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| Number | Title | Issue Date |
| 7683106 | Primer for dental materials and pulp capping agent for dentin regeneration A dental material primer and a dentin-regenerating pulp-capping agent which exhibit an excellent dentin-regenerating action, are disclosed. The dental material primer includes a hydrolyzed ethylene-vinyl acetate copolymer in which collagen is immobilized and the den... | 03/23/2010 |
| 7393493 | Crosslinkable polymeric materials and their applications The present invention relates to a novel composition for dental, orthopedic and drug delivery purpose. Specifically, it relates to composition comprising an admixture of a resorbable bone substitute and a crosslinkable prepolymer. It also relates to the composition ... | 07/01/2008 |
| 7365106 | Cationically curable composition for dental use A cationically curable composition for dental use containing a cationic polymerization initiator (I) and cationically polymerizable monomers (II), the cationically polymerizable monomers (II) containing an oxetane compound and an epoxy compound or an alkenyl ether c... | 04/29/2008 |
| 7341601 | Woven orthopedic implants The present invention relates to orthopedic implants made from a mesh material. The mesh material can be treated in order to promote bone growth, to provide antibiotics, or to provide other beneficial treatment. Specific applications for the implants include, for ex... | 03/11/2008 |
| 7300662 | Drug/drug delivery systems for the prevention and treatment of vascular disease A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f... | 11/27/2007 |
| 7241486 | Bone grafting materials The present invention relates to porous bone filling materials prepared by sintering bioactive glass fibers in order to achieve a three dimensional block with interconnecting porosity. Due to the osteoconductive properties the bioactive glass fibers, in block form a... | 07/10/2007 |
| 7238203 | Bioactive spinal implants and method of manufacture thereof A bioactive spinal implant used in cervical fusion, Anterior Lumbar Interbody Fusion (ALIF), Posterior Lumbar Interbody Fusion (PLIF), and Transforaminal Interbody Fusion (TLIF), having properties and geometries that enhance bone contact, stability, and fusion betwe... | 07/03/2007 |
| 7232852 | Photopolymerizable compositions that include alicyclic/aromatic dioxiranes and novel dioxiranyl tetraoxaspiro [5.5] undecanes A visible light cationically photopolymerizable composition is provided. This composition includes an expanding monomer and a dioxirane. More specifically, the expanding monomer used in this composition is one or more dioxiranyl tetraoxaspiro[5.5]undecanes. The comp... | 06/19/2007 |
| 7230039 | Bioactive nanocomposites and methods for their use Orthopedic compositions are provided that include a homogeneous mixture of a biocompatible polymer and a bioactive particulate ceramic wherein the ceramic has an average particle size of not more than 500 nm are provided. The compositions may be used to form bone ce... | 06/12/2007 |
| 7229473 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 06/12/2007 |
| 7223286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/29/2007 |
| 7217286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/15/2007 |
| 7186759 | Biologically active material The invention relates to a heterophasic composition which essentially consists of three immniscible components, A, B and C, and the production method of the same. The component A is some body compatible polymer, the component H is a water soluble or hydrolytically d... | 03/06/2007 |
| 7163691 | Bone graft An improved demineralized bone matrix (DBM) or other matrix composition is provided that has been mixed with a stabilizing agent that acts as (1) a diffusion barrier, (2) a enzyme inhibitor, (3) a competitive substrate, or (4) a masking moiety. A diffusion barrier a... | 01/16/2007 |
| 7148267 | Dye composition for the individual dying of prostheses plastics Kit for the preparation of dental prostheses which contains (i) polymerizable matrix material, (ii) filler and (iii) at least one dye composition in physically separate form. ... | 12/12/2006 |
| 7144414 | Surgical procedures and instruments Surgical instruments and methods are provided. In one aspect, a method of securing a fixation device within an opening in a tissue is provided, including delivering a material in a flowable state to said opening, and changing the state of the material so that the ma... | 12/05/2006 |
| 7141520 | Antimicrobial alkali-silicate glass ceramic and the use thereof The invention relates to a glass ceramic, wherein the initial glass comprises 30–65 percent (by weight) SiO2; 5–30 percent (by weight) Na2O; 5–30 percent (by weight) CaO, and 0-15 percent (by weight) P2O5, and wherei... | 11/28/2006 |
| 7060287 | Tissue augmentation material and method A permanent, biocompatible material for soft tissue augmentation. The biocompatible material comprises a matrix of smooth, round, finely divided, substantially spherical particles of a biocompatible ceramic material, close to or in contact with each other, which pro... | 06/13/2006 |
| 7052517 | Delivery device for biological composites and method of preparation thereof An apparatus for the delivery of a biological composite and a method, kit, and system for preparing a biological composite is described herein. The biological composite includes both inorganic and biological materials. ... | 05/30/2006 |
| 7026374 | Injectable microdispersions for medical applications The present invention is directed to microdispersions and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid po... | 04/11/2006 |
| 6987136 | Bioactive spinal implant material and method of manufacture thereof Bioactive spinal implant materials having optimized radiopacity, stiffness, and bioactivity properties for formulation of shaped bodies capable of withstanding large dynamic, compressive loads are provided. The invention also provides methods of making the optimized... | 01/17/2006 |
| 6936271 | Collagenous tissue compositions Implant compositions are disclosed consisting of a biocompatible carrier medium such as a saline or dextran solution and particles of collagenous material dispersed therein. The collagenous material is derived from tissue which has been milled to provide fragments o... | 08/30/2005 |
| 6926903 | Resorbable polymer composition, implant and method of making implant Novel polymer compositions that are useful in the manufacture of medical implants, implants having osteogenic properties and methods of making said implants are disclosed. Polymer compositions comprise a base material including a polymer matrix of resorbable polymer... | 08/09/2005 |
| 6913764 | Antibiotic(s) preparation with retarding active ingredient release The present invention concerns an antibiotic/antibiotics preparation for resorbable and non-resorbable implants for human and veterinary medicine, for the treatment of local microbial infections in hard and soft tissue. The invented antibiotic/antibiotics preparatio... | 07/05/2005 |
| 6867240 | Porous composite materials Methods and compositions are described that provide three dimensional porous matrices as structural templates for cells. The porous matrices of the present invention have desirable mechanical properties suitable to a variety of applications, including platforms for ... | 03/15/2005 |
| 6863900 | Regeneration and augmentation of bone using mesenchymal stem cells Disclosed are compositions and methods for augmenting bone formation by administering isolated human mesenchymal stem cells (hMSCs) with a ceramic material or matrix or by administering hMSCs; fresh, whole marrow; or combinations thereof in a resorbable biopolymer w... | 03/08/2005 |
| 6770695 | Time release calcium sulfate matrix for bone augmentation An implant composition having controlled resorption rate in vivo for stimulating bone growth, a method of making the implant composition, and a kit of implant materials are disclosed. The implant composition includes a calcium sulfate compound, polymer containing pa... | 08/03/2004 |
| 6770289 | Liquid pharmaceutical composition for treating bone diseases The invention provides a liquid pharmaceutical composition and methods for use in the treating of bone diseases, the composition being an aqueous solution comprising 0.05% to 35% by weight of ibandronaic acid or salts thereof; 0.1% to 5% by weight of a pH regulating... | 08/03/2004 |
| 6730156 | Clustered particle dental fillers A filler comprising a substantially amorphous cluster comprising non-heavy metal oxide particles and heavy metal oxide. The filler can be mixed into a hardenable resin to provide radiopaque dental materials having desirable strength and aesthetic character. ... | 05/04/2004 |
| 6638069 | Shaping cap for dental pin structures Shaping cap made of ceramic, metal or plastic material, which is suitable as a solid constituent of dental pin structures.... | 10/28/2003 |
| 6599518 | Solvent dehydrated microbially-derived cellulose for in vivo implantation A solvent dehydrated microbially-derived cellulose material is described for use as an implantable material in general and plastic surgery.... | 07/29/2003 |
| 6593394 | Bioactive and osteoporotic bone cement A composition for use as a bioactive bone cement having a powder component including strontium-containing hydroxy apatite and formulated to create a settable fluid substance when mixed with a liquid component. The liquid component includes a Bisphenol A d... | 07/15/2003 |
| 6555123 | Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation Polyhydroxyalkanoate materials are provided which are suitable for repair of soft tissue, augmentation, and as viscosupplements in animals, particularly humans. The materials comprise liquid polyhydroxyalkanoate polymer compositions or polyhydroxyalkanoat... | 04/29/2003 |
| 6541024 | Regeneration and augmentation of bone using mesenchymal stem cells Disclosed are compositions and methods for augmenting bone formation by administering isolated human mesenchymal stem cells (hMSCs) with a ceramic material or matrix or by administering hMSCs; fresh, whole marrow; or combinations thereof in a resorbable b... | 04/01/2003 |
| 6482427 | Compositions and methods for repair of osseous defects and accelerated wound healing Compositions useful for repairing osseous defects and healing of wounds and burns include particulate bioactive and biocompatible glass including 40 to 58% by weight silica, 10 to 32% by weight calcia, 10 to 32% by weight soda, 2 to 10% by weight phosphor... | 11/19/2002 |
| 6479565 | Bioactive ceramic cement The present invention provides a solution to the problems with known cements by providing a composition comprising (a) microscopic anhydrous pellets or particles containing the most important components of biological fluids or synthetic biological fluids ... | 11/12/2002 |
| 6432437 | Soft tissue augmentation material A permanent, biocompatible material for soft tissue augmentation. The biocompatible material comprises a matrix of smooth, round, finely divided, substantially spherical particles of a biocompatible ceramic material, close to or in contact with each other... | 08/13/2002 |
| 6428803 | Hydroxylapatite gel The invention relations to a hydroxylapatite gel obtained through a sol-gel process, in which an alkaline aqueous solution of a calcium salt is reacted with an alkaline aqueous solution of a phosphate salt in a calcium and phosphorous molar ratio in the r... | 08/06/2002 |
| 6417247 | Polymer/ceramic composites The present invention provides a composition which comprises a polymer or polymer solution that forms a gel under controlled parameters and a ceramic matrix, the composition being fluid under non-physiological conditions and non fluid under physiological ... | 07/09/2002 |
| 6403671 | Polymerizable composition and the application thereof as a coupling agent The invention relates to a polymerizable, cross-linkable composition which contains: (A) 1-99.99 wt.-% of at least one conversion product of OH-functional (meth)acrylates with (i) oligomers from unsaturated rings or heterocyclic rings and maleic anhydride... | 06/11/2002 |
