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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8022155 | Polymerized molded body The invention relates to polymerizable compositions which comprise 10-80% by weight of a reactive diluent based on acrylic acid or methacrylic acid derivatives, and 10-50% by weight of a monomer of the indicated chemical formula which is liquid or which can be disso... | 09/20/2011 |
| 7192478 | Fatty (meth) acrylates and their use in dispersing pigments Fatty (meth)acrylates having a %-EpO content of below 0.6, which are reaction products of epoxidized compounds selected from the group consisting of epoxidized fatty acid esters, epoxidized triglycerides and mixtures thereof, and acids selected from the group consis... | 03/20/2007 |
| 7172678 | Process of making composite sheet material A composite sheet material, useful as a component of roofing shingles, and a process of making same, which includes a glass fiber web bound with a thermosetting resin which includes a fatty acid amide having the structural formula RCOONH2, where R is a C | 02/06/2007 |
| 7053043 | Pharmaceutical compositions comprising synthetic peptide copolymers and methods for preventing and treating GVHD and HVGD Compositions and methods for treating and preventing host-versus-graft disease and graft-versus-host disease comprising as active ingredient random copolymers of amino acids comprising one amino acid from at least three of the following groups: (a) lysine and argini... | 05/30/2006 |
| 7005136 | Bone replacement materials utilizing bioabsorbable liquid polymers The present invention is directed to bone replacement devices and compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer h... | 02/28/2006 |
| 6977285 | Oligomers containing N-acetyl glucosamine (NAG) Functional polyvalent oligomer for applications in medicine and biotechnology are disclosed. These oligomers have the formula (1) wherein R is H, CH3, C2H5, R1, is H, NH2, OH, COOH, X is... | 12/20/2005 |
| 6884842 | Molecular compounds having complementary surfaces to targets Synthetic polymer complements (SPCs) are provided, as well as methods for their synthesis and use. The SPCs may have surfaces that include functional groups that are complementary to surface sites of targets such as nanostructures or macromolecular targets, and may ... | 04/26/2005 |
| 6709734 | Resin sheet, thermoformed article, and multilayer structure Disclosed are a resin sheet that has a resin layer which is made up of a thermoplastic resin and which has a degree of orientation of not less than 0.0002 and not more than 0.0020, and a thermoformed article and laminate structure. The resin sheet is preferably empl... | 03/23/2004 |
| 6548601 | Fast-dry high solids coatings based on modified alkyd resins An ambient oxidative cure composition based on an acrylate functionalized alkyd resin is described. A method of preparing an ambient oxidative cure composition based on an acrylate functionalized alkyd resin is also described. Such ambient oxidative cure ... | 04/15/2003 |
| 6525154 | Molecular imprinting for the recognition of peptides in aqueous solution Molecularly imprinted polymers (MIPs) wherein the template comprises either a) a peptide or amino acid sequence that has an N-terminal histidine residue or b) histamine. The MIP's may be prepared in aqueous systems using reagents that are water soluble at... | 02/25/2003 |
| 6489418 | Preparation and application of artificial anti-idiotypic imprints This patent application describes the use of molecular imprinting as a means for preparation of anti-idiotypic imprint matrices. With this technique, imprints of artificial or natural molecules including their recognition sites, such as of molecularly imp... | 12/03/2002 |
| 6372813 | Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays The present invention provides solid supports (e.g., glass) and polymer hydrogels (particularly polymer hydrogel arrays present on a solid support) comprising one or more reactive sites for the attachment of biomolecules, as well as biomolecules comprisin... | 04/16/2002 |
| 6291616 | Methods and reagents for capping ruthenium or osmium carbene-catalyzed ROMP products Methods of preparing a telechelic polymer (mono- or bi-telechelic) that use a ruthenium or osmium carbene catalyst and a capping agent, at least one of which is functionalized.... | 09/18/2001 |
| 6121398 | High modulus polymers and composites from plant oils The synthesis of liquid molding resins derived from plant oils that are capable of curing to high modulus thermosetting polymers and composites is described in this invention. The resins described resemble the unsaturated polyester, vinyl ester and epoxy ... | 09/19/2000 |
| 6046289 | Propenamide derivatives containing Arg-Gly-Asp polymers obtained therefrom A propenamide derivative of the formula (I) having, as an essential structural unit, an adhesive peptide represented by the formula (II) in the side chain or salts thereof: Formula (I): R1 R2 C.dbd.CR3 --CO--[NH]-- Formula (II)... | 04/04/2000 |
| 5945457 | Process for preparing biologically compatible polymers and their use in medical devices A hemocompatible composition comprising a polymer containing at least one pharmacologic material chemically bonded to a polymer backbone. Such compositions may be obtained by reacting a pharmacologic material with a compound containing a polymerizable gro... | 08/31/1999 |
| 5858296 | Preparation of biologically active molecules by molecular imprinting A method for preparing mimics of a wide variety of drugs and other biologlly active molecules using molecular imprinting techniques, and the mimics produced thereby, is disclosed. Specifically, the mimic is designed by: (i) polymerization of functional m... | 01/12/1999 |
| 5807942 | Polymerized product of protein and process for producing it A polymerized product of protein, comprising a polymer of one or more protein-containing monomers represented by the general formula Pr --(Y)k --(X)m --R1 !n (1) wherein R1 represents a pol... | 09/15/1998 |
| 5733538 | Surface-modifying copolymers having cell adhesion properties A hemocompatible surface-modifying additive is provided for modifying polyurethane or polyurethane urea substrates. The additive has a polyurethane or polyurethane urea hard block or an alternative block which is miscible with the poly(urethane) or poly(u... | 03/31/1998 |
| 5630978 | Preparation of biologically active molecules by molecular imprinting A method for preparing mimics of a wide variety of drugs and other biologically active molecules using molecular imprinting techniques, and the mimics produced thereby, is disclosed. Specifically, the mimic is designed by: (i) polymerization of functional... | 05/20/1997 |
| 5516864 | Fluorescent ion-selective diaryldiaza crown ether conjugates This invention describes novel sensors for ions that are based on the combination of xanthylium-based dyes with metal-binding N,N'-diaryldiaza crown ethers. These sensors are primarily useful for detection and quantitation of alkali-metal ions in aqueous ... | 05/14/1996 |
| 5482996 | Protein-containing polymers and a method of synthesis of protein-containing polymers in organic solvents The present invention provides protein-containing polymers and a general method of incorporating biologically active proteins into a polymer matrix via copolymerization in organic solvents. Preferably, the protein is an active enzyme which maintains its a... | 01/09/1996 |
| 5446078 | Biodegradable compositions produced by reactive blending of synthetic and naturally occurring polymers A biodegradable interpolymer and composition is prepared by the reactive blending of a synthetic polymer having functional groups with a naturally occurring biodegradable polymer such as a carbohydrate or protein compound. During reactive blending, the sy... | 08/29/1995 |
| 5373052 | Organic polymer microparticle and process for producing the same Disclosed is an organic polymer microparticle which is obtainable from copolymerization of (a) an ethylenically unsaturated amine polymer obtained by reacting an amine polymer having at least two primary amino groups with 0.01 to 0.99 molar equivalents ba... | 12/13/1994 |
| 5357001 | Optically active amino acid sulphoxide and amino acid sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatographic resolution of racemates The invention relates to new optically active amino acid derivatives of the general formula (I) ##STR1## in which n, R, R1, R2, R3, X and A have the meaning given in the description, which amino acid derivatives conta... | 10/18/1994 |
| 5286829 | Biocompatible polymer material and a process for producing same A biocompatible material which is the product of graft-copolymerization of a water-soluble vinyl and/or an acrylate monomer with a sorption complex of polysilicic acid and collagen that has been rid of pigments, glycoproteins and proteoglycans, or a produ... | 02/15/1994 |
| 5198531 | Polymeric resin for peptide synthesis A polymeric resin for the preparation of peptides utilizing a polymeric matrix such as polystyrene-divinylbenzene copolymer. A vanillyl alcohol (HMBA), Trityl alcohol, or Trityl Amine group is attached to the polymeric carrier for use in the building poly... | 03/30/1993 |
| 5187207 | Melanin hydrophilic contact lenses A hydrophilic contact lens is disclsoed incorporating melanin that protects the eye from harmful radiation and superoxide.... | 02/16/1993 |
| 5112883 | Medium incorporating melanin as an absorbing pigment against electromagnetic radiation The present invention is directed to a medium incorporating melanin for radiation protection.... | 05/12/1992 |
| 5047447 | Medium incorporating melanin as an absorbing pigment for protection against electromagnetic radiation The present invention is directed to a medium incorporating melanin for radiation protection.... | 09/10/1991 |
| 5037883 | Synthetic polymeric drugs A polymeric drug comprising an inert synthetic polymeric carrier combined through aminoacid or peptide spacers with a bioactive molecule, a targeting moiety, and an optional cross-linkage, comprises: (a) 5.0 to 99.7 mol % of units derived from N-(2-hydrox... | 08/06/1991 |
| 5036115 | Optical lens system incorporating melanin as an absorbing pigment for protection against electromagnetic radiation Melanin is used as the absorbing pigment for radiation protective eyeware. Thus, a melanin-plastic copolymer was formed by adding a catalyst (benzoyl peroxide) to the liquid monomer, diethylene glycol bis allyl carbonate (CR-39), which contained dissolved... | 07/30/1991 |
| 5034428 | Immobilized biomolecules and method of making same A method of biomolecule immobilization is described in which the biomolecule itself or, alternatively, a monomer-conjugated biomolecule, is grafted with free monomer onto a hydrophilic, solid-phase, polymeric substrate which has been pre-irradiated with i... | 07/23/1991 |
| 4859753 | Branched lipopeptide polymers forming thermotropic and lyotropic liquid crystals, their applications and corresponding monomers Branched polymers resulting from homopolymerization or copolymerization of monomers of formula I: ##STR1## R is H or a lower alkyl group of C1 to C3 ; Z is O or NH; B has the formula: in which q1 and q2 are... | 08/22/1989 |
| 4843010 | Polymerization-induced separation immunoassays Immunoassay methods and compositions are disclosed for the detection of analytes in fluid samples. The disclosure provides conjugates of analytes or reactants with polymerizable organic monomers. Specific binding reactions between reactants are detected b... | 06/27/1989 |
| 4829098 | Immobilized biomolecules and method of making same A method of biomolecule immobilization is described in which the biomolecule itself or, alternatively, a monomer-conjugated biomolecule, is grafted with free monomer onto a hydrophilic, solid-phase, polymeric substrate which has been pre-irradiated with i... | 05/09/1989 |
| 4752638 | Synthesis and use of polymers containing integral binding-pair members Conjugate monomers, polymers, and methods for the de novo synthesis of the polymers are provided. Conjugate organic monomers contain binding-pair members which upon polymerization become integrally associated with the resultant polymer. Specifically, anti... | 06/21/1988 |
| 4749647 | Polymerization-induced separation assay using recognition pairs Methods and compounds are disclosed for determining the presence, amount of, or association between substances of interest in samples suspected of containing same. The methods are based on the polymerization-induced separation of specifically-bound, repor... | 06/07/1988 |
| 4711840 | Polymerization-induced separation immunoassays Immunoassay methods and compositions are disclosed for the detection of one or more analytes in fluid samples. The disclosure provides conjugates of analytes or reactants with polymerizable organic monomers. Specific binding reactions between reactants ar... | 12/08/1987 |
| 4698374 | Optical lens system incorporating melanin as an absorbing pigment for protection against electromagnetic radiation The present invention is directed to optical lens systems for radiation protection of the human eye utilizing melanin as an absorbing pigment.... | 10/06/1987 |
