Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 4405612 | Heparin web compositions Microfibrous heparin salts, nonwoven webs of such fibers, a process for preparing the fibers and the use of the webs for the rapid heparinization of blood are disclosed.... | 09/20/1983 |
| 4401662 | Oligosaccharides having anti-Xa activity and pharmaceutical compositions containing them Oligosaccharides obtainable from heparin including heparinic constituents of molecular weights ranging from 2000 to 50,000. Said fractions have a Yin-Wessler titer and a USP titer in a ratio of at least 30. They consist of chains constituted by no more th... | 08/30/1983 |
| 4401758 | Process for making oligosaccharides having anti-Xa activity and the resulting oligosaccharides Oligosaccharides obtainable from heparin including heparinic constituents of molecular weights ranging from 2000 to 50,000. Said fractions have a Yin-Wessler titer and a USP titer in a ratio of at least 30. They consist of chains substituted by no more than 8 ... | 08/30/1983 |
| 4396762 | Heparinase derived anticoagulants There is disclosed a heparin product obtained by degradation of heparin with heparinase from Flavobacterium heparinum (ATCC 13125) or mutants thereof having activity to reduce the coagulation activity of factor X while not effecting the coagulation activi... | 08/02/1983 |
| 4386025 | Method of preparing antithrombin A lectin-containing, water-insoluble gel matrix with a glycoprotein reversibly bound thereto can be used for fractionating a polysaccharidic substance capable of being separated into components of differing activity by virtue of differing affinity for the... | 05/31/1983 |
| 4385046 | Diagnostic radio-labeled polysaccharide derivatives A novel class of chelated radio-labeled polysaccharide derivatives are useful for diagnosing formed, and forming, blood clots in a vascular system. Novel intermediate metal-binding compounds comprise a water-soluble polysaccharide moiety having an average... | 05/24/1983 |
| 4351938 | Anticoagulant substance Partially depolymerized heparin products having particular analyzable reducing end groups, a process for their preparation and their use as anticoagulants and antithrombotics.... | 09/28/1982 |
| 4346216 | Osmium carbohydrate complexes Osmium carbohydrate complexes prepared by reacting osmium compounds and carbohydrates and their utilization as pharmaceutical compositions for the treatment of heavy metal poisoning and arthritis in mammals. The osmium carbohydrate complexes may also be u... | 08/24/1982 |
| 4343736 | Process for recovering interferon A process for recovering interferon which comprises contacting a solution containing an interferon produced by the induced cells of human origin with a water-insolubilized sulfated polysaccharide to allow the interferon to be adsorbed on the water-insolub... | 08/10/1982 |
| 4331697 | Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative A heparin derivative in which at least 0.5% of the entire hydroxyl groups of heparin are in the form of an ester of the following formula ##STR1## wherein R1, R2 and R3 each represent a hydrogen atom or an alkyl group... | 05/25/1982 |
| 4329383 | Non-thrombogenic material comprising substrate which has been reacted with heparin Non-thrombogenic material comprising a base polymer treated with heparin, the improvement in which the heparin is covalently bonded with the base polymer through only one acetal bond or hemiacetal bond at each bonding site between the heparin and the base... | 05/11/1982 |
| 4315923 | Process for the production of organ extracts with high herparin content A process for producing an aqueous solution of high heparin content from heparin-containing animal organs comprises forming a heparin-enriched granular raw material from these organs and extracting the raw material at a temperature of 20° to 80° C. with... | 02/16/1982 |
| 4314935 | Process for recovering interferon A process for recovering interferon which comprises contacting a solution containing an interferon produced by the induced cells of human origin with a water-insolubilized sulfated polysaccharide to allow the interferon to be adsorbed on the water-insolub... | 02/09/1982 |
| 4303651 | Heparin fragments having selective anticoagulation activity Heparin fragments having selective anticoagulation activity having 14-18 sugar units, the disaccharide unit L-iduronosyl-2-O-sulphate-N-sulpho-U-glucosamine-6-O-sulphate being the main component, and where unsulphated L-iduronic acid is in a position ... | 12/01/1981 |
| 4301153 | Heparin preparation A heparin preparation which exhibits elevated anticoagulant activity and a process for producing the preparation. Conventional heparin exhibiting characteristic anticoagulant activity and molecular heterogeneity is incubated with antithrombin-heparin cofa... | 11/17/1981 |
| 4301067 | Chitin containing poly-ion complex This invention relates to a poly-ion complex comprising chitin or N-acylchitosan derivative having carboxymethyl and polyelectrolyte.... | 11/17/1981 |
| 4283530 | Process for the preparation of heparin Heparin is extracted from intestinal brine, i.e., from the brine which results from the preservation and dewatering treatment of animal tissue with sodium chloride, using conventional methods. The extracted product has a high activity and can subsequently... | 08/11/1981 |
| 4281108 | Process for obtaining low molecular weight heparins endowed with elevated pharmacological properties, and product so obtained The present invention relates to a process for obtaining low molecular weight heparins endowed with pharmacological and therapeutic properties of outstanding interest, starting from normal heparin. The said process is characterized in that it comprises the fol... | 07/28/1981 |
| 4260741 | Low-density xanthan gums A form of xanthan gum is disclosed which is less dense than regular xanthan gum and which exhibits an increased hydration rate.... | 04/07/1981 |
| 4250041 | Removal of heparin from blood plasma samples using an insoluble protamine reaction product This invention relates to a method for the removal of heparin from heparin-containing plasma test samples using an insoluble protamine reaction product, without adversely affecting subsequent testing of the plasma for clotting time. Protamine sulfate or a... | 02/10/1981 |
| 4239754 | Liposomes containing heparin and a process for obtaining them Heparin-based preparations wherein heparin is retained in or on liposomes. The lipids of said liposomes are preferably phospholipids comprising acyl chains derived from non saturated fatty acids, advantageously essential acids. These heparin-liposomes preparat... | 12/16/1980 |
| 4226599 | Removal of heparin from heparin-containing blood plasma samples using a triethylaminoethyl cellulose tablet A tableted form of fibrous triethylaminoethyl cellulose suitable for the removal of heparin from heparin-containing blood plasma. The tablet is composed of granular microcrystalline cellulose and fibrous triethylaminoethyl cellulose in a ratio of from abo... | 10/07/1980 |
| 4192916 | Process for producing defatted heparin tissue for heparin production An improved process for producing defatted heparin tissue is disclosed wherein frozen heparin-bearing tissue is particulated, thawed and warmed in a heat exchanger, fermented at temperatures ranging from about 60°-85° F. for 5 to 12 hours and subjected ... | 03/11/1980 |
| 4188467 | Process for tempering tissue for heparin production An improved method of tempering frozen heparin-bearing animal tissue is disclosed wherein the frozen tissue is particulated, thawed and warmed in a heat exchanger and fermented at temperatures ranging from about 60°-85° F. for 5-12 hours. Putrefaction a... | 02/12/1980 |
| 4175182 | Separation of high-activity heparin by affinity chromatography on supported protamine An affinity chromatography method for the separation of high-activity heparin from a mixture thereof with low-activity heparin. The method employs an affinity column of protamine coupled to a water-insoluble solid support material such as agarose, and a s... | 11/20/1979 |
| 4168377 | Process of preparing mixed heparin salts Mixed or simple heparin salt having a reduced amount of a selected metal ion alone or with another metal ion in a mixed heparin. A heparin salt having a reduced sodium content being essentially sodium free and having a selectively high calcium or other se... | 09/18/1979 |
| 4122250 | Separation of high-activity heparin by affinity chromatography An affinity chromatography method for the separation of high-activity heparin from a mixture thereof with low-activity heparin. The method employs an affinity column of DEAE-Sephadex and a series of sodium chloride-imidazole elution buffers (pH 6.5-7.5) v... | 10/24/1978 |
| 4119774 | Heparin purification method Crude clinically used heparin preparations having a low specific activity, for example, about 130 heparin units per milligram are purified by contacting such liquid crude heparin preparations with a gel matrix complexed with (i.e. having linked to it) ant... | 10/10/1978 |
| 4118485 | Non-thrombogenic medical article and a method for its preparation A medical article is made non-thrombogenic by means of a surface coating containing heparin. The heparinized surface is stabilized by being contacted first with a cationic surfactant of the primary amine type and, subsequently, with a dialdehyde.... | 10/03/1978 |
| 4082727 | Method for manufacture of non-coagulative organosilicone polymer A non-coagulative organosilicone resin is produced by causing an organosilicon compound containing an isocyanate group and possessing a siloxane-forming property to react with heparin in order to produce an organosilicon compound having a heparin residue ... | 04/04/1978 |
| 3932627 | Siver-heparin-allantoin complex Silver-heparin-allantoin complex and process for making same is disclosed. The silver-heparin-allantoin complex is prepared by a novel process in either powder or solution form. The silver-heparin-allantoin complex provides a non-thrombogenic, self-steril... | 01/13/1976 |