Celebrity Inventors
Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Number | Title | Issue Date |
| 3959369 | Alkanolamine derivatives Novel 1-amidoaryloxy-3-amidoalkylamino-2-propanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart diseases. The compounds possess ଲ-adrenergic blocking act... | 05/25/1976 |
| 3957784 | Bis(4-[4'-hydroxy-5'-carboxy-2'-pyrimidinyl]phenoxy)alkanes 5-Carboxypyrimidine derivatives and their pharmaceutically acceptable basic salts, and their use as antiallergy agents.... | 05/18/1976 |
| 3956328 | S-triazolo(1,5-a)pyridine derivative A compound of the formula (I), ##SPC1## and the non-toxic acid addition salts thereof are disclosed. These compounds and salts are useful as therapeutic agents for allergic diseases.... | 05/11/1976 |
| 3956330 | N,N-diethyl-4-methyl-1-pi-perazinecarboxamide pamoate Asthma is effectively treated by inhalation of powder dispensed from an aerosol suspension of powdered N,N-diethyl-4-methyl-1-piperazinecarboxamide pamoate, which is dispersed as a fine powder, essentially below 10 microns in particle size, which giv... | 05/11/1976 |
| 3953604 | 1-(2-Substituted-chromonyloxy)-2-hydroxy-3-(substituted phenoxy)propanes Definitions: in the following Formulae I, II and IV, R1 represents hydrogen, alkyl of 1 to 4 carbon atoms, or a nontoxic cation, while each of R2, R3, R4, R5, and R6 symbolizes hydrogen, al... | 04/27/1976 |
| 3953598 | Compounds, compositions and methods of use Compounds of the formula ##SPC1## Are useful in the prophylactic treatment of sensitized humans and animals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature. Compositions of these compounds formulated with pharmaceutica... | 04/27/1976 |
| 3952048 | Substituted anilide esters of PGA Substituted anilide esters of PGA1, 15-alkyl-PGA1, and 15(R)-15-alkyl-PGA1, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes... | 04/20/1976 |
| 3952013 | 1-Thiachromone-2-carboxylic acids and derivatives Pharmaceutical compounds of formula I, ##SPC1## in which P, q, r, and T, which may be the same or different, each represent hydrogen, an alkyl, hydroxy, alkoxy, hydroxyalkoxy, alkoxyalkoxy, acetoxy, carboxy, amino, alkylamino, dialkylamino, alkenyl, p-tol... | 04/20/1976 |
| 3952104 | Benzopyran-2-carboxylic acids in the prevention of asthmatic symptoms There are described certain mono-chromone-2-carboxylic acids of formula, ##SPC1## Having one substituent in the 5 or 6 position or having 2 or more substituents in the 5,6,7 or 8 positions. There are also described processes for making the compounds and p... | 04/20/1976 |
| 3950519 | Composition and method of treating asthma An aqueous composition for the treatment of asthma contains from 35 to 50 grams cedar resin per liter of composition, and preferably includes coloring and flavoring additives. The composition is preferably administered in dosages up to 15 c.c. three times... | 04/13/1976 |
| 3948970 | Substituted tolyl esters of PGA1 Substituted tolyl esters of PGA1, 15-alkyl-PGA1, and 15(R)-15-alkyl-PGA1, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes a... | 04/06/1976 |
| 3948955 | 4'-Carboxy-flavone There are provided compounds of the formula: ##SPC1## (wherein R1, R2, R3 and R4, which may be the same or different, each represent hydrogen, hydroxy, alkenyl, alkanoyl or alkyl, and X represents a hydrocarbon ... | 04/06/1976 |
| 3946008 | Substituted benzopyrano[3,4-c]pyridines Substituted benzopyrano[3,4-c]pyridines having the following structural formula are disclosed: ##SPC1## In the above formula, R1 and R2 are hydrogen, a hydroxyl group or a lower alkoxyl group of from 1 to 6 carbon atoms; and X is an ... | 03/23/1976 |
| 3946022 | Piperidine derivatives Compounds of the following general formula are useful as antihistamine agents, antiallergy agents and bronchodilators: ##SPC1## Wherein R represents hydrogen or hydroxy; R1 represents hydrogen; or R and R1 taken together form a secon... | 03/23/1976 |
| 3943141 | Tetrazolyl containing naphthyridine 3-carboxamides Compounds of the general formulae I and II and pharmaceutically acceptable salts thereof: ##SPC1## In which: R1 represents a hydrogen atom, a halogen atom, an alkenyl or alkyl group; or a group OR3 or NR3 R4 whe... | 03/09/1976 |
| 3941785 | Imidazo [5,1-f]-as-triazines Compounds of the general formula: ##SPC1## In which: R1 and R2 which may be the same or different, represent a hydrogen atom or an alkyl group which may optionally be substituted by an aryl group, or represents an alkanoyl, aroyl or ... | 03/02/1976 |
| 3941796 | -(Hydroxy and alkoxy substituted)phenyl--(2-piperidinyl)-methanols -(Hydroxy and alkoxy substituted)phenyl--(2-piperidinyl)methanols of the formula ##SPC1## Where R is hydrogen or lower alkyl, R1 is hydrogen, hydroxy or lower alkoxy, and R2 is phenyl, phenyl-lower alkyl, diphenyl-lower... | 03/02/1976 |
| 3939276 | Cyclic carbonyl compounds Certain fluorenone and anthraquinone compounds, each of which is 2-substituted by a carboxyl group or a salt, ester or optionally substituted amide thereof and each of which is optionally substituted in the 5,6-,7- or 8- position, by a second carboxyl gro... | 02/17/1976 |
| 3939173 | Substituted carbonyl compounds Fluorenone and anthraquinone compounds substituted by at at least one tetrazolyl group in one ring, and further substituted in the other ring, optionally for the fluorenones, have antiallergic activity.... | 02/17/1976 |
| 3937837 | Substituted chromone-3-carbonitriles, carboxamides and carboxylic acids useful for preventing asthmatic symptoms Substituted chromone-3-carbonitriles, carboxamides and carboxylic acids having the structural formula: ##SPC1## Wherein R1 represents hydrogen, halogen, lower alkyl, hydroxy, lower alkoxy, or acyloxy; R2 represents hydrogen, lower al... | 02/10/1976 |
| 3937828 | Substituted pyrano[3,2-c] [1,2]benzothiazine 6,6-dioxides Novel pyrano[3,2-c][1,2]benzothiazine 6,6-dioxides are disclosed, substituted on the 3 position by a lower alkyl, carboxaldehyde, or hydroxymethyl group and, optionally substituted on the 5 position by a lower alkyl group. The corresponding aldehyde thios... | 02/10/1976 |
| 3937719 | (4-Oxo-4H-1-benzopyran-2-yl)-oxamic acid, salts and esters anti-allergic agents Anti-allergic agents present the following structural formula: ##SPC1## In which R is --H, lower alkyl or an alkali metal cation. R2 is alkyl of 1 to 6 carbon atoms or hydroxyalkyl of 2 to 6 carbon atoms.... | 02/10/1976 |
| 3936504 | Anti-allergic pharmaceutical compositions 2-Nitroindane-1,3-dione derivatives are useful in the prophylaxis and treatment of asthma, hay fever and also in the treatment of rhinitis.... | 02/03/1976 |
| 3936563 | Hydroxymethylene-substituted chromone-3-carboxaldehydes, process for their preparation and intermediates produced thereby Novel (hydroxymethylene) chromone derivatives of the general formula I: ##SPC1## wherein n represents 1 or 2, are prepared by reacting a cycloalkanone II with a boron trifluoride compound and acetic anhydride to obtain novel boron complex intermediates of... | 02/03/1976 |
| 3935196 | Useful pro-drug forms of theophylline There is provided novel and useful pro-drug forms of theophylline having the formula: ##SPC1## Wherein R represents a member selected from the group consisting of a straight or branched C4 -C20 alkyl group, a straight or branched ... | 01/27/1976 |
| 3933822 | Azapurinones 8-Azapurin-6-ones substituted in the 2-position by a phenyl group carrying in a meta-position a sulphamoyl substituent, and also a hydroxy, alkoxy or alkylthio substituent para with respect to the said sulphamoyl grouping, and pharmaceutically acceptable ... | 01/20/1976 |
| 3933845 | Benzopyranyltetrazoles There are described compounds of formula I, ##SPC1## in which R5, R6, R7 and R8, which may be the same or different, are hydrogen, alkyl C2 to 6, alkoxy C2 to 8, hydroxy-alkoxy C3 to 8, and R5 may be ... | 01/20/1976 |
| 3933844 | Benzopyranyltetrazoles There are described compounds of formula I, ##SPC1## in which R5, r6, r7 and R8, which may be the same or different, are hydrogen, alkyl, halogen, hydroxy, alkenyl, phenyl, alkenyloxy, aralkyl, acyloxy or alkoxy... | 01/20/1976 |
| 3933818 | Heterocyclic compounds Optionally substituted 4-oxo-1,4-dihydrocinnolin-3-ylpropionic acid derivatives, processes for their preparation, pharmaceutical compositions containing them, and a method of treatment using them. A representative compound is ethyl 6-ethyl-1-methyl-4... | 01/20/1976 |
| 3932407 | Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones Optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]-quinazolin-2-ones and 6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]-quinazolin-2-ones or the pharmaceutically acceptable salts thereof are compounds useful as blood platelet anti-aggregative and/or antihyp... | 01/13/1976 |
| 3932486 | Substituted tolyl esters of PGA2 Substituted phenyl and naphthyl esters of PGA2, 15-alkyl-PGA2, and 15(R)-15-alkyl-PGA2, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medi... | 01/13/1976 |
| 3932479 | Lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy... | 01/13/1976 |
| 3932466 | Substituted 2-amino chromones and process for the preparation thereof This invention relates to substituted 2-amino chromones of the general structure I: ##SPC1## wherein R1, R2, R3, and R4 may be hydrogen, hydroxy, lower alkyl or lower alkoxy of 1-6 carbon atoms, halogen such as ... | 01/13/1976 |
| 3931197 | Substituted piperidine derivatives Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##SPC1## Wherein R.sup.1 represents cyclohexyl, phenyl, or substituted phenyl wherein the substituent on the substituted pheny... | 01/06/1976 |
| 3931281 | Substituted anilide ester of PGA.sub.2 Substituted anilide esters of PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as PGA.sub.2, 15-... | 01/06/1976 |
