Pizza Pie With Concentric Rings of Crust
A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.
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| Number | Title | Issue Date |
| 7985732 | Unitary combination of FSH and hCG A novel ovulatory induction paradigm entails administration of hCG in combination with FSH during all stages of treatment, where the ratio of FSH to hCG is adjusted to optimize ovulatory stimulation and minimize complications. The use of compositions characterized b... | 07/26/2011 |
| 7964562 | Unitary combinations of FSH and hCG A novel ovulatory induction paradigm entails administration of hCG in combination with FSH during all stages of treatment, where the ratio of FSH to hCG is adjusted to optimize ovulatory stimulation and minimize complications. The use of compositions characterized b... | 06/21/2011 |
| 7910709 | β-like glycoprotein hormone polypeptide and heterodimer Novel β10 polypeptides and heterodimers thereof, and nucleic acid molecules encoding the same are disclosed. The invention also provides vectors, host cells, selective binding agents, and methods for producing β10 polypeptides and heterodimeric forms thereof, spec... | 03/22/2011 |
| 7687610 | Human chorionic gonadotropin superagonists The invention is directed toward a human glycoprotein hormone having at least one, two, three, four, or five basic amino acids in the α-subunit at positions selected from the group consisting of positions 11, 13, 14, 16, 17, and 20. The invention is also directed t... | 03/30/2010 |
| 7442376 | Glycoprotein hormone compositions containing two β subunits Forms of differentially acting glycoprotein hormones are disclosed. These compositions are of the formula β1-(linker1)m-α-(linker2)n-β2; (1) β1-(linker1 | 10/28/2008 |
| 7405197 | Use of hCG in controlled ovarian hyperstimulation The invention provides a protocol leading to improved embryo implantation rates and/or decreased miscarriage rates in which hCG, or a bio-analogue, is administered during the follicular phase. ... | 07/29/2008 |
| 7361349 | Peptide, immunogenic composition and vaccine or medical preparation, a method to immunize animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine A peptide that comprises a modified tandem GnRH decapeptide sequence which allows for a testosterone level that is essentially nondetectable after vaccination with the peptide in a suitable dosage and/or allows for an immunogenic response that allows for the effecti... | 04/22/2008 |
| 7358341 | Beta-like glycoprotein hormone polypeptide and heterodimer Novel β10 polypeptides and heterodimers thereof, and nucleic acid molecules encoding the same are disclosed. The invention also provides vectors, host cells, selective binding agents, and methods for producing β10 polypeptides and heterodimeric forms thereof, spec... | 04/15/2008 |
| 7317095 | Mutant glycoproteins The inventors have designed novel FSH mutants with increased glycosylation and longer half-lives for use in inducing folliculogenesis in human patients. The use of a FSH mutant preparation of the invention permits the use of lower cumulative doses of FSH to achieve ... | 01/08/2008 |
| 7291339 | Homogeneity and secretion of a recombinant follicle stimulating hormone (FSH) in mammalian systems A hybrid protein includes two coexpressed amino acid sequences forming a dimer. Each sequence contains the binding portion of a receptor, such as TBP1 or TBP2, or a ligand, such as IL-6, IFN-β and TPO, linked to α subunit of a natural heterodimeric scaffold. Each ... | 11/06/2007 |
| 7282352 | Homogeneity and secretion of recombinant proteins in mammalian systems The present invention relates to a method for improving homogeneity and/or secretion of a recombinant protein of interest expressed in mammalian cells by replacing the endogenous signal peptide sequence of the DNA encoding the protein of interest with that of human ... | 10/16/2007 |
| 7202215 | Long-acting follicle stimulating hormone analogues and uses thereof This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject. ... | 04/10/2007 |
| 7173113 | Long-acting hormone and growth factor compositions and uses thereof This invention provides VEGF-FSH compounds having increased serum half-lives relative to either native VEGF or FSH, in which both VEGF and FSH are biologically active. This invention also provides related compositions and methods for increasing fertility, egg produc... | 02/06/2007 |
| 7112341 | Pulmonary administration of dry powder formulations for treating infertility Provided are stabilized follicle stimulating protein (FSP) dry powder compositions for aerosolized delivery to the deep lung, methods of preparing and administering such compositions, and methods for treating infertility involving administering the dry powders by pu... | 09/26/2006 |
| 7109171 | Methods for treating FSH related conditions with GnRH antagonists Methods for treating FSH related conditions, such as prostatic intraepithelial neoplasia, pedophilia, infertility, or vaginal bleeding, with GnRH antagonists are disclosed. The methods of the invention generally feature administering to a subject a GnRH antagonist s... | 09/19/2006 |
| 7081446 | Long-acting follicle stimulating hormone analogues and uses thereof This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject. ... | 07/25/2006 |
| 7070788 | Follicle stimulating hormone superagonists The invention is directed toward a human glycoprotein hormone having at least one, two, three, four, or five basic amino acids in the α-subunit at positions selected from the group consisting of positions 11, 13, 14, 16, 17, and 20. The inventions is also directed ... | 07/04/2006 |
| 7022822 | Highly purified gonadotropin compositions and process for preparing them Purification process of humanPurification process of human urinary gonadotropins of high biological activity and chemical purity absolutely free of foreign contaminating materials derived from the use of biological reagents or chromatography dyes, from crude of gona... | 04/04/2006 |
| 6987172 | Multifunctional single chain glycoprotein hormones comprising three or more β subunits Glycosylated or nonglycosylated molecules of the formula β1-(linker1)n1-β2-(linker2)n2-β3-(linker3)n | 01/17/2006 |
| 6977242 | Two gonadotropin releasing hormones and a method to isolate the same The present invention relates to two novel Gonadotropin releasing hormones muGnRH I and muGnRH II of amino acid SEQ ID 1 as QHWSAWRLPG, and SEQ ID 2 QHWSWGILPG respectively, useful for induced breeding in fish both in combination and alone, by activating production ... | 12/20/2005 |
| 6911206 | Fusion proteins comprising carriers that can induce a dual immune response The subject invention provides a fusion protein for producing a dual immune response in a vertebrate, which fusion protein comprises: (a) a first proteinaceous portion analogous to all or part of a peptide endogenously synthesized within the vertebrate, the activity... | 06/28/2005 |
| 6828415 | Oligopeptide lyophilisate, their preparation and use A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% v/v, the solution is transferred to water and freeze dried. ... | 12/07/2004 |
| 6761890 | Peptide, immunogenic composition and vaccine or medical preparation, a method to immunize animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine A peptide that comprises a modified tandem GnRH decapeptide sequence which allows for a testosterone level that is essentially non-detectable after vaccination with the peptide in a suitable dosage and/or allows for a an immunogenic response that allows for the effe... | 07/13/2004 |
| 6716428 | Antigenic modification of polypeptides Endogenous protein hormones, fragments thereof including epitopes, and synthetic peptides mimicking epitope regions of hormones such as human chorionic gonadotropin can be conjugated to a foreign carrier or otherwise modified so as to produce antibodies in humans ag... | 04/06/2004 |
| 6706681 | HCG liquid formulations The invention refers to liquid pharmaceutical compositions containing hCG stabilised with a polyalcohol or a non-reducing sugar. Preferably, the compositions are stabilised with mannitol. In the preferred embodiments such compositions are aqueous solutions in... | 03/16/2004 |
| 6693074 | Cystine depleted glycoprotein hormones Single-chain forms of the glycoprotein hormones LH, FSH, TSH or CG which are lacking at least one disulfide bridge in the sequence representing the and/or ଲ subunit are useful as agonists or antagonists of the native glycoprotein hormones.... | 02/17/2004 |
| 6689365 | Single-chain fertility hormones with fsh and LH activity Glycosylated or nonglycosylated proteins of the formula FSHଲ-(linker1)n1 -LHଲ(1-X)-(linker2)n2 - wherein FSHଲ is a vertebrate follicle stimulating hormone ଲ subuni... | 02/10/2004 |
| 6635256 | Glycoprotein hormone compositions comprising two ଲ subunits and methods of use thereof Forms of differentially acting glycoprotein hormones are disclosed. These compositions are of the formula... | 10/21/2003 |
| 6620416 | Method for treating HIV The present invention relates to peptides of one or more portions of the human chorionic gonadotropin ଲ-chain as well as methods for treatment and prevention of diseases, including HIV infection, using human chorionic gonadotropin, employing the ... | 09/16/2003 |
| 6600019 | Polypeptides and nucleic acids encoding same The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of ... | 07/29/2003 |
| 6486303 | Method for making hormone heterodimers The present invention relates to a method for preparing heterodimeric analogs of cysteine knot proteins. More specifically, the invention relates to a method for forming a subunit combination of a cysteine knot protein having an -subunit and a ... | 11/26/2002 |
| 6444639 | HCG and derivatives as matrix metalloproteases inhibitors The use of hCG, hCG ଲ-subunit, as well as fragments and active derivatives thereof, or hCG ଲ-core in the preparation of a medicament for the prophylaxis and/or the treatment of pathologies requiring inhibition of the matrix metalloprotease (MM... | 09/03/2002 |
| 6414123 | Method for purifying FSH The present invention provides a method for purifying follicle stimulating hormone (FSH) from biological samples, for example, from human pituitary glands or human postmenopausal urine, wherein the FSH is contaminated with other proteins, by use of dye-li... | 07/02/2002 |
| 6372711 | Methods for assaying human FSH using human FSH receptor The present invention embraces essentially pure human FSH receptor, or a fragment or mutant thereof which binds FSH, DNA encoding said receptor, fragment or mutant, expression vectors comprising said DNA, cells transfected with said expression vectors, an... | 04/16/2002 |
| 6251402 | Use of human chorionic gonadotropin in the treatment of Kaposi's sarcoma The use of hCG Beta-core or hCG fragments, deglycosylated hCG in the treatment of Kaposi's sarcoma is described. Inhibition of tumor production or regression on a variety of KS cell lines is shown. Purified hCG preparations do not inhibit the growth of KS cell... | 06/26/2001 |
| 6242580 | Single-chain forms of the glycoprotein hormone quartet Single-chain forms of the glycoprotein hormone quartet, at least some members of which are found in most vertebrates, are disclosed. The and ଲ subunits of the wild-type heterodimers or their variants or their fragments are covalently linked,... | 06/05/2001 |
| 6238890 | Single chain forms of the glycoprotein hormone quartet Single-chain forms of the glycoprotein hormone quartet, at least some members of which are found in most vertebrates, are disclosed. The and ଲ subunits of the wild-type heterodimers or their variants or their fragments are covalently linked,... | 05/29/2001 |
| 6194177 | DNA encoding a hybrid heterodimeric protein A hybrid protein includes two coexpressed amino acid sequences forming a dimer. Each sequence contains the binding portion of a receptor, such as TBP1 or TBP2, or a ligand, such as IL-6, IFN-댪nd TPO, linked to a subunit of a heterodimeric proteinac... | 02/27/2001 |
| 6193972 | Hybrid heterodimeric protein hormone A hybrid protein includes two coexpressed amino acid sequences forming a dimer. Each sequence contains the binding portion of a receptor, such as TBP1 or TBP2, or a ligand, such as IL-6, IFN-ଲ and TPO, linked to a subunit of a heterodimeric proteina... | 02/27/2001 |
| 6140066 | Methods of cancer diagnosis using a chimeric toxin The present invention relates to methods for cancer diagnosis using a chimeric toxin. In particular, the invention relates to the use of a chimeric toxin composed of gonadotropin releasing hormone (GnRH) and Pseudomonas exotoxin A (PE) to detect a tumor-a... | 10/31/2000 |