...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Number | Title | Issue Date |
| 4427686 | Pharmacologically active benzopyranotriazole compounds A compound of the formula (I): ##STR1## wherein R1 is hydrogen or C1-6 alkyl; R2, R3 and R4 are the same or different and are chosen from hydrogen, hydroxyl, halogen, C1-4 alkyl, C1-4 | 01/24/1984 |
| 4421927 | New cinnamoyl-cinnamic acid derivative, and its use as pharmaceutical The present invention relates to a new cinnamoyl-cinnamic acid derivative selected from the group constituted by: (i) the m-cinnamoyl-cinnamic acid derivatives of formula ##STR1## in which: Xo,X1,X2,X3,X4 | 12/20/1983 |
| 4419357 | 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinones useful as antiallergic agents are described herein. The compounds are prepared by the reaction of an appropriate 2-amino-N-(1H-tetrazol-5-yl)benzamide with an appropriate ortho ester.... | 12/06/1983 |
| 4416892 | Method of treating hypersensitivity disease with benzoxazole derivatives The invention relates to a method for the prophylactic or therapeutic treatment of an immediate hypersensitivity disease, which comprises administering to a mammal, including a human, a compound of the following formula ##STR1## in which the gro... | 11/22/1983 |
| 4384000 | Method for treatment of various dermatological conditions The method for treatment of various cellular diseases and, more particularly, various dermatological conditions is comprised of administrating dosages of diphenoxylate hydrochloride either topically and/or systemically.... | 05/17/1983 |
| 4367224 | Stable dithranol compositions in anhydrous vehicles Stable dithranol compositions in anhydrous vehicles therapeutically effective as topical treatment for skin disorders such as psoriasis, eczema and seborrheic dermatitides are disclosed. Incorporation of oxalic acid in anhydrous dithranol compositions has... | 01/04/1983 |
| 4353899 | Novel 16-methyl-pregnane The novel product, 9,11ଲ-dichloro-16-methyl-21-oxycarbonyldicyclohexylmeth oxy-Ɗ1,4 -pregnadiene-3,20-dione, having surprenant "in loco" anti-inflammatory activity without any systemic anti-inflammatory activity and its... | 10/12/1982 |
| 4323688 | Benzimidazole-2-carboxylic acid and derivatives thereof Novel substituted heterocyclyl compounds of the formula ##STR1## in which R is a free, esterified or amidated carboxyl group or a free, etherified or esterified hydroxymethyl group, R1 is an aliphatic, cycloaliphatic, aromatic, araliphatic... | 04/06/1982 |
| 4284630 | Stabilized water-in-oil emulsions Stable water-in-oil emulsions useful as vehicles for cosmetics or for therapeutic compositions to be topically applied are disclosed. The emulsions utilize a concentration of from 0.2 to 2% by weight of magnesium oxide or magnesium hydroxide as a stabiliz... | 08/18/1981 |
| 4277474 | Treatment of allergic symptoms with propanone derivatives New propanone derivatives, useful for treating allergic diseases, the pharmacologically allowable salts thereof, their manufacturing process and pharmaceutical composition containing at least one of them as the active ingredient.... | 07/07/1981 |
| 4272527 | Medicinal preparation containing the extract of peat wax resin A medicinal preparation for treatment of skin diseases consists of an active principle, which is an ethanol extract of peat wax resin, obtained by ethanol extraction of peat wax resin at the ethyl alcohol boiling point, and a pharmaceutical vehicle. The p... | 06/09/1981 |
| 4265902 | Therapeutic treatment of horses Therapeutically treating horses suffering from tail and mane eczema by systemically administering to said horses a small but effective amount of allantoin.... | 05/05/1981 |
| 4239781 | Method for treating skin ailments A method for treating skin ailments comprising applying polyethylene glycol or other lower polyalkylene glycol to the ailing portion of the skin.... | 12/16/1980 |
| 4235889 | Therapeutic agent for the external treatment of psoriasis, tinea and eczemas The subject of the invention is a pharmaceutical composition for the external treatment of psoriasis, tinea and eczemas, comprising coconut oil, palm kernel oil, an extract of Laurus nobilis (Linn.) and an emulsifier.... | 11/25/1980 |
| 4216155 | Process for the preparation of novel benzopyrane derivatives The present invention relates to novel benzopyrane derivatives, especially 3-oxaloamino-4-oxo-4H-1-benzopyrane derivatives of the formula I ##STR1## in which Ph is substituted or unsubstituted 1,2-phenylene, R is free, esterified or amidated carboxyl... | 08/05/1980 |
| 4194007 | -Hydroxyretinoic acid, -ketoretinoic acid and mixtures and their use in treating skin conditions Discloses -hydroxyretinoic acid, -ketoretinoic acid and mixtures thereof as well as compositions containing the same that are useful in the treatment of skin diseases, and particularly skin diseases exhibiting abnormal keratinization.... | 03/18/1980 |
| 4160860 | Active plant extracts of hypoxidaceae and their use Plant material derived from the family Hypoxidaceae is heated at a temperature of at least 60° C. for a sufficient period to ensure enzyme destruction and is then extracted at a temperature of 0°-30° C. with aqueous alcohol containing 30-75 volume ... | 07/10/1979 |
| 4159279 | Nuclear substituted 2-hydroxyphenylmethanesulfamic acids Nuclear substituted 2-hydroxyphenylmethanesulfamic acids and their pharmaceutically acceptable salts wherein the phenyl nucleus is substituted with 2 to 4 nuclear substituents and which are useful saluretic-diuretics and anti-inflammatories are disclosed.... | 06/26/1979 |
| 4133811 | 13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes Steroids having the formula ##STR1## wherein X is --S--, ##STR2## R1 is alkyl or aryl; R2 is hydrogen or halogen; and R3 is hydrogen, fluorine or methyl; can be used as antiinflammatory agents.... | 01/09/1979 |
| 4116978 | D-Homo oxasteroids Steroids having the formula ##STR1## or the 1,2-dehydro derivative thereof, wherein R1 is hydrogen, acyloxy, halogen, or hydroxy; R2 is hydrogen or alkyl; R3 is alkyl; R4 is carbonyl, ଲ-hydroxymethyle... | 09/26/1978 |
| 4107161 | Bis(triamcinolone acetonide)-4,4'-methylenebis-(3-methoxy-2-naphthoate) Bis(triamcinolone acetonide) 4,4'-methylene-bis(3-methoxy-2-naphthoate), method of preparing the same by preparing a reactive derivative of 4,4'-methylene-bis(3-methoxy-2-naphthoic acid) and reacting such derivative with triamcinoline acetonide. The triam... | 08/15/1978 |
| 4083980 | Derivatives of quinazolone Compounds of the formula ##STR1## wherein A is --CH.dbd.CH--, --CH.dbd.N-- or --S--, R1 is hydrogen, lower alkyl, lower alkoxy, amino, acetylamino, cyano, tetrazol-5-yl, --COR3 or a fused benzene ring, Where R3 is lower al... | 04/11/1978 |
| 4034075 | Quinaldic acid derivatives Compounds of the general formula (I): ##STR1## in which R1, R2 and R3 may be the same or different and each represents a hydrogen atom, an alkyl group, a nitro group, a halogen atom or a group of the formula --NR... | 07/05/1977 |
| 4033995 | D-homo steroids D-Homo-21-carboxylic acids of the formula ##STR1## the represents a single bond or a double bond; X is a hydrogen atom, a fluorine atom, or methylene; Y is a hydrogen atom, a fluorine atom, or a chlorine atom; Z is methylene, carbonyl, ଲ-hydroxy... | 07/05/1977 |
| 4011326 | 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents Oxazolo[4,5-b]pyridine substituted in the 2-position with a polyhydrobicycloaryl group are topical anti-inflammatory agents. They are prepared by condensing a 2-amino-3-hydroxypyridine with the appropriate carboxylic compound.... | 03/08/1977 |
| 3997535 | Quinoxaline-2-carboxamidotetrazoles Compounds of the general formula I: ##STR1## and pharmaceutically acceptable salts thereof in which: A represents the group ##STR2## or the group ##STR3## linked to the adjacent benzene ring through the nitrogen atom, in which R | 12/14/1976 |
| 3987088 | Cyclic carbonyl compounds Certain fluorenone and anthraquinone compounds, each of which is 2-substituted by a carboxyl group or a salt, ester or optionally substituted amide thereof and each of which is optionally substituted in the 5,6-,7-or 8-position, by a second carboxyl group... | 10/19/1976 |
| 3960892 | 1-Oxo-1H-2-benzothiopyran-3-carboxylic acid derivatives The method comprises administering to an animal a novel pharmaceutical composition containing a substituted-1-oxo-1H-2-benzothiopyran-3-carboxylic acid to inhibit antigen-antibody reaction in said animal. Representative of the compounds that can be u... | 06/01/1976 |
| 3957994 | Topical anti-inflammatory composition and method of use There is disclosed a novel topical anti-inflammatory composition comprising theophylline and 2-pyrrolidone or an N-lower alkyl-2-pyrrolidone.... | 05/18/1976 |
| 3948943 | Aminocarboxylic acid higher alkylamides Compounds of the formula ##EQU1## wherein R1 is lower alkyl or aryl, R2 is hydrogen or, together with R1, ethylene, and R3 is straight or branched alkyl of 8 to 22 carbon atoms; The compounds have useful therapeutic,... | 04/06/1976 |
| 3944584 | Steroidal (16,17-d)cyclohexenes A series of novel steroidal[ 16, 17-d]cyclohexenes having a 9-fluoro group is disclosed herein for use as anti-inflammatory agents.... | 03/16/1976 |
| 3943141 | Tetrazolyl containing naphthyridine 3-carboxamides Compounds of the general formulae I and II and pharmaceutically acceptable salts thereof: ##SPC1## In which: R1 represents a hydrogen atom, a halogen atom, an alkenyl or alkyl group; or a group OR3 or NR3 R4 whe... | 03/09/1976 |
| 3932656 | Article of manufacture for instant release of anti-aggregation and non-thrombogenic agents to biological media Polymeric materials having at least one exposed surface rendered as a release means for platelet aggregation inhibiting agent by serving as a reservoir for release of aggregation inhibiting prostaglandin. The polymeric surface can also be both platelet ag... | 01/13/1976 |