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| Number | Title | Issue Date |
| 7985783 | Aldehyde tags, uses thereof in site-specific protein modification The invention features compositions and methods for site-specific modification of proteins by incorporation of an aldehyde tag. Enzymatic modification at a sulfatase motif of the aldehyde tag through action of a formylglycine generating enzyme (FGE) generates a form... | 07/26/2011 |
| 7435763 | Solid freeform compositions, methods of application thereof, and systems for use thereof Compositions, methods of using the compositions, and solid freeform fabrication (SFF) systems for producing three-dimensional objects are disclosed. One exemplary composition, among others, includes a basic component, an acidic component, at least one monoacrylate c... | 10/14/2008 |
| 7413781 | Gels for encapsulation of biological materials This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as... | 08/19/2008 |
| 7393493 | Crosslinkable polymeric materials and their applications The present invention relates to a novel composition for dental, orthopedic and drug delivery purpose. Specifically, it relates to composition comprising an admixture of a resorbable bone substitute and a crosslinkable prepolymer. It also relates to the composition ... | 07/01/2008 |
| 7288319 | Forming a chemically cross-linked particle of a desired shape and diameter Chemically cross-linked polymeric particles are formed using mechanical rather than chemical processes, facilitating production of small-diameter particles in a manner largely independent of the viscosity or density of the polymer. For example, an uncross-linked res... | 10/30/2007 |
| 7273896 | Compositions and methods of using a transient colorant This invention relates generally to compositions and systems for forming biomaterials containing a transient colorant for visualizing tissue or surgical materials coated with such biomaterials, to methods of using such compositions as bioadhesives, for tissue augmen... | 09/25/2007 |
| 7252981 | Method for the preparation of stable and reusable biosensing granules The present invention provides a process for the preparation of stable and reusable biosensing granules useful in the assessment of biodegradability of effluents. The biosensing granules are prepared by culturing active aerobic microbial consortia in synthetic mediu... | 08/07/2007 |
| 7192984 | Compositions of polyacids and polyethers and methods for their use as dermal fillers The present invention relates to improved methods for filling the skin for cosmetic or medical purposes. Compositions comprising carboxymethyl cellulose (CMC), polyethylene oxide (PEO) and calcium ions can be made and have physical properties that depend on the amou... | 03/20/2007 |
| 7183336 | Irradiated absorbent materials Polymer particles are irradiated with radiation from a high energy source to increase the water or other fluid absorbency of the particles. Products manufactured using the activated particles include protective undergarments, bandages, kitty litter, and spill clean ... | 02/27/2007 |
| 7141302 | Suture material for surgery, processes for its production and the use thereof A suture material for surgery comprises one or more filaments and is formed with a coating, which is characterized in that the coating at least partly comprises a bioresorbable polymer, which is essentially formed from a random terpolymer with a completely amorphous... | 11/28/2006 |
| 7053134 | Forming a chemically cross-linked particle of a desired shape and diameter Chemically cross-linked polymeric particles are formed using mechanical rather than chemical processes, facilitating production of small-diameter particles in a manner largely independent of the viscosity or density of the polymer. For example, an uncross-linked res... | 05/30/2006 |
| 7049351 | Moldings and preparation and uses thereof An ophthalmic lens made from a crosslinkable polymer containing H-active groups bonded to the oligomer or polymer backbone, some or all of whose hydrogen atoms have been substituted by radicals of a N-hydroxyalkyl (meth)acrylamide. The lens transmits at least 70% of... | 05/23/2006 |
| 7045559 | Electrically conductive adhesive hydrogels with solubilizer A composition providing electrically conductive adhesive hydrogels suitable for use as skin contact adhesives and, particularly, suitable for use as an electrical interface for disposable medical devices. The present hydrogels provide for reduced skin irritation and... | 05/16/2006 |
| 7045366 | Photocrosslinked hydrogel blend surface coatings Hydrogel polymer blends including precursors and crosslinked forms of the compositions. The blends provide an improved approach to achieve high quality, uniform coatings with better commercial viability than other approaches including copolymerization. Applications ... | 05/16/2006 |
| 7029825 | Photosensitive resin compositive for printing plate precursor capable of laser engraving Disclosed is a photosensitive resin composition for forming a laser engravable printing element, comprising: (a) 100 parts by weight of a resin which is a plastomer at 20° C., wherein the resin has a number average molecular weight (Mn) of from 1,000 to 100,000 and... | 04/18/2006 |
| 7019043 | Decomposable resin composition and method for producing the same The invention provides a decomposable resin composition, which is stable at the time of use and which quickly decomposes when discarded. According to the present invention, there is provided a resin composition comprising an agent generating an acid or a base upon r... | 03/28/2006 |
| 7005508 | Nitroderivatives of polysaccharides The present invention provides a new class of compounds presenting a high compatibility with tissues and organic fluids. Such new compounds are polysaccharides essentially formed of units of uronic acid and/or hexosamine, containing nitro groups —ONO2 c... | 02/28/2006 |
| 6911227 | Gels for encapsulation of biological materials This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as... | 06/28/2005 |
| 6855746 | Process for the production of molded particles for enzyme- or microbial cell-immobilization This invention provides a process for the production of molded particles for enzyme- or microbial cell-immobilization which is characterized in that: an aqueous liquid composition which comprises: (A) an unsaturated group-containing ureth... | 02/15/2005 |
| 6841644 | Biopolymers obtained by solid state irradiation in an unsaturated gaseous atmosphere Disclosed are modified naturally occurring biocompatible biopolymers of plant and animal origin made by subjecting same to ionizing radiation in the presence of a mediating gas, typically acetylene to enable one to selectively enhance and modify one or more of the p... | 01/11/2005 |
| 6803392 | Photoinitiator formulations Aqueous storage-stable, non-sedimenting photoinitiator suspensions comprising (a) a mono- or bis-acylphosphine oxide of formula (I), wherein R1 is C1-C20alkyl; C2-C20alkyl interrupted by one or more O atoms; C | 10/12/2004 |
| 6723814 | Amphiphilic copolymer planar membranes Membranes made from amphiphilic copolymers are disclosed. The amphiphilic copolymers can be ABA copolymers, where one of A and B is hydrophilic and the other is hydrophobic. The copolymers may be crosslinked to form more stable structures. Crosslinking can be accomp... | 04/20/2004 |
| 6706778 | Process for the production of molded particles for microbial cell-immobilization This invention provides a process for the production of molded particles for microbial cell-immobilization which is characterized in that: an aqueous liquid composition which comprises: (a) an ethylenically unsaturated group-containing urethane resin w... | 03/16/2004 |
| 6610810 | Biopolymers obtained by solid state irradiation in an unsaturated gaseous atmosphere Disclosed is a method for modifying naturally occuring biocompatible biopolymers of plant and animal origin by subjecting same to ionizing radiation in the presence of a mediating gas, typically acetylene to enable one to selectively enhance and modify on... | 08/26/2003 |
| 6586493 | Polysaccharide-based hydrogels and pre-gel blends for the same Disclosed are hyaluronate-containing hydrogels having angiogenic and vascularizing activity and pre-gel blends for preparing the hydrogels. The hydrogels contain a cross-linked matrix of a non-angiogenic hyaluronate and a derivatized polysaccharide materi... | 07/01/2003 |
| 6515039 | Method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material The invention relates to a method for the parallel and combinatory synthesis of compounds bound to a continuous polymeric solid phase supporting material. According to the method, a continuous polymeric solid phase supporting material is prepared, the mat... | 02/04/2003 |
| 6403672 | Preparation and use of photopolymerized microparticles Methods of forming polymer particles in situ from polymer precursors such as monomers or oligomers, comprising exposing a composition comprising at least one polymer precursor, a solvent or solvent mixture, and an antisolvent or antisolvent mixture to pho... | 06/11/2002 |
| 6391939 | Collagenic material useful in particular for preventing post-operative adhesions The present invention relates to a biocompatible collagenous material which is non-toxic and biodegradable in less than one month, preferably in less than one week. This material comprises collagen and at least one hydrophilic macromolecular additive whic... | 05/21/2002 |
| 6306922 | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymeriz... | 10/23/2001 |
| 6254958 | Photosensitive resin composition and articles The present invention aims to develop a photosensitive resin composition which exhibits a rapid ink absorption rate, which has an excellent water resistance, and which is appropriate for providing an ink receiving layer forming a sharp ink dot shape and h... | 07/03/2001 |
| 6239190 | Enhancement of activation for `biological` tissue adhesives, bonding agents and sealants using "color change" chromophores There is disclosed a method for effecting a reaction by irradiating a substance which absorbs the radiant energy until the reaction is complete and the absorbency of the material changes so as to reduce or cease absorption of further radiant energy.... | 05/29/2001 |
| 6200733 | Photosensitive composition for sandblasting and photosensitive film comprising the same A photosensitive composition for sandblasting and a photosensitive film having a photosensitive layer comprising the photosensitive composition are disclosed, the photosensitive composition comprising a photopolymerizable urethane (meth)acrylate oligomer ... | 03/13/2001 |
| 6156345 | Crosslinkable macromers bearing initiator groups A crosslinkable macromer system that includes two or more polymer-pendent polymerizable groups and one or more polymer-pendent initiator groups. The polymerizable groups and the initiator group(s) can be pendent on the same or different polymeric backbone... | 12/05/2000 |
| 6031017 | Photocured cross-linked-hyaluronic acid gel and method of preparation thereof A photocured crosslinked-hyaluronic acid gel, which has a storage modulus (G') of from 50 to 1500 Pa, a loss modulus (G") of from 10 to 300 Pa, and a tangent delta (G"/G') of from 0.1 to 0.8 in dynamic viscoelasticity at a frequency of 10 Hz, and which is... | 02/29/2000 |
| 6007833 | Crosslinkable macromers bearing initiator groups A crosslinkable macromer system that includes two or more polymer-pendent polymerizable groups and one or more polymer-pendent initiator groups. The polymerizable groups and the initiator group(s) can be pendent on the same or different polymeric backbone... | 12/28/1999 |
| 5993796 | Biocompatible polymeric materials, methods of preparing such materials and uses thereof The present invention is directed to a biocompatible polymeric material and methods of making prepared by forming a mixture of collagen, a water-soluble ethylenically unsaturated compound and a cross-linking agent at a temperature of 30° C. to 42° C.; a... | 11/30/1999 |
| 5990191 | Granular carrier for immobilizing microbial cells and apparatus for producing the granular carrier A microorganism cells-immobilizing granular carrier and its manufacturing system. Said microorganism cells-immobilizing granular carrier, which has a specific gravity of 1.00 to 1.20, and which has a contact angle of 2° to 30° formed between the carrier... | 11/23/1999 |
| 5889075 | Irradiated surgical suture and method for making same A surgical suture fabricated from a copolymer containing dioxanone, trimethylene carbonate and glycolide is treated with gamma radiation to enhance bioabsorbability without adversely effecting handling properties.... | 03/30/1999 |
| 5846530 | Macrocapsules prepared from crosslinkable polysaccharides, polycations and/or lipids and uses therefor The present invention relates to a new form of biocompatible materials (e.g., lipids, polycations, polysaccharides) which are capable of undergoing free radical polymerization, e.g., by using certain sources of light; methods of modifying certain syntheti... | 12/08/1998 |
| 5837747 | Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release The present invention relates to a new form of biocompatible materials (e.g., lipids, polycations, polysaccharides) which are capable of undergoing free radical polymerization, e.g., by using certain sources of light; methods of modifying certain syntheti... | 11/17/1998 |
