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| Number | Title | Issue Date |
| 5804563 | Synthetic receptors, libraries and uses thereof The invention is directed to synthetic receptor(s) which comprises a polyfunctional organic template covalently linked to two or more oligomers which may independently be the same or different and may independently be straight chain or branched. The templ... | 09/08/1998 |
| 5798343 | 7-O-Carbamoylheptose derivatives, process for their production and their use in treating pseudomonas infections The invention describes 7-O-carbamoyl heptose derivatives of general formula (I) in which R is the substituent R1 or a group of general formula (II) in which R1 is a hydrogen atom, a methyl group or a suitable linker substituent suit... | 08/25/1998 |
| 5795749 | Use of 2-deoxyribose-5-phosphate aldolase to prepare 2-deoxyfucose, analogues and derivatives Processes using 2-deoxyribose-5-phosphate aldolase (DERA) are described for the preparation of 2-deoxyfucose and related compounds. In one embodiment, DERA is used to catalyze the condensation of acetaldehyde as donor and a 2(R)-hydroxy-3-(hydroxy or merc... | 08/18/1998 |
| 5792839 | Catalytic method of forming a glycosidic linkage The invention relates to methods that permit the rapid construction of oligosaccharides and other glycoconjugates. Methods for forming multiple glycosidic linkages in solution in a single step are disclosed. The invention takes advantage of the discovery ... | 08/11/1998 |
| 5792840 | Lipid A analogs having immunoactivating and anti-tumor activity Compounds of formula (I): ##STR1## in which: R1 is hydroxy, protected hydroxy, fluorine, or --OP(O)(OH)2 ; R2 and R3 are independently optionally substituted C6 -C20 aliphatic acyl; R | 08/11/1998 |
| 5789572 | Method for the preparation of 1,4,-anhydro-2-deoxy-d-erythropentitol Proposed is a novel synthetic route for the preparation of 1,4-anhydro-2-deoxy-D-erythropentitol, which is a useful material in the synthesis of antibiotics, starting from 2-deoxy-D-ribose via 2-deoxy-D-erythropentitol as an intermediate. 2-Deoxy-D-erythr... | 08/04/1998 |
| 5786469 | 1-C-perflouroalkyl glycosides, preparation process and uses thereof The invention relates to 1-C-perfluoroalkyl glucosides consisting essentially of a monosaccharide having an anomeric carbon directly linked to a perfluoroalkyl radical and a hydroxyl group. These glycosides are prepared by a process comprising: (a) reacti... | 07/28/1998 |
| 5786167 | Method and culture medium for identification of salmonellae The invention comprises a culture medium and method for distinguishing bacteria of Salmonella species from other gram-negative bacteria, especially those belonging to the family Enterobacteriaceae. It is based on the ability of salmonellae to utilize meli... | 07/28/1998 |
| 5785975 | Adjuvant compositions and vaccine formulations comprising same The present invention relates to phospholipid-polysaccharide adjuvant compositions and to vaccine formulations comprising same, as well as to methods of making and using such adjuvants and vaccines.... | 07/28/1998 |
| 5783408 | Method for screening potential anti-obesity agents A method for screening a compound as a potential anti-obesity agent by determining whether the compound stimulates micro motion of cells in vitro is described... | 07/21/1998 |
| 5782982 | Method of removing silica or silicates from solids resulting from the strong acid hydrolysis of cellulosic and hemicellulosic materials A method of removing silica or silicates from solids results from the acid hydrolysis of materials containing cellulose and hemicellulose is disclosed. The method includes the steps of treating the solids with a metal hydroxide solution to produce an extr... | 07/21/1998 |
| 5783677 | Deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds The present invention relates to a method for making a compound of the structure: ##STR1## comprising the steps: (a) adding 6-deoxy--L-mannopyranosyl bromide, 2,3,4-tri-O-benzoate; DMSO; a base, selected from the group including tertiary ... | 07/21/1998 |
| 5773606 | Catalyst regeneration The present invention relates to the regeneration of a supported molybdenum catalyst which has been used for the epimerisation of a saccharide. The preferred epimerisation is the conversion of glucose to mannose. The catalyst is regenerated by using an ox... | 06/30/1998 |
| 5763157 | Biological reagent spheres A reagent sphere is disclosed comprising at least one biological reagent and a glass-forming filler material in a concentration sufficient to facilitate formation of a glassy, porous composition, wherein the reagent semi-sphere is water soluble and has a ... | 06/09/1998 |
| 5759993 | Modified sialyl Lewisx compounds The present invention is drawn to methods for the synthesis of sialyl Lewisx derivatives modified at the C-2 and/or C-6 position of GlcNAc employing chemo-enzymatic synthesis. The derivatives find use in the treatment and prevention of diseases... | 06/02/1998 |
| 5759764 | Cryopreservation solution A simple, inexpensive, physiologically compatible, cryopreservation solution which includes the innocuous components of (i) glycerol, (ii) an alkali metal chloride salt, (iii) a monosaccharide, and (iv) serum albumin.... | 06/02/1998 |
| 5759825 | Method for synthesizing 2-ketoaldonic acids 2-Ketoaldonic acid is synthesized by aldolase condensation reaction involving pyruvate and an aldose acceptor in the presence of excess pyruvate. After the reaction is substantially complete, the excess pyruvate is removed from the reaction mixture by tre... | 06/02/1998 |
| 5756072 | Alkylpolyglycosides with a high degree of a polymerization and a process for the preparation thereof The present invention relates to a process for preparing alkylpolyglycoside compositions. Specifically the process is a direct synthesis producing compositions of highly polymerized alkylpolyglycosides in high yield. The invention further relates to alkyl... | 05/26/1998 |
| 5756069 | Amphipathic polychelating compounds and method of use An amphipathic polychelating compound including a hydrophilic polymeric moiety having a main backbone and a plurality of reactive side groups, a lipid-soluble anchor linked to the N terminal of the polymeric moiety, and a plurality of chelating agents lin... | 05/26/1998 |
| 5750679 | Process for obtaining pharmacologically active compounds from complex mixtures of substances A process for obtaining pharmacologically active compounds from complex mixtures of substances Free organic acids, hydroxy acids, fatty alcohols, sugars and hydroxy-substituted steroids are obtained from complex mixtures of substances by mixing the materi... | 05/12/1998 |
| 5747347 | Labelled carbohydrates and their use in assays A method for distinguishing between carbohydrates or glycoconjugates in a mixture thereof, wherein the or each carbohydrate or glycoconjugate is a hydrophilic fluorescently-labelled saccharide molecule, wherein the label is a --NR--Ph--CO-- group, wherein... | 05/05/1998 |
| 5739303 | Method for decarbonylation of sugars The present invention discloses a method for direct decarbonylation of sugars. The method is based on the conversion of the sugars in the presence of a phosphine metal complex. These complexes are added in catalytic amounts if at the same time urea or an ... | 04/14/1998 |
| 5739302 | Manufacture and use of novel glycosides of catechol estrogens There are described novel glycosides of catechol estrogen, a method of preparing the same, and a medicament comprising one of the glycosides as an active ingredient. The glycosides are shown by the formula of ##STR1## wherein X is carbonyl group or ... | 04/14/1998 |
| 5733893 | Method of identifying molecules that regulate FGF activity Disclosed are fibroblast growth factor (FGF) binding and FGF receptor activation, and a method of identifying small molecular weight compounds that interact with FGF to modulate its activity such as, e.g., activators and inhibitors. Illustrative small oli... | 03/31/1998 |
| 5734045 | Glycogen polysaccharides Glycogen polysaccharides substantially free of nitrogenous compounds and reducing sugars.... | 03/31/1998 |
| 5728225 | Viscous liquid compositions of xylitol and a process for preparing them The invention relates to viscous liquid compositions of xylitol which are noncrystallizable or which exhibit retarded crystallization, characterized by the fact that they contain: from 51% to 80% of xylitol, from 0.1% to 44% of D-arabitol, from 5% to 48.9% of ... | 03/17/1998 |
| 5726046 | Method of producing sugars using strong acid hydrolysis A economically viable method for producing sugars using concentrated acid hydrolysis of biomass containing cellulose and hemicellulose is disclosed. The cellulose and hemicellulose in the biomass is first decrystallized and then hydrolyzed to produce a hy... | 03/10/1998 |
| 5726031 | Test media and quantitative method for identification and differentiation of biological materials in a test sample A test method and medium for quantitatively identifying and distinguishing biological materials in a test sample. A first biological material has enzyme specificity for a first chromogenic substrate, a second biological material has enzyme specificity for... | 03/10/1998 |
| 5723589 | Carbohydrate conjugated bio-active compounds Methods and compositions are provided which increase the cellular uptake of bioactive materials by covalently bonding such compounds to carbohydrate moieties through chemical linkers using other than glycosidic bonds. Numerous carbohydrates, linkers and b... | 03/03/1998 |
| 5720935 | Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides from stannyl precursors A method of making a radiolabeled pyrimidine nucleoside or nucleotide is described. In the method, a stannylated pyrimidine nucleoside or nucleotide is contacted in an aqueous solution with a radioactive iodide, bromide, chlorine or astatine ion in the pr... | 02/24/1998 |
| 5719020 | 4,7-dialkoxy N-acetylneuraminic acid derivatives and methods for detection of influenza type A and B viruses in clinical specimens Chromogenic and fluorogenic 4,7-dialkoxy-N-acetylneuraminic acid substrates of the general formula ##STR1## are provided wherein R1 and R2 are alkyl groups containing 1 to 4 carbon atoms and R3 is a chromogenic or flu... | 02/17/1998 |
| 5714360 | Photoactivatable water soluble cross-linking agents containing an onium group A chemical linking agent is formed of a di- or higher functional photoactivatable compound having at least one group that is charged under the conditions of use in order to provide improved water solubility. The linking agent contains two or more photorea... | 02/03/1998 |
| 5712107 | Substitutes for modified starch and latexes in paper manufacture The present invention provides methods of making paper utilizing glucans, produced by the glucosyltransferase C enzyme of the species Streptococcus mutans, instead of modified starches. The present glucans are functionally similar to the hydroxethyl modif... | 01/27/1998 |
| 5708162 | Process for the preparation of low molecular weight polysaccharide ethers Process for the preparation of low molecular weight polysaccharide ethers which can be employed in binders for improving adhesive power and film-forming properties, by oxidative degradation of relatively high molecular weight polysaccharide ethers, which ... | 01/13/1998 |
| 5705369 | Prehydrolysis of lignocellulose The invention relates to the prehydrolysis of lignocellulose by passing an acidic or alkaline solution through solid lignocellulosic particles with removal of soluble components as they are formed. The technique permits a less severe combination of pH, te... | 01/06/1998 |
| 5703224 | Antiviral c-nucleoside derivatives The present invention is composed of a nucleoside derivative of the following general formula I!: ##STR1## (wherein B represents adenin-9-ylmethyl, guanin-9-ylmethyl, hypoxanthin-9-ylmethyl, thymin-1-ylmethyl, uracil-1-ylmethyl, or cytosin-1-y... | 12/30/1997 |
| 5700916 | Solution and solid-phase formation of glycosidic linkages The invention relates to methods that permit the rapid construction of oligosaccharides and other glycoconjugates. Methods for forming multiple glycosidic linkages in solution in a single step are disclosed. The invention takes advantage of the discovery ... | 12/23/1997 |
| 5688922 | Substituted fucopyranosides 2-Chloromethyl-3-(tri-O-benzyl--L-C-fucopyranoside)-1-propene and methods of making the same are described. Methods of combining this substituted fucopyranose with triterpenoid acid also are described.... | 11/18/1997 |
| 5686603 | Sulfated polyhydroxy compounds as anionic surfactants and a process for their manufacture The present invention relates to sulfated polyhydroxy compounds used as anionic surfactants and to processes for their manufacture.... | 11/11/1997 |
| 5681927 | Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy Chelated radionuclide compositions are provided for conjugation to polypeptides and carbohydrates. The resulting conjugates may be used in diagnosis and therapy.... | 10/28/1997 |
