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Apparatus for Simulating a High Five
A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."
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| Number | Title | Issue Date |
| 7423131 | Busulfan immunoassay Novel conjugates of busulfan and novel busulfan immunogens derived from α-substituted derivatives of busulfan and antibodies generated by these busulfan linked immunogens are useful in immunoassays for the quantification and monitoring of busulfan in biological flu... | 09/09/2008 |
| 7408044 | Carrier protein having an adjuvant effect The invention relates to an adjuvant product which is intended to improve the activity of a molecule when administered to a host, characterized in that it comprises at least one part of the P40 protein of Klebsiella pneumoniae or a protein having at least 80% homolo... | 08/05/2008 |
| 7371829 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites The invention provides haptens, immunogens comprising such haptens coupled to an antigenicity-conferring carrier material, conjugates comprising such haptens bonded to a labelling agent as well as, antibodies raised against such immunogens and capable of binding wit... | 05/13/2008 |
| 7282339 | Competitive immunoassay The present invention provides ligand-detection reagents, ligand analogs and methods for determining the presence of a ligand in a sample. The ligand-detection reagent comprises a ligand-binding antibody and a ligand analog to form an antibody-ligand analog complex ... | 10/16/2007 |
| 7238791 | 6-monoacetylmorphine derivatives useful in immunoassay Analogs of 6-monoacetyl morphine (6-MAM) are described. These include analogs derivatized at either the C-3 position, the C-6 position, or the nor position of the molecule. These analogs allow for elaboration with linkers terminated by a functional group such as an ... | 07/03/2007 |
| 7235370 | Site-specific aminoglycoside derivatives for use in immunodiagnostic assays A method of making a derivatized aminoglycoside includes reacting an aminoglycoside with at least 2 equivalents of a divalent metal ion in an aprotic solvent to complex two neighboring amino group and hydroxyl group pairs; reacting the non-complexed amino groups wit... | 06/26/2007 |
| 7223553 | Immunoassays for everolimus Immunoassays for the detection of everolimus are provided. Compounds for producing antibodies for everolimus, as well as antibodies produced therefrom, are also provided. ... | 05/29/2007 |
| 7217802 | Method and kit for detecting, or determining, 3,4-methylenedioxymethamphetamine The invention provides a hapten, an immunogen comprising the hapten coupled to an antigenicity-conferring carrier material, a conjugate comprising the hapten coupled to a labelling agent, as well as, antibodies raised against the aforementioned immunogen and capable... | 05/15/2007 |
| 7217530 | Process for detecting PrP using a macrocyclic adjuvant ligand A process for detecting the forms of the prion pathogens responsible for subacute, transmissible, spongiform encephalopathies, including a macrocyclic adjuvant ligand (AML), free or bound to a support, that is added to a biological sample capable of containing PrP | 05/15/2007 |
| 7189582 | Compositions and methods for detection of sirolimus Compounds are disclosed comprising a moiety, such as a poly(amino acid), a non-poly(amino acid) label moiety, or a non-poly(amino acid) immunogenic carrier, linked to a sirolimus compound at position 26 or at position 32. Such sirolimus compounds comprising an immun... | 03/13/2007 |
| 7118757 | Meningococcal class 1 outer-membrane protein vaccine Outer-membrane vesicles, Class 1 outer membrane proteins of Neisseria meningitidis, fragments or oligopeptides containing epitopes of the Class I OMP can be used to immunize against meningococcal disease. ... | 10/10/2006 |
| 7105643 | Monoclonal antibodies specific for crack cocaine metabolites, a cell line producing the same, and crack cocaine conjugates A monoclonal antibody, and a cell line capable of producing the same, has been produced with the ability to detect the primary metabolites generated from the pyrolysis of smokeable, or “crack”, cocaine. This monoclonal antibody, while being highly specific for a... | 09/12/2006 |
| 7074416 | Antigen of hybrid M protein and carrier for group A streptococcal vaccine Recombinant hybrid streptococcal M protein antigens are provided which elicit protective antibodies against Group A streptococci and prevent rheumatic fever. Recombinant hybrid genes which encode the antigen are provided. Vaccine compositions and methods of administ... | 07/11/2006 |
| 7018637 | Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines Multivalent immunogenic molecules comprise a carrier molecule containing at least one functional T-cell epitope and multiple different carbohydrate fragments each linker to the carrier molecule and each containing at least one functional B-cell epitope. The carrier ... | 03/28/2006 |
| 7019111 | Glycosylated ligand/receptor specificity exchangers specific for bacterial adhesion receptors The present invention generally relates to compositions and methods for preventing and treating human diseases including, but not limited to, pathogens such as bacteria, yeast, parasites, fungus, viruses, and cancer. More specifically, embodiments described herein c... | 03/28/2006 |
| 7014857 | Anti-sepsis conjugate vaccine The present invention provides an immunogenic conjugate comprising biologically deacylated gram-negative bacterial moieties linked to D. discoideum proteinase 1, as well as novel subunits thereof, and methods of making and using the conjugates in vaccines to ... | 03/21/2006 |
| 6964769 | Molecular antigen array The invention provides compositions and processes for the production of ordered and repetitive antigen or antigenic determinant arrays. The compositions of the invention are useful for the production of vaccines for the prevention of infectious diseases, the treatme... | 11/15/2005 |
| 6960457 | Reversible immobilization of arginine-tagged moieties on a silicate surface This invention provides materials and methods for the site specific attachment of virtually any moiety to a layered silicate surface. The methods involve covalently attaching the moiety to an arginine tag; and contacting the arginine tag with the layered silicate (e... | 11/01/2005 |
| 6927035 | Antiuracil monoclonal antibody A monoclonal antibody which reacts strongly with uracil and thymine but scarcely with N-carbamyl-β-alanine; a hybridoma producing this monoclonal antibody; a method of immunochemically assaying uracil or thymine characterized by using the above-described monoclonal... | 08/09/2005 |
| 6869606 | Biotinylated-chemokine antibody complexes Biotinylated pharmacologically active agents and complexes containing same are disclosed. In particular, biotinylated-chemokines are described. The complexes further include an anti-biotin antibody that selectively binds to biotin. The complex can be dissociated by ... | 03/22/2005 |
| 6855321 | Polyepitope carrier protein The invention relates to polyepitope carrier proteins that comprise at least five CD4+ T cell epitopes, for conjugation to capsular polysaccharides. The carrier proteins are use useful as components of vaccines that can elicit a T-cell dependent immune response. The... | 02/15/2005 |
| 6780420 | Carrier protein having an adjuvant effect, immunogenic complex containing it, process for their preparation, nucleotide sequence and vaccine The invention relates to an adjuvant product which is intended to improve the activity of a molecule when administered to a host, characterized in that it comprises at least one part of the P40 protein of Klebsiella pneumoniae or a protein having at least 80%... | 08/24/2004 |
| 6780978 | Fluorescence-activating antisera and IgG fraction therefrom This invention allows the fluorescence analysis of a nonfluorescent dye with high specificity and high sensitivity by virtue of the formation of a complex among an antibody directed against an immunogen having the nonfluorescent dye, an antiserum containing the anti... | 08/24/2004 |
| 6716410 | Reagents and methods for diagnosing, imaging and treating atherosclerotic disease The invention provides a novel human Mab Fab, cloned by phage display, and its use in diagnostic and therapeutic methods. In particular the invention provides a method for analyzing the OxLDL components of atherosclerotic plaques in vivo and a means to determine the... | 04/06/2004 |
| 6670196 | Rapid evaluation of the ratio of biological molecules The invention relates in part to novel methods of rapidly determining the ratio of biological molecules. The invention also relates in part to a kit for rapidly determining the ratio of biological molecules.... | 12/30/2003 |
| 6660842 | Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen The present invention generally relates to compositions and methods for preventing and treating human diseases including, but not limited to, pathogens such as bacteria, yeast, parasites, fungus, viruses, and cancer. More specifically, embodiments describ... | 12/09/2003 |
| 6656472 | Multi oligosaccharide glycoconjugate bacterial meningitis vaccines Multivalent immunogenic molecules comprise a carrier molecule containing at least one functional T-cell epitope and multiple different carbonhydrate fragments each linked to the carrier molecule and each containing at least one functional B-cell epitope. ... | 12/02/2003 |
| 6656694 | Method for identifying a ligand for a biological substrate A method of identifying a ligand for a second binding site (5) on a biological substrate (1) is disclosed. The method comprises determining the effect of a candidate compound (9) on the binding of a probe compound (2) which binds to a first binding site (... | 12/02/2003 |
| 6642354 | Molecular mimetics of unique Neisseria meningitidis serogroup B epitopes Novel bactericidal antibodies against Neisseria meningitidis serogroup B ("MenB") are disclosed. The antibodies either do not cross-react or minimally cross-react with host tissue polysialic acid and hence pose minimal risk of autoimmune activity. The ant... | 11/04/2003 |
| 6613739 | Deuterated cyclosporine analogs and their use as immunomodulating agents Cyclosporine derivatives are disclosed which possess enhanced efficacy and reduced toxicity over naturally occurring and other presently known cyclosporins and cyclosporine derivatives. The cyclosporine derivatives of the present invention are produced by... | 09/02/2003 |
| 6593137 | Antibodies specific for fullerenes This invention provides a hybridoma produced by the fusion of a mouse antibody-producing cell and a mouse myeloma which is designated 1-10F-8A and deposited with the ATCC under Accession Number PTA-279, said hybridoma producing a monoclonal antibody which... | 07/15/2003 |
| 6548645 | Immunoassay for 2-oxo-3-hydroxy LSD To improve the detection of LSD, and LSD metabolites in biological samples, antibodies are raised to 2-oxo-3-hydroxy-LSD conjugated to a protein carrier. Selected antibodies are matched with an immunoassay reagent in which the 2-oxo-3-hydroxy-LSD is conju... | 04/15/2003 |
| 6541007 | Vaccine for Pseudomonas aeruginosa A C-terminal pilin peptide vaccine for immunizing or treating a patient for infection by a Pseudomonas aeruginosa (PA) infection is disclosed. The peptide comprises the peptide identified as SEQ ID NOS. 3-6; and a carrier protein conjugated to the peptide... | 04/01/2003 |
| 6489131 | Interference reduction by rheumatoid factors The invention concerns a method for the determination of an analyte in which rheumatoid factors or rheumatoid-factor-like substances are added as an interference reducing reagent to reduce of avoid a hook effect. The invention in addition concerns suitabl... | 12/03/2002 |
| 6482648 | Stable troponin preparation and the use thereof as a calibrator/control in immunoassays The present invention relates to methods for the production of a stable troponin preparation and its use as a calibrator and/or control in immunoassays. The formulation is prepared from mammalian, preferably bovine, heart tissue which provides a calibrato... | 11/19/2002 |
| 6476199 | Reagents for lysergic acid diethylamide immunoassay The present invention provides hapten derivatives that are useful for the preparation of antigens, antibodies and reagents having superior performance characteristics for use in immunoassays for the detection of LSD and nor-LSD. In the present invention t... | 11/05/2002 |
| 6458923 | Modified position (7) bradykinin antagonist peptides The substitution of the L-Pro at the 7-position of the peptide hormone bradykinin or other substituted analogs of bradykinin with an isoquinoline derivative which converts bradykinin agonists into bradykinin antagonists. The invention further includes the... | 10/01/2002 |
| 6451766 | Neuraminic acid derivatives, their preparation and their medical use Compounds of formula (I) or their salts or esters: ##STR1## [wherein R1 is alkyl or haloalkyl; R2 and R3 each represents hydrogen or aliphatic acyl; X is hydroxy, halogen, alkoxy, or a group of formula Ra O--, w... | 09/17/2002 |
| 6437099 | Fluorescene--activating antisera and IgG fraction therefrom An antiserum containing an antibody, which when combined with an immunogen having a nonfluorescent dye, confers fluorescent ability to the dye. In particular, an antiserum which confers fluorescent ability on a conjugate of an immunogenic substance and Ma... | 08/20/2002 |
| 6410696 | Cyclosporin immunoassay A method of measuring the amount of cyclosporin in a sample suspected of containing cyclosporin is disclosed. A method of inactivating interfering cross-reactive material in an assay for measuring the amount of cyclosporin in a sample suspected of contain... | 06/25/2002 |