Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 5248675 | Polysulfate of cyclodextrin derivative and process for preparing the same A polysulfate of a cyclodextrin in which at least one of 6 to 8,D-glucose units constituting the cyclodextrin has been replaced by a unit represented by Formula (1): ##STR1## wherein R is a group represented by the formula: ##STR2## where R... | 09/28/1993 |
| 5244881 | Compositions based on imipyramine The invention provides new inclusion compounds based on imipramine and cyclodextrin and pharmaceutical compositions which can be administered orally and are based on these new inclusion compounds.... | 09/14/1993 |
| 5241059 | Cyclodextrin derivatives Cyclodextrin derivatives having at least one group selected from among a sulfonic acid group, a sulfonic acid salt group, an ammonium salt group, a phosphoric acid group, a carboxyl group, a carboxylic acid salt group and a hydroxyl group are disclosed. T... | 08/31/1993 |
| 5238927 | Hydrolytic stabilizer for unstable organic ions Storage-stable aqueous solutions of hydrolytically unstable organic ionic compounds and cyclodextrins, which cyclodextrins are capable of forming hydrolytically stable inclusion complexes with the ionic compounds. Storage-stable rapidly solvated organic i... | 08/24/1993 |
| 5231089 | Method of improving oral bioavailability of carbamazepine The invention provides a method for improving the oral bioavailability of carbamazepine by administering per os, to a warm-blooded animal in need of carbamazepine therapy, a therapeutically effective amount of carbamazepine complexed with cyclodextrin sel... | 07/27/1993 |
| 5229370 | Water soluble branched beta cyclodextrin steroid complex A complex of branched beta cyclodextrin and steroid is formed by mixing a steroid and a branched beta cyclodextrin together in water for a period of about 4 to 24 hours under ambient conditions. The solubility of the steroid is increased about 95 times by... | 07/20/1993 |
| 5227372 | Method for retaining ophthalmological agents in ocular tissues A method for retaining ophthalmological agents in ocular tissues is provided comprising complexing an ophthalmological drug or reagent with a sulfated glucan sulfate such as cyclodextrin sulfate and contacting the complex so formed with the ocular tissue.... | 07/13/1993 |
| 5223295 | Process for the elimination of steroid compounds contained in substance of biological origin The present invention relates to a novel process for the elimination of steroid compounds contained in a substance of biological origin by complexing the steroidal compounds by means of a cyclodextrin, in an aqueous medium, under agitation at a temperatur... | 06/29/1993 |
| 5221735 | Cyclodextrin-polyene inclusion complexes Inclusion complexes of the polyenes apocarotenal and lycopene in a cyclodextrin as well as their manufacture are described. The inclusion complexes are soluble in water, alcohol or water/alcohol mixtures.... | 06/22/1993 |
| 5208316 | Cyclodextrin polymer and cyclodextrin membrane prepared using said polymer Provided are a cyclodextrin polymer containing cyclodextrin in the backbone chain of a high-molecular weight compound selected from a polyurethane, a polyurea, an unsaturated polyester, a polyester, a polycarbonate, a polyamide and a polysulfone, as well ... | 05/04/1993 |
| 5206025 | Porous pharmaceutical form and its preparation New porous, unitary freeze-dried pharmaceutical form, of homogeneous appearance, consisting of: a) an inclusion compound comprising: one or optionally more active substances, a predetermined quantity of cyclodextrin, optionally an additive facilitating inclusion, b... | 04/27/1993 |
| 5206224 | Treatment of male hormone related diseases by cyclodextrins and their derivatives A method for treatment of diseases having an etiology based on or accompanied by excess male hormone which comprises administering, to a subject in need of such treatment, a cyclodextrin or a derivative thereof in an amount effective in such treatment.... | 04/27/1993 |
| 5200517 | Inclusion-complexing agent for use in isolation of xylene isomer(s) and/or ethylbenzene A mixture of xylene isomers or a mixture of a xylene isomer(s) and ethylbenzene is brought into contact with at least one specific substituted -cyclodextrin to form an inclusion complex(es) of the substituted -cyclodextrin with a xylene isom... | 04/06/1993 |
| 5198430 | Inclusion complexes with silybinin, their preparation and pharmaceutical compositions containing them The invention relates to inclusion complexes of Silybinin with a cyclodextrin selected from the group consisting of -, ଲ- and γ-cyclodextrin and a suitable derivative thereof and to the method for the preparation thereof. The inclusion compl... | 03/30/1993 |
| 5198429 | Substituted cyclodextrins and process for chromatographic separation of chiral organic compounds Substituted cyclodextrins of the general formula ##STR1## in which R2 and R6 mean straight-chain or branched alkyl or alkenyl groups with 1 to 8 carbon atoms or cycloalkyl groups with 5 to 8 carbon atoms which can be the same or... | 03/30/1993 |
| 5196406 | Cyclodextrin complex of fumagillin derivative A complex of a fumagillin derivative represented by the general formula: ##STR1## wherein R1 is hydrogen; R2 is halogen, N(O)mR5 R6, N+ R5 R6 R7.X.sup.-, S(O)nR5 | 03/23/1993 |
| 5189149 | Method for the production of complexes of long chain polyunsaturated fatty acids and their derivatives, with cyclodextrins, and the resulting complexes A method for the production of a complex formed by a long chain polyunsaturated fatty acid, a salt of it, alkyl ester C1 -C3 or glyceride, or a mixture thereof, with a cyclodextrin, and the resulting complex.... | 02/23/1993 |
| 5183809 | Cyclodextrin polymers and cyclodextrins immobilized on a solid surface Polyionic derivatives of cyclodextrin polymers and cyclodextrins immobilized on a solid surface are disclosed. Compositions and methods for separating a molecular species, including but not limited to a biologically active protein, from a mixture, for the... | 02/02/1993 |
| 5182270 | Stabilizing preparation for thymoxamine Experiments have been performed which test the stability of thymoxamine in aqueous solution at room temperature and above. It was determined that dimethyl-beta-cyclodextrin slows the hydrolysis degradation of thymoxamine while other beta-cyclodextrin anal... | 01/26/1993 |
| 5180716 | Cyclodextrin complexes for neuraxial administration of drugs A method of delivering a drug to a patient, comprising administering said drug to the neuraxis of said patient in the form of a complex between said drug and a cyclodextrin, the cyclodextrin comprising at least one substituent to reduce crystallization of... | 01/19/1993 |
| 5173481 | Preparation of specifically substituted cyclodextrins A process for producing monosubstituted alpha-, beta-, and gamma-cyclodextrins includes the step of condensing an excess of a cyclodextrin with an epoxide under alkaline conditions. A process for increasing the solubility of cyclodextrins includes the ste... | 12/22/1992 |
| 5164380 | Process for preparing piroxicam/cyclodextrin complexes, the products obtained and their pharmaceutical compositions A process for preparing complexes of piroxicam with cyclodextrins in which the two components in the powder state are premixed and then co-ground in a high energy mill in the presence of steam. The products obtained have technological, physical and biopharmaco... | 11/17/1992 |
| 5164379 | Sucralfate/cyclodextrin complexes Complexes of sucralfate with alpha cyclodextrin, beta cyclodextrin, gamma cyclodextrin or 2-hydroxypropyl beta cyclodextrin are disclosed. Also disclosed are a process for producing complexes and compositions and a method for reducing gastric injury, empl... | 11/17/1992 |
| 5155219 | Process for producing cyclodextrin from raw starch by using attrition milling bioreactor A process for producing cyclodextrin from raw starch by mixing a culture supernatant of cyclodextrin gylcosyltransferase-producing microorganism as an enzyme source and a raw starch as a substrate, and stirring the mixture in the presence of an attrition ... | 10/13/1992 |
| 5142035 | Encapsulated palladium complexes and one part heat curable organopolysiloxane compositions Inclusion compounds of a cyclodextrin, such as ଲ-cyclodextrin, and a palladium halide-diene complex, such as a complex of PdCl2 and 1,5-cyclooctadiene have been found to be effective hydrosilylation catalysts. One part heat curable organo... | 08/25/1992 |
| 5134127 | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof Sulfoalkyl ether cyclodextrin derivatives and their use as solubilizing agents for water insoluble drugs for oral, intranasal, or parenteral administration are disclosed.... | 07/28/1992 |
| 5132298 | Diuresis by cyclodextrins and their derivatives A method for improvement in diuresis which comprises administering, to a subject in need of such improvement, a cyclodextrin or a derivative thereof in an amount effective to cause such improvement.... | 07/21/1992 |
| 5126333 | Pharmaceutical compositions having improved dissolution properties A pharmaceutical composition comprising a drug and a dehydrated cyclodextrin having improved dissolution properties, and the process for the preparation thereof.... | 06/30/1992 |
| 5120720 | Preparation of lipophile:hydroxypropylcyclodextrin complexes by a method using co-solubilizers The dissolution of lipophilic compounds in aqueous solutions of hydroxypropylcyclodextrins can be accelerated by the addition of co-solubilizers, such as ethanol or ammonia, which again can be removed, together with water, by evaporation or by freeze-dryi... | 06/09/1992 |
| 5104547 | Separating materials for chromatography comprising cyclodextrin chemically bonded to a support via a carbamic acid group The invention relates to a separating material for chromatography in which cyclodextrin is bonded to a support via a carbamic acid group.... | 04/14/1992 |
| 5098793 | Cyclodextrin films on solid substrates A large class of crosslinked cyclodextrin resins soluble in water to an extent under about 200 ppm but soluble in an organic solvent to an extent of at least 0.1 weight percent have good film-forming properties with a wide variety of solid phase substrate... | 03/24/1992 |
| 5096710 | Poison bait for control of noxious insects A bait composition in a tablet form, which comprises as the essential components (a) at least one insect-growth controlling agent chosen from (a-1) insect juvenile hormone-like compounds and (a-2) insect chitin-synthesis inhibitors, (b) dextrin and (c) a ... | 03/17/1992 |
| 5096894 | Rice dextrin oral rehydration solution An improved oral rehydration solution comprising a mixture of rice dextrin and required electrolytes is provided. The functionality of the rice dextrin in oral rehydration solutions is superior to glucose in infants with chronic diarrhea resulting in lowe... | 03/17/1992 |
| 5096893 | Regioselective substitutions in cyclodextrins A method for obtaining a desired pattern of substitution of hydroxyalkyl groups on cyclodextrins which comprises controlling the basicity of a reaction mixture comprising epoxide and cyclodextrins and a suitable solvent. Through the proper control of basi... | 03/17/1992 |
| 5089482 | Pharmaceutical compositions for nasal administration containing steroid hormones and dimethyl-ଲ-cyclodextrin Pharmaceutical compositions having a formulation and form suitable for nasal administration, and containing 17ଲ-estradiol and/or progesterone. According to the invention, the composition also contains dimethyl-ଲ-cyclodextrin.... | 02/18/1992 |
| 5079237 | Inclusion complex of nicardipine or its hydrochloride with beta-cyclodextrin and a sustained release pharmaceutical preparation containing the same There is described a new inclusion complex of nicardipine or its hydrochloride with beta-cyclohdextrin, which is prepared by admixing nicardipine or its hydrochloride with beta-cyclodextrin in a molar ratio of the compounds 1:0.9-1.1 under stirring at a t... | 01/07/1992 |
| 5075432 | Spherical cyclodextrin polymer beads The process entails forming a droplet of water, cyclodextrin and base in a non-polar solvent such as methylisobutylketone using polyvinyl butyral as an emulsifier. A cross-linking agent such as epichlorohydrin is reacted with the cyclodextrin and emulsify... | 12/24/1991 |
| 5071838 | Treatment of shock by cyclodextrins and their derivatives A method for treatment of shock which comprises administering, to a subject in need of such treatment, a cyclodextrin or a derivative thereof in an amount effective in such treatment.... | 12/10/1991 |
| 5070081 | Inclusion complexes of cyclodextrins by agglomeration A combined process is described in which inclusion complexes are formed from guest molecules and cyclodextrins during agglomeration of the cyclodextrins. Sufficient agitation in the presence of a small amount of water results in complex formation and bond... | 12/03/1991 |
| 5068226 | Pharmaceutical preparations containing cyclodextrins and their use in iontophoretic therapies Cyclodextrins and especially ionic cyclodextrin derivatives facilitate the iontophoretic delivery of pharmaceutically active agents.... | 11/26/1991 |
