3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 7138427 | 5-β-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed ... | 11/21/2006 |
| 5252729 | Extraction of compounds from plant materials using supercritical fluids The present invention is directed toward a process for extracting compounds from plant material, comprising a) contacting hydrolyzed plant material with a supercritical fluid and optionally with a co-solvent and p1 b) recovering the compound from the supe... | 10/12/1993 |
| 5017562 | Crystalline saponin-containing complex A composition of matter is provided comprising a crystalline saponin-containing complex, wherein said crystalline complex is derived from a steroidal-saponin-containing plant material. Said crystalline complex is derived from a saponin-containing plant ma... | 05/21/1991 |
| 4057541 | Method for isolation of 3-hydroxy steroids and 3-keto steroids An improved process for isolating 3-hydroxy steroids and 3-keto steroids from mixtures thereof with lipids by dissolving the mixtures in an organic solvent, mixing the dissolved mixture with a metal salt to form insoluble adducts of the steroids, separati... | 11/08/1977 |
| 3981867 | Process for obtaining sapogenin particularly hecogenin from plant material such as agave sisalana leaves An improved process for obtaining sapogenins, mainly hecogenin, from plants. This improved process involves collecting, undiluted, the juice of sisal leaves and subjecting this juice to acid hydrolysis at elevated temperature and pressure. The sapogenin f... | 09/21/1976 |
| 3935194 | Separation of hecogenin-tigogenin mixtures A process for separating hecogenin-tigogenin mixtures which involves acetylating the mixed genins, then solvent recrystallization separation of the mixed genin acetates, crystallizing out hecogenin acetate from a non-polar solvent, tigogenin acetate from ... | 01/27/1976 |