Did You Know...
...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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| Number | Title | Issue Date |
| 4101537 | Octapeptides and methods for their production New octapeptides having the formula X-R1 -Trp-Ser(benzyl)-Tyr(benzyl)-R2 -Leu-Arg(R)-Pro-R3 -Y wherein X is a protective group, R is hydrogen or a protective group, R1 is a single bond, Gln, D-Leu or D-Val, R | 07/18/1978 |
| 4098777 | Process for the preparation of pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn This invention is directed to the chemical process for the preparation of the polypeptide, pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn and to intermediates in said process. The polypeptide prepared by the present process is useful in the treatment of aut... | 07/04/1978 |
| 4093611 | Octapeptides and methods for their production New octapeptides having the formula X-R-Pro-His(benzyl)-His(benzyl)-R1 -Trp-D-Ala-Y wherein X is a protective group, R is Pro or Gln; R1 is Tyr(benzyl)-Ser(benzyl) or Ser(benzyl)-Pro and Y is lower alkoxy, amino, lower alkylamino or ... | 06/06/1978 |
| 4089821 | Synthesis of peptide amides Peptide amides having biological activity and resin peptide amides useful in the preparation of peptides having biological activity, particularly such peptides containing the structure ##STR1## in which R is divinylbenzene crosslinked polystyrene and... | 05/16/1978 |
| 4086219 | Nonapeptides and methods for their production New nonapeptides having the formula Prot Grp-R-Trp-Ser-Tyr-R2 -Leu-Arg-Pro-Gly-R3 ; salts thereof; wherein R is Gln, Gln (bzl), His (bzl), Ser (bzl), Pro, Leu, Tyr (bzl), Ile, Cys (bzl) or Phe, R2 is D-Phe, D-Ala, D-Leu, D... | 04/25/1978 |
| 4075192 | Nonapeptides and methods for their production New nonapeptides having the formula pGlu-D-Phe-Trp-Tyr(benzyl)-Ser(benzyl)-D-Ala-Leu-Orn-Pro-Y and Y is amino, lower alkylamino or di(lower alkyl)amino.... | 02/21/1978 |
| 4046633 | Direct renin assay system and method An assay system and method for the direct determination of the enzymatic activity of the enzyme renin in a biological sample. An enzyme specific octopeptide is incorporated into substrate which is immobilized at one end on an insoluble carrier and is tagg... | 09/06/1977 |
| 4038282 | Pyridyl-4-methyl-succinimidocarbonate and process for its preparation The disclosed invention relates to &3xb5;-N-pyridyl-4-methyloxycarbonyllysine valuable in the synthesis of lysine containing peptides to the process of preparing this compound starting with 4-pyridyl-carbinol and succinimido-chloroformate and to the ... | 07/26/1977 |
| 4013791 | Peptides having an antihypertensive effect Novel peptide derivatives and a method of preparing the same are described. These compounds are useful in the diagnosis and treatment of hypertension.... | 03/22/1977 |
| 4010149 | Analogs of LH-RH and process for preparing the same Peptides having the formula N-Acetyl-N-methylglycyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Y-L-leucy l-L-arginyl-L-prolyl-Z wherein Y is a D--alkylglycine residue of the formula ##STR1## in which n is an integer of 0 through 3 inclusive and Z is ... | 03/01/1977 |
| 4008209 | Nonapeptide amide analogs of luteinizing releasing hormone The novel nonapeptide amide derivatives of the formula wherein R1 is Tyr or Phe; R2 is D-Leu, D-Ile, D-Nle, D-Val, D-NVa, D-Abu, -Aibu, D-Phe, D-Phg, D-Ser, D-Thr or D-Met; R3 is Leu, Ile or Nle and R4 is alky... | 02/15/1977 |
| 4001199 | Novel polypeptides useful for treating diabetes and hypercholesteremia Novel polypeptides of the formula wherein R1 is hydrogen, or a basic or neutral amino acid residue, R2 is a neutral amino acid residue and R3 is NH2, Tyr--NH2, a residue of tyrosyl peptides consisting of 1... | 01/04/1977 |
| 3998799 | Novel, transient pro-drug forms of L-DOPA There is provided, novel, transient pro-drug forms of L-DOPA (3,4-dihydroxy-L-phenylalanine), having the formula: ##STR1## wherein n represents an integer of from 2 to 50 with respect to formula (V-A), and wherein n represents an integer of from 1 to... | 12/21/1976 |
| 3992365 | Agonist analogues of luteinizing hormone releasing hormone Novel peptide compounds of the formula are provided together with their acid addition salts and their complexes with pharmaceutically acceptable metals. The compounds are LH-RH analogues and together with their salts and complexes exhibit LH-RH agonist ac... | 11/16/1976 |
| 3978035 | 13-Norleucine-14-desamido motilin, a method for preparing it and an agent containing it The specification describes the total synthesis of L-norleucine-13-motilin ased on the replacement of the L-methionine radical located in the 13-position by an L-norleucine radical. In accordance with the present day development of peptide synthesis the ce... | 08/31/1976 |
| 3975365 | Inhibitory octapeptides angiotensin II Octapeptide derivatives characterized by an oxygen or sulfur-containing moiety in the C-terminal position are potent inhibitors of the pharmacological effects of Angiotensin and possess the additional advantage of a favorable antagonist/agonist ratio.... | 08/17/1976 |
| 3974135 | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for producing the same A synthetic decapeptide, L-pglutamyl-L-histidyl-L-tryptophanyl-L-seryl-L-tyrosyl-glycyl-L-leucyl-L- arginyl-L-prolyl-glycinamide having the hormonal activity of the luteinizing hormone releasing hormone (LRH) of the hypothalamus gland of mammals is pr... | 08/10/1976 |
| 3972859 | Novel decapeptide amide analogs of leuteinizing hormone-releasing hormone The novel decapeptide amide derivatives of the formula wherein R1 is Tyr or Phe; R2 is D-Nle, D-Nva, D-Abu, D-Phe, D-Ser, D-Thr or D-Met and R3 is Leu, Ile or Nle have a strong ovulation inducing activity.... | 08/03/1976 |
| 3960828 | Catalytic hydrogenolysis of protected sulfur containing peptides The use of catalytic hydrogenolysis to selectively deblock protected moieties in sulfur containing compounds has not been a practical process due to poisoning of the catalyst by the sulfur compound. It has now been found that catalytic hydrogenolysis of s... | 06/01/1976 |
| 3953416 | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same A synthetic decapeptide, L-pglutamyl-L-histidyl-L-tryptophanyl-L-seryl-L-tyrosyl-glycyl-L-leucyl-L- arginyl-L-prolyl-glycinamide which has the hormonal activities of the luteinizing hormone releasing hormone (LRH) of the hypothalamus gland of mammals ... | 04/27/1976 |
| 3947575 | Peptides as argiotensin converting enzyme inhibitors Disclosed herein is a process for the utilization of certain peptides as angiotensin converting enzyme inhibitors.... | 03/30/1976 |
| 3937695 | P-Glu-Trp-Ser-Tyr-D-Lys-Leu-Arg-Pro-Gly-NH2 and intermediates D-Lys6 -des-His2 -LRF, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. The novel nonapeptide exhibits anti-ovulatory activity in mammals.... | 02/10/1976 |
| 3933782 | (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and intermediates (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. The novel non-apeptide exhibits and anti-ovulatory activity in mammals.... | 01/20/1976 |
