...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 7427416 | Methods of treating conditions using metal-containing materials Methods of treating conditions using metal-containing materials are disclosed. Exemplary conditions include bacterial conditions, biofilm conditions, microbial conditions, inflammatory conditions, fungal conditions, viral conditions, autoimmune conditions, idiopathi... | 09/23/2008 |
| 7255881 | Metal-containing materials Metal-containing materials, as well as their preparation and use are disclosed. The metal-containing material can be, for example, an antimicrobial material, an anti-biofilm material, an antibacterial material, an anti-inflammatory material, an anti-fungal material,... | 08/14/2007 |
| 7235536 | Cellulose sulfate and other sulfated polysaccharides to prevent and treat papilloma virus infection and other infections The invention relates to the treating, inhibiting or preventing of certain infectious agents including papilloma virus and various vaginitis-causing microbes by employing cellulose sulfate and other sulfated polysaccharides. In one embodiment, the method involves pr... | 06/26/2007 |
| 7226622 | Chemoablation of tissue using biodegradable, solid salt dosage forms Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms i... | 06/05/2007 |
| 7087249 | Treatment of mucosal membranes The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and preferably in a nanocrystalline form, for reducing inflammation or infect... | 08/08/2006 |
| 6652874 | Pharmaceutical preparations and methods for their regional administration Formulations have been developed for regional delivery of drugs, for example, into a cavity such as the pelvic region, peritoneal region, or directly on organs of interest. Regional delivery increases comfort and bioavailability of the drug, resulting in ... | 11/25/2003 |
| 6329428 | Therapeutic drug for the treatment of micturition disorders The present invention is drawn to a therapeutic drug for micturition disorders and diseases of the lower urinary tract system, containing an organic acid salt of [2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]ethyl]-dimethylsulfonium. The invention... | 12/11/2001 |
| 6323211 | Compositions and methods for treating sexual dysfunctions The present invention describes methods for preventing and treating sexual dysfunctions in patients by orally administering at least one -adrenergic receptor antagonist and at least one compound that elevates endogenous nitric oxide or endothelium-... | 11/27/2001 |
| 6306900 | Enteric coated pharmaceutical compositions This invention provides a pharmaceutical composition comprising a mycophenolate salt, the composition being adapted to release mycophenolate in the upper part of the intestinal tract.... | 10/23/2001 |
| 6296847 | Composition for treating benign prostatic hypertrophy The invention provides a composition and method for treating benign prostatic hypertrophy in mammals so as to cause the dissolution and regression of hypertrophied prostatic tissue and thereby provide relief from the obstructive symptoms associated with t... | 10/02/2001 |
| 6294517 | Compositions and kits comprising alpha-adrenergic receptor antagonists and nitric oxide donors and methods of use The present invention describes novel compositions and kits comprising alpha-adrenergic receptor antagonists and compounds that donate, transfer or release nitric oxide, elevate endogenous levels of endothelium-derived relaxing factor, or stimulate nitric... | 09/25/2001 |
| 6290981 | Use of nitric oxide-releasing agents to treat impotency A method of treatment for impotency is provided. The method involves the administration of nitric oxide by a nitric oxide-releasing agent capable of providing a penile erection-inducing amount of nitric oxide to the corpus cavernosum of the penis of an im... | 09/18/2001 |
| 6270789 | Base for suppository The present invention provides a base for suppository comprising oily or fatty base and polyethlene. The suppository prepared by the use of the base of the present invention has superior heat resistance which should not cause quality deterioration such as... | 08/07/2001 |
| 6221401 | Bilayer structure which encapsulates multiple containment units and uses thereof The present invention provides a bilayer structure for encapsulating multiple containment units. These containment units can attach or contain therapeutic or diagnostic agents that can be released through the bilayer structure. A suitable example of such ... | 04/24/2001 |
| 6200557 | Method of treating HIV by a topical composition A solution or gel composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for destroying HIV. The pref... | 03/13/2001 |
| 6056966 | Method and compositions for treating impotence Pharmaceutical compositions in topical or parenteral form containing specific organic mono- or dinitrates, some of them novel compounds, are effective in treating male impotence and erectile dysfunction through topical or intracavernosal administration to... | 05/02/2000 |
| 6017554 | Composition for treating abnormal conditions of the epithelium of bodily orifices A stable solution cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for t... | 01/25/2000 |
| 5935592 | Method for treating vaginitis and endometriosis A stable solution, cream, salve, or spray composition containing activated chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for the treatme... | 08/10/1999 |
| 5902575 | Method for treating the epithelium of bodily orifices with chlorine dioxide and a phosphate compound A stable solution, cream, salve, or spray composition containing chlorine dioxide and a phosphate, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for the prevention and t... | 05/11/1999 |
| 5886039 | Method and composition for treating erectile dysfunction Lipophilic active substance composition and its use in a new method of treating erectile dysfunction by administration thereof, optionally together with a hydrophilic vehicle and optionally an antibacterial agent into the urethra.... | 03/23/1999 |
| 5834003 | Method for oxidatively consuming volatile sulfur compounds at bodily orifices A method for oxidatively consuming volatile sulfur compounds selected from the group consisting of dimethylsulfide, hydrogen sulfide, and methylmercaptan at the epithelial barrier of the rectal, vaginal, urethral, oral, nasal, ocular, and auditory canal o... | 11/10/1998 |
| 5820587 | Method and kit for preventing erectile dysfunction A method is provided for preventing erectile dysfunction, particularly vasculogenic impotence, in a male individual. The method involves periodic administration of a vasoactive agent throughout a 24-hour period. The agent and dosage regimen are selected s... | 10/13/1998 |
| 5811115 | Composition for treating abnormal conditions of the epithelium of bodily orifices A stable solution, cream, salve, or spray composition containing chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for the prevention and tr... | 09/22/1998 |
| 5667817 | Method and composition for prevention and treatment of female lower genital tract microbial infections Methods for preventing and treating microbial infections in the mammalian female lower genital tract such as vulvitis, vaginitis, cervicitis, and endometritis involve the intra-vaginal and/or intra-uterine infusion of a solution containing a pharmacologic... | 09/16/1997 |
| 5648101 | Drug delivery of nitric oxide A method of delivering NO gas to a desired situs on or in the body of a sentient animal, e.g. humans, comprising combining and causing to react a soluble reducing salt, preferably ferrous sulfate, and a nitrite, preferably sodium nitrite, as reactants in ... | 07/15/1997 |
| 5645830 | Lactobacillus and skim milk compositions and methods for preventing microbial urogenital infections This invention relates to Lactobacillus, skim milk, Lactobacillus Growth Factor (LGF) and Lactobacillus compositions and methods of employing the compositions for preventing urogenital infections. More particularly, this invention relates to the ability o... | 07/08/1997 |
| 5629012 | Process for producing suppositories by compression and suppositories obtained by the process Suppositories, produced by a process in which a suppository basic mass is produced containing (a) 50-75% of 5-aminosalicylic acid as an active ingredient, (b) 2-5% talc, magnesium stearate and/or polyvinyl pyrrolidone and (c) 20-48% by weight of a polyeth... | 05/13/1997 |
| 5618550 | Method for treatment of abnormal conditions of the epithelium of bodily orifices A stable solution, cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for ... | 04/08/1997 |
| 5599551 | Genital lubricants containing zinc as an anti-viral agent This invention relates to an article of manufacture comprising an aqueous gel containing a selected zinc salt contained within a deformable plastic-walled tubular container, for convenient and consistent use as a topical genital lubricant during acts of s... | 02/04/1997 |
| 5562899 | Medical prevention of lacerations to the vagina and perineum A common complication of vaginal delivery is the tearing of the muscles of the vagina and perineum. This tearing results in an irregular laceration which the surgeon must then repair. Current obstetrical practice is to prevent this irregular laceration by... | 10/08/1996 |
| 5545673 | Method for reducing risk of infection by sexually transmitted viruses A method is disclosed for reducing the risk of infection by sexually transmitted viruses. This method involves spreading a lubricant fluid containing a selected zinc salt across the surfaces of the penis or vagina, before intercourse, in a manner that cau... | 08/13/1996 |
| 5492911 | Linsidomine for the treatment for erectile dysfunctions The treatment of erectile dysfunctions in mammals, including humans, comprises administering to a host in need thereof an effective dose of linsidomine or a pharmacologically compatible salt thereof, alone or in combination with adenosine, vitamins, prost... | 02/20/1996 |
| 5489435 | Composition for treatment of abnormal conditions of the epithelium of bodily orifices A stable solution, cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for ... | 02/06/1996 |
| 5208031 | Sexual lubricants containing zinc as an anti-viral agent This invention relates to the use of zinc salts as anti-viral agents in sexual lubricants. A zinc salt which releases divalent zinc ions in an aqueous carrier fluid is provided in a sexual lubricant formulation which is spread on the genitals before sexua... | 05/04/1993 |
| 5204090 | Waterproof high-SPF sunscreen compositions Sunscreen compositions which are waterproof and have high-SPF values comprise a water insoluble film-forming polymer, a polyoxypropylene ether of straight or branched chain alcohol (the emollient/solvent) and a sunscreen component containing at least one ... | 04/20/1993 |
| 4997653 | Method for treating endometriosis with topical preparations containing danazol A topical preparation of danazol comprising a matrix base, danazol retained therein, and optionally a release-promoting agent is provided. The topical preparation is more effective than oral administration of danazol in the shrinkage of endometriosis tissue, t... | 03/05/1991 |
| 4962208 | Method for preparing time-stable solutions of non-pyrogenic magnesium gluconocitrates A method is improved for producing highly stable non-pyrogenic solutions of magnesium gluconocitrate. According to this process a specially prepared non-pyrogenic magnesium hydroxycarbonate or magnesium carbonate, gluconic acid anhydride and citric acid a... | 10/09/1990 |
| 4863900 | Method for reducing viral transmission with poly-L-histidine A composition for reducing the transmissability of viral infection from a subject infected therewith which comprises a topically applicable, pharmaceutically acceptable carrier and a viricidally effective amount of a polypeptide of between 24 and 500 amin... | 09/05/1989 |
| 4774329 | Controlled release agent for cetylpyridinium chloride A complex of cyclodextrin and cetylpyridinium chloride is disclosed as a controlled release agent of cetylpyridinium chloride. The cyclodextrin can be either cyclodextrin molecule, a polymer of cyclodextrin or modified cyclodextrin. The method of forming ... | 09/27/1988 |
| 4725576 | Fungicidal polypeptide compositions containing L-histidine and methods for use therefore Polypeptides containing a substantial proportion of L-histidine are effective fungicidal agents. They are particularly effective against C. albicans and have a high degree of safety and nontoxicity because of their structural similarity to naturally occur... | 02/16/1988 |