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| Number | Title | Issue Date |
| 7205127 | Methods of treating insulin resistance with an inhibitor of an NAD(P)H oxidase The present invention relates to the use of NAD(P)H oxidase inhibitors to increase cellular uptake of glucose and in the treatment and/or prevention of diseases caused by insulin resistance or diseases related thereto, such as type II diabetes. Specifically, the inv... | 04/17/2007 |
| 7186686 | Formulated composition A composition is disclosed that comprises a mixture of polypeptides of opposite charge and an excipient selected from the group consisting of arginine, lysine, glutamic acid, sodium dodecyl sulfate, beta-hydroxy cyclodextrin, and beta-cyclodextrin sulfobutyl ether. | 03/06/2007 |
| 7183266 | Dual induced viscosity fiber system and uses thereof The present invention relates generally to a method of blunting the postprandial glycemic response to a meal by feeding a dual induced viscosity fiber system. The first component of the induced viscosity fiber system is soluble fiber. The second component of the ind... | 02/27/2007 |
| 7179842 | Method of treating non-insulin dependent diabetes mellitus with phytanic acid derivatives The present invention is a method for the treatment or prevention of preferably non-insulin dependent (NIDDM or so-called Type II) diabetes mellitus, or other conditions associated with impaired glucose tolerance such as obesity, and in particular to the use of phyt... | 02/20/2007 |
| 7166579 | Prodrugs of DP IV-inhibitors Prodrug compounds of unstable inhibitors of the serine peptidase dipeptidyl peptidase IV, are used in the treatment of various disorders, especially of metabolic disorders. The Prodrug compounds can be used in the treatment of impaired glucose tolerance, glucosuria,... | 01/23/2007 |
| 7153877 | Method and composition for preventing or reducing the symptoms of insulin resistance syndrome A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bo... | 12/26/2006 |
| 7144856 | Inhibitors of dipeptidyl peptidase I The present invention relates to specific inhibitors of the cysteine protease dipeptidyl peptidase I (DP I)which can be used in the treatment of malignant cell degeneration, immune diseases impaired wound healing and metabolic diseases of humans and are represented ... | 12/05/2006 |
| 7141254 | Synergistic composition for the treatment of diabetes mellitus The present invention relates to a synergistic composition for the treatment of diabetes in a subject in need thereof, said composition-comprising Trigonelline of concentration ranging between 20 to 30%, amino acids of concentration ranging between 20 to 60%, and so... | 11/28/2006 |
| 7141558 | 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds Biologically active 19-nor vitamin D analogs substituted at C-2 in the A-ring with an ethylidene or an ethyl group. These compounds have preferential activity on mobilizing calcium from bone and either high or normal intestinal calcium transport activity which allow... | 11/28/2006 |
| 7138107 | Inhibition of olfactory neurosensory function to treat eating disorders and obesity The use of calcium channel blockers administered intra-nasally to inhibit olfactory sensory perception to treat eating disorders, including obesity, is described. Also described is a method of reducing food intake in a subject by administering a pharmaceutical compo... | 11/21/2006 |
| 7138115 | Use of IL-12 and IL-12 antagonists in the treatment of autoimmune diseases Method of treating autoimmune conditions are disclosed comprising administering to a mammalian subject IL-12 or an IL-12 antagonist. In certain preferred embodiments the autoimmune condition is one which is promoted by an increase in levels of IFN-γ or TNF-α. Suit... | 11/21/2006 |
| 7138486 | Insulinotropic hormone derivatives and uses thereof Derivatives of glucagon-like peptide I (GLP-1) and especially GLP-1 (7-37) have been found to have insulinotropic activity. The invention pertains to a composition comprising an acid addition salt of GLP-I (7-37) and to a composition comprising a carboxylate salt of... | 11/21/2006 |
| 7122213 | Supplement foods and pharmaceuticals The present invention provides effective supplement foods and safe pharmaceuticals, each having a hypotensive effect and anti-diabetic effect and no adverse effects. The supplement foods and pharmaceuticals of the present invention comprise squash extract mixed with... | 10/17/2006 |
| 7119110 | Method and composition for preventing or reducing the symptoms of insulin resistance syndrome A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bo... | 10/10/2006 |
| 7115575 | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof The present invention relates to glucopyranosyloxypyrazole derivatives represented by the general formula: wherein R1 represents a hydrogen atom or a lower alkyl group; one of Q1 and T1... | 10/03/2006 |
| 7109242 | Carboxylic compound and medicine comprising the same A compound represented by the following general formula (1), a salt thereof, or an ester thereof: wherein m represents an integer of 0 to 4, n represents an integer of 5 to 9, and R represents hydrogen atom or a ... | 09/19/2006 |
| 7109347 | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents The present invention provides new uses of DPIV-inhibitors of the present invention, and their corresponding pharmaceutically acceptable acid addition salt forms, for treating conditions mediated by DPIV or DPIV-like enzymes, such as cancer and tumors. In a more pre... | 09/19/2006 |
| 7105314 | Method for making human insulin precursors Novel insulin precursors comprising a connecting peptide (mini C-peptide) of preferably up to 6 amino acid residues and comprising at least one Pro are provided. The precursors can be converted into human insulin or desB30 human insulin. ... | 09/12/2006 |
| 7101838 | Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts The present invention provides for a method to prevent accelerated atherosclerosis in a subject predisposed thereto which comprises administering to the subject a polypeptide derived from soluble receptor for advanced glycation endproduct in an amount effective to p... | 09/05/2006 |
| 7101910 | Compounds for the treatment of metabolic disorders Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed. ... | 09/05/2006 |
| 7094763 | Substituted fused heterocyclic C-glycosides This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X. ... | 08/22/2006 |
| 7087215 | Methods of administering and enhancing absorption of pharmaceutical agents Pharmaceutical compositions comprising a macromolecular pharmaceutical agent in mixed micellar form are disclosed. The mixed micelles are formed from an alkali metal alkyl sulfate, and at least three different micelle-forming compounds as described in the specificat... | 08/08/2006 |
| 7083798 | Method of immunomodulatory treatment of insulin dependent diabetes mellitus using mycobacterial cell wall compositions The present invention relates generally to a method of immunomodulating therapy and pharmaceutical compositions useful for same. More particularly, the present invention provides a method of ameliorating the effects of autoimmune conditions. Even more particularly, ... | 08/01/2006 |
| 7081260 | α-Glucosidase inhibitors from a natural source The present invention relates to a method for providing α-glucosidase inhibition to a subject by administering a pharmaceutical composition comprising a α-glucosidase inhibitory agent selected from pipataline (formula 1a), sesamin (formula 1b), pellitorine (Formul... | 07/25/2006 |
| 7074388 | Water stabilized medicinal aerosol formulation This invention relates to a medicinal aerosol suspension formulation and more particularly, to a medicinal aerosol formulation containing a particulate drug or a combination of at least two particulate drugs, a propellant and a stabilizing agent comprising a water a... | 07/11/2006 |
| 7067155 | Anti-inflammatory humate compositions and methods of use thereof The invention relates to an anti-inflammatory composition containing humate, such as insoluble, granular, other insoluble, or soluble humate, particularly Menefee Humate®. The invention also includes other anti-inflammatory compositions containing humate and at lea... | 06/27/2006 |
| 7067498 | Polymer controlled induced viscosity fiber system and uses thereof The present invention relates generally to a method of blunting the postprandial glycemic response in a human by feeding an induced viscosity fiber system. The invention also relates to an induced viscosity fiber system and the liquid products that incorporate the i... | 06/27/2006 |
| 7056539 | Process and product extracted from herbal composition useful in controlling diabetes mellitus type II An active substance is extracted from an herbal composition which comprises: Centaurii umbellatum, Gentianaceae (centaury plant), Teraxacum officinale, Asteraceae (dandelion root), Juniperi communis L, Cupresaceae (juniper berry), Urticae dio... | 06/06/2006 |
| 7056892 | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof The present invention relates to glucopyranosyloxypyrazole derivatives represented by the general formula: wherein R1 represents a hydrogen atom or a lower alkyl group; one of Q1 and T1... | 06/06/2006 |
| 7056900 | Disaccharide derivatives for treating hyperglycaemia The invention relates to the use of the disaccharide derivatives 3′-aminosucrose, sucrose-C6-acid and palatinose-C6′-acid and/or of an amide or alkyl ester thereof for the prevention or treatment of hyperglycemias. ... | 06/06/2006 |
| 7056899 | Disaccharide derivatives for treating hyperglycaemia The invention relates to the use of the disaccharide derivatives 3′-aminosucrose, sucrose-C6-acid and palatinose-C6′-acid and/or of an amide or alkyl ester thereof for the prevention or treatment of hyperglycemias. ... | 06/06/2006 |
| 7053116 | Methods for protecting cells from amyloid toxicity and for inhibiting amyloid protein production In accordance with the present invention, there are provided novel methods of blocking amyloid protein toxicity in cells using polycylic compounds. Also provided are novel methods of decreasing amyloid protein production in cells and methods of inhibiting cell death... | 05/30/2006 |
| 7033616 | Extracts, compounds and pharmaceutical compositions having anti-diabetic activity and their use The invention relates inter alia to pharmaceutical compositions containing an extract obtainable from a plant of the genus Trichocaulon or Hoodia having anti-diabetic activity; and to the use of such extracts and to compound (1) as herein defined and i... | 04/25/2006 |
| 7026294 | Method of use of peptide antagonists of zonulin to prevent or delay the onset of diabetes A method for prevention of delaying the onset of diabetes using peptide antagonists of zonulin, is disclosed. ... | 04/11/2006 |
| 7022722 | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis The subject invention provides pharmaceutical compounds useful in the treatment of Type II diabetes. These compounds are advantageous because they are readily metabolized by the metabolic drug detoxification systems. Particularly, thiazolidinedione analogs that have... | 04/04/2006 |
| 7022682 | Method for the treatment of diabetes The present invention provides for a method for treatment and prevention of Type II Diabetes Mellitus and its complications comprising the step of administering to a patient a therapeutically-effective amount of Rhamnan Sulphate, its functional analogs, or its physi... | 04/04/2006 |
| RE39055 | Hepatoselective pharmaceutical actives The invention provides an analogue of a pharmaceutical active whose molecular weight is less than 25,000 Daltons, the analogue comprising a pharmaceutical active whose molecular weight is less than 25,000 Daltons covalently linked to a pendant molecular group wherei... | 04/04/2006 |
| 7018419 | Microporous encapsulated endocrine cell disks, biconcave disks and multidimpled chambers for hormonal replacement An endocrine cell microdisk or macrodisk containing pancreatic cells for transplantation into an animal body is formed with a lateral extent much greater than its thickness to thereby enhance its diffusional capability. One or more concavities may also be formed the... | 03/28/2006 |
| 7015201 | Pyrazole derivatives and diabetic medicine containing them The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine. ... | 03/21/2006 |
| 6992060 | Prolonged efficacy of islet neogenesis therapy methods with a gastrin/CCK receptor ligand and an EGF receptor ligand composition in subjects with preexisting diabetes Compositions and methods are provided for achieving in vivo islet cell regeneration in subjects with preexisting diabetes. The methods comprise short term treatment with a composition having a gastrin/cholecystokinin receptor ligand and an EGF receptor ligand. Treat... | 01/31/2006 |
