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| Number | Title | Issue Date |
| 4500540 | Thromboxane synthase inhibitors as insulin lowering agents and antionbesity agents The present disclosure relates to the use of thromboxane synthase inhibitors as antiobesity agents and insulin lowering agents. Such compounds fall into a variety of classes among which are 1-substituted imidazoles, 4-substituted imidazoles, 3-substituted... | 02/19/1985 |
| 4439435 | Isoureas and isothioureas The compounds are isoureas and isothioureas which have an O- or S- alkylpyrimidone substituent and which are histamine H2 -antagonists and antiinflammatory agents. A specific compound of this invention is 2-[5-(O-isoureido)pentylamino]-5-(6-met... | 03/27/1984 |
| 4407824 | Pharmaceutical preparations for topical application which contain salts of alkanecarboxylic acids, novel carboxylic acid salts and the production thereof The invention relates to pharmaceutical preparations for topical application which contain salts of alkanecarboxylic acids, in particular compounds of the formula ##STR1## wherein R1 is a group of the formula ##STR2## wherein X | 10/04/1983 |
| 4407823 | Novel phenylacetic acid derivatives Phenylacetic acid derivatives of the formula ##STR1## wherein n is an integer of 2 to 5; ##STR2## R1 is hydrogen, halogen, trifluoromethyl, nitro or amino; R2 and R3 each independently is hydrogen or lower alkyl;... | 10/04/1983 |
| 4366164 | Amine derivatives The invention provides compounds of general formula ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof, in which Y and Z, which may be the same or different, each represent oxygen, sulphur, .dbd.CHNO2 or .dbd... | 12/28/1982 |
| 4361571 | 3-Carbamoyl-6-aminopyridinium and analogues, and their use in treating skin disorders Systemic as well as topical treatment to alleviate the symptoms of skin disorders characterized by inflammation or disturbed keratinization comprising as the principal active ingredient, one or more 3-carbamoyl-6-aminopyridinium compounds, is disclosed. I... | 11/30/1982 |
| 4361572 | Tetrahydronicotinamide derivative, pharmaceutical compositions and use 1,4,5,6-Tetrahydronicotinamide derivative represented by the formula: ##STR1## (wherein R is defined in the specification), a process of preparing the same and pharmaceutical composition containing the same are disclosed. The compound has action for suppr... | 11/30/1982 |
| 4356185 | Thiazoles The invention concerns compounds of formula ##STR1## or salts thereof, wherein R represents an acyl group which possess anti-inflammatory activity and have low toxicity. Methods for preparing the compounds and pharmaceutical compositions are also dis... | 10/26/1982 |
| 4346109 | Method of treating keratotic skin disease A compound, 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid, and a salt thereof are disclosed as a therapeutic agent for treatment of skin diseases with keratinization.... | 08/24/1982 |
| 4284785 | Substituted phenyl esters of isoxazolecarboxylic acids Isoxazolecarboxylic acid phenyl esters which are intermediates for the preparation of anti-inflammatory agents.... | 08/18/1981 |
| 4208406 | Composition for the treatment and prevention of skin, eye and mucosal inflammation Composition for treatment or prevention of skin, eye or mucosal inflammation in human and animals, especially but not exclusively by external topical application comprising an effective amount of a cyclic nucleotide derivative having the following structu... | 06/17/1980 |
| 4207315 | Process for treating proliferative skin diseases using certain diamino compounds A process and pharmaceutical compositions for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans or domesticated animals, topically and/or parenterally, and/or systemically a composition ... | 06/10/1980 |
| 4200648 | Method of treatment This invention describes a method of treating inflammation in warm-blooded animals by topically administering an effective amount of a benzylideneaniline derivative, and the compositions therefore.... | 04/29/1980 |
| 4192890 | Novel benzoylphenylacetic acid esters Racemates [and optically active isomers of benzoylphenylacetic acid esters of the formula ##STR1## wherein R is selected from the group consisting of hydrogen and alkyl of 1 to 7 carbon atoms, and the two benzene rings may be optionally substituted ... | 03/11/1980 |
| 4147777 | Sericosides and method of use Pharmaceutically active compounds of the formula ##STR1## wherein R1, R2, R3 and R4, which may be the same or different, each represents a hydrogen atom or a substituted or unsubstituted aliphatic or aromat... | 04/03/1979 |
| 4145348 | 2-[[5-(4-Chlorophenyl)furfurylamino]methyl]pyridine dihydrochloride 2-[[5-(4-Chlorophenyl)furfurylamino]methyl]pyridine dihydrochloride is useful as an anti-inflammatory agent.... | 03/20/1979 |
| 4112075 | Furanose-O-pyridylcarboxylic acid esters The invention relates to furanose-O-pyridylcarboxylic acid esters, such as the ethyl-2-O-methyl-3,5,6-tri-O-nicotinoyl-D-glucofuranoside, which have anti-inflammatory activity and are fibrinolysis activators. They can be used for the treatment of rheumati... | 09/05/1978 |
| 4053600 | Tricyclic 1,2,4-triazolo-quinazolines The invention discloses 5-substituted-1,2,4-triazolo[4,3-c]quinazolines and 1,2,4-triazolo[1,5-c]quinazolines having pharmacological activity in animals and useful, for example, as hypotensive and anti-inflammatory agents. The compounds may be prepared, f... | 10/11/1977 |
| 4001245 | 2-[2-(Pipe ridino)ethyl]-10,10a-dihydro-1H,5H-imidazo[1,5-b]isoquinolin-1,3(2H)-dion e The title compound possesses pharmacological activity as an anti-inflammatory agent.... | 01/04/1977 |
| 3998966 | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof 2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the -position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the nap... | 12/21/1976 |
| 3993657 | [5-(4-Nitrophenyl)-2-furoylmethyl]pyridinium bromide [5-(4-nitrophenyl)-2-furoylmethyl]pyridinium bromide is useful as an anti-inflammatory agent.... | 11/23/1976 |
| 3968142 | Hydronaphthalene carboxylic acids and derivatives Compounds of the formula ##EQU1## in which Ph represents an ortho-phenylene radical which contains in position 4 or 5 an unsubstituted or substituted hydrocarbon radical of aliphatic character, R represents a lower alkyl radical or especially a ... | 07/06/1976 |
| 3965102 | 1,2,3,4,6,7,8,8A-Octahydro-6-aryl-isoquinolines and derivatives thereof 1,2,3,4,6,7,8,8a-Octahydro-6-phenyl or substituted phenyl-isoquinolines and derivatives thereof and their methods of preparation are disclosed. These compounds are useful as anti-inflammatory agents.... | 06/22/1976 |
| 3963724 | Intermediates useful in the preparation of aryldecahydropyrrolo[3,4-f]quinolines Various intermediates useful in the preparation of 4-aryl-2,3,3a,4,5,6,7,8,9,9b-decahydro-1H-pyrrolo[3,4-f]quinolines are disclosed.... | 06/15/1976 |
| 3962434 | 3-Aryl-triazene-1-oxides for treating inflammatory diseases 3-Aryl-triazene-1-oxides are useful for treating inflammatory diseases.... | 06/08/1976 |
| 3957795 | Novel cyclopentene and cyclopentane derivatives The present invention is concerned with novel cyclopentene and cyclopentane derivatives which have pharmacological, particularly analgesic and antiinflammatory activity, and are also useful intermediates in the preparation of other pharmacologically activ... | 05/18/1976 |
| 3957994 | Topical anti-inflammatory composition and method of use There is disclosed a novel topical anti-inflammatory composition comprising theophylline and 2-pyrrolidone or an N-lower alkyl-2-pyrrolidone.... | 05/18/1976 |
| 3933833 | Phenyl -thiourea, -carbothioamide and -carbonothioamide derivatives Disclosed are various phenyl -thiourea, -carbothioamide and -carbonothioamide derivatives which are useful in alleviating symptoms and conditions of inflammation.... | 01/20/1976 |
