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...that it was melting ice cream that inspired the invention of the outboard motor? It was a lovely August day and Ole Evinrude was rowing his boat to his favorite island picnic spot. As he rowed, he watched his ice cream melt and wished he had a faster way to get to the island. At that moment the idea for the outboard motor was born!

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Class 536/23.2 - Encodes an enzyme


Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which are DNA fragments which encode specific
No. of patents: 6495
Last issue date: 05/29/2012


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NumberTitleIssue Date
7351562Ribulose 1,5-bisphosphate carboxylase/oxygenase polypeptides and related polynucleotides
The present invention relates to novel ribulose-1,5-bisphosphate carboxylase/oxygenase polypeptides and the polynucleotides that encode them. The invention also provides related host cells and methods. ...
04/01/2008
7351542Methods of modulating tubulin deacetylase activity
The present invention provides methods for identifying agents that modulate a level or an activity of tubulin deacetylase polypeptide, as well as agents identified by the methods. The invention further provides methods of modulating tubulin deacetylase activity in a...
04/01/2008
7351565Plant caffeic acid 3-O-methyltransferase homologs
This invention relates to an isolated nucleic acid fragment encoding a protein involved in phenylpropanoid metabolism. The invention also relates to the construction of a chimeric gene encoding all or a portion of the protein involved in phenylpropanoid metabolism, ...
04/01/2008
7351563Cell-free extracts and synthesis of active hydrogenase
Enzymatically active hydrogenase is synthesized in a cell-free reaction. The hydrogenases are synthesized in a cell-free reaction comprising a cell extract derived from microbial strains expressing at least one hydrogenase accessory protein. In some embodiments, the...
04/01/2008
7351564SQS gene
The present invention relates to a gene useful in a process to increase the microbial production of carotenoids. The carotenoids astaxanthin is distributed in a wide variety of organisms such as animals, algae and microorganisms. It has a strong antioxidation proper...
04/01/2008
735156627877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552, and 65577 molecules and uses therefor
The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors co...
04/01/2008
7351811Gene SCC-112 and diagnostic and therapeutic uses thereof
A gene that is a modulator of tumor growth and metastasis in certain cancer types is provided. SCC-112 (about 150 kDa) and/or a mutant form of SCC-112 (about 65 kDa) is a tumor suppressor molecule. This gene and corresponding polypeptide have diagnostic and therapeu...
04/01/2008
7351813Liver-specific gene expression cassettes, and methods of use
In one aspect, the present invention provides nucleic acid expression cassettes that are predominantly expressed in the mammalian liver. The present invention also provides vectors comprising a nucleic acid expression cassette that is predominantly expressed in the ...
04/01/2008
7351571Process for the production of β-amino acids using acylase
The present invention relates to a Variovorax sp. which produces an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and a Burkholderia sp. which produces both an acylase having an...
04/01/2008
7351568EGVI endoglucanase and nucleic acids encoding the same
The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant E...
04/01/2008
7351569Aldolase and production process of substituted α-keto acids
4-(Indol-3-ylmethyl)-4-hydroxy-2-oxoglutarate, which is useful as an intermediate in the synthesis of monatin, may be synthesized from indole pyruvic acid and pyruvic acid (and/or oxaloacetic acid) by using a novel aldolase derived from the genus Pseudomonas, Erw...
04/01/2008
7348469Plant farnesyltransferases
This invention relates to an isolated nucleic acid fragment encoding a farnesyltransferase subunit. The invention also relates to the construction of a chimeric gene encoding all or a portion of the farnesyltransferase subunit, in sense or antisense orientation, whe...
03/25/2008
7348170Fungus-origin lysyl oxidases
Lysyl oxidase derived from filamentous fungi and a DNA encoding thereof are provided. Lysyl oxidase including a protein described in of the following (a) or (b): (a) a protein having an amino acid sequence set forth in SEQ ID NO: 2; or (b) a protein having an amino ...
03/25/2008
7348171N-acetylglucosaminyltransferase Vb coding sequences, recombinant cells and methods
A previously unknown mammalian UDP-N-acetylglucosamine:α-6-D-mannoside β-1,6-N-acetylglucosaminyl-transferase (termed GlcNAc T-Vb herein) coding sequence, protein, recombinant host cells and antibodies which specifically bind GlcNAc T-Vb are described. GlcNAc T-Vb...
03/25/2008
7348172Method and DNA constructs for increasing the production level of carbohydrate degrading enzymes in filamentous fungi
The invention is related to a method and DNA constructs for obtaining in a filamentous fungus host a higher production level of a carbohydrate degrading (CD) enzyme, having in its original state a catalytic module (CAT) and a carbohydrate binding module (CBM) separa...
03/25/2008
7348168Polypeptides having cellobiohydrolase II activity and polynucleotides encoding same
The present invention relates to polypeptides having cellobiohydrolase II activity and polynucleotides having a nucleotide sequence, which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nuc...
03/25/2008
7348173Fatty-acid amide hydrolase
The soporific activity of cis-9,10-octadecenoamide and other soporific fatty acid primary amides is neutralized by hydrolysis in the presence of fatty-acid amide hydrolase (FAAH). Hydrolysis of cis-9,10-octadecenoamide by FAAH leads to the formation of oleic acid, a...
03/25/2008
7348421Methods for production of -hydroxybenzoate in bacteria
This invention relates to the isolation of a novel tonB operon from Pseudomonas putida. These genes are useful to render the cells more sensitive to antibiotics, toluene, pHBA, aromatic compounds, parabenes, and aromatic amino acids after inactivation with sp...
03/25/2008
7344855Fermentation process
A process for the preparation of a target fermentation product comprising cultivation of an aerobic microorganism to produce such product, wherein in the microorganism the efficiency of the respiratory chain is increased, transformed and novel nucleotide sequences.
03/18/2008
7344869Isolated DNA comprising one or more genes specific for 5S clavam biosynthesis, vectors comprising such DNA and hosts capable of improved clavulanic acid production
Novel bacterial genes, microorganisms and processes for improving the manufacture of 5R clavams, eg. clavulanic acid. ...
03/18/2008
7344871BGL5 β-glucosidase and nucleic acids encoding the same
The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl5, and the corresponding BGL5 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL5, recombinant ...
03/18/2008
73448703-phosphoinositide-dependent protein kinase
The present invention provides for a substantially pure human or rabbit 3-phosphoinositide-dependent protein kinase. ...
03/18/2008
7344886Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product
The invention relates to modified neomycin phosphotransferase genes and their use in a selection method for high-producing recombinant cells. The invention further relates to expression vectors which contain a modified neomycin phosphotransferase gene and a gene of ...
03/18/2008
7344844Compositions and methods of using apoptosis signaling kinase related kinase (ASKRK)
The invention provides apoptosis signaling kinase related kinase (ASKRK) nucleic acid and polypeptide sequences and methods of using such sequences to identify modulators of ASKRK. Such modulators can be used for the treatment of diabetes or for delaying the onset o...
03/18/2008
7341861Non-ribosomal peptide synthetases and associated biosynthetic genes
The present invention describes the identification of novel non-ribosomal peptide synthetases and associated biosynthetic genes from Streptomyces hygroscopicus. The present invention further provides methods for generating novel compounds, such as antibiotics...
03/11/2008
7341856Production of polyhydroxyalkanoate in plants
The invention relates to the genetic manipulation of plants to produce polyhydroxyalkanoate, particularly in the peroxisomes. Methods for producing such polymers in plants and host cells are provided. Such methods find use in producing biodegradable thermoplastics i...
03/11/2008
7341853Method for glycosylating hydroxylysine residues
This invention relates to a multifunctional enzyme having lysyl hydroxylase and glycosyltransferase activity and to the use of the enzyme in glycosylating hydroxylysine residues. In particular this invention relates to a method for producing glycosyltransferase acti...
03/11/2008
7342108De novo DNA cytosine methyltransferase genes, polypeptides and uses thereof
De novo DNA cytosine methyltransferase polynucleotides and polypeptides and methods for producing said polypeptides are disclosed. Also disclosed are methods for utilizing de novo DNA cytosine methyltransferase polynucleotides and polypeptides in diagnostic assays, ...
03/11/2008
7341859ADH from
The present invention relates to an alcohol dehydrogenase from Rhodococcus erythropolis. By means of such cofactor-dependent ADHs, chiral alcohols, which can be of use for use in organic syntheses, can advantageously be obtained with a cofactor-regenerating e...
03/11/2008
7342101Compositions and methods comprising a protective antigen of
Disclosed are protein and peptide antigen and DNA compositions effective in generating immune responses against the pathogenic fungi Coccidioides spp., the causative agents of coccidioidomycosis and Valley Fever. The invention thus provides protein and peptid...
03/11/2008
7339092Plant activation of Cry8Bb1 by insertion of a plant protease-sensitive site
Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut pro...
03/04/2008
7338790Alleles of the gnd gene from coryneform bacteria
The invention relates to mutants and alleles of the gnd gene from coryneform bacteria coding for 6-phosphogluconate dehydrogenases which contain at position 329 or a comparable position of the amino acid sequence any amino acid other than L-valine, and to processes ...
03/04/2008
7339038Heparanase specific molecular probes and their use in research and medical applications
A variety of heparanase specific molecular probes which can be used for research and medical applications including diagnosis and therapy. Specific applications include the use of a heparanase specific molecular probe for detection of the presence, absence or level ...
03/04/2008
7335475PR/SET-domain containing nucleic acids, polypeptides, antibodies and methods of use
The present invention provides an isolated nucleic acid molecule encoding a PFM/SET polypeptide. Also provided is an isolated nucleic acid molecule encoding a functional fragment of a PFM/SET polypeptide that contains a PR, SET, PRAZ or PKZL domain of a PFM/SET poly...
02/26/2008
7335815Nucleic acid sequences to proteins involved in isoprenoid synthesis
Methods are provided for producing plants and seeds having altered isoprenoid content and compositions. The methods find particular use in increasing the isoprenoid levels in plants, and in providing desirable isoprenoid compositions in a host plant cell. ...
02/26/2008
7335760Nucleic acid sequences encoding zinc finger proteins
Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants. ...
02/26/2008
7335484Retinoid metabolizing protein
Amino acid sequences and corresponding nucleic acid sequence of retinoid metabolizing protein found in human, mouse and zebrafish are described, as well as methods of using same. ...
02/26/2008
7335499tRNA synthetase
The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection again...
02/26/2008
7335757Carbonyl reductase, gene encoding the same, and process for producing optically active alcohols using the same
According to the present invention, there is provided a novel carbonyl reductase derived from a microbial belonging to the genus Ogataea and a DNA encoding the enzyme. By reducing ketones with the use of the carbonyl reductase, optically active alcohols, in p...
02/26/2008
7335503Expression of granular starch hydrolyzing enzyme in
The present invention relates to filamentous fungal host cells and particularly Trichoderma host cells useful for the production of heterologous granular starch hydrolyzing enzymes having glucoamylase activity. ...
02/26/2008
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