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| Number | Title | Issue Date |
| 7344740 | Methods and apparatus to prevent, treat, and cure the symptoms of nausea caused by chemotherapy treatments of human cancers Methods and apparatus are provided to prevent, treat, and cure chemotherapy induced nausea in human beings. The inhalation of an effective amount of vaporized essential oil from Mentha piperita (peppermint oil) has been shown in practice to prevent, treat, an... | 03/18/2008 |
| 7335664 | Colon cleansing composition and method A composition and method for cleansing a colon prior to endoscopic procedure. More particularly, a combination of bisacodyl, metoclopramide, sodium, and/or a phosphorus containing composition administered in sequential doses for preparing a colon prior to colonoscop... | 02/26/2008 |
| 7214692 | Medical use for tachykinin antagonists The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their preparation, pharm... | 05/08/2007 |
| 7049319 | Colon cleansing composition and method A composition and method for cleansing a colon prior to endoscopic procedure. More particularly, a combination of bisacodyl, metoclopramide, sodium, and/or a phosphorus containing composition administered in sequential doses for preparing a colon prior to colonoscop... | 05/23/2006 |
| 6645532 | Compositions and method for relieving discomfort in the ears Generally, the method for preventing or relieving discomfort in the ears arising from congestion and/or obstruction of in the eustachian tubes comprising or changes in middle ear pressure relative to atmospheric pressure arising from environmental conditi... | 11/11/2003 |
| 6436961 | Pharmaceutical agents for the treatment of emesis The present invention relates to a novel process for preparing and resolving 3-amino-2-phenylpiperidine and for synthesizing from the enantiomers of such compound certain pharmaceutically active substituted 2-phenyl-3-benzylaminopiperidines. The substitut... | 08/20/2002 |
| 6329394 | Medical use for tachykinin antagonists The present invention relates to the use of certain tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis.... | 12/11/2001 |
| 6326383 | Medical use for tachykinin antagonists The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their prepara... | 12/04/2001 |
| 6306425 | Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol An injectable slow-release naltrexone formulation is provided comprising naltrexone in a poly(D,L-lactide) matrix with a small amount of residual ethyl acetate. Upon intramuscular injection of the composition, naltrexone is released in a controlled manner... | 10/23/2001 |
| 6294548 | Multidose vial formulations for administering endo-N-(9-methyl-9-azabicyclo[3.3. 1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride Invented are improved multidose aqueous formulations of endo-N-(9-methyl-9-azabicyclo[3.3.1. ]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride.... | 09/25/2001 |
| 6235735 | Morpholine and thiomorpholine tachykinin receptor antagonists Substituted heterocycles of the general structural formula: ##STR1## are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis, and calcium channel blockers useful in the treatment of cardiov... | 05/22/2001 |
| 6197329 | Anti-nausea compositions and methods The present disclosure is directed to novel nutritional anti-nausea compositions, anti-emetic compositions, and methods of using same. The compositions provide improved relief from nausea and/or vomiting. The compositions are particularly useful for pregn... | 03/06/2001 |
| 6159965 | Anti-emetic pharmaceutical compositions containing methotrimeprazine A non-sedating anti-emetic composition in oral unit dosage form comprising from 1 to 5 mg of methotrimeprazine per unit dosage, or in unit dosage form for parenteral administration comprising from 1 to 5 mg of methotrimeprazine in each unit dosage.... | 12/12/2000 |
| 6048859 | Morpholine and thiomorpholine tachykinin receptor antagonists Substituted heterocycles of the general structural formula: ##STR1## are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis, and calcium channel blockers useful in the treatment of ca... | 04/11/2000 |
| 6001807 | Use of CRF-antagonists for treating emesis CRF-antagonists are useful in the treatment of emesis.... | 12/14/1999 |
| 5798363 | Use for tachykinin antagonists to treat emesis The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their prepara... | 08/25/1998 |
| 5661142 | Anti-emetic composition The invention relates to an anti-emetic composition that comprises dexamethasone (DEX), metoclopramide (MTC) and an antihistamine or an anticholinergic agent. In a particular embodiment, a composition containing DEX:MTC:diphenhydramine in a relative weigh... | 08/26/1997 |
| 5621004 | Method for treating emesis A method of treating emesis in a warm blooded animal by administering an anti-emesis effective amount of a nitric oxide synthase inhibitor and compositions containing the same.... | 04/15/1997 |
| 5618834 | Indole derivatives in the treatment of emesis Compounds of formula I, ##STR1## wherein R1 represents hydrogen; R2 represents hydrogen, halogen, cyano, OR4, --(CH2)m CONR5 R6, --(CH2)m SO2 | 04/08/1997 |
| 5576317 | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis The present invention relates to a method of treating or preventing emesis in a mammal, including a human, by administering to the mammal a 5HT3 receptor antagonist and an NK-1 receptor antagonist (e.g., a substance P receptor antagonist). It a... | 11/19/1996 |
| 5538982 | Medical use for tachykinin antagonists The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their prepara... | 07/23/1996 |
| 5470868 | Methods for treating emesis and nausea using optically pure R(+) ondansetron Methods are disclosed utilizing the optically pure R(+) isomer of ondansetron. This compound is a potent drug for the treatment of nausea and vomiting associated with chemotherapy and radiation therapy, while avoiding the concomitant liability of adverse ... | 11/28/1995 |
| 5393762 | Pharmaceutical agents for treatment of emesis The present invention relates to a method of treating or preventing emesis in mammals, including humans, using certain quinuclidine derivatives, piperidine derivatives, azanorbornane derivatives and related compounds.... | 02/28/1995 |
| 5364854 | Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation Derivatives of 2,3,3a,4-tetrahydro-2-azabicyclo alkyl-1H-imidazo[5,1,-c][1,4]benzoxazin-1-one are provided of general formula (I) ##STR1## in which inter alia R3 represents ##STR2## wherein n is an integer of 1 or 2 and R8 | 11/15/1994 |
| 5360820 | Medical use for tachykinin antagonists The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their prepara... | 11/01/1994 |
| 5273759 | Method and composition for treating the migraine complex An oral composition comprising in combination acetaminophen, dimenhydrinate and one or more antacid ingredients has been shown to be effective in the treatment of acute migraine attacks.... | 12/28/1993 |
| 5242929 | Derivatives of substituted imidazol-2-one and process for their preparation Derivatives of 1-phenyl-3-azabicycloalkylimidazolidin-2-ones are provided of general formula (1) ##STR1## in which inter alia R represents a group ##STR2## wherein n is an integer of 1 or 2 and R8 is hydrogen, C1 -C | 09/07/1993 |
| 5236931 | 2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol This invention provides novel 3-quinuclidinyl benzamides and benzoates which have utility as therapeutical agents which exhibit anxiolytic, antipsychotic, cognition improvement, antiemetic and gastric prokinetic effects in warm blooded animals. The compou... | 08/17/1993 |
| 5202318 | Tricyclic compounds acting at serotonin receptor subtypes Compounds of Formula I: ##STR1## in which Z is CH2 or C.dbd.O; X and Y are independently selected from hydrogen, halogen, hydroxy, lower alkoxy, lower alkyl, nitro, amino, aminocarbonyl, (lower alkyl)amino, di(lower alkyl)amino and (lower ... | 04/13/1993 |
| 5202333 | Tricyclic 5-HT3 receptor antagonists The present invention is directed to 5-HT3 receptor antagonist compounds of formula I: ##STR1## in which the dashed line denotes an optional double bond; n is 1, 2 or 3; p is 0, 1, 2 or 3; q is 0, 1 or 2; each R1 is independently sel... | 04/13/1993 |
| 5202325 | Use of ergoline derivatives in treating emesis Compounds of the formula I ##STR1## wherein n is 1 or 2, R1 represents a hydrogen atom or a C1 -C4 alkyl group, R2 represents a hydrogen atom and R3 represents a hydrogen atom or a hydroxy group ... | 04/13/1993 |
| 5166145 | Antiemetic therapy A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.... | 11/24/1992 |
| 5102872 | Controlled-release formulations of interleukin-2 Shipping fever, and other stress-related diseases in livestock, are treated by administration of a microencapsulated composition comprising IL-2 conjugated with a polyoxyethylene polymer, and mixed with a release-modulating amount of humen serum albumin. ... | 04/07/1992 |
| 5081153 | Sterile parenteral composition A parenteral pharmaceutical composition comprising metoclopramide or a pharmaceutically acceptable salt thereof, and from 0 to 0.06% by weight, preferably from 0 to 0.006% by weight, of the composition of sodium metabisulphite, in combination with a pharm... | 01/14/1992 |
| 5051400 | Method of treating nausea and emesis related to motion sickness with vasopressin antagonists Vasopressin derivatives having V1 antagonist activity which alleviate the symptoms of motion sickness. More specifically, the vasopressin V1 antagonists of this invention are employed to prevent nausea and emesis associated with moti... | 09/24/1991 |
| 5039528 | EAA antagonists as anti-emetic drugs This invention relates to a method and a class of pharmaceutical agents for suppressing vomiting, nausea, and other emetic symptoms. The method involves administering to a susceptible mammal a glutamate (EAA) receptor antagonist at an anti-emetically effe... | 08/13/1991 |
| 5013560 | Microbially-stable bismuth-containing liquid pharmaceutical suspensions Microbially-stable liquid pharmaceutical suspensions for oral administration comprising a bismuth-containing pharmaceutical agent, benzoic acid, sorbic acid, a suspension system and water, and wherein said compositions have a pH within the range of from a... | 05/07/1991 |
| 5011688 | Liquid composition for the relief of premenstrual and menstrual discomforts A liquid composition for the relief of premenstrual and menstrual discomfort comprising, as active pharmaceutical agents, an effective amount of an analgesic, an antihistamine, and a diuretic, said active agents being dissolved in a liquid vehicle, said c... | 04/30/1991 |
| 5010108 | N-cycloalkylaminoethylbenzamide derivatives, their synthesis and pharmaceutical preparations New N-(2-cycloalkylamino)ethyl-substituted benzamides having a powerful stimulating activity on gastric motility and with a low central anti-dopaminergic activity are described. The synthesis and the pharmaceutical preparation for therapeutical use are al... | 04/23/1991 |
| 4983621 | Medicaments The invention relates to the co-administration in human or veterinary medicine of 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carba zol-4-one or a physiologically acceptable salt or solvate thereof and a cyclo-oxygenase inhibi... | 01/08/1991 |
