...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 5393744 | Glucosyl phosphotriesters of thymidine A compound having the following formula I: ##STR1## in which: R' represents a hydrogen atom or an azido group, alc represents an alkyl group of 1 to 4 carbon atoms, an alkoxy group of 1 to 4 carbon atoms or an amino group.... | 02/28/1995 |
| 5386019 | Synthesis of inhibitors of calmodulin-mediated enzymes including KS-501, KS-502 and their enantiomers The total synthesis of a group of compounds with inhibitory effects on calmodulin-mediated enzyme activities has been accomplished. Among these synthesized compounds are KS-501 and KS-502. Other compounds that have been synthesized by the described scheme... | 01/31/1995 |
| 5378833 | Method for preparing galacto-oligosaccharides A process of preparing galacto-oligosaccharides comprising the step of heating up lactose, or, a mixture of lactose and galactose under presence of an inorganic acid as a catalyst in an anhydrous powder condition.... | 01/03/1995 |
| 5326405 | Solid lactulose The present invention is concerned with a method for the preparation of crystal-water-free crystalline lactulose by subjecting an aqeous solution or suspension of lactulose to simultaneous reduction of the water content by evaporation and continuous stirr... | 07/05/1994 |
| 5298611 | Sucralose pentaester production A process for producing substantially pure sucralose pentaester from a mixture of 6-O-acyl-4,1' ,6' -trichloro-4,1',6'-trideoxygalactosucrose in a reaction medium comprising a tertiary amide, wherein said process comprises the steps of: (a) recovering the... | 03/29/1994 |
| 5238826 | Process for manufacturing xylose Process for manufacture of D-xylose characterized by the fact that: in a first step, syrup of D-xylulose is subjected to an enzymatic isomerization in M3 providing a mixture of D-xylose and D-xylulose, in a second step, the abovesaid mixture is subjected... | 08/24/1993 |
| 5162517 | Process for the preparation of epimer-free sugar alcohols from the group consisting of xylitol, sorbitol (D-glucitol), 4-O-ଲ-D-galactopyranosyl-D-glucitol and 4-O--D-glucopyranosyl-D-sorbitol The sugar alcohols given in the title can be prepared in epimer-free form from the corresponding sugars by catalytic hydrogenation in aqueous solution using hydrogen, the hydrogenation being carried out continuously at 100-500 bar of H2 and 60Â... | 11/10/1992 |
| 5136031 | Chlorination of sugars A process for the chlorination of sucrose or a derivative thereof, comprises reaction of the sucrose or derivative thereof with thionyl chloride and a nitrogen base at a ratio of about 1 molar equivalent (ME) of thionyl chloride and about 1 ME of base for... | 08/04/1992 |
| 5128323 | Composition having anti-endotoxic activity The invention relates to pharmaceutical compositions having antiendotoxic activity, comprising as the active component a fraction which can be isolated from lactulase syrup by means of absorption at a sulphonated polystyrene cation resin in the Ca2+ | 07/07/1992 |
| 5122601 | Synthesis of 2,3,3',4,4'-penta-o-methylsucrose A process for manipulating any polyhydroxy compound bearing two or more primary and secondary hydroxyl groups to expose only the primary hydroxyl groups, while blocking all interfering secondary hydroxyl groups as their methyl or other alkyl ethers. More ... | 06/16/1992 |
| 5078796 | Process for manufacturing tagatose A process is disclosed for the synthesis of D-tagatose by isomerizing a mixture containing D-galactose with a metal hydroxide in the presence of a catalyst at a relatively low temperature to form an intermediate metal hydroxide-D-tagatose complex, and the... | 01/07/1992 |
| 5071530 | Method of manufacturing lactulose For the manufacture of lactulose, an alkaline aqueous solution of lactose and borax is prepared and heated at a temperature above 80° C. The lactulose is separated from the resulting conversion products. Apart from the borax, no alkalizing material is ad... | 12/10/1991 |
| 4960762 | Chiral two-phase system and method for resolution of racemic mixtures and separation of diastereomers A chiral two-phase system for resolution of racemic mixtures, or for separation of diastereomers, is disclosed. The system comprises two immiscible liquid phases and one or more enantioselectively binding chiral components, each of which is substantially ... | 10/02/1990 |
| 4959467 | Control of product selectivity in the addition of HCN to arabinose Hydrogen cyanide addition to a monosaccharide results in a mixture of product cyanohydrins whose ratio can be changed by conducting the hydrogen cyanide addition in the presence of an agent which forms a complex with the monosaccharide. It is preferred to... | 09/25/1990 |
| 4957564 | Process for preparing lactulose from lactose by epimerization with sodium aluminate A process for preparing lactulose from lactose in which an aqueous lactose mixture is reacted with a sodium aluminate solution and the solution obtained is continuously neutralized by feeding this solution and a sulphuric acid solution to a reactor simult... | 09/18/1990 |
| 4920207 | Selected removal of trityl groups from trispa 2,3,4,3',4'-penta-O-acetyl sucrose (4-PAS), a key intermediate in the preparation of sucralose, is prepared by the selective removal of trityl groups from 6,1', 6'-tri-O-trityl-penta-O-acetyl sucrose (TRISPA) in which a catalytic amount of an aralkyl chlo... | 04/24/1990 |
| 4815445 | Solid catalysts for epimerization of aldoses; continuous interconversion of epimeric sugars Anion exchange resins which have been exchanged with molybdate at acid pH are effective catalysts for epimerizing compounds with the structural unit: ##STR1## Cheif among these are aldoses, especially aldopentoses and aldohexoses, as well as som... | 03/28/1989 |
| 4801700 | Process for the preparation of 1,6-dichloro-1,6-dideoxy-ଲ-D-fructofuranosyl-4-chloro-4-deoxy- - A process for the preparation of 1,6-dichloro-1,6-dideoxy-ଲ-D-fructofuranosyl-4-chloro-4-deoxy- -galactopyranoside comprising the steps of (a) reacting sucrose with a tritylating agent; (b) acetylating the tritylated reaction product; (c) ... | 01/31/1989 |
| 4786722 | D-tagatose as a low-calorie carbohydrate sweetener and bulking agent There is disclosed a process for the preparation of a sweetened edible formulation in which the sweetening agent is less calorific than sucrose which comprises the step of mixing a foodstuff with an amount sufficient to sweeten the foodstuff of D-tagatose... | 11/22/1988 |
| 4783526 | Chlorination of carbohydrates and other alcohols Chlorination of carbohydrates and alcohols utilizing a chlorinating reagent selected from triphenylphosphine oxide/thionyl chloride, thiphenylphosphine oxide/phosgene, triphenylphosphine sulfide/thionyl chloride and triphenylphosphine sulfide/phosgene.... | 11/08/1988 |
| 4778531 | Epimerization of sugars, in particular of D-arabinose to D-ribose Pentoses and hexoses are epimerized by heating sugar dissolved in a solvent in the presence of a molybdenum(VI) compound, by an improved process in which, for the preparation of a sugar having cis OH groups in the 2- or 3-position, of the formula Ia or Ib... | 10/18/1988 |
| 4684720 | Process for the preparation of a mixture of -D-glucopyranosido-1,6-mannitol and -D-glucopyranosido-1,6-sorbitol from -D-glucopyranosido-1,6-fructose In the preparation of a mixture of -D-glucopyranosido-1,6-mannitol and -D-glucopyranoside-1,6-sorbitol by catalytically hydrogenating -D-glucopyranosido-1,6-fructose in aqueous solution with hydrogen under increased pressure and at el... | 08/04/1987 |
| 4663449 | Process for effecting aldose to ketose conversion A process for the conversion of an aldose, or a substituted aldose, to a ketose, or a substituted ketose, in an aqueous reaction mixture containing a halide of a metal from Group II of the Periodic Table at a concentration in the range 0.5 molar to satura... | 05/05/1987 |
| 4623721 | Synthesis of L-fructose and derivatives thereof It is disclosed that L-fructose can be produced in high yield from L-sorbose. The process involves the inversion of the hydroxyl groups on carbon atoms C3 and C4 of L-sorbose to produce L-fructose. This inversion can be accomplished in simple, commercial ... | 11/18/1986 |
| 4602086 | Method of producing solution containing D-ribose A D-ribose-containing solution is produced in a high epimerization ratio, such as 60-94%, by epimerizing D-arabinose dissolved in an adequate solvent in the presence of a molybdic acid ion and a boric acid compound. The solution is useful as an inexpensiv... | 07/22/1986 |
| 4581447 | Process for making a mixture of L-glucose and L-mannose A process converting L-arabinose to L-fructose in high yield and selectivity is described. The success of the process depends upon careful pH control during cyanohydrin formation from L-arabinose and its subsequent selective hydrogenation, the choice of h... | 04/08/1986 |
| 4575549 | Process for the preparation of fructose 1,6 diphosphate acid The process according to the invention provides, for the purification of FDPH4 -containing solutions, for a double chromatography combined with the molecular filtration. There are thus obtained concentrated and highly pure solutions containing ... | 03/11/1986 |
| 4536221 | Process for preparing lactulose from lactose, in the form of a syrup or a crystalline product A process for preparing lactulose from lactose, in the form of a concentrated syrup or high purity crystals, for pharmaceutical use or for use as a sweetener. The process is characterized by using as the lactose epimerizing agent a mixture of equal parts ... | 08/20/1985 |
| 4440854 | Preparation of 6-deoxy-D-fructose and 6-deoxy-L-sorbose 6-Deoxy-D-fructose and 6-deoxy-L-sorbose, useful starting materials for the synthesis of 4-hydroxy-2,5-dimethyl-2,3-dihydrofuran-3-one, are obtained from fructose-1,6-diphosphate by a reaction with lactaldehyde, in the presence of an enzymatic system comp... | 04/03/1984 |
| 4362869 | Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose is prepared by a process including the steps of: (a) isomerizing 2,3,4,3',4'-penta-O-acetyl sucrose to 2,3,6,3',4'-penta-O-acetyl sucrose; (b) chlorinating the isomerized acetate at the 4,1' and 6'-positions; an... | 12/07/1982 |
| 4337171 | Organic bound adsorbents An adsorbent comprising a crystalline aluminosilicate and cation exchange resin mixture, method of manufacture of the adsorbent and process for separating a component from a feed blend comprising an aqueous solution of a mixture of different components, s... | 06/29/1982 |
| 4273922 | Ketose sugars from aldose sugars Ketose sugars are prepared in high yield by reacting an aldose sugar and boric acid in aqueous medium in the presence of a tertiary or quaternary amine.... | 06/16/1981 |
| 4133948 | Monosaccharides and products resulting therefrom The invention provides novel compounds of the formula: ##STR1## wherein B is - or ଲ- and represents a hydrocarbyl group in which the -carbon atom is activated by a suitable blocked or unblocked functional group rendering it suscep... | 01/09/1979 |
| 4083881 | Process for preparing D-mannitol A D-glucose solution is added molybdic acid compound thereto and heated at a temperature of 110°-160° C with pH 2.0-4.5 to perform epimerizing reaction of D-glucose, and thereby 30-36%, based on the D-glucose, of D-mannose is formed. To the epimerized m... | 04/11/1978 |
| 4083733 | Method of producing beta-lactose To alpha-lactose or an alpha-lactose-containing substance is added a small amount of water and the resulting mixture is subjected to extrusion from a screw extruder under pressure, thereby converting the alpha-lactose into beta-lactose. The beta-lactose o... | 04/11/1978 |
| 4069104 | Conversion of aldose to ketose in the presence of oxyanions or mixed oxyanions of tin or germanium A process for converting aldoses or derivatives thereof into ketoses or derivatives thereof which takes place in the presence of oxyanions or mixed complex oxyanions of germanium or tin which form stronger complexes with the ketoses or derivatives thereof... | 01/17/1978 |
| 4029878 | Process for preparing mannitol from glucose Mannose is produced from a concentrated solution of glucose or polymers of glucose in the presence of a catalyst containing hexavalent molybdenum. Subsequent hydrogenation of the product in order to produce mannitol is also disclosed.... | 06/14/1977 |