Class 536/7.5 - Purification or recovery

Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Processes which include separating the compound from impurities
No. of patents: 24
Last issue date: 11/20/2007

Number	Title	Issue Date
7297682	Diphosphate salt of a 4″—substituted-9-deoxo-9 A—AZA—homoerythromycin derivatives and its pharmaceutical composition This invention relates to a novel crystalline diphosphate salt of (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopryanosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideo...	11/20/2007
7071170	Macrolide antibiotics This invention relates to compounds of the formula wherein a, R1, R2, R3, R4, R5, R6 and X are each as defined above, and to pharmaceutically acce...	07/04/2006
6861412	Diphosphate salt of A 4″-substituted-9-deoxo-9A-AZA-9A-homoerythromycin derivative and its pharmaceutical composition This invention relates to a novel crystalline diphosphate salt of (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-dideoxy-3-C-methyl-3-o-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopryanosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideo...	03/01/2005
6809188	Method of preparing clarithromycin Clarithromycin can be easily prepared by reacting erythromycin A N-oxide with a methylating agent to obtain 6-O-methylerythromycin A N-oxide; and treating 6-O-methylerythromycin A N-oxide obtained above with a reducing agent in a high yield. ...	10/26/2004
6204368	Process for the purification of roxithromycin A process for the purification of roxithromycin, an antibiotic for therapeutic purposes, in which the purification is carried out by the dissolution or suspension of the product in methanol followed by cooling. Purification may also be obtained by additio...	03/20/2001
6162794	Erythromycin derivatives The invention relates to compounds of the formula: ##STR1## and to pharmaceutically acceptable salts thereof, wherein R and Z are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I, meth...	12/19/2000
6054435	6-O-substituted macrolides having antibacterial activity The instant invention provides novel macrolide compounds and compositions useful in treating bacterial infections. Also provided are processes for preparing same....	04/25/2000
5919916	6-O-alkyl derivatives of erythronolide B Novel 6-O-alkyl derivatives of erythronolide B are provided. A process for the preparation of 6-O-alkyl derivatives of erythronolide B using erythromycin B is also provided. A process for preparing 6-O-alkyl derivatives of erythromycin C using novel 6-O-a...	07/06/1999
5869629	Synthesis of 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythromycin A 11,12 Hydrogenorthoborate dihydrate and a process for the preparation of azitromicin dihydrate The preparation of azitromycin dihydrate from 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythromycin A 11,12-hydrogenorthoborate, obtained by a step by step process starting from 9-deoxo-6-deoxy-6,9-epoxy-9,9a-dihydro-9a-azahomoerythromycin A is a ...	02/09/1999
5864023	3'-N'oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives The disclosed invention relates to novel 3'-N-O, 9-O-oxime protected, 6-O-alkyl erthyromycin derivatives, a process of preparing the same. The invention also relates to a process of preparing 6-O-alkyl erythromycin A by eliminating the 3'-N-oxide group an...	01/26/1999
5854219	9-N-ethenyl derivatives of 9(S)-erythromycylamine The invention relates to 9-N-ethenyl derivatives of 9 (S)-erythromycylamine, new semisynthetic antibiotics of the macrolide class of the general formula (I) ##STR1## wherein R1 and R2 are the same or different and represent ...	12/29/1998
5844105	Preparation of crystal form II of clarithromycin The present invention provides a process for the preparation of 6-O-methylerythromycin A Form II comprising converting erythromycin A to 6-O-methylerythromycin A and treating the 6-O-methylerythromycin A with a number of common organic solvents or mixture...	12/01/1998
5840861	A83543 compounds and process for production thereof New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 c...	11/24/1998
5670364	A83543 compounds and process for production thereof New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 c...	09/23/1997
5670486	A83543 compounds and process for production thereof New A83543 components, including fermentation products A83543K, A83543O, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 c...	09/23/1997
5670632	Process for obtaining an isoflavone concentrate from a soybean extract A process is disclosed for recovering isoflavones from a soy extract comprises: dripping the soy extract dissolved in the aqueous solvent through a chromatographic column from top to bottom packed with a ground highly polar cationic exchange resin contain...	09/23/1997
5552533	Preparation of (8S)-8-fluoroerythromycins with N-F fluorinating agents (8S)-8-fluoroerythromycins are prepared by reacting 8,9-anhydroerythromycin 6,9-hemiacetals or an N-oxide thereof with a carboxylic acid and an N-F fluorinating agent. The anhydro starting material may be prepared in situ from erythromycins or an N-oxide ...	09/03/1996
5441939	3"-desmethoxy derivatives of erythromycin and azithromycin A compound having the formula ##STR1## wherein Z is CH2 --N(CH3), N(CH3)--CH2, or ##STR2## R1 and R2 are selected from 1) one of R1 and R2 is OH and the othe...	08/15/1995
5227295	Process for isolating A83543 and its components An improved process for isolating A83543 factors from fermentation broth in which they are produced which comprises: a) adding an approximately equal volume of a water miscible, polar organic solvent to the fermentation broth, including the biomass thereof; b)...	07/13/1993
4673736	Process for the preparation of (8S)-8-fluoroerythromycins For the synthesis of (8S)-8-fluoroerythromycins the corresponding 8,9-anhydroerythromycins 6,9-hemiketal are directly fluorinated with perchloryl fluoride....	06/16/1987
4672109	Method for selective methylation of erythromycin A derivatives A method for the selective methylation of a hydroxy group at the 6-position of an erythromycin A derivative which comprises converting an erythromycin A derivative into an erythromycin A 9-oxime derivative, and reacting the resulting ethythromycin A 9-oxi...	06/09/1987
4594187	Process for preparing antibiotic L 17054 The present invention is directed to a chemical process for preparing the antibiotic substance denominated antibiotic L 17054 and its pharmaceutically acceptable salts by selectively hydrolyzing teicoplanin or a factor or component thereof with a concentr...	06/10/1986
4568740	Process for purifying Tylosin Disclosed is a process for purifying Tylosin by selective adsorption of the fermentation broth previously brought to 7.5-10.0 pH on polymeric resins and by subsequent deadsorption of the purified product with a aqueous-alcoholic or aqueous-acetonic soluti...	02/04/1986
3986927	Process for the purification and sterilization of acidophilic biologicals by extreme acidification at cold temperatures Methods of sterilizing biologicals in which the biologicals are acidified to a pH of not higher than about 1.0, preferably 0.75 to about 0.5, and the acidified biologicals are stored at cold temperatures for a perod of time sufficient to inactivate microb...	10/19/1976

PatentStorm

Did You Know...

PatentStorm News

Class 536/7.5 - Purification or recovery