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| Number | Title | Issue Date |
| 8158755 | Production method of gelatin particles A method of producing gelatin particles, including immersing a discharge spout in a hydrophobic solvent, discharging an aqueous gelatin solution from a nozzle tip into the hydrophobic solvent, and lifting, after discharging, the nozzle from the hydrophobic solvent, ... | 04/17/2012 |
| 7855273 | Method for manufacturing gelatin with reduced endotoxin content and low endotoxin gelatin A method of manufacturing gelatin with reduced endotoxin content. The method comprises processing a starting material gelatin-containing solution containing gelatin and an endotoxin with an ultrafiltration film having a molecular weight cut-off falling within a rang... | 12/21/2010 |
| 7595377 | Substantially non-immunogenic injectable collagen The invention provides an article of manufacture comprising a substantially non-immunogenic injectable collagen for implantation into humans. The invention further provides methods for preparing injectable collagen material by removing collagen-containing material f... | 09/29/2009 |
| 7297777 | Process of purification of hCG and recombinant hCG purified by that method A process for the purification of recombinant human Chorionic Gonadotropin (hCG) from a sample of crude recombinant hCG in the supernatant of CHO cells comprises the combined use of ion-exchange chromatography and reverse phase HPLC. The ion-exchange chromatography ... | 11/20/2007 |
| 7285637 | Method for the preparation of a non-woven silk fibroin fabrics A process for producing non-woven silk fiber fabrics comprises the following steps: a) obtaining silk fibroin, for example either from silk cocoons, or silk textiles or waste silk; b) removing the sercin layer covering the silk fibroin fibers, when present; c) break... | 10/23/2007 |
| 7164010 | Molecular magnetic protein A highly magnetically aligned metallothionein (MT) containing manganese (Mn) and cadmium (Cd) has been synthesized. The metallotionein has a formula of Mnx Cd7−x MT with x being in the range of 1 to 6. Its size and biological functions are si... | 01/16/2007 |
| 7132110 | Tissue repair compositions and methods for their manufacture and use An osteogenic composition is prepared by a process including the steps of subjecting demineralized bone to an extraction medium to produce an insoluble extraction product and a soluble extraction product, separating the insoluble extraction product and the soluble e... | 11/07/2006 |
| 7098315 | Method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge A method of preparing a collagen sponge comprises mixing air into a collagen gel, so as to obtain a collagen foam which is dried. From the dried product thereby obtained, collagen sponge is obtained by isolating parts of sponge with a chamber diameter of more than 0... | 08/29/2006 |
| 7094580 | Methods for producing pure perlecan and other heparan sulfate proteoglycans A method of perlecan isolation (from the EHS tumor) which produces “clean” (i.e. substantially “pure”) perlecan is disclosed. Clean perlecan is thus produced in sufficient quantities for use in a number of different in vitro and in vivo assays. In addition, ... | 08/22/2006 |
| 7064187 | Substantially non-immunogenic injectable collagen The invention provides an article of manufacture comprising a substantially non-immunogenic injectable collagen for implantation into humans. The invention further provides methods for preparing injectable collagen material by removing collagen-containing material f... | 06/20/2006 |
| 7026167 | Systems and methods for the analysis of protein phosphorylation The present invention relates to a method of applying mass spectrometry to analyzing peptides or proteins, especially in the proteome setting. More particularly, the invention relates to a mass spectrometry-based method for detection of protein/peptide phosphorylati... | 04/11/2006 |
| 6995242 | Process for producing insoluble and soluble collagen protein products from poultry skins and use thereof A method of extracting and fractionating collagen-rich proteinaceous materials and derivatives from poultry skin tissue and the development of the proteinaceous materials to collagen-based protein ingredients that can function as meat replacer, texturizer, binder/fi... | 02/07/2006 |
| 6974679 | Support with collagen base for tissue engineering and manufacture of biomaterials The invention relates to a method of in vitro testing of the efficacy of a potentially active substance comprising monitoring the effect of said potentially active substance on an artificial skin, comprising a composite product forming a collagen support comprising ... | 12/13/2005 |
| 6936455 | Production of heterologous proteins using an Npro autoprotease of a pestivirus and inclusion bodies The present invention relates to a process for the recombinant production of a desired heterologous polypeptide with a clearly defined homogenous N-terminus in a bacteria host cell. A fusion comprising a peptide with the autoproteolytic activity of an autoprotease N... | 08/30/2005 |
| 6916910 | Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof The present invention relates to a process for the production of marine invertebrate type V telopeptide containing collagen preparations from marine invertebrates, compositions containing preparations, and methods of using these preparations. The collagen preparatio... | 07/12/2005 |
| 6911071 | Photographic element containing acid processed gelatin The present invention relates to an imaging member comprising poultry gelatin. In one embodiment, the poultry gelatin is located preferably in at least one layer in the upper half of said imaging member comprising poultry gelatin. Another embodiment provides an aque... | 06/28/2005 |
| 6884602 | Expression of alkaline phosphatase in yeast This invention involves a process for selecting and producing eukaryotic alkaline phosphatase in yeast. Yeast cells are subjected to multiple transformations using a vector comprising a first resistance marker gene and the alkaline phosphatase gene. Those strains th... | 04/26/2005 |
| 6827948 | Method and compositions for processing poultry feathers The present invention provides a method and compositions for processing poultry feathers. In one embodiment, the method for processing poultry feathers comprises contacting a plurality of poultry feathers having an average particle size with a detergent capable of i... | 12/07/2004 |
| 6706467 | Coating fluid for imaging element comprising solubilized collagen gelatin colloidal dispersion An aqueous coating fluid is described comprising gelatin at a concentration of at least 1 wt % and a colloidal particle dispersed material phase at a volume fraction of at least 0.01, wherein at least 20% of the gelatin comprises a gelatin prepared from hydrolysis o... | 03/16/2004 |
| 6689556 | Method of producing water-soluble chain-extended gelatin, gelatin produced by the method, and silver halide photographic light-sensitive material containing the gelatin Disclosed is a method of producing a water-soluble chain-extended gelatin subjecting a source a source gelatin having a first isoelectric point, in aqueous solution, to a partial crosslinking reaction to form a reaction mixture comprising a partially cros... | 02/10/2004 |
| 6689595 | Crystallization and structure determination of Staphylococcus aureus thymidylate kinase An unliganded form of Staphylococcus aureus thymidylate kinase (S. aureus TMK) has been crystallized, and the three dimensional x-ray crystal structure has been solved to 2.3 Å resolution. The x-ray crystal structure is useful for solving the structure o... | 02/10/2004 |
| 6649740 | Hydratable form of keratin for use as a soil amendment A hydratable oxidized keratin composition comprising one or more metal ion species capable of absorbing water to form a hydrogel. The keratin material is useful as a soil amendment providing organic and inorganic nutrients. The keratin material is also us... | 11/18/2003 |
| 6589326 | Coating fluid for imaging element comprising solubilized collagen gelatin and hardener An aqueous coating fluid is described comprising gelatin at a concentration of at least 1 wt % and gelatin hardener at a level from 1-200 effective μmole hardener per gram of coating fluid, wherein at least 20% of the gelatin comprises a gelatin prepared... | 07/08/2003 |
| 6545133 | Methods for purifying telomerase This invention provides purified telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of matrices that bind molecules bearing negative charges, matrices that bind molecules bearing positive cha... | 04/08/2003 |
| 6361802 | Method and apparatus for the recovery of non-solvent type fills from gelatin capsules Method and apparatus for recovering non-solvent fills from a gelatin-containing material by adding the gelatin-containing material to a suitable solvent to form a mixture including a solvent phase and a phase containing said non-solvent fill and then sepa... | 03/26/2002 |
| 6344437 | Medicine drink food and feed having an action of strengthening bone The present invention is to provide a novel medicine, drink, food or feed having an action of strengthening bone. More specifically, the present invention is to provide a medicine, drink, food or feed combined with collagen, fraction containing collagen o... | 02/05/2002 |
| 6316598 | Water absorbent keratin and gel formed therefrom A hydratable, highly absorbent keratin solid fiber or powder capable of absorbing a large weight excess of water may be produced by partially oxidizing hair keratin disulfide bonds to sulfonic acid residues and reacting the sulfonic acid residues with a c... | 11/13/2001 |
| 6245500 | Method for gelling a photographic coating composition and an apparatus of the same A method of cooling a photographic coating composition in a sol state is disclosed. The composition that includes photographic emulsion, an emulsified material or gelatin solution, or comprising combinations thereof is continuously cooled by employing hea... | 06/12/2001 |
| 6166187 | Method of concentrating prion proteins in blood samples A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected to separation processing (e.g. centrifugation) to obtain ... | 12/26/2000 |
| 6100381 | Enzyme method of manufacturing gelatin The present invention is a process for the manufacture of gelatin which includes providing a collagen containing material and demineralizing the collagen containing material to produce ossein. An enzyme solution containing protease at a concentration of a... | 08/08/2000 |
| 6080843 | Gelatin and method of manufacture The present invention is a gelatin composed of a high molecular weight fraction (>250,000) of from 0 to 25 wt %, a beta fraction (150,000-250,000) of from 0 to 20 wt % and an alpha fraction (50,000-150,000) of from 15 to 55 wt %. The gelatin has a Gel str... | 06/27/2000 |
| 6037451 | Method of degreasing bone for gelatin manufacture The present invention is a process for degreasing bone for the manufacture of gelatin. A lipase solution at a concentration of greater than 0.1 ppm is added to a collagen containing material and treated for a time sufficient to solubilize the fat containe... | 03/14/2000 |
| 5977056 | Treatment of thrombotic events A method for preventing the formation of platelet-rich clots or thrombus, and for deaggregating platelet-rich clots or thrombus, using hementin, a polypeptide derived from leech salivary glands. Hementin may be administered for this purpose in a pharmaceu... | 11/02/1999 |
| 5955578 | Polypeptide-polymer conjugates active in wound healing A conjugate of a synthetic polypeptide containing RGD or (dR) GD and a biodegradable polymer, such as hyaluronic acid or chondroitin sulfate is disclosed. Methods of making the conjugate and using it to aid wound healing by providing a temporary matrix ar... | 09/21/1999 |
| 5948432 | Keratin-based sheet material for biomedical applications and method of production A sheet wound dressing formed of cross linked keratin. An insoluble, largely Beta keratin fraction from human hair is acidified to a low pH, preferably less than about 3, which partially solubilizes the keratin by weakening hydrogen bonds. The suspension ... | 09/07/1999 |
| 5945001 | Method for the purification and recovery of waste gelatin using diafilters A process for the recovery and purification of waste gelatin, especially from the manufacture of soft gelatin capsules includes the steps of effecting dissolution of the gelatin and other water-soluble components of the waste in a solvent such as deionize... | 08/31/1999 |
| 5908921 | Method of manufacturing gelatin The present invention is a process for the manufacture of gelatin which includes providing a collagen containing material and demineralizing the collagen containing material to produce ossein. The ossein is added to a water solution containing at least 3%... | 06/01/1999 |
| 5889149 | Purified PDGF AB isoform and method of making it Monoclonal antibodies (MAbs) capable of binding to native PDGF, and MAbs capable of specifically binding to the PDGF-AA, PDGF-BB and PDGF-AB isoforms are disclosed. The subject MAbs may be used in the detection or purification of native PDGF or selected P... | 03/30/1999 |
| 5877287 | Method for producing gelatin In a method for producing gelatin from collagen-containing raw material, the raw material is ground and mixed with water to form a slurry; the slurry is treated with an acid and heated in order to expose the collagen in the raw material; the pH and the te... | 03/02/1999 |
| 5824640 | Substances of polypeptide nature useful in human therapy Substances of polypeptide nature are obtainable by extraction with HClO4 and 3M KCl from animal tissue homogenates. The substances have the characteristics of (a) molecular weights ranging from 10,000 to 50,000 daltons (by polyacrylamide gel el... | 10/20/1998 |
