Did You Know...
...that when IBM conducted a market study of Chester Carlson's invention in 1959, the company concluded that it would take only 5000 units of his new product to saturate the market? IBM therefore declined to be part of the new product introduction. Too bad for IBM. Carlson's invention was the xerography process, and his new product was the beginning of the Xerox Corporation. It is estimated that every day, worldwide, 3,000,000,000 copies are made!!
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| Number | Title | Issue Date |
| 4348316 | New protein PP15, a process for its preparation and its use What are disclosed are a protein, PP15, useful for preparing antisera and as an immunosuppressive agent, and a method for isolating the pure protein from human placentas.... | 09/07/1982 |
| 4337240 | Denatured albumin complexes for radioscintigraphic imaging and evaluation of reticuloendothelial systems Small sized material (less than 0.2 μm, preferably less than 0.1 μm) comprising a complex of (1) denatured albumin, particularly human serum albumin and (2) a metal reducing agent, particularly a stannous reducing agent, preferably formed in the presenc... | 06/29/1982 |
| 4322275 | Fractionation of protein mixtures This invention relates to the separation of complex protein mixtures by lowering (desalting) or by raising (salting-out) their electrolytic (ionic) concentration by electrodialysis followed by chilling, pH adjustment, filtration, and/or centrifugation and... | 03/30/1982 |
| 4313871 | Antigen for early pregnancy test and contraceptive vaccine Antisera suitable for detecting the presence of human chorionic gonadotropin in body fluids by immunoassay are prepared by administering to a host animal an antigen comprising the ଲ-subunit of human chorionic gonadotropin which has been modified by ... | 02/02/1982 |
| 4310455 | Antigen for early pregnancy test and contraceptive vaccine Antisera suitable for detecting the presence of human chorionic gonadotropin in body fluids by immunoassay are prepared by administering to a host animal an antigen comprising the ଲ-subunit of human chorionic gonadotropin which has been modified by ... | 01/12/1982 |
| 4297344 | Blood coagulation factors and process for their manufacture A process for stabilizing the coagulation factors II, VIII, XIII, antithrombin III and plasminogen against heat is described. The preparations obtained according to this process are practically free from coagulable fibrinogen.... | 10/27/1981 |
| 4281065 | Phencyclidine conjugates to antigenic proteins and enzymes Phencylidine, PCP, derivatives having a non-oxo carbonyl functionality linked directly or through a linking group to the phenyl ring are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjuga... | 07/28/1981 |
| 4275160 | Imipramine derivatives and poly(amino acid) conjugates Imipramine functionalized compounds are provided for conjugation to antigenic compounds, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immunoassays for the... | 06/23/1981 |
| 4268435 | Chorionic gonadotropin derived antigen for early pregnancy test and contraceptive vaccine Antisera suitable for detecting the presence of human chorionic gonadotropin in body fluids by immunoassay are prepared by administering to a host animal an antigen comprising the ଲ-subunit of human chorionic gonadotropin which has been modified by ... | 05/19/1981 |
| 4261974 | Valproic acid immunogen conjugates and antibodies thereto Reagents for use in binding assays, particularly immunoassays, to determine valproic acid in liquid media such as serum. Such reagents include antibody to valproic acid and ଲ-galactosyl-umbelliferone-valproic acid conjugates. Also provided are compo... | 04/14/1981 |
| 4256629 | Antigen for early pregnancy test and contraceptive vaccine Antisera suitable for detecting the presence of human chorionic gonadotropin in body fluids by immunoassay are prepared by administering to a host animal an antigen comprising the ଲ-subunit of human chorionic gonadotropin which has been modified by ... | 03/17/1981 |
| 4225487 | Affinity chromatography of Vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers Columns of polysaccharide, e.g., agarose, derivatives comprising covalently bonded gangliosides quantitatively adsorb the 125 I-labeled cholera toxin of chromatographed samples. The most preferred derivatives are those wherein the gangliosides ... | 09/30/1980 |
| 4223013 | Amitriptyline conjugates to antigenic proteins and enzymes Amitriptyline functionalized compounds are provided for conjugation to antigenic compositions, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immunoassays f... | 09/16/1980 |
| 4216143 | Soluble non-ferrous metal proteinates Non-ferrous metal proteinates or chelates of essential bivalent metals with hydrolyzed protein are rendered soluble without destroying the chelate and are more readily assimilated by plants and animals.... | 08/05/1980 |
| 4216144 | Soluble iron proteinates Iron proteinates or chelates of iron with hydrolyzed protein which are usually insoluble are rendered soluble without destroying the chelate and are more readily assimilable by plant and animals.... | 08/05/1980 |
| 4215102 | Cytochemical agents and methods for the detection of steroid hormone receptors in human tissues A cytochemical agent and method for the detection and identification of estrogen or progesterone receptor cells in carcinomas of the breast is described, involving an estrogen-protein-fluorochrome conjugate or a progesterone-protein-fluorochrome agent whi... | 07/29/1980 |
| 4213894 | Diphenylhydantoin immunogen conjugates Reagents for use in binding assays, particularly immunoassays, to determine diphenylhydantoin and for preparing reagents employed in such assays, including ଲ-galactosyl-umbelliferone-diphenylhydantoin conjugates, diphenylhydantoin immunogens, and N | 07/22/1980 |
| 4213964 | Diphenylhydantoin antibodies Reagents for use in binding assays, particularly immuno assays, to determine diphenylhydantoin and for preparing reagents employed in such assays, including ଲ-galactosyl-umbelliferone-diphenylhydantoin conjugates, diphenylhydantoin immunogens, and N... | 07/22/1980 |
| 4211766 | Cancer associated polypeptide antigen compositions A process for the isolation of cancer associated polypeptide antigen mainly by several steps of gel filtration and pH-gradient elution; a cancer associated polypeptide antigen based on a single peptide chain and denaturating irreversibly at pHs exceeding ... | 07/08/1980 |
| 4203893 | Coupling products of cytidine-diphosphocholine and amino-compounds for pharmaceutical use The products of the invention are obtained by a method which consists of: oxidizing cytidine-diphosphocholine, fixing the dialdehyde obtained by the preceding oxidation of the ribose of the cytidine on NH2 groups of the amino compound in alkali... | 05/20/1980 |
| 4195126 | Albumin-dye complex for fatty acid determination An albumin-dye complex is prepared containing serum or plasma albumin which is substantially free of endogenous fatty acids and which has been complexed with a fatty acid and dye which dye may be displaced from the albumin-dye complex by free fatty acids.... | 03/25/1980 |
| 4183847 | Enzymatically hydrolyzable, serum-soluble cholesterol compounds and method for their preparation Water and serum soluble cholesterol compounds are prepared by reactively combining certain esters of cholesterol with a solubilizing agent selected from the group consisting of peptides, proteins, water soluble polycarboxylic acids, organic and inorganic ... | 01/15/1980 |
| 4182856 | Reagents for use in binding assays to determine diphenylhydantoin Reagents for use in binding assays, particularly immunoassays, to determine diphenylhydantoin and for preparing reagents employed in such assays, including ଲ-galactosyl-umbelliferone-diphenylhydantoin conjugates, diphenylhydantoin immunogens, and N | 01/08/1980 |
| 4175074 | Serum-soluble cholesterol compounds and method for their preparation Water and serum soluble cholesterol compounds are prepared by reactively combining a lower acid ester of cholesterol with a peptide or protein as solubilizing agent. The water-soluble cholesterol compounds can be lyophilized and added to serum as a standa... | 11/20/1979 |
| 4160018 | Stabilized cancer associated polypeptide antigen and preparation thereof A process for the isolation of cancer associated polypeptide antigen mainly by several steps of gel filtration and pH-gradient elution; a cancer associated polypeptide antigen based on a single peptide chain and denaturating irreversibly at pHs exceeding ... | 07/03/1979 |
| 4126605 | Process of improving the compatibility of gamma globulins A process for providing gamma globulin with improved intravenous compatibility. In the process, gamma globulin precipitated from blood or blood products is dissolved in an aqueous solution containing a hydrocolloid. The hydrocolloid is capable of forming ... | 11/21/1978 |
| 4125492 | Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers Columns of polysaccharide, e.g., agarose, derivatives comprising covalently bonded gangliosides quantitatively adsorb the 125 I-labeled cholera toxin of chromatographed samples. The most preferred derivatives are those wherein the gangliosides ... | 11/14/1978 |
| 4124576 | Method of producing intravenously injectable gamma globulin An improved process is provided for the preparation of a gamma globulin suitable for intravenous administration from the readily available Fraction II or II + III plasma protein paste or from the corresponding fractions originating from placental extracts... | 11/07/1978 |
| 4101380 | Process for the cross-linking of proteins The invention relates to a process for the cross-linking of proteins wherein the proteins to be cross-linked are reacted with a cross-linking agent selected from the group consisting of: (a) water soluble poly(ethylene oxide) derivatives of the general formula... | 07/18/1978 |
| 4100149 | Method of separating proteins by ion exchange A method of separating proteins by ion exchange comprising putting a solution of proteins into contact with an ion exchange resin consisting of a porous inorganic carrier coated with a cross-linked polymer containing or carrying anion exchanging groups --... | 07/11/1978 |
| 4085095 | Clottable fibrinogen free Factor VIII product and process Lyophilizable, clottable fibrinogen free, Factor VIII is produced on a commercial scale from a fibrinogen containing Factor VIII concentrate by sequentially, precipitating a major portion of the clottable fibrinogen by the addition of an ethylene oxide-po... | 04/18/1978 |
| 4067963 | Substance acting to prevent and improve cerebral function disorder and process for preparing the same Substance acting to prevent and improve cerebral function disorder which is prepared by treating albumin with a fatty acid and hydrolizing the modified albumin is described.... | 01/10/1978 |
| 4058511 | Tegretol antigens and antibodies Derivatives of dibenz[b,f]azepine drugs are provided for preparation of antigens and antibodies, the antibodies finding use in immunoassays for the dibenz[b,f]azepine drugs. Specifically, N-oxoaliphatic substituted carbamoyl dibenz[b,f]azepine compounds a... | 11/15/1977 |
| 4046722 | Immunological materials The present invention is concerned with a cytotoxic agent comprising an immunoglobulin specific for antigens on the surface of the cell to be killed having 1-10 polymer carrier molecules covalently bonded thereto and the polymer carrier having 5-500 molec... | 09/06/1977 |
| 4043989 | Oxazepam derivatives for immunoassay reagents Compounds are provided for use in the preparation of reagents which can be used in immunoassays for benzdiazepines, particularly as their urinary metabolites. The compounds are non-oxo-carbonyl derivatives conjugated to the 3-position of the benzdiazepine... | 08/23/1977 |
| 4043997 | Method for isolating albumin using insoluble supports coupled to a dye A method for the isolation of albumin which allows the selective adsorption and substantially quantitative elution of albumin from mixtures containing the same. The method comprises contacting a solution which contains albumin with a member of a series of... | 08/23/1977 |
| 4027013 | Clottable fibrinogen free factor VIII and albumin product and process Lyophilizable, clottable fibrinogen free, Factor VIII is produced on a commercial scale from a fibrinogen containing Factor VIII concentrate by sequentially, precipitating a major portion of the clottable fibrinogen by the addition of an ethylene oxide-po... | 05/31/1977 |
| 4016149 | Selective removal of albumin from blood fluid and compositions therefore Certain compositions have been prepared by the reaction of certain dyes of the class generally known as Color Index reactive dyes with certain support phases. The dyes utilized for said compositions all possess the general sulfanilido-triazidinyl-sulfoary... | 04/05/1977 |
| 4016147 | Method for preparation of low-phenylalanine plastein Method for the preparation of a low-phenylalanine plastein comprising hydrolyzing stepwise a certain albumin or globulin protein with an endopeptidase having an affinity for the aromatic acid components, and an exopeptidase, subjecting the hydrolyzate thu... | 04/05/1977 |
| 3960827 | Cancer associated polypeptide antigen, process for its preparation, process for preparing antibodies, process of cancer diagnosis and composition useful as an immunizing agent A process for the isolation of cancer associated polypeptide antigen mainly by several steps of gel filtration and pH-gradient elution; a cancer associated polypeptide antigen based on a single peptide chain and denaturating irreversibly at pHs exceeding ... | 06/01/1976 |
