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| Number | Title | Issue Date |
| 7919572 | Polyamino acids functionalised with at least one hydrophobic group and applications thereof particularly therapeutic applications The invention relates to novel materials based on biodegradable polyamino acids, particularly useful for the vectorisation of active principals (PA). The invention further relates to novel, pharmaceutical, cosmetic, dietary or phytosanitary compositions. The inventi... | 04/05/2011 |
| 7759452 | Aspartic ester functional compounds A functional aspartate prepared by A) reacting an aziridine with a Michael-acceptor molecule to form an aziridinyl aspartate, and B) reacting the aziridinyl aspartate with an active hydrogen containing compound to form the functional aspartate. The functional aspart... | 07/20/2010 |
| 7396897 | N-α- and N-ε-lysine and ornithine compounds comprising a thiol function and cosmetic use thereof The present disclosure relates to the cosmetic use of poly-N-α- and -N-ε-lysine and ornithine compounds comprising a thiol function. The disclosure is also directed towards poly-N-α- and -N-ε-lysine and ornithine compounds comprising a thiol function and also to... | 07/08/2008 |
| 7364879 | Stable biodegradable, high water absorbable polyglutamic acid hydrogel by 3-dimensional cross-linking and its preparation method The present invention relates to a method for the production of a stable biodegradable, high water absorbable γ-polyglutamic acid (γ-PGA) hydrogel by directly cross-linking (A) a γ-polyglutamic acid (γ-PGA), a γ-polyglutamate,... | 04/29/2008 |
| 7361644 | Specific antagonist for both E- and P-selectins Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 04/22/2008 |
| 7320951 | Silica-based drilling mud comprising glycoside lubricants with amino-linked alkyl chains The drilling mud with a lowered coefficient of friction having a silicate-based mud and a lubricant selected from the group consisting of: glycosides, alkylpolyalkoxyalcohols, alcohol ester polymers, amine phosphates, starch and combinations thereof. ... | 01/22/2008 |
| 7317070 | Process for the preparation of polyamino acids Among the various aspects of the present invention is an improved process for the preparation of polyamino acids generally, and more specifically, polyglutamic acid and polyaspartic acid. Another aspect is a process for the large scale (i.e. >1 kg) preparation of po... | 01/08/2008 |
| 7311980 | Polyactive/polylactic acid coatings for an implantable device A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ... | 12/25/2007 |
| 7307140 | Polyaspartimides The present invention relates to novel polyaspartimides, their method of production and the use of these polyaspartimides as reactive components for polyisocyanates in two-component polyurethane coating compositions. The polyaspartimides are prepared by reacting a p... | 12/11/2007 |
| 7303765 | Ultrafine-L-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same L-carnitine which has a particle size such that it substantially passes through a 100 USBS mesh sieve exhibits an increased bioavailability, a decreased hygroscopicity, and may be conveniently formulated with oil-based materials. ... | 12/04/2007 |
| 7279174 | Stent coatings comprising hydrophilic additives A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically... | 10/09/2007 |
| 7256251 | Methods of synthesis of polymers and copolymers from natural products Described are polymers and copolymers containing sorbitol, citric acid, starch, aspartic acid, succinic anhydride, adipic acid mixtures thereof, methods of their synthesis and their uses. ... | 08/14/2007 |
| 7253252 | Water-soluble aspartate The present invention relates to new water-soluble polyaspartic esters and also to their use in aqueous coating compositions. ... | 08/07/2007 |
| 7244443 | Polymers of fluorinated monomers and hydrophilic monomers A polymer of fluorinated monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains a polymer of fluorinated monomers and another biocompatible polymer. The polymer of fluorinated monomers or polymer blend described herein and o... | 07/17/2007 |
| 7241495 | Polyhydroxyalkanoic acid fibers with high strength, fibers with high strength and high modulus of elasticity, and processes for producing the same The present invention is a process for producing a fiber, comprising: melt-extruding polyhydroxyalkanoic acid; solidifying the polyhydroxyalkanoic acid by quenching it to its glass transition temperature +15° C. or less, to form an amorphous fiber; cold-drawing the... | 07/10/2007 |
| 7230068 | Polymer derivatives The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorp... | 06/12/2007 |
| 7172817 | Indium particle containing tin, method for producing the same and electroconductive sheet comprising the same An aqueous solution of a tin salt and an indium salt is added to an aqueous alkaline solution to form a hydroxide or a hydrate comprising tin and indium, the hydroxide or hydrate is heated at a temperature of 110 to 300° C. in the presence of water, filtered and dr... | 02/06/2007 |
| 7169453 | Multilayer structure and tank consisting of this structure, which has a barrier layer in direct contact with the fluid contained Described are structures comprising, successively: a first layer of high density polyethylene (HDPE), a layer of binder, a second layer of EVOH or of a mixture based on EVOH, optionally a third layer of polyamide (A) or of a mixture of polyamide (A) and polyolefin (... | 01/30/2007 |
| 7163915 | Aqueous solutions containing dithionic acid and/or metal dithionate for metal finishing This invention relates to solutions of dithionic acid and/or dithionate salts which use in metal finishing processes such those used for the cleaning, activating, electroplating, electroless plating, conversion coating and/or other pre-treatment or post-treatment of... | 01/16/2007 |
| 7144978 | Multidrop tree branching functional polyethylene glycol, methods of preparing and using same Multi-armed functional polyethylene glycol polymers with active terminal groups may be used in conjugation with small molecule pharmaceuticals, proteins and peptides to enhance half-life and bioavailability of the drug and improve solubility, stability and immunolog... | 12/05/2006 |
| 7098361 | Rigid ring amino acids and polyamides there from This invention is a family of α,ω amino acids based on 1,4 substituted rigid ring structures and the useful polyamides made from them. ... | 08/29/2006 |
| 7094256 | Coatings for implantable medical device containing polycationic peptides Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coatings include carboxylated acrylates and polycationic peptides, for example R7. ... | 08/22/2006 |
| 7091305 | Copolymers of amino acids and methods of their production Disclosed are copolymers based on aspartic acid or its precursor molecules and methods of their production. The copolymers are water-soluble over a wide range of composition and molecular weight. Their preparation involves conversion of a polysuccinimide to copolyme... | 08/15/2006 |
| 7091306 | Process for preparing polyalkenylsuccinimides The present invention relates to an improved process for preparing polyalkenylsuccinimides having a sediment level less than 0.1 vol % comprising the steps of: (a) preparing a polyalkenyl derivative of an unsaturated acidic reagent... | 08/15/2006 |
| 7084097 | Cleaning solution for substrates of electronic materials The present invention relates to a cleaning solution capable of removing efficiently at the same time particles and metallic impurities from a substrate surface without corroding metallic materials. The cleaning solution for cleaning substrates of electronic ... | 08/01/2006 |
| 7078475 | Synergistic amine chain-extenders in polyurea spray elastomers Disclosed are derivatives of isophorone diamine exhibiting a synergistic relationship with other commonly employed chain extenders offering enhanced efficacy with regard to slowing of the polyurea elastomer cure profile, and processes employing their use. According ... | 07/18/2006 |
| 7074881 | Methods of synthesis of polysuccinimide, copolymers of polysuccinimide and derivatives thereof Disclosed are methods of synthesis of copoly(succinimide-aspartate), copolymers and derivatives thereof, prepared in a thermal or supercritical fluid method. Also disclosed are methods of isolating, compounding, stabilizing and processing the copoly(succinimide-aspa... | 07/11/2006 |
| 7074968 | Continuous process for the preparation of polytrimethylene ether glycol The invention is a continuous process for the preparation of polytrimethylene ether glycol from 1,3-propanediol reactant. In addition, the invention is directed to a continuous multi-stage process comprising reacting at least one reactant in a liquid phase in an up-... | 07/11/2006 |
| 7070798 | Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine A coating for an implantable medical device is disclosed. The coating comprises a polymer and an amino acid chemically bonded, attached or conjugated to the polymer. In one embodiment, the coating can include a therapeutic substance. In lieu of bonding the amino aci... | 07/04/2006 |
| 7060685 | Compounds and methods for inhibiting selectin-mediated function Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 06/13/2006 |
| 7056523 | Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine An implantable medical device, such as a stent, is disclosed comprising an amino acid or a polypeptide bonded to a plasma polymerized film layer formed on the device. A method of manufacturing the same is also disclosed. ... | 06/06/2006 |
| 7053170 | Preparation of high molecular weight polysuccinimides Described are methods of production of polysuccinimides having molecular weights up to 200,000 daltons and higher. The polysuccinimides of the invention are essentially unbranched and uncrosslinked. They can be modified by crosslinking, ring-opening, and/or other fu... | 05/30/2006 |
| 7033602 | Polycationic peptide coatings and methods of coating implantable medical devices Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed. ... | 04/25/2006 |
| 7030208 | Biocompatible materials and probes The present invention relates to fluorinated biopolymer and polymer derivatives useful as imaging probes, diagnostic agents and contrast agents and to imaging methods employing the fluorinated biopolymers and polymers. ... | 04/18/2006 |
| 7018567 | Antistatic flame retardant resin composition and methods for manufacture thereof An antistatic flame retardant composition comprises a polycarbonate resin; an impact modifier comprising polysiloxane; an antistatic agent; and a flame retardant in a an amount greater than or equal to about 9 wt % of the total composition. Owing to its excellent an... | 03/28/2006 |
| 7011842 | Polycationic peptide coatings and methods of making the same Polycationic peptide coatings for implantable medical devices and methods of making the same are described. The methods include applying an emulsion on the device, the emulsion including a polymer and a polycationic peptide. Other methods include incorporation of th... | 03/14/2006 |
| 7005123 | Functional poly-α-amino-acid derivatives useful for the modification of biologically active materials and their application A linear poly-α-amino-acid derivative has at least glutamic or aspartic or serinic repeating units and additionally having a functional group at one or both ends of the polymer backbone and/or only a single functional group as a side group on the polymer backbone, ... | 02/28/2006 |
| 6994867 | Biocompatible carrier containing L-arginine L-arginine conjugated to a polymeric matrix is disclosed. The matrix can be used as, for example, a coating for an implantable medical device such as a stent. ... | 02/07/2006 |
| 6976537 | Method for decreasing lost circulation during well operation A method is provided for reducing lost circulation when aqueous, oil, or synthetic based drilling fluid is used. The method includes injecting two fluids into the well bore and lost circulation zone. The first fluid is an aqueous liquid containing at least one polym... | 12/20/2005 |
| 6964998 | Water-absorbing agent and its production process and use The present invention provides: a water-absorbing agent which has excellent urine resistance; a water-absorbing agent which has not only excellent urine resistance, but also excellent absorption properties that are stable to any composition of urine and show little ... | 11/15/2005 |