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Patent No. 6266829

Combination Beverage Container and Spittoon

A combination beverage container and spittoon includes a bottom portion including outer wall and a first inner wall defining a spittoon space.

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Class 530/388.23 - Binds lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)


Subclass of Class 530 - Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Definition: Subject matter involving a monoclonal antibody or antigen-binding
No. of patents: 500
Last issue date: 04/10/2012


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NumberTitleIssue Date
6015559Fas antagonists
The present invention provides a panel of monoclonal antibodies and binding proteins which specifically bind to human Fas antigen. Some of the antibodies and binding proteins are capable of stimulating T cell proliferation, inhibiting binding of anti-Fas ...
01/18/2000
6001357Method of enhancing wound healing with anti-IL-5 antibody
The invention provides a method of enhancing wound healing, comprising administering an inhibitor of eosinophil influx into a wound site sufficient to result in healing of the wound....
12/14/1999
5998378Compositions for the inhibition of TNF hormone formation and uses thereof
Compounds having proteolytic inhibitory activity useful for treating diseases, particularly as applied to the treatment of sepsis, AIDS or autoimmune diseases, resulting from a decrease in the circulating level of mature protein hormones derived from the ...
12/07/1999
5998586Interleukin-5 specific recombinant antibodies
An effective anti-IL-5 recombinant antibody molecule comprising heavy and/or light chain antigen-binding residues from a donor antibody....
12/07/1999
5994524Polynucleotides which encode reshaped IL-8-specific antibodies and methods to produce the same
The present invention discloses a reshaped human antibody against human IL-8 comprising: (A) L chains each comprising: (1) a human L chain C region; and, (2) an L chain V region comprising a human L chain FR, and an L chain CDR of mouse monoclonal antibody against ...
11/30/1999
5981713Antibodies to intereleukin-1 antagonists
A novel interleukin-1 antagonist active against both IL-1଱ and IL-1ଲ and DNA encoding same/re described. Antibodies specific for the novel IL-1 antagonist and prophylatic, therapeutic and diagnostic uses of the IL-1 antagonist in pathologies a...
11/09/1999
5977323Method of purifying Gro ଲ or Gro ଱ protein using antibodies
Two novel cytokines which are involved in an inflammatory response (inflammatory cytokines) are disclosed. The inflammatory cytokines have been isolated from activated peripheral blood, preferably monocytes adhered to plastic; or peripheral blood leukocyt...
11/02/1999
5976821Monoclonal antibodies specific for human interleukin-5
Monoclonal antibodies which specifically bind to human interleukin-5 (IL-5) are described. The antibodies can be used in assays for IL-5, to purify IL-5, or to characterize IL-5....
11/02/1999
5972718Method of detecting heparin-induced thrombocytopenia
A method of detecting heparin-induced antibodies to complete a diagnosis of heparin-induced thrombocytopenia HITP is disclosed. In one embodiment, this method comprises binding human platelet factor 4 to a linear, non-glycosaminoglycan polymer carrying ne...
10/26/1999
5972335Wound healing
The present invention concerns compositions for promoting the healing of wounds or fibrotic disorders comprising at least one agent specific to either a growth factor or a protein associated therewith in a system and which affects the quantity of active g...
10/26/1999
5969110Antibodies that bind hek ligands
Antibodies specific for a hek-L may be generated, using a hek-L polypeptide or fragment thereof as an immunogen. The antibodies may be monoclonal....
10/19/1999
5969107Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor
The present invention relates to anti-idiotypic antibodies which induce an immune response against tumors, bearing as antigen the epidermal growth factor receptor (EGFR). The antibodies of the invention may mimic said antigen. As preferred embodiment the ...
10/19/1999
5959087Tumour necrosis factor binding ligands
The present invention relates to ligands which bind to human tumour necrosis factor alpha (TNF) in a manner such that upon binding of these ligands to TNF the biological activity of TNF is modified. In preferred forms the ligand binds to TNF in a manner s...
09/28/1999
5959085Human monoclonal antibodies against human cytokines and methods of making and using such antibodies
Human monoclonal antibodies against a human cytokine (such as a human interleukin, e.g., human IL-1଱) and fragments of such antibodies are disclosed. Also disclosed are pharmaceutical compositions and methods employing the human monoclonal antibodie...
09/28/1999
5958774Method for gene transfer into cells activated from a quiescent state
A method is disclosed for gene transfer into a culture of primitive stem cells which comprises a prestimulation step of adding a blocking agent to block at least one inhibitor of a cell cycle of said primitive stem cells. The prestimulation is time-limite...
09/28/1999
5958413Use of antibodies to TNF or fragments derived thereof and xanthine derivatives for combination therapy and compositions therefor
A combined preparation for simultaneous combined, simultaneous separate, or sequential use in the therapy of prophylaxis of disorders associated with undesirable high levels of TNF, e.g. septic or endotoxic shock and immunoregulatory and inflammatory diso...
09/28/1999
5952472Anti-fibroblast growth factor-8 monoclonal antibody
Described is a monoclonal antibody capable of specifically binding to fibroblast growth factor-8 (FGF-8) which is related to growth factors of hormone-dependent tumor cells such as prostatic cancer and breast cancer, and inhibits the FGF-8 activity. The m...
09/14/1999
5939280Immunological assay for quantifying peg-modified human granulocyte colony stimulating factor and monoclonal antibodies used in the assay
An immunological assay for quantifying PEG-modified human granulocyte colony stimulating factor or derivatives thereof in a sample comprising bringing into contact with said sample an antibody which reacts with the human granulocyte colony stimulating fac...
08/17/1999
5929213Antibodies to growth differentiation factor-12
Growth differentiation factor-12 (GDF-12) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-12 polypeptide and polynucleotide sequences....
07/27/1999
5928904DNA encoding recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
Chimeric and humanized IL4 MAbs derived from high affinity MAbs, pharmaceutical compositions containing same, and methods of treatment are provided....
07/27/1999
5925352Method of treating inflammation with antibodies to neutrophil chemotactic factor
An isloated, synthetic preparation of a novel neutrophil-specific chemotactic factor (NCF), monoclonal antibodies having specific binding affinity for NCF and a clone containing the complete cDNA coding sequence for NCF are disclosed....
07/20/1999
5925351Soluble lymphotoxin-ଲ receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
This invention relates to compositions and methods comprising "lymphotoxin-ଲ receptor blocking agents", which block lymphotoxin-ଲ receptor signalling. Lymphotoxin-ଲ receptor blocking agents are useful for treating lymphocyte-mediated imm...
07/20/1999
5922847Methods of purifying hematopoietic cells using an antibody to a stem cell factor receptor
The present invention relates to monoclonal antibodies specific for a cell receptor specific for human stem cell factor (hSCF) as well as pharmaceutical compositions containing such monoclonal antibodies and uses of such monoclonal antibodies....
07/13/1999
5919912Mammalian IAP antibodies and diagnostic kits
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions charact...
07/06/1999
5919911Monoclonal antibodies to stem cell factor receptors
The present invention relates to monoclonal antibodies specific for a cell receptor specific for human stem cell factor (hSCF) as well as pharmaceutical compositions containing such monoclonal antibodies and uses of such monoclonal antibodies....
07/06/1999
5919452Methods of treating TNF଱-mediated disease using chimeric anti-TNF antibodies
Treatment of tumor necrosis factor, TNF, mediated pathologies is provided by administering anti-TNF compounds, such as anti-TNF antibodies and anti-TNF peptides, which compounds are specific for tumor necrosis factor-଱ (TNF଱) or tumor necrosis...
07/06/1999
5916561Monoclonal antibody against CD44v6
The invention concerns an antibody active against an epitope coded by the exon v6 variant of the CD44 gene. The antibody concerned has characteristics superior to those of prior art antibodies and is suitable for use in therapy and diagnosis....
06/29/1999
5914110Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
Chimeric and humanized IL4 MAbs derived from high affinity MAbs, pharmaceutical compositions containing same, and methods of treatment are provided....
06/22/1999
5912136Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
Monoclonal antibodies are provided which are specific for human interleukin-4. Kits and methods are also provided for detecting, measuring and immunopurifying human interleukin-4....
06/15/1999
5911988Method for treating asthma using SCF antibody
This invention provides pharmaceutical compositions comprising anti-SCF antibodies for the reduction of eosinophila in the lungs of mammals. This invention also provides for methods of treating asthma and generating a murine model for asthma....
06/15/1999
5911987Cell surface protein and effector cell bonding reagent
The present invention relates to a bonding reagent, which is characterized in that it comprises a first bonding component specific for the hemagglutinin-neuraminidase molecule of a Newcastle Disease Virus and a second bonding component specific for a cost...
06/15/1999
5907033Anti-oncostatin M monoclonal antibodies
The present invention relates to monoclonal antibodies that define Oncostatin M, a novel cytokine. The monoclonal antibodies of the invention are capable of binding to Oncostatin M, inhibiting Oncostatin M receptor binding, and/or inhibiting Oncostatin M ...
05/25/1999
5891722Antibodies to free IGFBP-1
Antibodies having binding affinity for free IGFBP-1, biological compositions including antibodies having binding affinity for free IGFBP-1, kits for detecting free IGFBP-1 using the antibodies, and cell lines for producing the antibodies are provided. Als...
04/06/1999
5891644Antibody specific for an isolated chemotactic factor from patients with endometriosis
A composition comprising a soluble peptide of about 23 kD to about 29 kD, capable of causing neutrophil and macrophage chemotaxis, and which is substantially similar to chemotactic factor from peritoneal fluid of mammals with minimal or moderate endometri...
04/06/1999
5888705Compositions and method of stimulating the proliferation and differentiation of human fetal and adult pancreatic cells ex vivo
A method of inducing the proliferation and/or differentiation of human adult pancreatic cells entails contacting primary cultures of such cells with Hepatocyte Growth Factor/Scatter Factor (HGF/SF), thereby inducing a proliferation of ଲ-epithelial c...
03/30/1999
5888511Treatment of autoimmune diseases, including AIDS
The present disclosure concerns the treatment of a patient with autoimmune disease, including AIDS, by neutralizing, removing or inhibiting different types of interferons, tumor necrosis factor, HLA class II antigens, IgE, and other pathological factors a...
03/30/1999
5888510Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
Methods for inhibiting synovial cell growth and treating chronic rheumatoid arthritis are provided. The methods comprise administering a pharmaceutical composition comprising an interleukin-6 antagonist, such as an anti-IL-6 receptor antibody, and a physi...
03/30/1999
5874080Anti-IL-8 monoclonal antibodies for treatment of asthma
Methods are provided for the treatment of asthma with anti-IL-8 monoclonal antibodies....
02/23/1999
5872221Antibody having binding specificity to parathyroid hormone related protein (PTHrP) and kit comprising the same
Antibody reagents capable of binding epitopes of PTHrP and a kit for the detection of PTHrP or fragments thereof comprising one or more antibody reagents capable of binding to epitopes of PTHrP....
02/16/1999
5866689Monoclonal antibodies to GP130 protein
Monoclonal antibodies recognizing gp130 protein and binding to the protein to inhibit IL-6 functions completely (that is to the same level as that is the absence of IL-6) when present in enough amount; a hybridoma producing the monoclonal antibody; a proc...
02/02/1999
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