Quotables
"The production of too many useful things results in too many useless people."
Karl Marx
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7378111 | Regulation of GSK-3α activity for the treatment or prevention of Alzheimer's disease Provided is a novel use of therapeutic concentrations of an inhibitor of glycogen synthase kinase-3 (GSK-3), including lithium or any other GSK-3 inhibitor, to block, reduce or inhibit processing of amyloid precursor proteins to beta-amyloid (Aβ) peptides, which ar... | 05/27/2008 |
| 7365049 | Afamin-containing compositions and methods of use The use of Afamin, in particular in combination with vitamin E is described for producing a preparation for the treatment of oxidative stress. ... | 04/29/2008 |
| 7256184 | Treatment of aging disorders in humans A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of one or more cell-specific carbonic anhydrase enzymes. Such conditions include chronic neurodegenerative conditions including... | 08/14/2007 |
| 7244708 | Inhibitors of memapsin 2 and use thereof Methods for the production of purified, catalytically active, recombinant memapsin 2 have been developed. The substrate and subsite specificity of the catalytically active enzyme have been determined and were used to design substrate analogs of the natural -2 substr... | 07/17/2007 |
| 7011854 | Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g., rheumatoid arthritis, and of diseases with a strong inflammatory component, such as atherosclerosis, stroke... | 03/14/2006 |
| 6821997 | Therapeutic and prophylactic treatment of aging and disorders of aging in humans A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of cell-specific carbonic anhydrase enzymes in the brain, such as conditions associated with chronic neurodegenerative conditio... | 11/23/2004 |
| 6759049 | Pharmaceutical or dietetic mushroom-based compositions The invention concerns the field of pharmaceutics and dietetics. More particularly, the invention concerns pharmaceutical and/or dietetic mushroom-based compositions, characterised in that they contain one or several edible mushrooms with therapeutic properties and ... | 07/06/2004 |
| 6660757 | Use of riluzole in the treating acoustic traumas The invention concerns the use of riluzole or one of its pharmaceutically acceptable salts for preventing and/or treating acoustic traumas and, in particular, different types of deafness and tinnitus.... | 12/09/2003 |
| 6608064 | Pharmaceutical agents for the treatment of Parkinson's disease, ADHD and microadenomas The present invention is directed to the use of certain pyrido[1,2-a]-pyrazine derivatives, also described as bis-azabicyclic compounds and defined by the formula (I) herein, in the treatment of Parkinson's disease, attention deficit hyperactivity disorde... | 08/19/2003 |
| 6599935 | Felbamate derived compounds The present invention relates to novel felbamate derivatives and their use to treat neurological diseases such as epilepsy and to treat tissue damage resulting form ischemic events. The felbamate derivatives are modified to prevent the formation of metabo... | 07/29/2003 |
| 6596709 | 6-sulphanoyl-3-quinolylphosphonic acid compounds The invention relates to a compound of formula (I): ##STR1## wherein: X represents chlorine or fluorine or CF3, R represents hydrogen or a group ##STR2## and methods for using the same.... | 07/22/2003 |
| 6552087 | Therapeutic agent comprising (+)-sibutramine The use of (+)-sibutramine in the treatment of depression, obesity, Parkinson's disease, cerebral function disorders and diabetes is described.... | 04/22/2003 |
| 6509381 | Method of preparing and using compositions extracted from vegetable matter for the treatment of neurological conditions A composition is prepared by extracting and isolating phytochemical fractions from plant matter for treatment for neurological conditions and especially for migraine headaches, inflammations, dementia, and Alzheimer's Disease. The composition is enriched,... | 01/21/2003 |
| 6506746 | Method for treating cognitive dysfunction The invention provides a method of treating a cognitive dysfunction comprising administering an effective amount of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b][1,5]benzodiazepine.... | 01/14/2003 |
| 6458820 | Method for preventing or the progression of neuronal damage with pramipexole as a neuroprotective agent The present invention provides the use of pramipexole as a neuroprotective agent.... | 10/01/2002 |
| 6391310 | Method of preparing and using isoflavones for the treatment of neurological symptoms A composition is prepared by extracting phytochemicals from plant matter and is administered to provide treatment for mental conditions and nerve problems, especially neurological symptoms, immunological symptoms, migraine headaches, inflammations and dem... | 05/21/2002 |
| 6380267 | Composition and method for decreasing neurologic symptomatology A method of decreasing the signs or symptomatology in a patient with a neurologic condition or disease, or in a patient due to effects of exposure to an exogenous substance, such as a pharmaceutical agent, comprising selecting a patient having at least on... | 04/30/2002 |
| 6358527 | Fast-dissolving galanthamine hydrobromide tablet The present invention is concerned with a fast-dissolving tablet for oral administration comprising as an active ingredient a therapeutically effective amount of galanthamine hydrobromide (1:1) and a pharmaceutically acceptable carrier, characterized in t... | 03/19/2002 |
| 6350467 | Pharmaceutical preparations of glutathione and methods of administration thereof A method of increasing glutathione levels in mammalian cells comprising administering an oral bolus of encapsulated pharmaceutically stabilized glutathione in a rapidly dissolving formulation to a mammal on an empty stomach. Pharmaceutical formulations in... | 02/26/2002 |
| 6348213 | Method for reversing age-related changes in heart muscle cells A method of-treating a relatively aged animal to reverse age-related changes in the lipid composition of organ and tissue cells, such as heart muscle cells, and the ability of the animal to withstand respiratory stress. A suspension of small unilamellar v... | 02/19/2002 |
| 6342515 | Remedy for neurodegenerative diseases The present invention provides a medicament for neurodegenerative diseases comprising zonisamide or an alkali metal salt thereof as an active ingredient. The present medicament can be used in the prevention and treatment of neurodegenerative diseases such... | 01/29/2002 |
| 6300329 | Pharmaceutical agents for the treatment of Parkinson's disease, ADHD and microadenomas The present invention is directed to the use of certain pyrido[1,2-a]-pyrazine derivatives, also described as bis-azabicyclic compounds and defined by the formula (I) herein, in the treatment of Parkinson's disease, attention deficit hyperactivity disorde... | 10/09/2001 |
| 6277886 | Pharmaceutical compositions comprising S-(-)-N-propargyl-1-aminoindan Pharmaceutical compositions for the treatment of a neurological disorder of neurotrauma or for improving memory in a patient comprising a therapeutically effective amount of S-(-)-N-proparygl-1-aminoindan or a pharmaceutically acceptable salt thereof as a... | 08/21/2001 |
| 6254853 | Water soluble pro-drugs of propofol This invention provides esters of propofol (2,6,-diisoprophenol). The propofol esters are soluble in water and metabolize rapidly to propofol in the body. The propofol esters are useful as pro-drugs for the same indications as propofol. This invention als... | 07/03/2001 |
| 6238689 | Intestinal absorption of nicotine to treat nicotine responsive conditions A delayed and sustained release composition of an additive and/or toxic agent such as nicotine is delivered systemically in therapeutic amounts while avoiding the peak plasma levels which gives rise to addiction and/or toxic side effects. The composition ... | 05/29/2001 |
| 6187756 | Composition and methods for treatment of neurological disorders and neurodegenerative diseases It has been discovered that the stimulation of ଲ-adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo exposure of neuronal cells to certain compositions comp... | 02/13/2001 |
| 6184255 | Pharmaceutical composition comprising coenzyme Q10 The present invention has for its object to provide a medicinal composition comprising coenzyme Q10 as an active ingredient, which composition features an enhanced absorption after oral administration. The present invention is directed to a med... | 02/06/2001 |
| 6180678 | Use of adrafinil to treat behavioral problems in aged canines A method of treating age related behavorial problems in dogs is disclosed. The method involves administering adrafinil or a metabolite thereof to an animal in need of such treatment.... | 01/30/2001 |
| 6159500 | Pharmaceutical preparations of glutathione and methods of administration thereof A method for the administration of glutathione orally comprising the administration of a bolus of glutathione which is pharmaceutically stabilized and encapsulated. The glutathione is administered on an empty stomach. The preferred stabilizer is ascorbic ... | 12/12/2000 |
| 6156777 | Use of pramipexole as a neuroprotective agent The present invention provides the use of pramipexole as a neuroprotective agent.... | 12/05/2000 |
| 6087372 | Method of enhancing cognition with 2-(4-methoxyphenyl)-pyrazolo[4,3-c]quinolin-3-one The present invention provides the use of 2-(4-methoxyphenyl)-pyrazolo[4,3-c]quiniolin-3-one or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for enhancing cognition, particularly in Alzheimer's Disease, a method of enhanc... | 07/11/2000 |
| 6077852 | Treatment of central nervous system disorders with selective estrogen receptor modulators The present invention provides a method of treating depression, mood swings, or Alzheimer's disease in a patient in need of such treatment by administering a selective estrogen receptor modulating compound of the formula ##STR1## in which R... | 06/20/2000 |
| 5866160 | Composition of soft-shelled turtle and tortoise The present invention relates to a composition of soft-shelled turtles and tortoises (TT composition) and a method for the preparation of the same. It also relates to the extensive use which is beneficial to human being.... | 02/02/1999 |
| 5843892 | Stimulation of nerve growth and/or vitality The protein, cholinergic neuronal differentiation factor (CDF), also known as leukemia inhibitory factor (LIF), is described, together with the use of the polypeptide to stimulate neuron growth and survival in animals either by direct administration or by... | 12/01/1998 |
| 5795880 | Method and composition for treating obesity and related disorders in animals comprising dehydroepiandrosterone (DHEA), or a derivative thereof, and an anorectic agent The invention describes a method and composition for treating obesity or related disorders in animals using an anorectic agent and dehydroepiandrosterone (DHEA). The composition effectively diminishes caloric intake, may alter metabolism, weight gain, or ... | 08/18/1998 |
| 5716632 | Compositions and methods for reparation and prevention of fibrotic lesions In a preferred embodiment, drugs having pharmacological properties which are useful in the medicinal therapy of fibrotic disease for the reparation and prevention of fibrotic lesional tissues, such drugs including as active ingredient(s) one or more N-sub... | 02/10/1998 |
| 5668117 | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments Therapeutic compositions comprising an effective amount of at least one carbonyl trapping agent alone or in combination with a therapeutically effective of a co-agent or medicament are disclosed. The compositions are used to treat a mammal suffering from ... | 09/16/1997 |
| 5650420 | Pramipexole as a neuroprotective agent The present invention provides the use of pramipexole as a neuroprotective agent.... | 07/22/1997 |
| 5589182 | Compositions and method of treating cardio-, cerebro-vascular and alzheimer's diseases and depression A pharmaceutical composition suitable for the treatment of a condition selected from the group consisting of cardiovascular disease, cerebrovascular disease, Alzheimer's disease, depression or combinations thereof comprising various mixtures of the aqueou... | 12/31/1996 |
| 5527788 | Method and composition for treating obesity comprising dehydroepiandrosterone (DHEA), or a derivative thereof, and an anorectic agent The invention describes a method and composition for treating obesity or related disorders in animals using an anorectic agent and dehydroepiandrosterone (DHEA). The composition effectively diminishes caloric intake, may alter metabolism, weight gain, or ... | 06/18/1996 |
