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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8173798 | Vaccine The invention relates to a vaccine for the treatment of disease caused by Neisseria, the vaccine including one or more immunogenic components for Neisseria serogroups, as well as antibodies to the immunogenic components and methods of preventing and tr... | 05/08/2012 |
| 8071759 | Water soluble cholesterol derivatives Four novel water soluble cholesterol derivative compounds are disclosed. These compounds have various applications in studies of membrane proteins, including drug screening and studies of receptor stability and folding. In one aspect the water soluble cholesterol de... | 12/06/2011 |
| 8049004 | Processes for making ethersuccinylated hydroxyl polymers Processes for making ethersuccinylated hydroxyl polymers are provided. ... | 11/01/2011 |
| 7964561 | Protein formulations for use at elevated temperatures Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability... | 06/21/2011 |
| 7868168 | High viscosity xanthan polymer preparations Increasing the molecular length of xanthan polymer makes a higher viscosity xanthan composition. Xanthan with higher specific viscosity characteristics provides more viscosity at equivalent concentration in food, industrial and oilfield applications. Methods for inc... | 01/11/2011 |
| 7767806 | Hyaluronic acid modification products and drug carriers using them A hyaluronic acid modification product includes a polymer bonded to hyaluronic acid, the polymer being polylactic acid, polyglycolic acid or lactic acid-glycolic acid copolymer, providing a drug carrier which efficiently encapsulates low molecular weight drugs and p... | 08/03/2010 |
| 7763723 | Polysaccharide and composition from and use thereof The invention relates to polysaccharide extracted from Antrodia camphorata and the method for preparing the polysaccharide. The invention also relates to compositions and methods for hepatoprotective effect. ... | 07/27/2010 |
| 7745616 | Bead for enantiomeric isomer resolution and process for producing the same There is provided a process for producing beads for enantiomeric isomer resolution with a satisfactory separation efficiency. The beads for enantiomeric isomer resolution include a polysaccharide derivative, in which the polysaccharide derivative has a structure cro... | 06/29/2010 |
| 7485719 | Crosslinkable polysaccharide derivative, process for producing the same, crosslinkable polysaccharide composition, and medical treatment material A crosslinkable polysaccharide derivative which has in the side chain of polysaccharide at least one active ester group reactive with an active hydrogen-containing group and which forms a crosslinked product through covalent bond between the active ester group and t... | 02/03/2009 |
| 7456276 | Peptide purification by means of metal ion affinity chromatography A polymer substrate functionalized with a functionality comprising at least one cyclic, metal ion coordinating ligand group, the cyclic ligand group comprising at least 3 metal ion coordinating donor atoms independently selected from the group consisting of N, O and... | 11/25/2008 |
| 7442528 | Modified alternan Four new Penicillium spp. isolates (NRRL 21966, NRRL 21967, NRRL 21968, and NRRL 21969) are capable of essentially quantitative conversion of native alternan to a polymeric modified form having a lower apparent molecular weight than native alternan. A fifth i... | 10/28/2008 |
| 7439352 | Process for the production of anhydrosugar alcohols A process is provided for the preparation of anhydrosugar alcohols. The process involves heating a sugar alcohol or a monoanhydrosugar alcohol starting material in the presence of an acid catalyst, and subsequent purification of the anhydrosugar alcohol. In some emb... | 10/21/2008 |
| 7417109 | Polymers for delivering nitric oxide in vivo Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is prepared by reacting a polythiolated polymer with a nitro... | 08/26/2008 |
| 7402575 | Methods of treating inflammation Methods and compositions for treating myocardial dysfunction or inflammation are described. The methods of the invention involve administering an agent that can inhibit lysozyme to an animal in need thereof. Preferred lysozyme inhibitors include TAC and chitobiose. | 07/22/2008 |
| 7396924 | Building additives based on purified hydroxyalkyl guar The present invention relates to highly hydroxyalkylated, glyoxal crosslinked, purified hydroxyalkyl guar useful as additive in the building industry, and to a method for its preparation. ... | 07/08/2008 |
| 7390644 | Production of exopolysaccharides unattached to the surface of bacterial cells The present invention is directed to a Sphingomonas bacteria and a method of producing exopolysaccharides by culturing a Shpingomonas bacteria in a fermentation broth for a time and temperature effective for providing a sphingan exopolysaccharide in a ... | 06/24/2008 |
| 7385052 | Process for the production of multiple cross-linked hyaluronic acid derivatives The present invention relates to a process for the production of cross-linked hyaluronic acid (HA) derivatives, in particular multiple, e.g. double cross-linked hyaluronic acid derivatives. The invention also provides novel cross-linked HA derivatives, products cont... | 06/10/2008 |
| 7365191 | Type of oligosaccharides and their sulfate derivatives This invention involves a type of oligosacoharides and its their sulfate derivatives. The backbone of the oligosaccharides consists of 4 to 14 glucose residues, while the side chains contain 0 to 4 glucose residues. There are at least one 1->3α linkage and β-(1->3... | 04/29/2008 |
| 7365190 | Crosslinked polysaccharide, obtained by crosslinking with substituted polyethylene glycol, as superabsorbent New crosslinked polysaccharides useful as absorbents or superabsorbents alone or in a mixture are obtained by reacting polysaccharides (preferably containing carboxylates groups) with at least one crosslinker selected in the group constituted by activated polyethyle... | 04/29/2008 |
| 7365192 | Preparation method of valienamine from acarbose and/or acarbose derivatives using trifluoroacetic acid The present invention provides a preparation method of valienamine from acarbose or acarbose derivatives using organic acid TFA (trifluoroacetic acid). By using the method of the present invention, valienamine, the core precursor of voglibose which is a strong retar... | 04/29/2008 |
| 7358346 | C-glycosides, uses thereof The present invention relates to novel C-glycoside compounds of given absolute configuration, to a process for synthesising them and to compositions containing them. The invention also relates to the cosmetic use of these C-glycoside compounds as agents to stimulate... | 04/15/2008 |
| 7355039 | Building additives based on purified hydrophobically modified hydroxyalkyl guar The present invention relates to highly hydroxyalkylated, glyoxal crosslinked, purified hydrophobically modified hydroxyalkyl guar useful as additive in the building industry, and to a method for its preparation. ... | 04/08/2008 |
| 7345166 | Water soluble biodegradable polymeric photocatalysts Novel antenna polymers characterized by a polymeric background of a biodegradable water soluble polymer and chromophores chemically bonded to the polymeric background have been found to be useful as photocatalysts in aqueous media. On completion of the desired photo... | 03/18/2008 |
| 7345117 | Sulphated hyaluronic acid and sulphated derivatives thereof covalently bound to polyurethanes, and the process for their preparation The present invention relates to the synthesis of a haemocompatible polymer, consisting of a polyurethane bound covalently to sulphated hyaluronic acid. These sulfated derivatives have anticoagulative, non-thrombogenic, antiviral and anti-inflammatory properties. Th... | 03/18/2008 |
| 7341981 | Spray composition having a deposition control agent A spray composition includes an aqueous spray medium, an active ingredient, and a deposition control agent, wherein: the composition comprises at least one surfactant, and the deposition control agent is selected f... | 03/11/2008 |
| 7335627 | Polymeric alkylpolyglycoside carboxylates The products of the invention are polymers of carboxylated alkylpolyglycosides. The products are very mild surfactants that are useful in personal care applications. ... | 02/26/2008 |
| 7332173 | Group A streptococcal polysaccharide immunogenic compositions and methods This invention provides a novel immunogenic composition and vaccine, processes for producing them and methods for immunization against infections and disease caused by group A Streptococci. The compositions include group A streptococcal polysaccharide covalently lin... | 02/19/2008 |
| 7309697 | Cyclic maltosylmatose An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for produci... | 12/18/2007 |
| 7304148 | Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain, and processes for producing these An asparagine-linked α2,3-oligosaccharide having undeca- to hepta-saccharides, an asparagine-linked α2,6-oligosaccharide having undeca- to hepta-saccharides and containing fluorine and an asparagine-linked oligosaccharide derivative containing at least one fucose ... | 12/04/2007 |
| 7301018 | Probe for mass spectrometry of liquid sample Disclosed is a probe for mass spectrometry of liquid samples, which may effectively ionize the sample without adding a protic solvent to the mobile phase in the ionization method in mass spectrometry of liquid samples. The probe according to the present invention ha... | 11/27/2007 |
| 7288608 | Degradable thiol-ene polymers A thiol-ene polymeric material is disclosed. The material is produced by the photopolymerization of reactants having thiol and olefin moieties. The material can incorporate encapsulated components, including cells. Additionally, the material can be derivatized by re... | 10/30/2007 |
| 7268100 | Shale inhibition additive for oil/gas down hole fluids and methods for making and using same An under-balanced drilling fluid additive is disclosed which reduces reactive shale and/or clay swelling during under-balanced drilling operations, where the additive includes an effective amount of a choline salt. A method for under-balanced drilling is also disclo... | 09/11/2007 |
| 7265098 | Polyacid/polyalkylene oxide gels and methods for their delivery The present invention relates to improved methods for delivering bioadhesive, bioresorbable, anti-adhesion compositions. Antiadhesion compositions can be made of intermacromolecular complexes of carboxyl-containing polysaccharides, polyethers, polyacids, polyalkylen... | 09/04/2007 |
| 7262179 | Wound care compositions Compositions for the treatment of wounds and skin injuries are described. The compositions, which include gellan gum, increases in viscosity once applied to the wound to form an immobile gel. The composition may be in sprayable form or dispersed in an aqueous soluti... | 08/28/2007 |
| 7259152 | Methods and compositions using sulodexide for the treatment of diabetic nephropathy The present invention provides oral formulations of Sulodexide for the treatment of diabetic nephropathy in patients with both insulin dependent and non-insulin dependent diabetes mellitus. Oral formulations containing doses adapted for administration to obtain a re... | 08/21/2007 |
| 7252828 | Polysaccharide vaccine for infections The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. Th... | 08/07/2007 |
| 7253152 | Electrically conductive polymeric biomaterials, the process for their preparation and the use thereof in the biomedical and healthcare field The present invention concerns the preparation of composite biomaterials constituted by hyaluronic acid and the derivatives thereof in combination with polymers that have electrically conductive properties. In particular, the methods of preparing biomedical devices ... | 08/07/2007 |
| 7253278 | Purification process for manufacturing a high pure acarbose A process for purifying and preparing highly pure acarbose from acarbose-containing fermentation broth. The acarbose is purified through steps of alcohol precipitation, a strongly acidic cation exchanger chromatography and an immobolized enzyme affinity chromatograp... | 08/07/2007 |
| 7244830 | Glycopolymers and free radical polymerization methods A glycopolymer composition is provided comprising glycopolymer molecules having a polymer backbone; a first pendent unit comprising a linking group connected to said polymer backbone and a saccharide moiety connected to said linking group, optionally a second penden... | 07/17/2007 |
| 7230096 | Inhibitors against galectins The present invention relates to novel compounds, the use of said compounds as a medicament as well as for the manufacture of a medicament for treatment of disorders relating to the binding of galectin to receptors in a mammal. Said galectin is preferably a galectin... | 06/12/2007 |
