Bizarre Patents
A forehead support apparatus for resting a standing users forehead against a wall above a bathroom commode or urinal or beneath a showerhead.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7476734 | Nucleotide analogs The invention provides nucleotide analogs for use in sequencing nucleic acid molecules. ... | 01/13/2009 |
| 7319093 | Antidiabetic 2-substituted-5′-O-(1-Boranotriphosphate) adenosine derivatives 2-Substituted-5′-O-(1-boranotriphosphate)adenosine derivatives having at position 2 a radical R1 selected from the group consisting of H; halogen; O-hydrocarbyl; S-hydrocarbyl; NR3R4; and hydrocarbyl optionally substituted by halogen, CN, SCN, NO2, OR3, SR3 or NR3... | 01/15/2008 |
| 7291606 | Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging Novel compositions and methods are provided for identifying agents which affect chromosomal stability and aging. ... | 11/06/2007 |
| 7279311 | Use of nucleic acids bound to carrier macromolecules A nucleic acid primer is bound to a soluble carrier macromolecule, a multitude of primer molecules thus being carried by each carrier macromolecule, and hybridisation of the primer to a template followed by extension of the primer to replicate the template in comple... | 10/09/2007 |
| 7223744 | Pharmaceutical formulation comprising dinucleoside polyphosphates and salts thereof The present invention provides a method of treating edematous retinal disorders. The method comprises administration of a pharmaceutical formulation comprising a hydrolysis-resistant P2Y receptor agonist to stimulate the removal of pathological extraneous fluid from... | 05/29/2007 |
| 7078391 | Method of treating edematous retinal disorders The present invention provides a method of treating edematous retinal disorders. The method comprises administration of a pharmaceutical formulation comprising a hydrolysis-resistant P2Y receptor agonist to stimulate the removal of pathological extraneous fluid from... | 07/18/2006 |
| 7056894 | Inhibitors of ADP-ribosyl transferases, cyclases, and hydrolases, and uses thereof The present invention provides compounds having the formula: wherein A is chosen from a nitrogen-, oxygen-, or sulfur-linked aryl, alkyl, cyclic, or heterocyclic group; both B and C are hydrogen, or either B or C... | 06/06/2006 |
| 7026469 | Compositions and methods of double-targeting virus infections and cancer cells The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions o... | 04/11/2006 |
| 7022680 | Inhibitors of ADP-ribosyl transferases, cyclases, and hydrolases The present invention provides compounds having the formula: wherein A is a nitrogen-, oxygen-, or sulfur-linked aryl, alkyl, cyclic, or heterocyclic group, the group being further substituted with an electron contribut... | 04/04/2006 |
| 6987180 | Uridine analogs and techniques for making and using Uridine analogs and techniques for making and using uridine analogs are disclosed in this invention. These uridine analogs include nucleoside phosphates having a 5-aminouracil group. These nucleotides can be incorporated into a nucleic acid as an unnatural base, as ... | 01/17/2006 |
| 6812342 | Esters of cyclic ADP ribose derivatives The present invention is directed to the field of organic chemistry in general and specifically to the preparation of hydrophobic derivatives of cyclic ADP ribose. One form of the present invention is the composition of one or more hydrophobic derivatives of cyclic ... | 11/02/2004 |
| 6780988 | Processes for producing P1,P4-diuridine-5′-tetraphosphate The invention describes a process for producing P1,P4-di(uridine-5′-)tetraphosphate (U2P4) or a salt thereof from uridine 5′-monophosphate (UMP); wherein the process comprises at least one of the steps (a) and (b): (a)... | 08/24/2004 |
| 6673779 | Method of treating ciliary dyskinesia with dinucleoside polyphosphate compounds or UTP analogues The present invention is directed to a method of stimulating ciliary beat frequency to promote mucociliary or cough clearance of retained mucus secretions from the lungs, sinuses, upper airways, ears, eyes, genito-urinary tract, spermatozoa, ovaries, fall... | 01/06/2004 |
| 6670341 | Compositions and methods for double-targeting virus infections and targeting cancer cells The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The com... | 12/30/2003 |
| 6458946 | Crystals of diuridine tetraphosphate or salt thereof, process for producing the crystals, and process for producing the compounds The invention provides crystals of p1,P4 -di(uridine 5'-) tetraphosphate or a salt thereof; a process for producing the crystals; and a process for producing P1,P4 -di(uridine 5'-) tetraphosphate (U2 ... | 10/01/2002 |
| 6448392 | Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use Compounds are disclosed for treating AIDS, herpes, and other viral infections by means of lipid derivatives of antiviral agents. The compounds consist of nucleoside analogues having antiviral activity which are linked, commonly through a phosphate group a... | 09/10/2002 |
| 6268183 | Method of purifying thuringiensin The invention discloses a two-step process for recovery of thuringiensin, comprising adsorbing the thuringiensin from fermentation broth by calcium silicate, and dissociating the thuringiensin by dibasic sodium phosphate. The resulting thuringiensin can b... | 07/31/2001 |
| 6255292 | Purine nucleotide analogues, pharmaceutical compositions thereof, and methods of improving cardiac functions The specification discloses purine nucleotide analogues which modulate cardiac muscle contractility and possess vasodilator activity. In addition, related methods of administration and the identity of receptors that bind these compounds are disclosed.... | 07/03/2001 |
| 6132957 | Method and compounds for the inhibition of adenylyl cyclase The present invention reveals a new series of derivatives and analogues of adenine and adenosine, i.e., 3'-adenosine derivatives, which inhibit adenylyl cyclase activity. These newly synthesized compounds include the most potent inhibitors of adenylyl cyc... | 10/17/2000 |
| 5948648 | Nucleotide compounds including a rigid linker A nucleoside/tide compound having the structure NUC--L--S--LB/LG is described wherein NUC is a nucleoside/tide having a nucleobase portion B, L is a rigid linkage, S is a spacer; and LB/LG is a member of a linkage pair or a label. NUC is attached to L through ... | 09/07/1999 |
| 5872243 | Caged nucleotides The present invention describes a family of photolabile caged nucleotides, including cyclic nucleotides. The compounds of the present invention are caged analogs and derivatives of NAD+, NADH, NADP, NADPH, NAADP and cADPR. The photolysis of the... | 02/16/1999 |
| 5795756 | Method and compounds for the inhibition of adenylyl cyclase The present invention reveals a new series of derivatives and analogues of adenine and adenosine, i.e., 3'-adenosine derivatives, which inhibit adenylyl cyclase activity. These newly synthesized compounds include the most potent inhibitors of adenylyl cyc... | 08/18/1998 |
| 5582980 | Chemiluminescent 1,2-dioxetanes Spiroadamantyl dioxetanes bearing an alkoxy substituent, and a phenyl substituted on the dioxetane ring can be activated to chemiluminesce if the aromatic substituent bears a meta-substituted moiety designated OX, wherein the X is cleaved by an enzyme wit... | 12/10/1996 |
| 5512671 | Ether lipid-nucleoside covalent conjugates Ether lipid nucleoli covalent conjugates and derivatives thereof are disclosed, along with pharmaceutical compositions containing the same and methods of using the same to combat HIV-1 infections. Illustrative are 3'-Azido-3'-deoxythmidine-5'-monophosphat... | 04/30/1996 |
| 5486604 | Cyclic ADP ribose antagonists Cyclic ADP-ribose (cADPR) analogs block cADPR from releasing Ca+2, and also inhibit cADPR from potentiating Ca+2 release induced by either divalent cations or by caffeine. 8-amino-cADPR and two other 8-substituted analogs were also ... | 01/23/1996 |
| 5436231 | Adenophostins Compounds of formula (I): ##STR1## (wherein R represents a hydrogen atom or an acetyl group), which we have named "the adenophostins", and, have the ability to increase intracellular calcium ion concentrations by acting on the inositol 1,4,5-trisphos... | 07/25/1995 |
| 5380715 | Ap4 A as a hypotensive agent A deliberated hypotensive agent is composed of diadenosine 5', 5'"-p1,p4 -tetraphosphate with formula (I) or a salt thereof for which administration is medically permissible in an effective amount: ##STR1##... | 01/10/1995 |
| 5348941 | Stabilizers for fibroblast growth factors Medicinal compositions containing fibroblast growth factor are stabilized against loss of biological activity by including in said composition a stabilizing amount of phytic add, phosvitin, phosphate buffer, (NH4)6 P4 O | 09/20/1994 |
| 5268464 | Process for the preparation of nucleosides A process for the preparation of natural or synthetic nucleosides, nucleoside analogs or oligonucleotides from at least two such nucleosides and/or nucleoside analogs whose basic molecule contains an unsubstituted or substituted radical of a nucleic base ... | 12/07/1993 |
| 5220005 | Substituted adamantyl dioxetanes Dioxetane compounds reactable with an enzyme to release optically detectable eneregy are disclosed. These compounds have the formula: ##STR1## wherein T is a carboxylic acid or methoxy substituted adamantyl group bound to the ring through a spiro bon... | 06/15/1993 |
| 5198539 | 5'-esters of 2',3'-dideoxy-3'-fluoro-5-ethynyluridine The present invention relates to a 3'-substituted pyrimidine nucleoside and its use in medical therapy, particularly in the treatment of HIV infections. Also provided are pharmaceutical formulations.... | 03/30/1993 |
| 5192749 | 4'-substituted nucleosides Nucleosides compounds of Formula I: ##STR1## wherein B is a purine or a pyrimidine; X and X' are H; Y is H; Y' is OH, F or H; or Y' and X' together makes a bond; Z is ##STR2## where n is zero, one, two or three; or Y' and Z together form a cyclic ... | 03/09/1993 |
| 5190926 | 3'-azido-2',3'-dideoxypyrimidines and related compounds as antiviral agents A pharmaceutical composition in dosage unit form comprising a therapeutically effective HIV inhibitory amount of a compound having the formula: ##STR1## wherein R1 is selected from the group consisting of OH, C1-4 acyl, sul... | 03/02/1993 |
| 5109125 | Process for purifying nucleoside-5'-diphosphates This invention is a process for purifying nucleoside-5'-diphosphates containing substituents other than primary amines (hereinafter designated as NDPs) from complex mixtures by contacting the aqueous solution mixture with a strongly basic ion exchange res... | 04/28/1992 |
| 5087565 | Synthetic process for preparation of 32 P-labeled nucleotides A process for the production of 32 P-labeled nucleotides in accordance with an enzymatic pathway utilizing phosphotransacetylase and acetate kinase.... | 02/11/1992 |
| 4990498 | 2- and 8-azido(2'-5')oligoadenylates and antiviral uses thereof Compounds of the formula ##STR1## REFERENCE TO GOVERNMENT GRANT The invention described herein was made, in part, in the course of work supported by National Institutes of Health Grants GM 27210 and CA 29545, and National Science Foundation Grant PCM 84-1... | 02/05/1991 |
| 4983727 | Palladium mediated reaction of organic disulfides with mercurated nucleic acid components A method of preparing C-5 substituted nucleotides by reacting a C-5 posit mercurated nucleoside with an alkyl or aryl disulfide in the presence of palladium(II) ion. The resulting new method for attaching linker arms to nucleic acids (DNA,RNA) provides a... | 01/08/1991 |
| 4981957 | Oligonucleotides with modified phosphate and modified carbohydrate moieties at the respective chain termini The invention relates to novel oligonucleotides, the process for their preparation and their biological uses as mediators of the action of interferon. The oligonucleotides according to the invention have the formula: ##STR1## in which Y and T ar... | 01/01/1991 |
| 4965350 | Pyridopyrimidine nucleotide compounds Pyridopyrimidine nucleotide derivatives expressed by formula (I), which are fluorescent and capable of forming base pairing with guanine or adenine, and oligo- or polynucleotide which have at least one of these derivatives in their molecules or at their m... | 10/23/1990 |
| 4952685 | Detectable molecules, method of preparation and use A detectable molecule of the formula A3 --(--X--R1 --E--Detb)m where A3 is A2 or a polymer, where A3 has at least one modifiable reactive group selected from the group consisting of amino,... | 08/28/1990 |
