Class 530/388.23 - Binds lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)

Subclass of Class 530 - Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Definition: Subject matter involving a monoclonal antibody or antigen-binding
No. of patents: 500
Last issue date: 04/10/2012

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Number	Title	Issue Date
4902618	Production of hybridoma antibodies for interferon A hybridoma continuous cell line, capable of producing monoclonal antibodies specific for all species of human interferon-alpha, is disclosed. A method for producing hybridomas and monoclonal antibodies with the required specificity is also disclosed. Met...	02/20/1990
4900547	Method to immunize mammals against tumors A general enhancement of the immune system of an animal can be obtained by administration of a T-cell suppressor factor which is idiotypic with regard to any specific antigen when such administration is made in the presence of an effective amount of adjuv...	02/13/1990
4814169	Process for the production of anti-human protein antibody The present invention relates to a process for the production of anti-human protein antibody, comprising induction of the antibody production in non-human warm-blooded animal cells capable of producing said antibody by injecting into a non-human warm-bloo...	03/21/1989
4772572	Hybridomas and monoclonal antibodies to human IL-2 Certain hybridomas preparing monoclonal antibodies to human interleukin-2 (IL-2) which do not cross react with rator mouse IL-2 are disclosed. The secreted monoclonal antibody can be used in immunoassays for human IL-2....	09/20/1988
4751183	Monoclonal antibody that recognizes a structure common to human interleukin-2 (TCGF) and to the light lambda chain of human immunoglobulin and lines of hybridoma cells that produce these monoclonal antibodies Monoclonal antibodies that recognize a structure common to human interleukin-2 and to the light λ chain of human immunoglobulin and lines of hybridoma cells that produce these monoclonal antibodies can be prepared by immunizing animals, especially mice, ...	06/14/1988
4708937	Purified migration inhibitory factor also having colony stimulating factor activity Human migration inhibitory factor (MIF) and salts and derivatives thereof, substantially free of impurities....	11/24/1987
4690893	Hybridoma cell lines producing monoclonal antibodies which specifically bind to mouse interleukin-2 A hybridoma for production of monoclonal antibodies specific for mouse interleukin-2, but which antibodies do not significantly cross-react with human or rat interleukin-2. The hybridoma is a fusion product of a mouse myeloma cell line and from a rat immu...	09/01/1987
4681848	Novel peptide and use thereof The invention relates to novel polypeptide of the formula ##STR1## wherein X is a bond, or a peptide or amino acid residue 1 to 16 amino acids counting from the C terminus of the peptide chain of ##STR2## and Y is a peptide or amino acid residue...	07/21/1987
4666865	Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies Rapid, sensitive and accurate immunoassays for biologically active natural or recombinant human interferon-gamma (huIFN-gamma) based upon monoclonal antibodies which react specifically with epitopes of the biologically active form of huIFN-gamma are discl...	05/19/1987
4599306	Monoclonal antibodies which specifically bind to human immune interferon Disclosed are monoclonal antibody substances specifically immunologically reactive with native and recombinant human immune interferon ("IFN-γ") and with polypeptides having amino acid sequences substantially duplicative of sequences extant in IFN-γ. In...	07/08/1986
4596774	Method of preparing murine monoclonal antibodies against cell-free products of activated human T-lymphocytes A method of preparing simultaneously monoclonal antibodies specific for different cell-free products of activated human T lymphocytes is disclosed. Human T cells are activated in a medium supplemented with mouse serum rather than conventional calf serum. ...	06/24/1986
4558006	A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin Disclosed is a new mouse-mouse hybridoma tumor cell line A.T.C.C. No. HB8209. A monoclonal antibody produced by said cell line is specifically immunologically reactive with erythropoietin and with a polypeptide whose amino acid sequence is substantially d...	12/10/1985
4558005	Monoclonal anti-erythropoietin Hybridoma tumor cell line (ATCC Number CRL 8164). A monoclonal anti-erythropoietin antibody substance, Epoclonalan, produced by said cell line. Use of Epoclonalan in immonological methods for isolation of natural erythropoietin and for quantitative detect...	12/10/1985
4545985	Pseudomonas exotoxin conjugate immunotoxins A method of modifying Pseudomonas exotoxin (PE) with methyl-4-mercaptobutyrimidate is disclosed so that after conjugating the exotoxin to a monoclonal antibody (ab) such as the antibody to the transferrin receptor, the PE-ab conjugate becomes a highly pot...	10/08/1985
4514507	Assay for interferon An assay for interferon comprises two antibodies to interferon, one labelled and at least one being a monoclonal antibody. The non-labelled antibody is suitably attached to a solid support such as polystyrene beads and the labelled antibody is suitably a ...	04/30/1985
4504586	Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1 Murine-derived hybridoma tumor cell lines and monoclonal anti-Colony Stimulating Factor Subclass Number 1 antibody substances produced by these cell lines. Use of said monoclonal antibody substances, alone or in combination, in immunological procedures fo...	03/12/1985
4473493	Hybridoma antibody which inhibits interleukin 2 activity A process for producing anti-IL-2 antibody from hybridoma cells generated by fusing activated, IL-2 immunized, murine lymphocyte cells with neoplastic murine myeloma cells. Fusion is accomplished by mixing the two cell lines together in the presence of a ...	09/25/1984
4423147	Monoclonal antibody to interferon-଱ A monoclonal antibody is described characterized by its specificity to interferon-଱ (leukocyke interferon). Preferably the antibody has specificity to human interferon-଱. The monoclonal antibody is secreted by a hybrid cell formed by the fusio...	12/27/1983
4411993	Hybridoma antibody which inhibits interleukin 2 activity A process for producing anti-IL-2 antibody from hybridoma cells generated by fusing activated, IL-2 immunized, murine lymphocyte cells with neoplastic murine myeloma cells. Fusion is accomplished by mixing the two cell lines together in the presence of a ...	10/25/1983

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Class 530/388.23 - Binds lymphokine, cytokine, or other secreted growth regulatory factor, differentiation factor, or intercellular mediator specific for a hematopoietic cell (e.g., interleukin, interferon, erythropoietin, etc.)