Novel soft steroid anti-inflammatory agents, said agents being esters or thioesters of 17-alkoxy-11ଲ-hydroxyandrost-4-en-3-one-17ଲ-carboxylic acids, pharmaceutical compositions containing said agents, novel chemical intermediates u... | 12/01/1987 |
| 4647410 | Novel 17-substituted steroids Novel 17-(formamidosulfonylmethylene)-steroids of the formula ##STR1## useful as intermediates for the novel 17-(isocyanosulfonylmethylene)-steroids of the formula ##STR2## which are useful intermediates for 21-hydroxy-20-keto-Ɗ16 ... | 03/03/1987 |
| 4634695 | Steroid derivatives Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R1 is an organic radical of 1 to 18 carbon atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with the... | 01/06/1987 |
| 4609651 | 11ଲ-arylestradienes, their production, and pharmaceutical preparations containing same 11ଲ-Arylestradienes of general Formula I are disclosed ##STR1## wherein R2 is a hydrogen atom, a methyl group, or an ethyl group, R3 is a hydrogen atom or an acyl group, R1 and A-B have various meanings, which possess ant... | 09/02/1986 |
| 4585590 | Cyanohydrin process Using cyanohydrin intermediates, 17-keto steroids are transformed to corticoids and 17-acyl progesterones.... | 04/29/1986 |
| 4565656 | Preparation of 17ଲ-hydroxyacetyl-17-ol-steroids A novel process for the preparation of 17ଲ-hydroxyacetyl-17-ol-steroids of the formula ##STR1## wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted with halogen or ... | 01/21/1986 |
| 4548749 | Process for the preparation of 21-hydroxy-20-keto-Ɗ16 -steroids and new intermediate compounds formed in this process A novel process for the preparation of 21-hydroxy-20-keto-Ɗ16 -steroids comprising reacting a 17-(isocyanosulfonylmethylene)-steroid with an aldehyde and an alcohol to form a 17-(2-alkoxy-3-oxazolin-4-yl)-Ɗ16 -steroid and subjectin... | 10/22/1985 |
| 4548748 | Cyanohydrin process Using cyanohydrin intermediates, 17-keto steroids are transformed to corticoids and 17-acyl progesterones.... | 10/22/1985 |
| 4495102 | Aminoalkyl steroids Compounds of Formula I and II are useful as potent antiarrythmic agents without significant effect on cardiac output and blood pressure.... | 01/22/1985 |
| 4147695 | 11ଲ-Substituted-Ɗ9 -steroids Novel 11ଲ-substituted-Ɗ9 -ene-5-ols of the formula ##STR1## wherein K is a blocked ketone in the form of a ketal, thio-ketal or methyloxime, X is a pentagonal or hexagonal ring optionally substituted, R1 is selecte... | 04/03/1979 |
| 4110325 | 21-(Acetyloxy)-3-oxo-24-norchola-4,20(22)-diene-23-nitrile and intermediates thereto Preparation of 21-(acetyloxy)-3-oxo-24-norchola-4,20(22)-diene-23-nitrile; its diuretic, antiulcerogenic, and antiviral utility; and intermediates whereby the preparation can be variously effected are disclosed.... | 08/29/1978 |
| 4081537 | Ɗ15 -Steroids and pharmaceutical compositions thereof Ɗ15 -Steroids of the formula ##STR1## wherein R1 is a hydrogen atom, trialkylsilyl or acyl; R2 is ethynyl, chloroethynyl or propinyl; and X is an oxygen atom, ##STR2## or NOR4 wherein R3 is... | 03/28/1978 |
| 4059575 | Process for the preparation of 17(20)ene-21-steroid aldehydes There is disclosed a process for the efficient conversion of 17--ethynyl 17-ଲ- hydroxy steroids into the corresponding 17(20) ଲ-unsaturated 21-steroid aldehydes. The process comprises the sequential steps of reacting the ethynyl ... | 11/22/1977 |
| 3997664 | Substituted carbinol derivatives The compounds are steroidal 17-propadienyl carbinols and derivatives thereof. The compounds have estrogenic/progestational activity.... | 12/14/1976 |
| 3944576 | Novel steroids of the oestrane series substituted in 7-position The invention relates to novel 7-substituted-steroids of the oestrane series of the general formula: ##SPC1## In which Ring A including carbon atom 6 is ##SPC2## R1 = an alkyl group with 1-4 C-atoms, R2 = oxygen or (Y)(ଲ... | 03/16/1976 |
