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| Number | Title | Issue Date |
| 8093375 | Reactive polysaccharide derivatives, their preparation and their use A reactive polysaccharide derivative of formula, [Z1—B—SO2—CH2—CH2—O]n—PS—[OH]m (1), wherein 8 is a radical of formula (2a), (2b), (2c), (2d) or (2e), Z, is a rea... | 01/10/2012 |
| 8049003 | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof A particulate SAE-CD composition is provided. The SAE-CD composition has an advantageous combination of physical properties not found in known solid forms of SAE-CD. In particular, the SAE-CD composition possesses an advantageous physicochemical and morphological pr... | 11/01/2011 |
| 7834174 | Per-6-guanidino-, alkylamino-cyclodextrins, methods of their synthesis and their use for the compaction of DNA and intercellular delivery The invention relates to new compounds of type hexakis(6-deoxy-6-NH(CH2)n—R1)α-cyclodextrin and heptakis(6-deoxy-6-NH(CH2)n—R1)-(β-cyclodextrin, and octakis(6-deoxy-6-NH(CH2)n | 11/16/2010 |
| 7737269 | Process for preparing an alpha-lipoic acid/cyclodextrin complex and product prepared The invention relates to a process for the preparation of a cyclodextrin/alpha-lipoic acid complex, wherein in a first step, an alpha-lipoic acid and a cyclodextrin are dissolved in an aqueous alkaline solution having a pH above pH 7, and in a second step an acid is... | 06/15/2010 |
| 7632941 | Cyclodextrin derivatives, method for the preparation thereof and use thereof for the solubilization of pharmacologically active substances The invention relates to a cyclodextrin derivative corresponding to general formula (I) wherein n is a whole number from 1-6, m is a whole number equal to 5, 6 or 7, R1 is an OH group, all R1s are identical, Z is a thiourea group, X is a hydrog... | 12/15/2009 |
| 7595393 | Reduced malto-oligosaccharides Disclosed are a method for the reduction of an oligosaccharide mixture and an oligosaccharide mixture prepared thereby. In accordance with the disclosed invention, a mixture of oligosaccharides having a given DP profile is reduced to a DE of essentially zero by cata... | 09/29/2009 |
| 7459549 | Composition for preparing nanoporous material Disclosed herein is a composition for preparing a nanoporous material. The composition comprises i) a cyclodextrin derivative, ii) a thermostable matrix precursor, and iii) a solvent for dissolving the components i) and ii). The composition enables the preparation o... | 12/02/2008 |
| 7423027 | Methods of using gamma cyclodextrin to control blood glucose and insulin secretion Disclosed are methods of producing a blunted postprandial glycemic response in an individual, and/or reducing postprandial insulin secretion, said methods comprising administering to the individual a nutritional or other product comprising gamma-cyclodextrin. Also d... | 09/09/2008 |
| 7417109 | Polymers for delivering nitric oxide in vivo Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is prepared by reacting a polythiolated polymer with a nitro... | 08/26/2008 |
| 7405293 | Reduced malto-oligosaccharides Disclosed are a method for the reduction of an oligosaccharide mixture and an oligosaccharide mixture prepared thereby. In accordance with the disclosed invention, a mixture of oligosaccharides having a given DP profile is reduced to a DE of essentially zero by cata... | 07/29/2008 |
| 7316919 | Composite materials comprising supported porous gels This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked... | 01/08/2008 |
| 7307176 | Inclusion complex of taxol with 2-hydroxypropyl-beta-cyclodextrin The present invention relates to a method for producing a 2-hydroxypropyl-beta-cyclodextrin inclusion complex of taxol, said 2-hydroxypropyl-beta-cyclodextrin having a degree of substitution of 0.4 to about 0.9, wherein the method comprises admixing the 2-hydroxypro... | 12/11/2007 |
| 7291395 | Coated ion exchanged substrate and method of forming A method for making an ion exchange coating (e.g., a chromatographic medium) on a substrate comprising (a) reacting at least a first amine compound comprising amino groups, with at least a first polyfunctional compound, in the presence of a substrate to form a first... | 11/06/2007 |
| 7285157 | Air filter An air-filter for a circulating and/or recirculating air system using a filter medium containing a microbiologically effective amount of a polymeric biguanide or salt thereof. Also claimed is a method for reducing odors and/or air-borne micro-organisms in a circulat... | 10/23/2007 |
| 7276126 | Production of enzyme-resistant starch by extrusion A process for producing alpha-amylase resistant starch comprises extruding a feed starch at a temperature in the range of about 60-220° C., thereby producing a product alpha-amylase resistant starch. The feed starch can be in the form of an aqueous slurry or paste ... | 10/02/2007 |
| 7271259 | Solid phase host compositions A new family of silicon-based polymers has been prepared in which organic host components are bound covalently. The polymer is a polysilsesquioxane matrix comprising, for example, hosts such as cyclodextrins (CD) or calixarenes (CX). ... | 09/18/2007 |
| 7259153 | Drug formulation and delivery using crystalline methylated cyclodextrins The present invention is directed to pharmaceutical compositions containing crystalline methylated cyclodextrins, which enhance the solubility of the pharmaceutically active agent or agents of the formulation. ... | 08/21/2007 |
| 7211662 | Soluble highly branched glucose polymers and their method of production The invention relates to soluble highly branched glucose polymers having a reducing sugar content of less than 1%, characterized in that they have a level of α-1,6 glucoside bonds greater than 10%, preferably of between 12 and 30%, a Mw value of between 0.35×10 | 05/01/2007 |
| 7208086 | Saccharide and support for chromatography A novel conjugate of a support material and an oligomer or polymer of a saccharide that is linked to the support material via urea linkages, and in which the oligomers or polymers are cross-linked via urea linkages provides a valuable stationary phase for chromatogr... | 04/24/2007 |
| 7202233 | Alprazolam inclusion complexes and pharmaceutical compositions thereof A pharmaceutical composition an inclusion complex and methods for treating patients and preparing said complex disclosed for transmucosal delivery comprising an inclusion complex of (a) alprazolam and (b) a water soluble 2-hydroxypropyl-beta-cyclodextrin, and a phar... | 04/10/2007 |
| 7201844 | Composite matrices with interstital polymer networks The present invention relates in general to the preparation and use of matrices having solid spaces, interstitial spaces and interstitial polymer networks. In particular, the interstitial polymer networks have utility in chemical and biochemical separations, solid p... | 04/10/2007 |
| 7202231 | β-Cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases Methods of reducing the risk of transmission of a sexually transmitted pathogen by contacting the pathogen or cells susceptible to infection by the pathogen with a β-cyclodextrin are provided. Methods for reducing the risk of transmission of a sexually transmitted ... | 04/10/2007 |
| 7189288 | Enzyme-resistant starch and method for its production A process for producing an enzyme-resistant starch uses an aqueous feed composition that comprises (i) starch that contains at least about 50% by weight amylose, (ii) water, and (iii) alcohol. The concentration of starch in the feed composition is between about 5% a... | 03/13/2007 |
| 7186702 | Method of treating using methyl-beta-cyclodextrin The present invention relates to a composition useful for the treatment of leishmaniasis said composition comprising pharmaceutically effective amount of methyl-beta-cyclodextrin, optionally along with other anti-leishmanial agent(s) and/or pharmaceutically a... | 03/06/2007 |
| 7186433 | Fibre-enriched drinks The subject of the invention is a fiber-enriched low-calorie drink, characterized in that it comprises 1.5 to 90 g, by dry weight per liter of drink, or branched maltodextrins having between 15 and 35% of 1→6 glucoside linkages, a reducing sugar content of less th... | 03/06/2007 |
| 7182941 | Method for reducing malodor impression on inanimate surfaces comprising uncomplexed cyclodextrin Methods of treating an inanimate object or inanimate surface which has malodor impression to reduce the malodor impression comprise the step of contacting the inanimate object or inanimate surface with an effective amount of a composition for reducing malodor impres... | 02/27/2007 |
| 7182972 | Water-soluble bean-based extracts This invention relates to a water-soluble bean-based extract including one or more isoflavone glycosides. Also INCLUDED is a method of preparing such a water-soluble bean-based extract. ... | 02/27/2007 |
| 7176221 | Low dose pharmaceutical composition having uniform drug distribution and potency A method for manufacturing a pharmaceutical composition having uniform drug distribution and potency is described which utilizes silicon dioxide to reduce the loss of active ingredient during the manufacturing process. The method is particularly useful for the manuf... | 02/13/2007 |
| 7166226 | Ion exchange cryptands covalently bound to substrates One embodiment of the invention comprises an ion exchange composition formed by reacting unsaturated carbon to carbon moieties pendant from derivatized ion binding cryptands with a support substrate under free radical activation conditions to form a covalent bond th... | 01/23/2007 |
| 7163931 | Compositions of estrogen-cyclodextrin complexes Pharmaceutical compositions comprising low doses of sensitive complexes between an estrogen and a cyclodextrin are provided with improved stability. In specific embodiments the composition comprises a complex between ethinyl estradiol and β-cyclodextrin in a granul... | 01/16/2007 |
| 7157446 | Complex of ras-farnesyltransferase inhibitor, a cyclodextrin, and ethanol A ras-farnesyltransferase inhibitor complex formed from a ras-farnesyltransferase inhibitor or a pharmaceutically acceptable salt thereof, a substituted cyclodextrin, and ethanol is provided. The complex has unexpectedly high aqueous solubility of the ras-farnesyltr... | 01/02/2007 |
| 7153354 | Chemically modified plasticized starch compositions by extrusion processing A chemically modified plasticized starch (CMPS) is prepared by reacting starch with an organic dibasic acid or an anhydride of the acid in the presence of a plasticizer using optional free radical initiators, and optionally with the incorporation of nano clays in th... | 12/26/2006 |
| 7151121 | Polyurethane containing a polyol composition comprising a highly branched polysaccharide, mix and process for preparation thereof The invention relates to a polyurethane obtainable by reacting a polyisocyanate and a polyol composition comprising a highly branched polysaccharide of randomly bonded glucopyranose units or an alkoxylated derivative of the same. The polysaccharide has an average nu... | 12/19/2006 |
| 7138154 | Process for preparing a low-calorie food The subject of the invention is a process for preparing a food product with reduced calorific value, comprising the step consisting in replacing all or part of the high-calorie substances of the food with an effective quantity, in terms of the reduction of the calor... | 11/21/2006 |
| 7115586 | Non-inclusion cyclodextrin complexes The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization of the active ingredient is enhanced by combining it with β-cyclode... | 10/03/2006 |
| 7115297 | Nutritionally fortified liquid composition with added value delivery systems/elements/additives A shelf-stable, ready to use, water-like composition for humans/animals; as an adjunct to fiber-water, and/or safe drinking water, consumed directly, tube feedings, or in the preparation/reconstitution of food(s)/beverage(s). Fortified Fiber-Water is fiber-water, wi... | 10/03/2006 |
| 7109324 | Process for chemically bonding an odor-encapsulating agent to textiles and textiles formed by the process A process for chemically bonding an odor-encapsulating agent to textiles includes reacting a cyclodextrin with a cross-linking agent capable of forming ether bonds with the cyclodextrin and with the textile material, and curing the textile material treated with a mi... | 09/19/2006 |
| 7109354 | Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I | 09/19/2006 |
| 7105500 | Process for the antimicrobial treatment of fiber materials A process for the antimicrobial treatment of fiber materials, comprising applying to the fiber material an inclusion complex of a fiber-reactive cyclodextrin derivative with an antimicrobial agent selected from the group consisting of (a) halogeno-o-hydroxydiphenyl ... | 09/12/2006 |
| 7101702 | Fermentative preparation process for and crystal forms of cytostatics The invention relates to a new process for concentrating epothilones in culture media, a new process for the production of epothilones, a new process for separating epothilones A and B and a new strain obtained by mutagenesis for the production of epothilones, as we... | 09/05/2006 |
