Famous Patents
3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 7666914 | Topical preparation and method for transdermal delivery and localization of therapeutic agents Disclosed herein is a preparation for topically delivering and localizing therapeutic agents, comprising: a vasoconstrictor for retarding vascular dispersion of a therapeutic agent; and a penetration enhancer for facilitating penetration of the vasoconstrictor and t... | 02/23/2010 |
| 7438926 | Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure This invention relates to a method for inhibiting a decrease in the transdermal flux of an agent that is being transdermally delivered or sampled over a prolonged period of time wherein the delivery or sampling involves disrupting at least the stratum corneum layer ... | 10/21/2008 |
| 7422756 | Skin preparation The invention concerns a skin preparation for moistening human skin comprising a combination of a component A and a component B, wherein A includes at least two saturated C9-C31 fatty acids selected from the group consisting of iso- and anteiso... | 09/09/2008 |
| 7374770 | Topical composition for follicular delivery of an ornithine decarboxylase inhibitor Polyethylene glycol ethers of alkyl alcohols having the general formula CH3(CH2)xCH2(OCH2CH2)nOH wherein x is 8 to 20 (of which ceteareth-20, steareth-20 and steareth-100 are preferred), po... | 05/20/2008 |
| 7326420 | Benzoyl peroxide compositions having increased potency A benzoyl peroxide composition having increased potency includes benzoyl peroxide, a tertiary amine and/or a transition metal, and a base that increases radicals formed by the peroxide. ... | 02/05/2008 |
| 7323185 | Methods of increasing the efficacy of peroxides This invention relates to methods of increasing the efficacy of peroxides such as benzoyl peroxide in the treatment of skin conditions such as acne. In a preferred embodiment, the invention relates to methods of increasing radicals formed by peroxides on/in the skin... | 01/29/2008 |
| 7309497 | Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients The invention relates to novel pharmaceutical compositions for the systemic administration of pharmacologically active ingredients. The invention relates in particular to an injectable pharmaceutical composition comprising (a) a pharmacologically active ingredient i... | 12/18/2007 |
| 7270834 | Pharmaceutical composition comprising dimethylsulfoxide and ozone A pharmaceutical composition to be externally applied as a topical preparation for treating several diseases, the composition comprising dimethylsulfoxide (DMSO) and ozone. A method for obtaining the composition by ozonizing DMSO and a method for treating diseases b... | 09/18/2007 |
| 7267827 | Therapeutic compositions for intranasal administration which include KETOROLAC An analgesic/anti-inflammatory pharmaceutical dosage form which comprises an effective amount of an active ingredient selected from the group consisting of racemic 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, optically active forms thereof and pharmaceuti... | 09/11/2007 |
| 7244447 | Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered nonsteroidal anti-inflammatory drugs (NSAIDs). The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase... | 07/17/2007 |
| 7241460 | Strontium compound for treatment of sub-dermal soft tissue pain The invention provides a method of treatment of a human or non-human subject to combat sub-dermal soft tissue pain therein, said method comprising administering to a subject in need thereof an effective amount of a physiologically tolerable strontium compound. ... | 07/10/2007 |
| 7235257 | Drugs for relieving hemicrania comprising 1-menthol and essential oils This invention relates to external drugs for dermal application which have a migraine-alleviating effect, in more detail ointments and patches comprising in mixing l-menthol and an essential oil into a base containing a hydrophilic high-molecular weight compound, a ... | 06/26/2007 |
| 7186706 | Administration of non-oral androgenic steroids to women The present invention provides compositions, methods, and kits for improving health in a woman having elevated SHBG levels, or who is receiving oral estrogen supplementation, by non-orally administering an effective amount of an androgenic steroid. Further, the pres... | 03/06/2007 |
| 7105571 | Prostaglandin compositions and methods of treatment for male erectile dysfunction The invention provides methods and compositions for treating erectile dysfunction. The methods include the step of placing within the fossa navicularis of the patient an effective erection-inducing amount of a vasoactive prostaglandin composition of a semi-solid con... | 09/12/2006 |
| 7094407 | Fusion peptide containing human type-1 collagen derived peptide, preparation thereof, and skin anti-aging cosmetic composition comprising the same The present invention relates to a fusion peptide, in which a self cell-penetrating Tat peptide having a self penetrating signal is bound to a human Type-I collagen C-terminal derived peptide, a preparation thereof, and a skin anti-aging cosmetic composition compris... | 08/22/2006 |
| 7081253 | Use of nanodispersions in pharmaceutical end formulations A description is given of the use of a nanodispersion, which comprises (a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component, in pharmaceutical end for... | 07/25/2006 |
| 7029659 | Mousse composition A topical mousse composition including an occlusive agent; an aqueous solvent; and an organic cosolvent, wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin. ... | 04/18/2006 |
| 7029663 | Stable ointment containing acetylsalicylic acid A substantially anhydrous stable ointment containing Aspirin which is characterized in using gelation hydrocarbon and/or vaseline as a base. The ointment is superior in stability and can be stored for a long term. ... | 04/18/2006 |
| 7025972 | Allergen absorbent, blocking, and deactivating compositions and method An allergen and blocking sorbent for topical application to the skin comprising a surface-modified layered material, such as an intercalated clay, dispersed in a cosmetically acceptable solvent. The organic surface modifier is an organic molecule that contains a sub... | 04/11/2006 |
| 6989152 | Compound for the amelioration of pseudofolliculitis A compound for reducing the incidence of pseudofolliculitis combines a mild skin astringent, an oil based epidermal softener, and a hair stiffener. One embodiment of the compound combines refined powdered oatmeal and emollient of the compound combines refined powder... | 01/24/2006 |
| 6979454 | Biologically active composition A biologically active stick composition comprising a biologically active agent dissolved in a carrier system including an unsaturated fatty acid alcohol in mutual dissolution with an alkylene glycol as a solvent for said biologically active agent and a stiffening ag... | 12/27/2005 |
| 6953590 | Tape material for transcutaneous absorption A preparation for transdermal absorption is disclosed which is suited for alleviating lasting pains caused by herpes zoster or postherpetic neuralgia and is practical and more improved in drug efficacy, safety and application characteristics. This tape preparation f... | 10/11/2005 |
| 6946120 | Pharmaceutical composition A pharmaceutical composition for topical administration, including, as the pharmaceutically active component, at least 5% by weight, based on the total weight of the composition of a piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; an a... | 09/20/2005 |
| 6929800 | Nasal passage cleaning composition A nasal passage cleaning composition according to the invention comprises water and salt as a base, and contains a mucolytic agent such as alum and/or zinc sulphate to shrink the mucosa and allow sinus passage drainage, decreasing pressure in the infected sinus an a... | 08/16/2005 |
| 6878365 | Topical application for treating toenail fungus A topical applications is used to treat and prevent the spread of nail infections or onychomycosis caused by bacteria, fungi and other pathogens. The topical application has a composition that comprises, as an active ingredient, at least one species selected from th... | 04/12/2005 |
| 6867229 | Antiparasitic composition for the treatment and protection of pets Composition which is useful in particular for the treatment and protection of domestic animals which are infested with parasites or are likely to be infested with them, these compositions comprising, in the form of a ready-to-use solution: ... | 03/15/2005 |
| 6846837 | Topical administration of basic antifungal compositions to treat fungal infections of the nails Methods and topical pharmaceutical formulations are provided for the treatment of nail fungus (onychomycosis). The invention involves a pharmacologically active antifungal agent, plus a pharmaceutically acceptable base in a formulation having a pH of 7.5 to about 13... | 01/25/2005 |
| 6844364 | Stabilization of retinoid compounds The present invention relates to a method of administering a compound of Formula I: wherein R1 is hydrogen or C1-6-alkyl; R2 is C | 01/18/2005 |
| 6841574 | Topical stabilized prostaglandin E compound dosage forms Compounds of prostaglandin E group (PGE compounds) are stabilized as non-aqueous compositions that include the compound together with a bulking agent that can be a non-aqueous liquid or a solid in a sheet, film or powder form. The composition can optionally include ... | 01/11/2005 |
| 6827942 | Composition and method of use A liquid composition comprising an alcohol or mixture thereof in sufficient quantity to grow hair in an area of canine or feline skin wherein alopecia has occurred. ... | 12/07/2004 |
| 6825234 | Compositions and methods for amelioration of human female sexual dysfunction The invention provides compositions and methods suitable for ameliorating female sexual dysfunction, and in particular, female sexual arousal disorder. In one embodiment, the invention provides a semisolid composition suitable for topical application comprising: an ... | 11/30/2004 |
| 6790867 | Compositions and method for treating infection in cattle and swine Novel formulations combining a non-steroidal anti-inflammatory drug (NSAID) such as flunixin, with a fluorinated chloramphenicol or thiamphenicol derivative antibiotic such as florfenicol are disclosed. Methods for using such formulations in the treatment and preven... | 09/14/2004 |
| 6767533 | Use of a substance binding with the peripheral benzodiazepin receptor for treating skin stress A composition containing a peripheral benzodiazepine receptor ligand for topical use in the treatment of cutaneous stress. ... | 07/27/2004 |
| 6756052 | Device and method for increasing the transdermal permeation of medicaments The invention relates to a device and a method for increasing the transdermal permeation of medications. The invention is characterized in that a constituent which effects a local increase in temperature and/or an increase in blood flow or the skin is administered i... | 06/29/2004 |
| 6737070 | Methods of increasing the efficacy of peroxides This invention relates to methods of increasing the efficacy of peroxides such as benzoyl peroxide in the treatment of skin conditions such as acne. In a preferred embodiment, the invention relates to methods of increasing radicals formed by peroxides on/in the skin... | 05/18/2004 |
| 6737068 | Wipe formulation The present invention relates to a liquid formulation for a feminine wipe. The preferred formulation has an anti-irritant agent, a pH adjuster namely citric acid, and at least one preservative. ... | 05/18/2004 |
| 6733794 | Topical composition for antiseptic and analgesic purposes A composition for topical analgesic and antiseptic use which consists essentially of a approximately equal proportions of alcohol, turpentine, and eucalyptus oil. ... | 05/11/2004 |
| 6730288 | Mousse composition A pharmaceutical aerosol foam composition including an effective amount of a pharmaceutically active ingredient; an occlusive agent; an aqueous solvent; and an organic cosolvent, the pharmaceutically active ingredient being insoluble in both water and the occlusive ... | 05/04/2004 |
| 6719986 | Hyaluronate lyase used for promoting penetration in topical agents The invention relates to an agent for treating skin diseases and/or functional disorders of the skin on the basis of different medicaments and/or auxiliary substances through promotion of penetration from topical formulations into the skin. According to the inventio... | 04/13/2004 |
| 6716441 | Compositions for efficient release of active ingredients The present invention relates to a novel composition for efficiently releasing hydrophilic or water-soluble skin care actives from an oleaginous composition. The substantially oleaginous composition of the present invention comprises: (1) at least one skin care acti... | 04/06/2004 |
