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Class 536/18.4 - Halogen containing


Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which contain halogen.
No. of patents: 153
Last issue date: 11/23/2010


      4  
NumberTitleIssue Date
4939244Pseudoaglycones of LL-E33288 antibiotics
Degradation products, termed pseudaglycones, of LL-E33288, BBM-1675, FR-900405, FR-900406, PD 114759, PD 115028, CL-1577A, CL-1577B, CL-1577D, CL-1577E and CL-1724 antibiotics/antitumor agents are disclosed anad described....
07/03/1990
4935504Epipodophyllotoxin glucoside 4'-acyl derivatives
Novel 4'-esters, 4'-carbonates and 4'-carbamates of 4'-demethylepipodophyllotoxin glucosides are disclosed. These agents exhibit antitumor activity in animals....
06/19/1990
4921948Sialosyl glyceride and process for producing the same
The present application discloses a new sialosyl glyceride having the following formula, which compound is useful as a remedy for nervous diseases, has an excellent compatability with the living bodies, and is easily producible. ##STR1## wherein...
05/01/1990
4920207Selected removal of trityl groups from trispa
2,3,4,3',4'-penta-O-acetyl sucrose (4-PAS), a key intermediate in the preparation of sucralose, is prepared by the selective removal of trityl groups from 6,1', 6'-tri-O-trityl-penta-O-acetyl sucrose (TRISPA) in which a catalytic amount of an aralkyl chlo...
04/24/1990
49180562-substituted arabinopyranosyl nucleosides and nucleotides
Novel arabinopyranosyl nucleoside derivatives having the heterocyclic moiety and fluorine at the 2' position of the sugar ring (pyranose configuration), which have antitumor, antiviral and antimicrobial properties, are prepared by condensation of a pyrimi...
04/17/1990
4914233Synthesis of beta-thymidine
A process is provided in which a mixture of alpha- and beta-anomers is converted selectively to the desired beta-thymidine. The process involves the following steps: (a) converting a mixture of alpha- and beta-anomers of tetra-O-acylribofuranose to tri-O-...
04/03/1990
4879377Nucleoside process
Process for producing 1-halo-2-deoxy-2-fluoroarabinofuranoside derivatives bearing protective ester groups from 1,3,5-tri-O-acylribofuranose; the 1-halo compounds are intermediates in the synthesis of therapeutically active nucleosidic compounds....
11/07/1989
48717762,5-anhydro-1,6-dihalo-1,6-dideoxy-D-mannitol
A novel fructose analog is disclosed which has been found to modify the food intake of mammals. If administered during the diurnal fasting period, the mammals increase their food intakes. If administered during the diurnal feeding period, food intake is d...
10/03/1989
4868289Glycosidic derivatives
O-glycosidic compounds useful for therapy or prophylaxis of a wide variety of diseases, for diagnostic use or as research chemicals. Another object of the present invention is to provide a method for preparing the O-glycosidic compounds....
09/19/1989
4857640Process and reagent for the determination of ଱-amylase
A process and a reagent for the determination of ଱-amylase involve enzymatic splitting of an ଱-amylase substrate in the presence of ଱-glucosidase and ଲ-glucosidase and measurement of a fission product. As substrate, there is used a...
08/15/1989
4826962Tetrachlororaffinose and its use in the preparation of sucralose
The novel chlorinated sugar O-଱-D-6-chloro-6-deoxygalactopyranosyl-(1.fwdarw.6)-଱-D-4-chlo ro-4-deoxygalactopyranosyl-(1.fwdarw.2)-ଲ-D-1, 6-dichloro-1, 6-dideoxyfructofuranoside (TCR) can be used to prepare sucralose by incubating th...
05/02/1989
4826966Radioiodinated branched carbohydrates
A radioiodinated branched carbohydrate for tissue imaging. Iodine-123 is stabilized in the compound by attaching it to a vinyl functional group that is on the carbohydrate. The compound exhibits good uptake and retention and is promising in the developmen...
05/02/1989
4820692Methylthioribose analogs, their preparation and use as medicinal agents and biocides
Compounds of the formula: ##STR1## wherein R is H, Cl, F, Br, I or R1 S--, in which R1 is C1 -C10 linear or branched chain alkyl or halogenated linear or branched chain alkyl, and wherein R2, R
04/11/1989
4801700Process for the preparation of 1,6-dichloro-1,6-dideoxy-ଲ-D-fructofuranosyl-4-chloro-4-deoxy-଱ -
A process for the preparation of 1,6-dichloro-1,6-dideoxy-ଲ-D-fructofuranosyl-4-chloro-4-deoxy-଱ -galactopyranoside comprising the steps of (a) reacting sucrose with a tritylating agent; (b) acetylating the tritylated reaction product; (c) ...
01/31/1989
4797477Process for preparing sialic acid derivatives
The present invention relates to a new process for preparing 3-O-(sodium(5-acetamide-3,5-dideoxy-alpha-D-glycero-D-galacto-2-noneuro pyranosyl)onate-1,2-di-O-tetradecyl-Sn-glycerol (3) consisting essentially of hydrolyzing a 3-O-(C1-5 alky...
01/10/1989
4794178Process for the production of 18 F-labeled organic compounds by nucleophilic substitution
Organic compounds labeled with no-carrier-added fluorine 18 are processed yield a compound having a formula in the form of 18 F-R through a nucleophilic substitution reaction. The process has a series of steps. The first step of the process re...
12/27/1988
4783526Chlorination of carbohydrates and other alcohols
Chlorination of carbohydrates and alcohols utilizing a chlorinating reagent selected from triphenylphosphine oxide/thionyl chloride, thiphenylphosphine oxide/phosgene, triphenylphosphine sulfide/thionyl chloride and triphenylphosphine sulfide/phosgene....
11/08/1988
4751290Sialosylcerebrosides
This invention provides a novel compound having a formula such as ##STR1## This invention also provides a process for preparing such a compound....
06/14/1988
4751291Process for the preparation of glycosyl fluorides protected on the oxygen
Glycosyl halides which are O-acylated or O-alkylated at least in the 2-position are transhalogenated with alkali metal hydrogen difluorides in a polar-aprotic solvent and, if appropriate, the product is anomerized with the addition of less than the stoich...
06/14/1988
4739043Method for the synthesis of alkyl, cycloalkyl or alcenyl aldosides or polyaldosides
The process comprises the action of a saturated aliphatic or cycloaliphatic alcohol or an aliphatic or cycloaliphatic alcohol comprising a double ethylenic bound not situated in alpha of the hydroxyl group with an aldose, aldoside or polyaldoside in the s...
04/19/1988
4692434Difluoro antivirals and intermediate therefor
A 2,2-difluoro-2-desoxycarbohydrate is used to prepare antiviral nucleosides....
09/08/1987
46833143-O-benzyl-2,4,6-tridooxy-6-iodo-alpha-D-erythro-hexopyranide useful for preparing inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase
Totally synthetic analogs of the known inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase, compactin and mevinolin, are prepared from a chiral synthon derived from D-glucose which has the same chirality as the natural products....
07/28/1987
4675391Glycoside derivatives
This invention provides a novel compound having a formula such as ##STR1## This invention also provides a process for preparing such a compound. The novel compound has excellent immunological activity....
06/23/1987
4617386Process for the production of 18 F-2-deoxy-2-fluoro-D-glucose
Process for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding 18 F-compound in which methyl 4,6-O-benzylidine-3-O-methyl-2-O-trifluoromethanesulfonyl-ଲ-D-mannopy ranoside is reacted with a triflating reagent, the resulting...
10/14/1986
45540105-Deoxy-3-O-arylmethyl or substituted arylmethyl-1,2-O-substituted-alkylidene-alpha-D-xylofuranose herbicide derivatives
5-Deoxy-3-O-arylmethyl or substituted aryl-methyl-1,2-O-substituted-alkylidene or cycloalkylidene-alpha-D-xylofuranose and 5-C-alkyl, alkylidenyl and alkenyl derivatives thereof. The compounds are useful as herbicides and plant growth regulators....
11/19/1985
4534785Herbicidal 5-deoxy-3-O-arylmethyl or substituted arylmethyl-1,2-O-ethylene-alpha-D-xylofuranose derivatives
5-Deoxy-3-O-arylmethyl or substituted arylmethyl-1,2-O-ethylene-alpha-D-xylofuranose and 5-C-alkyl, alkylidenyl and alkenyl derivatives thereof. The compounds are useful as herbicides and plant growth regulators....
08/13/1985
4430247Process for preparing an oxyalkylated product
An oxyalkylated product useful for making polyurethane foams is prepared by reacting an alkylene oxide with a heated mixture of a phenol and a non-phenolic active hydrogen compound, at least one of which can be halogenated, in the presence of a catalyst c...
02/07/1984
4429118Methyl 3-azido-4-C-cyano-2,3,4,6-tetradeoxy-଱-D-arabino-hexopyranoside and processes for its preparation
Disclosed is methyl 3-azido-4-C-cyano-2,3,4,6-tetradeoxy-଱-D-arabino-hexopyranoside and processes for its preparation from methyl 3-azido-2,3,6-trideoxy-଱-D-arabino-hexopyranoside via the 4-bromo-4-deoxy intermediate; wherein the two inve...
01/31/1984
44291195-Deoxy-3-O-arylmethyl or substituted arylmethyl-1, 2-0-alkylidene-alpha-D-xylofuranose herbicide derivatives
5-Deoxy-3-0-arylmethyl or substituted arylmethyl-1,2-0-alkylidene-a-D-xylofuranose and 5-C-alkyl and alkenyl derivatives thereof. The compounds are useful as herbicides and plant growth regulators....
01/31/1984
4415731Process for the preparation of methyl 2,6-dideoxy-଱-D-arabino-hexopyranoside
Disclosed is a process for preparing methyl 2,6-dideoxy-଱-D-arabino-hexopyranoside from methyl 2-deoxy-଱-D-glucopyranoside....
11/15/1983
4393203Process of preparing alkylpolysaccharides
Long chain fatty alcohols can be removed from alkylpolysaccharide products in thin film evaporators to achieve fatty alcohol levels of less than about 2% without excessive discoloration of the alkylpolysaccharide....
07/12/1983
4259324Immunologic adjuvant thio glycoside compounds and compositions
Compounds of the formulae Y--R wherein Y is 1-thio-ଲ-L-fucose, 1-thio-ଲ-D-galactose or 1-thio-ଲ-lactose and R is 2-(1-adamantyl)ethyl, 3-[(p-tetrafluorophenethyl)phenyl]propyl, 6-(5-cholesten-3ଲ-yloxy)hex-3-ynl, oleyl, or hexadecyl...
03/31/1981
4192868Novel aryl-hexafuranosides and processes for their preparation
The invention relates to processes for the preparation of novel aryl-hexafuranosides of the formula ##STR1## in which R1 is lower alkyl or cycloalkyl and R2 is hydrogen, lower alkyl or acyl, or R1 and R2 to...
03/11/1980
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