Did You Know...
...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 4597966 | Histidine stabilized immunoglobulin and method of preparation Histidine-stabilized immunoglobulin preparations and a method for their manufacture are disclosed. The present invention is particularly well suited for stabilization of human gamma globulin (IgG) preparations having a relatively low protein content. Pref... | 07/01/1986 |
| 4594245 | Augmenting factors for human antibody production and process for peparing the same Augmenting factors for human antibody production having a molecular weight of 2,000-4,000 are prepared from the supernatant of cultured human lymphocytes. Nylon wool-adherent cells of human lymphocytes are separated from nylon wool-passed cells, and are t... | 06/10/1986 |
| 4579840 | Method of blocking immune complex binding to immunoglobulin Fc receptors Methods and peptides for blocking immunogloblin Fc receptors are set forth.... | 04/01/1986 |
| 4564600 | Allergens and antibodies from allergen extracts and pooled serum Allergenic factors are isolated from antigen extracts by preparing a column with pooled serum from patients with allergy to a given allergen system and passing over this column a pool of allergen extracts from different sources. Allergen specific immunogl... | 01/14/1986 |
| 4550019 | Manufacture and use of fowl egg antibodies Immunological preparations are prepared by immunizing hens with an immunogen having a molecular or particle weight of at least 30,000, to a stage of hyper-immunization at which there occurs a plateau-like levelling-off of the antibody content of the serum... | 10/29/1985 |
| 4533634 | Tissue culture medium A growth factor containing serum is disclosed which is derived from natural bovine serum is disclosed which is by precipitating a first solids fraction from natural bovine serum by adding ammonium sulfate to about 25% saturation to give a first solids fra... | 08/06/1985 |
| 4522751 | Method for producing a preparation containing factor VIII (AHF) There is described a method for producing a preparation having a high content of Factor VIII (AHF), i.e. with a specific activity of at least 1.5 units of Factor VIII/mg protein, immunoglobulin G (IgG) of from 15 to 30 mg/1000 units of Factor VIII and fib... | 06/11/1985 |
| 4493928 | Crosslinked chitin derivatives A novel crosslinked polymeric substance and a process for preparing the novel crosslinked polymeric substance are disclosed, the novel crosslinked polymeric substance being prepared from natural chitin or regenerated chitin and the polymeric substance hav... | 01/15/1985 |
| 4490290 | Process for the recovery of immunoglobulins A process for the recovery of immunoglobulins of high purity and potency from milk, in which process milk is passed through a re-usable immunoadsorbent column comprising an insoluble carrier material to which is bound a low-affinity monoclonal antibody sp... | 12/25/1984 |
| 4489133 | Two-dimensional crystallization technique Methods and compositions involving two-dimensional ordering of organic polar solvent soluble organic macromolecules. Lipid monolayer forming molecules are bound covalently or non-covalently to organic macromolecules soluble in polar solvents, whereby the ... | 12/18/1984 |
| 4486341 | Fractionation of blood plasma There is provided in accordance with practice of this invention a process for separating protein fractions from a solution containing proteins and an apparatus for practicing the process. The process and apparatus involve withdrawing from a suspension tan... | 12/04/1984 |
| 4479895 | Immunoglobulin half-molecules and process for producing hybrid antibodies A process for preparing covalent hybrid antibodies is provided. These antibodies are obtained by the ordered covalent hybridization of intact immunoglobulin molecules. The generation of half-molecules from different IgG antibodies by reductive or S-sulfon... | 10/30/1984 |
| 4474690 | Method for the recovery of peptide-containing compound and means therefor A method is disclosed for the recovery of a peptide-containing compound from a solution by the use of a ligand attached to a carrier which ligand is capable by biospecific affinity of fixing onto the peptide-containing compound. The carrier which, for exa... | 10/02/1984 |
| 4472303 | Blood purification method Treatment of the blood by means of a blood purification device comprising packed, substantially spherical, smooth-surfaced, porous granules having at least 0.1 μmole/m2 of the silanol group on the surface thereof, a blood inlet and a blood out... | 09/18/1984 |
| 4465670 | Method for the treatment of systemic lupus erythematosus and primary glomerulonephritis and agent therefor A method for the treatment of diseases such as systemic lupus erythematosus and primary glomerulonephritis by administering a γ-globulin having Fc fragment to patients suffering from such diseases in parenteral route (particularly intravenously) and a pr... | 08/14/1984 |
| 4447355 | Method for stabilizing a tumor necrosis factor and a stable aqueous solution or powder containing the same A method for stabilizing a Tumor Necrosis Factor (TNF), which comprises adding at least one member selected from the group consisting of an albumin, a gelatin, a globulin, a protamine and a salt of protamine to an aqueous solution or powder containing TNF... | 05/08/1984 |
| 4436658 | Process of extraction of lactoferrine and immunoglobulins of milk From an aqueous medium derived from milk substantially free from caseins, proteins are extracted, particularly lactoferrine and immunoglobulins, by adsorption on a solid support. The aqueous medium is weakly basic, while elution is effected by means of an... | 03/13/1984 |
| 4421684 | Column for adsorption of blood proteins A column for adsorption of blood proteins is disclosed which comprises a blood inlet and a blood outlet each with a filter, and a porous material packed between both the filters, which material has a mean pore diameter (D) of 30-3,000 amgstroms with the v... | 12/20/1983 |
| 4416813 | Artificial carrier for immobilization of biological proteins A novel artificial carrier is disclosed which is prepared from gelatin, a water-soluble polysaccharide, a sodium metaphosphate and an aldehyde. The carrier can be used to immobilize antibodies, antigens or enzymes. Immobilized antigens and antibodies can ... | 11/22/1983 |
| 4415493 | Immune modulator peptides A class of 23 or 24 amino acid peptides available by chemical synthesis or by enzymatic and chemical cleavage of IgG is described. The compounds are useful in modulating the immune response.... | 11/15/1983 |
| 4412990 | Composition having enhanced opsonic activity There is disclosed a pharmaceutical composition for therapeutic use comprising an immune globulin and fibronectin in amounts sufficient to produce an opsonic activity in the composition that is greater than the additive opsonic activity of the individual ... | 11/01/1983 |
| 4388232 | Method of producing plasma fractions free of side-effects using fast-reacting antithrombin In a method of producing plasma fractions free of side-effects by purification and step-wise enrichment of plasma proteins in the presence of calcium-binding anticoagulants, also fast reactive (avid) antithrombin is present, wherein a concentration of the... | 06/14/1983 |
| 4384954 | Column for adsorption of blood proteins A column for adsorption of blood proteins is disclosed which comprises a blood inlet and a blood outlet each with a filter, and a porous material packed between both the filters, which material has a mean pore diameter (D) of 30-3,000 angstroms with the v... | 05/24/1983 |
| 4382028 | Separation of plasma proteins from cell culture systems Plasma proteins are separated from cell culture systems such as, for example, fermentation broths of microbial cell cultures and expended media of mammalian cell cultures, by adsorption with water-insoluble, cross-linked polyelectrolyte copolymers.... | 05/03/1983 |
| 4379083 | Process for the preparation of blood plasma fractions A precipitation process for the preparation of blood plasma constituents is disclosed, wherein the plasma to be fractionated and the precipitant are circulated in a closed system.... | 04/05/1983 |
| 4357272 | Recovering purified antibodies from egg yolk Immunological preparations are prepared by immunizing hens with an antigen, preferably to a stage of hyperimmunization. The eggs of the immunized hens are collected, the yolk is separated from the eggs, followed by separation of the lipid content of the y... | 11/02/1982 |
| 4344938 | Agent for the treatment of allergic reactions What are disclosed are a method for the prophylaxis and therapy of allergic reactions and an agent therefor, said agent containing immunoglobulins of class IgG or fragments thereof which have been immunologically modified in their Fc part.... | 08/17/1982 |
| 4322275 | Fractionation of protein mixtures This invention relates to the separation of complex protein mixtures by lowering (desalting) or by raising (salting-out) their electrolytic (ionic) concentration by electrodialysis followed by chilling, pH adjustment, filtration, and/or centrifugation and... | 03/30/1982 |
| 4321192 | Fractionation of protein mixtures by salt addition followed by dialysis treatment A process is described for the fractionation of solutions of protein mixtures which includes the steps of subjecting such solutions to "salting-out", separation of the resulting turbidity, subsequent removal of the "salting-out" agent from the supernatant... | 03/23/1982 |
| 4307071 | Analytical reagent and method A reagent is disclosed for determining the concentration of a ligand in blood serum. The reagent includes a protenaceous, three-dimensional, serum-insoluble complex which is readily collected by centrifugation, the complex comprising non-specific immunogl... | 12/22/1981 |
| 4279884 | Process for preparation of antisera A process for the preparation of a high titre antiserum of a desired specificity includes the steps of, a first immunological reaction between a serum sample which includes a protein to which the required antiserum is specific and an antiserum sample know... | 07/21/1981 |
| 4276140 | Electrodialysis apparatus and process for fractionating protein mixtures Apparatus and process for the fractionation of liquid solutions of protein mixtures which includes the steps of subjecting such solutions to electrodialysis (ED) while in the pH range of about between 5-8 until a partial or a substantially complete desalt... | 06/30/1981 |
| 4246351 | Protein adsorbent A novel protein adsorbent consisting essentially of a porous copolymer obtained by copolymerizing a monomer mixture comprising at least one cyano group-containing monomer and at least one cross-linkable monomer, said copolymer having an average pore diame... | 01/20/1981 |
| 4225486 | Aloctin A A glycoprotein isolated from Aloe, a plant belonging to Liliaceae, having a molecular weight of 1.8×104 and a ratio of protein to sugar of 8 to 2 by weight; yielding only a single band upon SDS-polyacrylamide gel electrophoresis without 2-merc... | 09/30/1980 |
| 4216205 | Process of preparing a serum protein composition for intravenous application A process of preparing a serum protein composition for intravenous application or administration, in which process, starting from a human blood protein solution, a stabilized, universally applicable preparation or composition is prepared which contains di... | 08/05/1980 |
| 4172827 | Method for concentration and purification of antigens and antibodies In carrying out a purification and/or concentration step of antigens or antibodies, a substrate is immersed in a first aqueous medium containing a specifically reacting antigen to coat said substrate with a monomolecular layer of said specifically reactin... | 10/30/1979 |
| 4110320 | Method of fractionating and separating proteins Improvement in a method for the fractionation and separation of proteins by dsorption on an organic gel and elution with a descending ammonium sulfate gradient, the improvement comprising treating a solution of the proteins with ammonium sulfate down to a ... | 08/29/1978 |
| 4100149 | Method of separating proteins by ion exchange A method of separating proteins by ion exchange comprising putting a solution of proteins into contact with an ion exchange resin consisting of a porous inorganic carrier coated with a cross-linked polymer containing or carrying anion exchanging groups --... | 07/11/1978 |
| 4097473 | Production of serum albumin A serum albumin fraction is prepared in high yield and purity from plasma and other albumin-containing blood protein fractions by contacting with a resinous polymeric material having a high capacity for adsorption of albumin, heating at 65° C-72° C for ... | 06/27/1978 |
| 4086222 | Method of isolating albumin from blood products This invention relates to a new method of isolating highly purified albumin in high yields from plasma products. According to the invention a particular plasma fraction, containing albumin in dissolved form and being essentially free from the coagulation facto... | 04/25/1978 |
