...that after Walter Hunt patented the safety pin in 1849, he sold the rights to it for $400?
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| Number | Title | Issue Date |
| 5112620 | Polyethylene glycol ointment for apthous ulcers A therapeutic ointment having wet adherent properties and particularly well suited for delivery of medicaments to mucosal surfaces includes a base material comprising from about 3 to 15% by weight of a water soluble salt of a copolymer of methyl vinyl eth... | 05/12/1992 |
| 5096891 | Cyclic amp derivative ointments An ointment comprising an adenosine 3',5'-cyclic phosphate derivative as an active ingrediment, an ointment base having water-absorbing and drying properties, a saccharide and/or inorganic high polymer is disclosed. The ointment exhibits improved stabilit... | 03/17/1992 |
| 5093354 | Topical use of 2',4',6'-trimethoxy-4-(1-pyrrolidinyl) butyrophenone A method of treating obstruction dermatoses, ulcus cruris, ulcus cruris venosum and decubital ulcers, is disclosed, which comprises topically treating an affected patient with a therapeutically effective amount of a pharmaceutical composition containing a... | 03/03/1992 |
| 5091422 | Phenethanolamine derivatives Phenethanolamine derivatives are disclosed of formula ##STR1## wherein m is 2 to 8; n is 1 to 7 provided that m+n is 4 to 12; Ar is phenyl or phenyl substituted by one or two halogen atoms, alkyl or alkoxy groups or by an alkylenedioxy group; R1 | 02/25/1992 |
| 5081157 | Compositions and in situ methods for forming films on body tissue A film-forming composition for topical application of medicaments to body tissues. The film-forming composition includes hydroxypropyl cellulose; a non-toxic volatile solvent for said hydroxypropyl cellulose and said reaction product, and an esterificatio... | 01/14/1992 |
| 5081158 | Compositions and in situ methods for forming films on body tissue Medicated protective films are formed in situ on body tissue by applying a composition comprising (a) hydroxypropyl cellulose; (b) an esterification agent which reacts with the hydroxypropyl cellulose to form a reaction product which is soluble in the sol... | 01/14/1992 |
| 5039699 | Anti-peptic ulcer agent An anti-peptic ulcer agent comprising (a) a powdery material which includes tocopheryl retinoate, light silicic anhydride, and an antioxidant; (b) a low substituted hydroxypropylcellulose; and (c) polyvinylpyrrolidone which is orally administrable.... | 08/13/1991 |
| 5037810 | Medical application for heparin and related molecules New uses for heparin, or heparin-like compounds are described that encompass preserving and healing of cells and cell functions arising from transplantations, circumcisions, dermatitides, fissures, fistulas, stimulation of epithelial growth, keloid preven... | 08/06/1991 |
| 5019569 | Reversal of glucocorticoid-induced skin atrophy The present invention is directed to the topical administration of a retinoid-containing pharmaceutical composition for reversing the effects of glucocorticoid-induced skin atrophy.... | 05/28/1991 |
| 5006509 | Use of human growth hormone in treating topical ulcers A new indication for human growth hormone is described. Mixed with an ointment or other based the growth hormone causes an accelerated healing of ulcers. Described is further a method for the treatment of ulcers comprising applying an effective amount of ... | 04/09/1991 |
| 4959357 | Phospholipase A2 inhibitor Potent, specific inhibitors of phospholipase A2 are disclosed which are compounds of the formula: ##STR1## wherein A is R1 CO2 or OH, B is R2 CO2 or OH, D is R3 CO2 or OH an... | 09/25/1990 |
| 4916132 | Use of dihydroergotamine and its salts for the local treatment of trophic disturbances The present invention relates to the use of dihydroergotamine and its salts for the local treatment of trophic disturbances, to drug forms for the local application of dihydroergotamine for the treatment of trophic disturbances and to methods for the prod... | 04/10/1990 |
| 4871752 | Use of aryloxycarboxylic acid derivatives against dermatological diseases The use of aryloxycarboxylic acid derivatives for the production of a medicament against dermatological diseases especially for combatting ulcus cruris, striae distense atrophicae, cellulitis, collagenoses (lupus erythematosus, sclerodermia, dermatomyosit... | 10/03/1989 |
| 4868192 | Pharmaceutical compositions and methods using certain 4H-pyrano (3,2-g) quinoline compounds A pharmaceutical composition comprising, as active ingredient, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dica rbo xylic acid or a pharmaceutically acceptable derivative thereof in admixture with a pharmaceutical acceptable adjuv... | 09/19/1989 |
| 4857328 | Skin therapeutic mixture containing aloe vera extract According to the present invention, a skin therapeutic mixture is useful for the alleviation of certain skin disorders such as acne, psoriasis, burns, pimples, blackheads, and open sores, and such mixture comprises: the therapeutic agent being the extract... | 08/15/1989 |
| 4855138 | Skin therapeutic mixture containing Matico extract According to the present invention, a skin therapeutic mixture is useful for the alleviation of certain skin disorders such as acne, psoriasis, burns, pimples, blackheads, and open sores, and such mixture comprises: the therapeutic agent being the extract... | 08/08/1989 |
| 4847084 | Ointment for the treatment of decubiti ulcers These 2 formulae provide a new and unique method of healing decubiti ulcers. Formula #1 contains Fibrinolysin and Desoxyribonuclease, Combined-Bovine-with Chloramphenicol Ointment, Chlorophyll Ointment 0.5%, and Povidone-Iodine Ointment 10% in equal parts... | 07/11/1989 |
| 4829082 | Pharmaceutical compositions for the treatment of skin diseases This invention relates to pharmaceutical compositions for the treatment of skin diseases which comprises as an active ingredient vitamin A esters of -tocopherol.... | 05/09/1989 |
| 4749572 | Pharmaceutical preparations A pharmaceutical preparation for the treatment of, e.g. ulcers, burns and skin diseases contains, as essential ingredients, from 5 to 25% by weight of Peru Balsam and from 0.01 to 0.20% by weight of silver nitrate. The preparation may be administered ente... | 06/07/1988 |
| 4684632 | Formulation with special 1,2-diacylglycero-3-phosphocholines for the treatment of gastrointestinal disorders Pharmaceutical formulations for the treatment of gastrointestinal disorders, which contain as the active component an effective gastrointestinal disorder alleviating amount of a 1,2-diacylglycero-3-phosphocholine in which 75-86% by weight of the acyl ... | 08/04/1987 |
| 4581226 | Method of treating sensitive animal tissue with a specially processed seawater solution A method of treating various sensitive animal body tissues comprising applying to the tissue a solution prepared from specially processed seawater. The solution is prepared by filtering off-shore seawater to remove debris in small organisms, sterilizing t... | 04/08/1986 |
| 4577022 | Silyl compounds The invention provides new silyl derivatives of 5,6,7,8-tetrahydroquinolines and related compounds. The tetrahydroquinolines are substiuted at the 8-position by the group SiR3 where R may be one of various hydrocarbon groups or an electron ... | 03/18/1986 |
| 4557754 | Bis-(N,N-dimethyl-N-carbodecyloxymethyl-N-ethylene-ammonium)-sulphide dichloride and use thereof A novel compound bis-(N,N-dimethyl-N-carbodecyloxymethyl-N-ethyleneammonium)-sulphide dichloride of the formula ##STR1## A method for preparing said novel compound comprising quaternization of bis-(ଲ-dimethylaminoethyl)-sulphide with monoc... | 12/10/1985 |
| 4557935 | Germicidal composition A germicidal composition consists of an aqueous suspension of hydrophilic lipid crystals of 1-monolaurin, and preferably also 1-monomyristin, in a quantity of 20-30 percent by weight, and hydrogen peroxide in a quantity of 0.2-5 percent by weight. The hyd... | 12/10/1985 |
| 4434179 | Wound-healing promoters Compounds of formula (I): ##STR1## (wherein: R1 represents a hydroxy group, a C1 -C8 alkoxy group, an aliphatic acyloxy group, a benzoyloxy group or a cinnamoyloxy group; p1 R2 represents a hydrogen atom, a... | 02/28/1984 |
| 4427685 | Cycloalkylamino derivatives and their use in the treatment of peptic ulcers and the like Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein: a is 1 to 3; b is 0 to 2; c is 2 to 4; d is 1 to 5; X is sulphur, oxygen or --CH2 --; Y is oxygen, sulphur, NR4 or CHR5 wherein R4 | 01/24/1984 |
| 4424232 | Treatment of herpes simplex Herpes simplex, cold sores, lesions, warts, blisters, burns, ulcers, and other painful skin conditions are treated by topical application of a composition comprising L-lysine, gibberellic acid, and urea in an inert carrier comprising water. The compositio... | 01/03/1984 |
| 4414202 | Composition for treatment of wounds Treatment of skin wounds with starch hydrolysate composition can be improved by irrigating the wound with a buffered salt solution having a pH in the range of approximately 6-7.8 prior to application of the starch hydrolysate composition. Additionally, th... | 11/08/1983 |
| 4405610 | Drug for curing inflammatory and/or degenerative and/or atrophic mucous-membrane diseases The invention relates to a pharmacuetical agent for curing inflammatory and/or degenerative and/or atrophic mucous-membrane diseases, more particularly for local application, which are characterized by the proportion of the nucleoside inoside (=hypoxanthi... | 09/20/1983 |
| 4402975 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical uses thereof A compound represented by the following formula ##STR1## wherein R1 represents a hydrogen atom, an acyl group or an alkoxycarbonyl group; X1 represents an alkylene group having 3 to 6 carbon atoms, a 1,4-cyclohexylene group, or ... | 09/06/1983 |
| 4385057 | Diphenylbutyl-piperazinecarboxamides in pharmaceutical compositions and methods Compounds having the general formula ##STR1## as herein defined and pharmaceutically acceptable acid addition salts thereof. Pharmaceutical compositions containing said compounds. Methods of treatment of humans and animals by such compounds and compo... | 05/24/1983 |
| 4366169 | Use of perfluorocarbons as wound treatment Victims suffering certain types of wounds are treated by contacting the wound with a substantially fluorinated carbon material or a mono- or di-brominated derivative thereof containing molecular oxygen.... | 12/28/1982 |
| 4259244 | Certain 13,14-didehydro-PGI1 compounds Bicyclic prostaglandins having numerous pharmaceutical and veterinary utilities including, for example, use as hypotensive, vasodilatory, anti-aggregating, cytoprotective, and bronchodilatory agents. Pharmaceutical and veterinary compositions comprising t... | 03/31/1981 |