Bizarre Patents
Mouse device with a built-in printer
A mouse device for use as an input device of a computer is provided that includes a housing in which recording paper is loadable, and a printer unit provided within the housing for printing on the recording paper print information received from the computer.
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| Number | Title | Issue Date |
| 7799908 | Synthesis and use of 2′-substituted-N-modified nucleosides An improved method of preparing a sugar modified nucleoside analog includes a protocol in which a hydroxy group of a sugar is selectively deprotected and oxidized prior to nucleophilic modification of the corresponding carbonyl group. The modified sugar is then coup... | 09/21/2010 |
| 7777025 | Transition state analog inhibitors of ricin A-chain Improved transition state analog inhibitors of ricin toxin-A are provided. Methods of using those inhibitors to inhibit ricin toxin-A and to prevent the toxic effects of ricin toxin-A in a mammal are also provided. ... | 08/17/2010 |
| 7427679 | Precursors for two-step polynucleotide synthesis Precursors for use in the synthesis of polynucleotides are disclosed. The precursors include a heterocyclic base having an exocyclic amine group and a substituted or unsubstituted triaryl methyl protecting group bound to the exocyclic amine group. In particular embo... | 09/23/2008 |
| 7423144 | Purine Derivatives as adenosine Areceptor agonists and methods of use thereof The invention relates to Purine Derivatives; compositions comprising an effective amount of a Purine Derivative; and methods for reducing an animal's rate of metabolism, protecting an animal's heart against myocardial damage during cardioplegia; or for treating or p... | 09/09/2008 |
| 7385050 | Cleavable linker for polynucleotide synthesis Functionalized supports for polynucleotide synthesis are disclosed. The supports have linker moieties that are stable to conditions used in polynucleotide synthesis, but may be cleaved to release synthesized polynucleotides from the support. Methods of making the fu... | 06/10/2008 |
| 7375094 | Methods for decreasing or preventing pain using spicamycin derivatives Methods of providing pain relief by administering a water-soluble derivative of spicamycin. Methods of using pain mediation agents are also provided. ... | 05/20/2008 |
| 7342003 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs Provided is a method for the synthesis of an aralkyloxyadenosine or an alkoxyadenosine. The method includes protecting the hydroxyl sugar groups with a protecting group to produce a protected halogenated adenosine. The protected halogenated adenosine is alkoxylated,... | 03/11/2008 |
| 7335765 | Nucleoside and oligonucleotide analogues A compound of the formula (1): wherein R1 and R2 are the same or different and represent a hydrogen atom, a hydroxyl protecting group, a phosphate group, or —P(R3)R4, wherein R | 02/26/2008 |
| 7321828 | System of components for preparing oligonucleotides Interative, preferably computer based iterative processes for generating synthetic compounds with desired physical, chemical and/or bioactive properties, i.e., active compounds, are provided. During iterations of the processes, a target nucleic acid sequence is prov... | 01/22/2008 |
| 7314923 | Nucleoside and oligonucleotide analogues A probe for a gene or a primer for starting amplification comprising an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of the nucleoside units is a structure of the formula (2): ... | 01/01/2008 |
| 7300923 | Partial and full agonists of A1 adenosine receptors Disclosed are syntheses suitable for large scale manufacture of novel compounds that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular tachycardia and atrial flutter, angina, and myocardial infa... | 11/27/2007 |
| 7271157 | Aadenosine receptor agonists Disclosed is a synthesis suitable for large scale manufacture of novel compounds that are partial and full A1 adenosine receptor agonist having the structure of Formula I: wherein R is optionally subst... | 09/18/2007 |
| 7271258 | Methods of synthesizing oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection The invention provides methods for synthesizing oligonucleotides using nucleoside monomers having carbonate protected hydroxyl groups that are deprotected with α-effect nucleophiles. The α-effect nucleophile irreversibly cleave the carbonate protecting groups whil... | 09/18/2007 |
| 7262176 | Adenosine A receptor agonists Disclosed are novel compounds that are A3 adenosine receptor agonists, useful for treating various disease states, including cancer, cardiac ischemia, leukopenia, and neutropennia. ... | 08/28/2007 |
| 7238676 | Purine derivatives The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and composition... | 07/03/2007 |
| 7217815 | 2-beta -modified-6-substituted adenosine analogs and their use as antiviral agents Various 2′-beta-methyl-6-substituted adenosine analogs (including 2,6-disubstituted adenosine, 8-aza-6-substituted adenosine, and 2-aza-6-substituted adenosine) are prepared by conventional and combinatorial library approaches. Contemplated compounds are particula... | 05/15/2007 |
| 7214665 | 2-propynyl adenosine analogs having Aagonist activity and compositions thereof The invention provides compounds having the following general formula (I): wherein X, R1, R2, R7 and Z are as described here. ... | 05/08/2007 |
| 7199127 | Purine nucleosides Disclosed are purine nucleoside compounds that are selective to A3 adenosine receptors and are useful for the treatment of cancer and inflammatory diseases. The compounds are shown by the following general formula (I), including isomers thereof: | 04/03/2007 |
| 7196071 | Methods of decreasing or preventing pain using spicamycin derivatives Methods of providing pain relief by administering a water-soluble derivative of spicamycin. Methods of using pain mediation agents are also provided. ... | 03/27/2007 |
| 7182939 | Hair tonic composition A hair tonic composition containing adenosine, adenosine 5′-phosphate, and/or an adenosine 5′-phosphate salt as an active ingredient. ... | 02/27/2007 |
| 7163928 | Partial and full agonists of Aadenosine receptors Disclosed are novel compounds that are partial and full A1 adenosine receptor agonists, useful for treating various disease states, in particular tachycardia and atrial flutter, angina, and myocardial infarction. ... | 01/16/2007 |
| 7148223 | 4′-thio-L-xylo furanosyl nucleosides, precursors thereof, preparation and use thereof Compounds represented by the formula 1: A is selected from the group consisting of wherein each R individually is H or... | 12/12/2006 |
| 7141553 | A3AR agonists for the treatment of inflammatory arthritis The present invention concerns a method for the treatment of inflammatory arthritis, and in particular rheumatoid arthritis, by administering to the subject specific low dosages of N6-(3-iodobenzyl)-adenosine 5′-N-methyl-uronamide (IB-MECA) and 2-chloro-N6-(3-iodo... | 11/28/2006 |
| 7109180 | C-pyrazole Areceptor agonists 2-adenosine C-pyrazole compounds having formula (a) and methods for using the compounds as A2A receptor agonists to stimulate mammalian coronary vasodilatation for therapeutic purposes and for purposes of imaging the heart ... | 09/19/2006 |
| 7002006 | Protection of nucleosides A process of manufacturing protected nucleosides comprises reacting a nucleoside with a protecting reagent in the presence of a regioselective activator to produce a regioselectively protected nucleoside. In some embodiments of the inventive method, an optionally su... | 02/21/2006 |
| 6995148 | Adenosine cyclic ketals: novel adenosine analogues for pharmacotherapy The present invention relates to novel compounds that are novel adenosine receptor analogues. Specifically, the compounds of the present invention preferably function as both adenosine receptor agonists and ganglionic blocking agents. To achieve this functionality, ... | 02/07/2006 |
| 6972330 | Chemical synthesis of methoxy nucleosides Process for chemical synthesis of methoxy nucleosides. ... | 12/06/2005 |
| 6958214 | Polymorphic kinase anchor proteins and nucleic acids encoding the same Polymorphic A-kinase anchor proteins (AKAPs) and nucleic acids encoding the proteins are provided herein. Methods of detecting polymorphic AKAPs and nucleic acids encoding the AKAPs, and kits for use in the detection methods are also provided. Further provided herei... | 10/25/2005 |
| 6951932 | Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines The invention provides new methods for synthesis of 2-aralkyloxyadenosines and 2-alkoxyadenosines. The invention is particularly useful for synthesis of 2-[2-(4-chlorophenyl)ethoxy]adenosine. Preferred methods of the invention include activating a guanosine compound... | 10/04/2005 |
| 6949640 | Method for synthesizing 2-chloro-9-(2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-9-amine is synthesized by reacting a 2-chloro-6-substituted purine with a protected and activated 2-deoxy-2-fluoro-D-arabinofuranose; and reacting with a base such as ammonia to provide 2-chloro-9-(2-deoxy... | 09/27/2005 |
| 6924271 | 3-β-D-ribofuranosylthiazolo[4-5-d]pyridimine nucleosides and uses thereof The invention is directed to 3-β-D-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compou... | 08/02/2005 |
| 6921753 | Purine derivatives The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions cont... | 07/26/2005 |
| 6914148 | Guanidinium functionalized intermediates The present invention provides oligomers which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligomer is modified to include a guanidinium group. These oligomers are useful for diagnostic,... | 07/05/2005 |
| 6914061 | 4′-thio-L-xylofuranosyl nucleosides, precursors thereof, preparation and use thereof Compounds represented by the formula 1: A is selected from the group consisting of wherein each R individually is H or acyl, Y is X, N3,... | 07/05/2005 |
| 6906190 | Inhibitors for de novo-RNA polymerases and methods of identifying targets for same A polymerase inhibitor has first moiety coupled to a second moiety via an optional linker in which the first moiety binds to an initiation nucleotide binding site of a polymerase and forms at least two hydrogen bonds with an RNA template strand that is associated wi... | 06/14/2005 |
| 6903079 | Nucleoside compounds and compositions thereof The invention provides a novel class of substituted nucleoside derivatives having the formula: A-Z1-L-Z2-G wherein: A and G are connected via Z1 and Z2 respectively, to a linker, L; and A i... | 06/07/2005 |
| 6900309 | Purine derivatives The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, and to processes for the preparation of, intermediates used in the preparation of, compositions cont... | 05/31/2005 |
| 6884880 | Process for the preparation of 9-β-anomeric nucleoside analogs A process for substantially enhancing the regio and stereoselective synthesis of 9-β-anomeric nucleoside analogs is described. The introduction of the sugar moiety onto a 6-substituted purine base was preformed so that only the 9-β-D- or L-purine nucleoside analog... | 04/26/2005 |
| 6855818 | C-pyrazole A2A receptor agonists 2-adenosine C-pyrazole compositions having the following formula: and methods for using the compositions as A2A receptor agonists to stimulate mammalian coronary vasodilatation for therapeutic purposes and f... | 02/15/2005 |
| 6831072 | Compositions and methods of synthesis and use of novel nucleic acid structures The present invention is directed to a method to produce 8-amino-2′deoxyadenosine by treating 8-azido-2′deoxyadenosine with an aqueous solution of methylamine or dimethylamine. ... | 12/14/2004 |
