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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 4311830 | Apo--emulsans Growth of Acinetobacter Sp. ATCC 31012 on various substrates and under varying conditions has been used to produce two classes of extracellular microbial protein-associated lipopolysaccharides (the "emulsans") which, on a weight-for-weight basis, are prob... | 01/19/1982 |
| 4311829 | Apo-ଲ-emulsans Growth of Acinetobacter Sp. ATCC 31012 on various substrates and under varying conditions has been used to produce two classes of extracellular microbial protein-associated lipopolysaccharides (the "emulsans") which, on a weight-for-weight basis, are prob... | 01/19/1982 |
| 4280995 | Oral suspension of phenytoin The invention comprises a 5,5-diphenyl-2,4-imidazolidinedione-guaran complex formed by reacting an aqueous solution of guaran with an organic solvent solution of 5,5-diphenyl-2,4-imidazolidinedione. The invention also includes a therapeutic composition an... | 07/28/1981 |
| 4273765 | Amino sugar derivatives containing trehalose This invention relates to Trestatin A, Trestatin B and Trestatin C salts thereof and mixtures thereof as well as compositions containing at least one of the Trestatins A, B or C or a salt thereof. These compositions are useful for the inhibition of sucras... | 06/16/1981 |
| 4268505 | Pharmaceutical composition comprising a nitrogen-containing polysaccharide and an antibiotic agent, and a method of treating an infectious disease therewith A nitrogen-containing polysaccharide, which is obtainable by extracting mycelia of a fungus belonging to the genus Coriolus of Polyporaceae of Basidiomycetes with an aqueous solvent, is effectively used in treating a bacterial infectious disease due to th... | 05/19/1981 |
| 4259448 | Protein adsorbent and process for the purification of urokinase A novel protein adsorbent having a group of the general formula ##STR1## wherein X is hydrogen, halogen, amino, lower alkyl or lower alkoxycarbonyl as a ligand, is useful for the purification of urokinase by hydrophobic chromatography, particularly f... | 03/31/1981 |
| 4254257 | Amine salts of acidic microbial polysaccharides and their use in recovery of such polysaccharides Acidic polysaccharides of the type obtainable by microbial fermentation of an organic material such as a carbohydrate (e.g., xanthan gum) form novel amine salts with aliphatic or alicyclic polyamines having at least three amino nitrogen atoms and a molecu... | 03/03/1981 |
| 4243662 | Plant-virus controlling agent A novel product comprising nitrogen-containing polysaccharides is produced by bringing a culture product of fungi Basidomycetes into reaction with an aqueous ammoniacal solution at a temperature of 100° to 250° C. The product is remarkably effective in ... | 01/06/1981 |
| 4242501 | Purification of pneumococcal capsular polysaccharides A multivalent pneumococcal vaccine of the group consisting of immunogenic amounts of purified pneumococcal capsular polysaccharide (substantially absent "C" polysaccharide) of pneumococcal types (Danish designation) 1, 2, 3, 4, 6A, 6B, 7F, 8, 9N, 12F, 14,... | 12/30/1980 |
| 4235994 | High molecular weight meningococcal group C vaccine and method for preparation thereof A vaccine against Group C meningococcal meningitis consisting of a polysaccharide of which at least 80% by weight has a molecular weight in excess of 1,000,000 daltons is prepared. The polysaccharide was isolated from Group C hexadecyl trimethylammonium b... | 11/25/1980 |
| 4229570 | Method of producing nitrogen-containing polysaccharides The fungi belonging to the Coriolus genus is first extracted with water or a dilute alkaline solution and then further extracted stepwise by using alkaline solutions with gradually increased concentrations to obtain a nitrogen-containing polysaccharide ha... | 10/21/1980 |
| 4228275 | Nitrogen containing polysaccharide and process for preparing same A novel product comprising nitrogen-containing polysaccharides is produced by bringing a culture product of fungi Basidiomycetes into reaction with an aqueous ammoniacal solution at a temperature of 100° to 250° C. The product is remarkably effective in... | 10/14/1980 |
| 4202885 | Process for the preparation of anti-transplanted sarcoma 180 tumorigenic substances Extraction of a fungus of the class Basidiomycetes belonging to the Coriolus genus with an aqueous solvent under pressure and at a temperature of 120° C. to 200° C. gives an anti-transplanted sarcoma 180 tumorigenic substance in a high yield.... | 05/13/1980 |
| 4202969 | Method of producing nitrogen-containing polysaccharides The fungi belonging to the Coriolus genus are extracted by using a dilute alkaline solution having a concentration within a certain specified range whereby the low molecular weight substances with molecular weight of less than 5,000 are obtained in there ... | 05/13/1980 |
| 4183847 | Enzymatically hydrolyzable, serum-soluble cholesterol compounds and method for their preparation Water and serum soluble cholesterol compounds are prepared by reactively combining certain esters of cholesterol with a solubilizing agent selected from the group consisting of peptides, proteins, water soluble polycarboxylic acids, organic and inorganic ... | 01/15/1980 |
| 4169923 | High polymers containing nicotinic acid, process for their preparation and their use Polymers having molecular weight between 1,000 and 1,500,000 characterized in that they contain radicals of nicotinic acid bound to the macromolecular structure by covalent bonds that are gradually hydrolyzed in biological environment by setting free nico... | 10/02/1979 |
| 4167623 | Pullulan aminoalkyl ether Pullulan aminoalkyl ether is obtained by reacting pullulan with an aminoalkylating agent in a solvent in the presence of an alkali. This ether may be used as a cationic polymer of considerable utility in industries. For instance, when used in a paper coat... | 09/11/1979 |
| 4141973 | Ultrapure hyaluronic acid and the use thereof An ultra-pure, high molecular weight hyaluronic acid fraction which is characterized by the absence of significant cellular infiltration of the vitreous and anterior chamber, absence of significant flare in the aqueous humor, absence of significant haze o... | 02/27/1979 |
| 4140578 | Method of producing polysaccharides A fungus belonging to genus Coriolus of the class Basidiomycetes is subjected to submerged culture in a liquid medium and the obtained culture is dried and extracted with an aqueous solvent, and then the substances with molecular weights of less than 5,00... | 02/20/1979 |
| 4125492 | Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers Columns of polysaccharide, e.g., agarose, derivatives comprising covalently bonded gangliosides quantitatively adsorb the 125 I-labeled cholera toxin of chromatographed samples. The most preferred derivatives are those wherein the gangliosides ... | 11/14/1978 |
| 4075405 | ଲ-1,3-Glucan derivatives ଲ-1,3-Glucan derivatives, which are produced by reacting a water-insoluble ଲ-1,3-glucan with a cyanogen halide, are a useful water-insoluble carrier of high reactivity for the production of water-insoluble enzymes and of carrier-ligand product... | 02/21/1978 |
| 4057685 | Chemically modified endotoxin immunizing agent A bacterial endotoxin lipopolysaccharide of reduced toxicity covalently coupled to a protein antigen exhibits enhanced adjuvant effects. The coupling was affected by reaction with haloacylhalide. Lipopolysaccharide acylated with an anhydride of a dibasic ... | 11/08/1977 |
| 4053459 | Antibody specific to methaqualone and its metabolites A sensitive radioimmunoassay for methaqualone and its major metabolites is described. Included within this disclosure is the preparation of novel methaqualone haptens, the preparation of antigens from such haptens by coupling to an immunogenic carrier mat... | 10/11/1977 |
| 4024073 | Hydrogel and production thereof A novel and stable hydrogel contains a water-soluble polymer containing a chelating agent bound to the polymer chain, and a polyvalent metal ion cross-linking the polymer molecules through the chelating agent. The hydrogel is a carrier for timed release o... | 05/17/1977 |
| 3956272 | Polysaccharide gels A process for the treatment of polysaccharide gels, especially of agarose or gelose, comprises bridging the linear polysaccharide chains with 2,4,6-trichloro-1,3,5-triazine, e.g. by suspending the polysaccharide gel in a solution of 2,4,6-trichloro-1,3,5-... | 05/11/1976 |
| 3947352 | Polysaccharide matrices for use as adsorbents in affinity chromatography techniques Polysaccharide matrices, e.g., agarose, for use in certain affinity chromatography procedures, are activated with sodium metaperiodate, derivatized with a symmetrical dihydrazide and thence reductively stabilized, preferably with sodium cyanoborohydride. ... | 03/30/1976 |
| 3935072 | Purification of coenzyme A Coenzyme A is purified by a process involving contacting a cyanogen halide-activated water-insoluble polysaccharide with a cell-free extract of a coenzyme A-producing microorganism to immobilize proteins such as enzymes having affinity for coenzyme A on t... | 01/27/1976 |
